Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Nouvelles Nanoparticules A Base De Conjugues Polymeriques Biodegradables Pour Des Applications En Drug Delivery
Download Nouvelles Nanoparticules A Base De Conjugues Polymeriques Biodegradables Pour Des Applications En Drug Delivery full books in PDF, epub, and Kindle. Read online Nouvelles Nanoparticules A Base De Conjugues Polymeriques Biodegradables Pour Des Applications En Drug Delivery ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Nouvelles nanoparticules à base de conjugués polymériques biodégradables pour des applications en drug delivery by : Fethi Bensaid
Download or read book Nouvelles nanoparticules à base de conjugués polymériques biodégradables pour des applications en drug delivery written by Fethi Bensaid and published by . This book was released on 2012 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ce travail de thèse s'inscrit dans le cadre d'une collaboration entre le LHFA à Toulouse et le département CMC (Chemistry Manufacturing and Control) de Sanofi à Vitry-sur-Seine, et a pour but de développer de nouveaux nanovecteurs à base de conjugués polymériques biodégradables et biocompatibles capables d'être utilisés pour la vectorisation de principe actif. Dans le premier chapitre, une étude bibliographique a été détaillée afin de comprendre les principes de la vectorisation et de faire le point sur les principales avancées réalisées pour la vectorisation d'agents thérapeutiques par administration intraveineuse, en particulier à l'aide de polymères biodégradables et biocompatibles, tels que le PLA et le PEG. Dans le second chapitre, tirant profit de la catalyse organique de la ROP, de nouveaux conjugués macromoléculaires à base de PEG-PLA/Taxane, avec une architecture particulière de type " Y " positionnant le PA entre les blocs de PLA et de PEG, ont été synthétisés. Des conjugués de type PEG-PLA-Taxane linéaires ont aussi été préparés pour comparer l'influence de l'architecture sur les propriétés des nanovecteurs. La composition chimique de ces nanoconjugués a été précisément caractérisée à l'aide de plusieurs techniques analytiques (RMN, DOSY, UPLC, SEC...). Dans le troisième chapitre, les conjugués macromoléculaires ont été formulés dans un milieu aqueux pour donner naissance à des nanoparticules de conformation " cœur-couronne ". Les deux différentes architectures permettent d'obtenir des NPs stables. Ensuite, L'utilisation de la spectroscopie RMN dans le D2O a permis de localiser le PA au sein des NPs : à l'interface hydrophile/hydrophobe pour les conjugués " Y " et dans le centre hydrophobe pour les conjugués linéaires. Enfin, les études de libération du PA in vitro ont montré des profils prolongés et différents en fonction de l'architecture et de la nature de l'espaceur : la libération la plus rapide a été obtenue avec la structure " Y " et avec l'espaceur " diglycolique ".
Book Synopsis Applications of Nanocomposite Materials in Drug Delivery by : Inamuddin
Download or read book Applications of Nanocomposite Materials in Drug Delivery written by Inamuddin and published by Woodhead Publishing. This book was released on 2018-06-18 with total page 988 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applications of Nanocomposite in Drug Delivery discusses and explores the applications of nanocomposites in the area of drug delivery. Starting with a scientific understanding of drug delivery fundamentals, the book explores the utility of nanocomposites in the area of controlled, transdermal, osteo-articular tuberculosis and stimulus sensitive drug delivery applications. The book intricately details and discusses a variety of methods for their preparation, while also highlighting specific applications of nanocomposites in targeted drug delivery. Discusses nanocomposite and nanotechnology for drug delivery Outlines the mechanisms involved in targeted drug delivery using nanocomposites Includes synthesis methods for nanocomposites used in controlled drug delivery Lists various applications of nanocomposites in drug delivery
Book Synopsis A New Generation of Polymer Nanoparticles for Drug Delivery by : Cédric Chauvierre
Download or read book A New Generation of Polymer Nanoparticles for Drug Delivery written by Cédric Chauvierre and published by Editions Universitaires Europeennes. This book was released on 2010-09 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the main interest of using polymer nanoparticles as drug carrier systems is to control the delivery of the drug and of their biodistribution. It was clearly demonstrated that surface properties of nanoparticles were the key factor which determined the in vivo fate of such a cerrier. While a neutral (stealth(r)) system of appropriate circulation lifetime as poly(ethylene glycol) chains coated nanoparticles is already of interest, an additional positive function can be feasible by a proper design of the exposed nanoparticle surface by using polysaccharide chains which are involved in tissue addressing. In this thesis, monodisperse biodegradable nanoparticles were developed from an original redox radical polymerization reaction of alkylcyanoacrylates in emulsion and requiring only one step in aqueous media. The nanoparticle surfaces exhibited polysaccharides that maintain their biological properties. The nanoparticles were very stable, and their characteristics can be modulated. This offers a new strategy for the design of modular biomimetic nanoparticles as drug carrier systems with multiple functions, with applications such as blood substitutes.
Book Synopsis Surfactant-free Biodegradable Nanoparticles for Antioxidant Drug Delivery and Imaging Applications by : Barrett James Nehilla
Download or read book Surfactant-free Biodegradable Nanoparticles for Antioxidant Drug Delivery and Imaging Applications written by Barrett James Nehilla and published by . This book was released on 2008 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Scientific Canadian Mechanics' Magazine and Patent Office Record by : Canada. Patent Office
Download or read book Scientific Canadian Mechanics' Magazine and Patent Office Record written by Canada. Patent Office and published by . This book was released on 1966-03 with total page 1070 pages. Available in PDF, EPUB and Kindle. Book excerpt:
