Novel and Improved Methods for the Prevention and Treatment of Graft-Versus-Host Disease (GVHD).

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889766489
Total Pages : 180 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Novel and Improved Methods for the Prevention and Treatment of Graft-Versus-Host Disease (GVHD). by : Dietlinde Wolf

Download or read book Novel and Improved Methods for the Prevention and Treatment of Graft-Versus-Host Disease (GVHD). written by Dietlinde Wolf and published by Frontiers Media SA. This book was released on 2022-07-28 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Editorial: Novel and Improved Methods for the Prevention and Treatment of Graft-Versus-Host Disease (GVHD)

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Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (137 download)

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Book Synopsis Editorial: Novel and Improved Methods for the Prevention and Treatment of Graft-Versus-Host Disease (GVHD) by : Evelyn Ullrich

Download or read book Editorial: Novel and Improved Methods for the Prevention and Treatment of Graft-Versus-Host Disease (GVHD) written by Evelyn Ullrich and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The European Blood and Marrow Transplantation Textbook for Nurses

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Author :
Publisher : Springer
ISBN 13 : 3319500260
Total Pages : 318 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis The European Blood and Marrow Transplantation Textbook for Nurses by : Michelle Kenyon

Download or read book The European Blood and Marrow Transplantation Textbook for Nurses written by Michelle Kenyon and published by Springer. This book was released on 2018-03-14 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY 4.0 license. This textbook, endorsed by the European Society for Blood and Marrow Transplantation (EBMT), provides adult and paediatric nurses with a full and informative guide covering all aspects of transplant nursing, from basic principles to advanced concepts. It takes the reader on a journey through the history of transplant nursing, including essential and progressive elements to help nurses improve their knowledge and benefit the patient experience, as well as a comprehensive introduction to research and auditing methods. This new volume specifically intended for nurses, complements the ESH-EBMT reference title, a popular educational resource originally developed in 2003 for physicians to accompany an annual training course also serving as an educational tool in its own right. This title is designed to develop the knowledge of nurses in transplantation. It is the first book of its kind specifically targeted at nurses in this specialist field and acknowledges the valuable contribution that nursing makes in this area. This volume presents information that is essential for the education of nurses new to transplantation, while also offering a valuable resource for more experienced nurses who wish to update their knowledge.

Chronic Graft Versus Host Disease

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Author :
Publisher : Cambridge University Press
ISBN 13 : 1139478893
Total Pages : 427 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Chronic Graft Versus Host Disease by : Georgia B. Vogelsang

Download or read book Chronic Graft Versus Host Disease written by Georgia B. Vogelsang and published by Cambridge University Press. This book was released on 2009-04-20 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic graft versus host disease (GVHD) is the most common complication of allogenic bone marrow transplantation. Because of the protracted clinical course of chronic GVHD, transplant centers and hematology/oncology offices are inadequately equipped to manage these immuno-incompetent patients with a multi-system disorder. Practitioners need to be able to recognize and effectively manage chronic GVHD as a late effect of more than half of allogenic transplantations. The text is oriented for the clinician, with chapters covering staging, organ site and system-specific manifestations, treatment options, and supportive care. Drs Georgia B. Vogelsang and Steven Z. Pavletic have been pioneers in the recognition of the multi-organ complexity of this disease and have gathered the input of a variety of subspecialist physicians for this book. This book fills the gap in practical literature on chronic GVHD, providing a comprehensive, up-to-date, and clinically relevant resource for anyone who deals with cancer patients post-transplant.

EBMT HANDBOOK

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Author :
Publisher :
ISBN 13 : 9783031440823
Total Pages : 0 pages
Book Rating : 4.4/5 (48 download)

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Book Synopsis EBMT HANDBOOK by :

Download or read book EBMT HANDBOOK written by and published by . This book was released on 2025 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Novel Molecular Strategies for Prevention of Graft-versus-host Disease by Ex Vivo Tolerance Induction

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Author :
Publisher :
ISBN 13 :
Total Pages : 452 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Novel Molecular Strategies for Prevention of Graft-versus-host Disease by Ex Vivo Tolerance Induction by : Matthew John O'Shaughnessy

Download or read book Novel Molecular Strategies for Prevention of Graft-versus-host Disease by Ex Vivo Tolerance Induction written by Matthew John O'Shaughnessy and published by . This book was released on 2007 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Can We Design Personalized Acute Graft-vs-host Disease Prevention and Treatment Strategies Using Registry Data and Sequential Multiple-assignment Randomized Trials to Improve Disease-free Survival of Blood & Marrow Transplant Patients?

