Food Protein Induced Enterocolitis (FPIES)

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Author :
Publisher : Springer Nature
ISBN 13 : 3030212297
Total Pages : 241 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Food Protein Induced Enterocolitis (FPIES) by : Terri Faye Brown-Whitehorn

Download or read book Food Protein Induced Enterocolitis (FPIES) written by Terri Faye Brown-Whitehorn and published by Springer Nature. This book was released on 2019-08-20 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book is a first-of-its-kind resource, comprehensively guiding readers through the epidemiology, pathophysiology, recent diagnostic criteria, and management options for patients with Food Protein-Induced Enterocolitis Syndrome (FPIES). Food-Protein Induced Enterocolitis Syndrome: Diagnosis and Management opens with a historical perspective of this condition, before moving into discussions of epidemiology and pathophysiology. FPIES can be difficult to diagnose as the symptoms overlap with multiple other conditions, and so clear differential diagnosis will be reviewed for both chronic FPIES, as well as acute FPIES. Later chapters are case-based, providing detailed multiple perspectives on the diagnosis and management of FPIES in patients with varying complicating factors and severity. Later chapters will tackle issues of quality of life in patient care, nutritional management for patients, and discussing working with parents and families to improve communication and at-home care. Parents, families and caregivers will also find chapters useful and relatable. A final chapter will look to the future of FPIES, addressing new research, guidelines, and implications for clinicians working with pediatric patients with FPIES, and for their families. Concise and practical, this book will be an ideal reference for allergists, pediatricians, family practice clinicians, gastroenterologists, nutritionists, and all other health care providers who encounter FPIES, and assist them in providing up-to-date, quality care for pediatric patients affected by this condition.

Finding a Path to Safety in Food Allergy

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Author :
Publisher : National Academies Press
ISBN 13 : 0309450314
Total Pages : 575 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Finding a Path to Safety in Food Allergy by : National Academies of Sciences, Engineering, and Medicine

Download or read book Finding a Path to Safety in Food Allergy written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-05-27 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past 20 years, public concerns have grown in response to the apparent rising prevalence of food allergy and related atopic conditions, such as eczema. Although evidence on the true prevalence of food allergy is complicated by insufficient or inconsistent data and studies with variable methodologies, many health care experts who care for patients agree that a real increase in food allergy has occurred and that it is unlikely to be due simply to an increase in awareness and better tools for diagnosis. Many stakeholders are concerned about these increases, including the general public, policy makers, regulatory agencies, the food industry, scientists, clinicians, and especially families of children and young people suffering from food allergy. At the present time, however, despite a mounting body of data on the prevalence, health consequences, and associated costs of food allergy, this chronic disease has not garnered the level of societal attention that it warrants. Moreover, for patients and families at risk, recommendations and guidelines have not been clear about preventing exposure or the onset of reactions or for managing this disease. Finding a Path to Safety in Food Allergy examines critical issues related to food allergy, including the prevalence and severity of food allergy and its impact on affected individuals, families, and communities; and current understanding of food allergy as a disease, and in diagnostics, treatments, prevention, and public policy. This report seeks to: clarify the nature of the disease, its causes, and its current management; highlight gaps in knowledge; encourage the implementation of management tools at many levels and among many stakeholders; and delineate a roadmap to safety for those who have, or are at risk of developing, food allergy, as well as for others in society who are responsible for public health.

Middleton's Allergy

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Author :
Publisher :
ISBN 13 : 9780323056595
Total Pages : 0 pages
Book Rating : 4.0/5 (565 download)

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Book Synopsis Middleton's Allergy by :

Download or read book Middleton's Allergy written by and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This best-selling resource has a worldwide reputation as the leader in its field. Focusing on human immunology and biology, while also reporting on scientific experimentation and advancement, it provides comprehensive coverage of state-of-the-art basic science as well as authoritative guidance on the practical aspects of day-to-day diagnosis and management. This new edition includes 700 full-color illustrations and a new, more accessible format to make finding information a snap for the busy practitioner. And this Expert Consult Edition offers online access to the complete contents of the 2-volume set, fully searchable, and much more. Includes a glossary of allergy and immunology for quick and easy reference. Contains keypoints and clinical pearls highlighted to find important information quickly. links to useful online resources both for you and for your patients. Offers contributions from hundreds of international authorities for world-class expertise in overcoming any clinical challenge.

Go Dairy Free

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Author :
Publisher : BenBella Books
ISBN 13 : 194688524X
Total Pages : 442 pages
Book Rating : 4.9/5 (468 download)

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Book Synopsis Go Dairy Free by : Alisa Fleming

Download or read book Go Dairy Free written by Alisa Fleming and published by BenBella Books. This book was released on 2018-06-12 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: If ONE simple change could resolve most of your symptoms and prevent a host of illnesses, wouldn't you want to try it? Go Dairy Free shows you how! There are plenty of reasons to go dairy free. Maybe you are confronting allergies or lactose intolerance. Maybe you are dealing with acne, digestive issues, sinus troubles, or eczema—all proven to be associated with dairy consumption. Maybe you're looking for longer-term disease prevention, weight loss, or for help transitioning to a plant-based diet. Whatever your reason, Go Dairy Free is the essential arsenal of information you need to change your diet. This complete guide and cookbook will be your vital companion to understand dairy, how it affects you, and how you can eliminate it from your life and improve your health—without feeling like you're sacrificing a thing. Inside: • More than 250 delicious dairy-free recipes focusing on naturally rich and delicious whole foods, with numerous options to satisfy those dairy cravings • A comprehensive guide to dairy substitutes explaining how to purchase, use, and make your own alternatives for butter, cheese, cream, milk, and much more • Must-have grocery shopping information, from sussing out suspect ingredients and label-reading assistance to money-saving tips • A detailed chapter on calcium to identify naturally mineral-rich foods beyond dairy, the best supplements, and other keys to bone health • An in-depth health section outlining the signs and symptoms of dairy-related illnesses and addressing questions around protein, fat, and other nutrients in the dairy-free transition • Everyday living tips with suggestions for restaurant dining, travel, celebrations, and other social situations • Infant milk allergy checklists that describe indicators and solutions for babies and young children with milk allergies or intolerances • Food allergy- and vegan-friendly resources, including recipe indexes to quickly find gluten-free and other top food allergy-friendly options and fully tested plant-based options for every recipe

AARP Allergic Girl

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118370287
Total Pages : 224 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis AARP Allergic Girl by : Sloane Miller

Download or read book AARP Allergic Girl written by Sloane Miller and published by John Wiley & Sons. This book was released on 2012-04-19 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: AARP Digital Editions offer you practical tips, proven solutions, and expert guidance. AARP Allergic Girl is an indispensable guide for living a full life with food allergies--from an Allergic Girl who lives it. Millions of Americans concerned about adverse reactions to food are seeking the advice of medical professionals and receiving a diagnosis of food allergies. Allergic Girl Sloane Miller, a leading authority on food allergies, has been allergic since childhood. She now lives a full, enjoyable life full of dining out, dating, attending work functions, and traveling. With tested strategies and practical solutions to everyday food allergy concerns, Allergic Girl shows how readers can enjoy their lives too. Informed by personal narratives laced with humor and valuable insights, Allergic Girl is a breakthrough lifestyle guide for food-allergic adults, their families, and loved ones. In Allergic Girl, you will discover: How to find the best allergist and get a correct diagnosis How to create positive relationships with family, friends, and food How to build a safe environment wherever you are Real-world scenarios scripted from the author's life as well her work with clients and other leaders in the field Enjoy your food-allergic life to the fullest. Let Allergic Girl show you how.

Allergy-Free and Easy Cooking

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Publisher : National Geographic Books
ISBN 13 : 1607742918
Total Pages : 0 pages
Book Rating : 4.6/5 (77 download)

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Book Synopsis Allergy-Free and Easy Cooking by : Cybele Pascal

Download or read book Allergy-Free and Easy Cooking written by Cybele Pascal and published by National Geographic Books. This book was released on 2012-12-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of 75 completely allergen-free recipes ready in 30 minutes or less, perfect for food allergic kids and busy professionals who need to get meals on the table swiftly. With her acclaimed cookbooks and loyal following, Cybele Pascal has been pioneering allergy-friendly cooking for more than a decade. As the mother of two kids with food allergies, Pascal knows the value of weeknight-friendly allergy-free recipes that can be prepped and on the table in half an hour without sacrificing flavor or texture. Through adept ingredient substitutions and easy-to-follow techniques, Pascal excels at providing enticing recipes that steer clear of the top eight allergens and appeal to home cooks who need to avoid dairy, eggs, wheat, soy, peanuts, tree nuts, fish, shellfish, and sesame. Pascal’s allergy-friendly versions of favorites like Creamy Mac ‘n’ “Cheese,” Buffalo Wings with Ranch Dressing, Chicken Mole Soft Tacos, Gnocchi, Deep Dish Pizza with Italian Sausage, and Beef and Broccoli Stir-Fry have all the appeal of the originals, and are perfect for food allergic kids and busy professionals. Allergy-Free and Easy Cooking is a delightful solution that will help you get flavorful, safe meals on the table swiftly.