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Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (948 download)

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Book Synopsis Can We Design Personalized Acute Graft-vs-host Disease Prevention and Treatment Strategies Using Registry Data and Sequential Multiple-assignment Randomized Trials to Improve Disease-free Survival of Blood & Marrow Transplant Patients? by : Elizabeth Krakow

Download or read book Can We Design Personalized Acute Graft-vs-host Disease Prevention and Treatment Strategies Using Registry Data and Sequential Multiple-assignment Randomized Trials to Improve Disease-free Survival of Blood & Marrow Transplant Patients? written by Elizabeth Krakow and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "Objective: Graft-versus-host disease (GVHD) is a major complication of allogeneic hematopoietic cell transplantation (AHCT). We investigated whether the Center for International Blood and Marrow Transplant Research registry could be useful for (1) determining if the sequence of administering non-specific, highly T-lymphodepleting (NHTL) therapeutics in GVHD prophylaxis and in refractory GVHD impacts survival and (2) identifying donor- and patient-related factors that may guide individualized selection of classes of immunosuppressant agents over time, i.e. to develop adaptive treatment strategies (ATSs).Method: We employed a backwards induction method derived from reinforcement learning in a large cohort of patients who underwent AHCT for acute myeloid leukemia and myelodysplasia between 1995 and 2007. We devised logistic Q-models that first estimate the optimal treatment for each patient with refractory acute GVHD and then use a pseudo-outcome approach to estimate the optimal patient-specific GVHD prophylaxis, with the goal of maximizing 2-year disease-free survival (DFS).Results: In unadjusted analysis, NHTL prophylaxis and NHTL treatment of refractory acute GVHD were associated with inferior DFS compared to non-NHTL therapeutics. Yet, among the 9563 patients, the Q-model predicted that 4762 (50%) would have a higher probability of 2-year DFS with NHTL prophylaxis. For the 1411 patients with refractory acute GVHD, the Q-model predicted that 492 (35%) would have had a higher probability of 2-year DFS with NHTL salvage therapy. The magnitude of projected patient-specific benefit from choosing the optimal class of agent was modest. The models suggested that patient-specific combinations of characteristics could influence the choice of GVHD prophylaxis and treatment.Conclusions: Retrospective analysis with Q-learning can be used to propose personalized ATSs for GVHD prevention and treatment, which may then be tested in sequentially-randomized clinical trials. An important limitation which threatens the validity of the registry-derived strategies is that lack of detailed information about the indication for each immunosuppressant and other salient patient characteristics may lead to residual confounding." --

Contemporary Bone Marrow Transplantation

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Author :
Publisher : Springer
ISBN 13 : 9783030363574
Total Pages : 0 pages
Book Rating : 4.3/5 (635 download)

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Book Synopsis Contemporary Bone Marrow Transplantation by : Mammen Chandy

Download or read book Contemporary Bone Marrow Transplantation written by Mammen Chandy and published by Springer. This book was released on 2021-03-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone Marrow transplantation or Hematopoietic stem cell transplantation is a life saving procedure in a number of diseases,hematological and non hematological, which fail alternative medical management or have no other treatment options. It has transformed the lives of thousands of patients and their families around the world battling with fatal or debilitating diseases.There are many unique aspects of bone marrow transplantation which makes it very different from solid organ transplants. There is an enormous amount of research going on in this field both at clinical and basic science levels.With the rapidly changing world and field of transplantation, there is a need for an authoritative and up to date resource for transplant professionals. This book titled Contemporary Bone Marrow Transplantation aims to be a reference text comprehensively covering various facets of hematopoietic stem cell transplants with latest insights about the technique and basic science behind it . The book is the product of collective effort of transplant professionals round the world, and will reflect their experience as well as the current standard of care practices in Stem cell transplantation.The book will be divided into different sections focusing on the basic science of bone marrow transplant, the technical aspects of the procedure itself and the supportive care of transplant patients.There will also be a section each on epidemiology, upcoming trends and also case studies , which will discuss real case scenarios from the experience of the authors, to illustrate the practical challenges in managing bone marrow transplant recipients.

Novel Strategies for Managing Graft-versus-host Disease

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Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (116 download)

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Book Synopsis Novel Strategies for Managing Graft-versus-host Disease by : Fiona L. Dignan

Download or read book Novel Strategies for Managing Graft-versus-host Disease written by Fiona L. Dignan and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Atlas of Graft-versus-Host Disease

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Author :
Publisher : Springer
ISBN 13 : 3319469525
Total Pages : 170 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Atlas of Graft-versus-Host Disease by : Jonathan A. Cotliar

Download or read book Atlas of Graft-versus-Host Disease written by Jonathan A. Cotliar and published by Springer. This book was released on 2016-12-30 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: This atlas provides trainees and practicing physicians a visual toolkit to help recognize and manage this difficult condition appropriately. This text highlights the clinical variability of GVHD, and arms readers with the diagnostic clues to categorize patients according to the current grading/staging guidelines. Furthermore, this atlas offers evidence-based diagnostic and treatment algorithms for physicians to use while at patients' bedsides.