The Allergy-Free Cookbook

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Author :
Publisher : Running Press Adult
ISBN 13 : 0786745045
Total Pages : 304 pages
Book Rating : 4.7/5 (867 download)

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Book Synopsis The Allergy-Free Cookbook by : Eileen Rhude Yoder

Download or read book The Allergy-Free Cookbook written by Eileen Rhude Yoder and published by Running Press Adult. This book was released on 2009-03-03 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Do you have food allergies? This cookbook offers more than 150 tasty recipes and menus designed to eliminate the 8 major food allergens without sacrificing taste and nutrition. Eight major food allergens cause more than 90% of all reactions to food so here's a cookbook with easy step-by-step recipes perfect for you, your family, and even the youngest eater to enjoy. In addition to helpful charts and reassuring advice, The Allergy-Free Cookbook provides: Tips for shopping allergy-free including quick takes to demystify labels Substitution guides so you can continue to cook your favorite dishes with new ingredients Time-saving tips for special occasions, especially when cooking for kids, making birthday parties, school snacks and more easy and breezy Written by a nutritionist with decades of experience and empathy, The Allergy-Free Cookbook puts you back in control of your diet quite deliciously!

The Allergen-Free Baker's Handbook

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Author :
Publisher : Celestial Arts
ISBN 13 : 1587613484
Total Pages : 202 pages
Book Rating : 4.5/5 (876 download)

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Book Synopsis The Allergen-Free Baker's Handbook by : Cybele Pascal

Download or read book The Allergen-Free Baker's Handbook written by Cybele Pascal and published by Celestial Arts. This book was released on 2009-12-22 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Free to Eat Sweets! The number of people with food allergies is skyrocketing, leaving puzzled cooks and anxious parents eager to find recipes for “normal” foods that are both safe and delicious. The Allergen-Free Baker’s Handbook features 100 tried-and-true recipes that are completely free of all ingredients responsible for 90 percent of food allergies, sparing bakers the all-too-common frustration of having to make unsatisfactory substitutions or rework recipes entirely. To make things even easier, energized and empathetic mom Cybele Pascal demystifies alternative foodstuffs and offers an insider’s advice about choosing safe products and sources for buying them. As the head baker for a food-allergic family, food writer Pascal shares her most in-demand treats and how to make them work without allergenic ingredients. Her collection includes a delightfully familiar array of sweets and savory goodies that are no longer off-limits, from Glazed Vanilla Scones, Cinnamon Rolls, and Lemon-Lime Squares to Chocolate Fudge Brownies, Red Velvet Cake, and every kid’s favorite: Pizza. In addition to being a lifeline for people with food allergies, sensitivities, and intolerances, these entirely vegan recipes are perfect for anyone looking to avoid artificial and refined ingredients, and those interested in baking with healthful new gluten-free flours such as quinoa, sorghum, and amaranth. Best of all, Pascal has fine-tuned each recipe to please the palates of the most exacting critics: her young sons. Lennon and Monte like these tasty treats even better than their traditional counterparts, and you will too!

Learning to Bake Allergen-Free

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Author :
Publisher : The Experiment
ISBN 13 : 1615190538
Total Pages : 305 pages
Book Rating : 4.6/5 (151 download)

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Book Synopsis Learning to Bake Allergen-Free by : Colette Martin

Download or read book Learning to Bake Allergen-Free written by Colette Martin and published by The Experiment. This book was released on 2012-06-19 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explains the most common food allergens and gluten, offers tips for adapting recipes, and provides recipes for meals, snacks, and desserts.

The Allergy-Free Pantry

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Author :
Publisher : The Experiment
ISBN 13 : 1615192085
Total Pages : 330 pages
Book Rating : 4.6/5 (151 download)

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Book Synopsis The Allergy-Free Pantry by : Colette Martin

Download or read book The Allergy-Free Pantry written by Colette Martin and published by The Experiment. This book was released on 2014-01-01 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Features allergy-free recipes made with flour blends, non-dairy milks, and egg replacers, including pancakes, spinach pasta, and sunflower butter cups.

Food Allergy and Intolerances

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Publisher :
ISBN 13 :
Total Pages : 28 pages
Book Rating : 4.:/5 (327 download)

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Book Synopsis Food Allergy and Intolerances by :

Download or read book Food Allergy and Intolerances written by and published by . This book was released on 1993 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses the differences between food allergies and food intolerances; allergy symptoms; common food allergies; cross reactivity; differential diagnoses; diagnosis of food allergies; exercise-induced food allergies; food allergies in infants and children; controversial issues surrounding food allergies; and treatment of food allergies.

Plant Food Allergens

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Publisher : John Wiley & Sons
ISBN 13 : 0470995165
Total Pages : 238 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Plant Food Allergens by : E. N. Clare Mills

Download or read book Plant Food Allergens written by E. N. Clare Mills and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant Food Allergens is concerned with a paradox of immense, potentially life-threatening significance to about 1 in 100 adults and 1 in 10 children. The paradox is that certain nutritious proteins from wholesome foods can act as if the were harmful, sometimes deadly poisons, to these people who possess an allergy to them. In order to study the complex problems of food allergy a EU funded network, called PROTALL was set up, bringing together a wide range of clinicians and scientists. This important book is largely based on the outcome of its investigations. Written by over 30 acknowledged experts and carefully edited by Dr Clare Mills and Professor Peter Shewry, themselves well known internationally; this important work covers all major aspects of the subject. Commencing with introductory chapters, the comprehensive contents of Plant Food Allergens includes details of the major allergens including: plant lipid transfer proteins, the 2S albumin proteins, the cereal á-amylase/trypsin family, latex and plant chitinases, profilins, bet v 1-homologous allergens and plant seed globulins. The book concludes with important chapters on the assessment of the allergenicity of novel and GM foods, and the monitoring of and technological effects on allergenicity of proteins in the food industry. Plant Food Allergens is an essential purchase for a wide range of scientists and clinicians including plant and agricultural scientists, chemists, allergy specialists, food scientists and technologists, pharmacologists, physiologists and nutritionists. Libraries in all research establishments and universities researching and teaching these subjects will need copies of this important book on their shelves Dr Clare Mills is based at The Institute of Food Research, Norwich, UK. Professor Peter Shewry is based at Rothamsted Research, Harpenden, UK.

Don't Kill the Birthday Girl

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Author :
Publisher : Crown
ISBN 13 : 0307588130
Total Pages : 242 pages
Book Rating : 4.3/5 (75 download)

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Book Synopsis Don't Kill the Birthday Girl by : Sandra Beasley

Download or read book Don't Kill the Birthday Girl written by Sandra Beasley and published by Crown. This book was released on 2011-07-12 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: A beautifully written and darkly funny journey through the world of the allergic. Like twelve million other Americans, Sandra Beasley suffers from food allergies. Her allergies—severe and lifelong—include dairy, egg, soy, beef, shrimp, pine nuts, cucumbers, cantaloupe, honeydew, mango, macadamias, pistachios, cashews, swordfish, and mustard. Add to that mold, dust, grass and tree pollen, cigarette smoke, dogs, rabbits, horses, and wool, and it’s no wonder Sandra felt she had to live her life as “Allergy Girl.” When butter is deadly and eggs can make your throat swell shut, cupcakes and other treats of childhood are out of the question—and so Sandra’s mother used to warn guests against a toxic, frosting-tinged kiss with “Don’t kill the birthday girl!” It may seem that such a person is “not really designed to survive,” as one blunt nutritionist declared while visiting Sandra’s fourth-grade class. But Sandra has not only survived, she’s thrived—now an essayist, editor, and award-winning poet, she has learned to navigate a world in which danger can lurk in an unassuming corn chip. Don’t Kill the Birthday Girl is her story. With candor, wit, and a journalist’s curiosity, Sandra draws on her own experiences while covering the scientific, cultural, and sociological terrain of allergies. She explains exactly what an allergy is, describes surviving a family reunion in heart-of-Texas beef country with her vegetarian sister, delves into how being allergic has affected her romantic relationships, exposes the dark side of Benadryl, explains how parents can work with schools to protect their allergic children, and details how people with allergies should advocate for themselves in a restaurant. A compelling mix of memoir, cultural history, and science, Don’t Kill the Birthday Girl is mandatory reading for the millions of families navigating the world of allergies—and a not-to-be-missed literary treat for the rest of us.