Radiation Chimeras

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Publisher : Academic Press
ISBN 13 : 9780127103501
Total Pages : pages
Book Rating : 4.1/5 (35 download)

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Book Synopsis Radiation Chimeras by : O. Van Bekkum

Download or read book Radiation Chimeras written by O. Van Bekkum and published by Academic Press. This book was released on 1967-01-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Haploidentical Transplantation

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Publisher : Springer
ISBN 13 : 3319543105
Total Pages : 330 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Haploidentical Transplantation by : Stefan O. Ciurea

Download or read book Haploidentical Transplantation written by Stefan O. Ciurea and published by Springer. This book was released on 2018-05-03 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, world-renowned experts in the field express well-reasoned opinions on a range of issues and controversies relating to haploidentical transplantation with the aim of providing practicing hematologists with clinically relevant and readily applicable information. Among the areas covered are graft manipulation and methods to control T-cell alloreactivity, the nature of the ideal graft and donor, haploidentical transplantation in pediatric and adult patients with malignant and nonmalignant diseases, immunologic reconstitution following transplantation, complications, and the prevention and treatment of relapse post transplantation. Attention is drawn to the implications of high-impact clinical trials whenever such trials are available. The readily intelligible text is complemented by numerous helpful tables, algorithms, and figures. The book will provide practical support for hematologists and transplant physicians as they attempt to provide optimal care in this exciting but increasingly complex medical specialty.

Thomas' Hematopoietic Cell Transplantation

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118416120
Total Pages : 1416 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis Thomas' Hematopoietic Cell Transplantation by : Stephen J. Forman

Download or read book Thomas' Hematopoietic Cell Transplantation written by Stephen J. Forman and published by John Wiley & Sons. This book was released on 2015-12-14 with total page 1416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully revised for the fifth edition, this outstanding reference on bone marrow transplantation is an essential, field-leading resource. Extensive coverage of the field, from the scientific basis for stem-cell transplantation to the future direction of research Combines the knowledge and expertise of over 170 international specialists across 106 chapters Includes new chapters addressing basic science experiments in stem-cell biology, immunology, and tolerance Contains expanded content on the benefits and challenges of transplantation, and analysis of the impact of new therapies to help clinical decision-making Includes a fully searchable Wiley Digital Edition with downloadable figures, linked references, and more References for this new edition are online only, accessible via the Wiley Digital Edition code printed inside the front cover or at www.wiley.com/go/forman/hematopoietic.

Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation

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Author :
Publisher : Academic Press
ISBN 13 : 0128134399
Total Pages : 450 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation by : Gerard Socie

Download or read book Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation written by Gerard Socie and published by Academic Press. This book was released on 2018-11-22 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation: Models in Discovery and Translation, Second Edition once again provides clinical and scientific researchers with a deep understanding of the current research in this field and the implications for translational practice. By providing an overview of the immune biology of HSCT, an explanation of immune rejection, and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians who need a broad view of the deeply complex processes involved. It then moves on to discuss the immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemia effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent successes, and discussing unanswered questions, this book sums up the current state of HSCT to enhance the prospects for the future. The second edition is fully revised and includes new chapters on microbiome, metabolism, kinase targets, micro-RNA and mRNA regulatory mechanisms, signaling pathways in GVHD, innate lymphoid system development, recovery and function in GVHD, genetically engineered T-cell therapies, immune system engagers for GVHD and graft-versus-tumor, and hematopoietic cell transplant for tolerance induction in solid organ grafts. - Brings together perspectives from leading laboratories and clinical research groups to highlight advances from bench to the bedside - Guides readers through the caveats that must be considered when drawing conclusions from studies with animal models before correlating to clinical allogeneic hematopoietic stem cell transplantation (HSCT) scenarios - Categorizes the published advances in various aspects of immune biology of allogeneic HSCT to illustrate opportunities for clinical applications

Manual of Stem Cell and Bone Marrow Transplantation

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Author :
Publisher : Cambridge University Press
ISBN 13 : 1107661544
Total Pages : 204 pages
Book Rating : 4.1/5 (76 download)

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Book Synopsis Manual of Stem Cell and Bone Marrow Transplantation by : Joseph H. Antin

Download or read book Manual of Stem Cell and Bone Marrow Transplantation written by Joseph H. Antin and published by Cambridge University Press. This book was released on 2013-10-17 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fully revised second edition is a practical manual for all members of the stem cell and bone marrow transplant team.

Holland-Frei Cancer Medicine

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Publisher : John Wiley & Sons
ISBN 13 : 111900084X
Total Pages : 2004 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Holland-Frei Cancer Medicine by : Robert C. Bast, Jr.

Download or read book Holland-Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Blood and Marrow Transplant Handbook

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Author :
Publisher : Springer
ISBN 13 : 3319138324
Total Pages : 437 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Blood and Marrow Transplant Handbook by : Richard T. Maziarz

Download or read book Blood and Marrow Transplant Handbook written by Richard T. Maziarz and published by Springer. This book was released on 2015-04-20 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated and expanded edition developed by the Blood and Marrow Stem Cell Transplant team at Oregon Health & Science University Knight Cancer Institute features the latest medical management guidelines and standards of care for hematopoietic stem cell transplant patients. Spanning the timeline from the initial consultation throughout the transplant process, this handbook includes indications for transplantation and donor selection, treatment guidelines for addressing complications during and after transplant, and recommendations for long-term follow up care. Concise, comprehensive, and easy-to-use, Blood and Marrow Transplant Handbook, 2nd Edition presents a multidisciplinary approach to information for physicians and advanced practice medical providers who care for transplant patients, and also residents, fellows, and other trainees.