Allergen Management in the Food Industry

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Publisher : John Wiley & Sons
ISBN 13 : 1118060288
Total Pages : 628 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Allergen Management in the Food Industry by : Joyce I. Boye

Download or read book Allergen Management in the Food Industry written by Joyce I. Boye and published by John Wiley & Sons. This book was released on 2011-01-14 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively addresses the sources of allergenic contaminants in foods, their fate during processing, and the specific measures that need to be taken to minimize their occurrence in foods. The book provides up-to-date information on the nine major allergens (as well as other emerging allergens) and practical guidelines on how these allergens can be identified and controlled during production and processing. Starting with an introduction to food allergens, the book follows with sections on food allergen management during production and processing, guidelines for the processing of specific allergen-free foods, techniques for hypo-allergenization and allergen detection, and allergen-free certification.

Crazy Sexy Kitchen

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Author :
Publisher : Hay House, Inc
ISBN 13 : 1401941052
Total Pages : 289 pages
Book Rating : 4.4/5 (19 download)

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Book Synopsis Crazy Sexy Kitchen by : Kris Carr

Download or read book Crazy Sexy Kitchen written by Kris Carr and published by Hay House, Inc. This book was released on 2014-12-09 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Start eating the crazy, sexy way: a nutrient-dense, plant-happy approach to eating and living that harmonizes your beautiful body at the cellular level! The woman who made prevention hot is now making it delicious! Crazy Sexy Kitchen, the follow-up to Kris Carr’s New York Times bestseller Crazy Sexy Diet, is a Veggie Manifesto for plant-empowered gourmands and novices alike, and it’s filled with inspiration, education, cooking tips, and over 150 nourishing, nosh-worthy recipes. Infused with her signature humor, style, and personal stories, Crazy Sexy Kitchen redefines the kitchen as headquarters for America’s wellness revolution. The goodness born in the Crazy Sexy Kitchen will reach deep into the rest of your life—enriching your health, your home, your heart, and the planet. Crazy Sexy Kitchen gives readers all the tools and know-how needed to adopt a joyful and vibrant Crazy Sexy Diet and Lifestyle. What is the Crazy Sexy Diet and Lifestyle, you ask? A nutrient-dense, plant-happy approach to eating and living that harmonizes your beautiful body at the cellular level. It’s a celebratory way of life that’s deeply connected, healthy, awake and engaged. Now that’s SEXY! Like a long, luxurious meal, Crazy Sexy Kitchen is laid out in courses. You’ll start with a detailed review of the Crazy Sexy Diet. Next you’ll learn how to stock your culinary arsenal. Kris will show you how to find the best kitchen tools and equipment, and prep you with basic culinary skills and lingo. Handy symbols like, gluten-free, soy-free, kid-friendly—and for the time pressed—Crazy Sexy Quickies, help you to easily identify the recipes that are perfect for your dietary needs. Not sure how to put a whole meal together? No problem. Crazy Sexy Kitchen covers that, too—with a hearty dose of menu plans and recipes to inspire and delight. Joined by Whole Foods chef, Chad Sarno, Crazy Sexy Kitchen offers over 150 delicious, nutrient-dense recipes designed to nourish the mind, body, and soul. From juicing to planning a three-course meal, Crazy Sexy Kitchen has all the essentials to fill your kitchen (and life!) with health, happiness, family, friends, and good times.

Pediatric Food Allergy

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Author :
Publisher : Springer Nature
ISBN 13 : 3030332926
Total Pages : 278 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Pediatric Food Allergy by : Ruchi S. Gupta

Download or read book Pediatric Food Allergy written by Ruchi S. Gupta and published by Springer Nature. This book was released on 2020-03-02 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive and practical, this book thoroughly addresses the full range of concerns related to food allergies in the pediatric patient. As food allergies in the pediatric population increase in number and severity, Pediatric Food Allergy: A Clinical Guide provides information on new guidelines and potential treatment options, as well as working to improve awareness, diagnosis, management and prevention practices. Written by experts in their respective fields, chapters are divided into five sections. Opening with an introduction and overview of particular concerns and issues specific to food allergy in the pediatric population, sections two and three address diagnosis and management of comorbid conditions in food allergy, along with development of food allergies and current prevention recommendations. Sections four and five cover food allergy management, prognosis, and therapeutic options with a look to future developments, while all sections include a discussion of epidemiology, differential diagnoses of other potential food-related diseases. In Pediatric Food Allergy: A Clinical Guide, pediatricians and allergists alike will find an invaluable resource as they work with this vulnerable patient population.

The End of Food Allergy

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Author :
Publisher : Penguin
ISBN 13 : 0593189523
Total Pages : 354 pages
Book Rating : 4.5/5 (931 download)

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Book Synopsis The End of Food Allergy by : Kari Nadeau MD, PhD

Download or read book The End of Food Allergy written by Kari Nadeau MD, PhD and published by Penguin. This book was released on 2020-09-29 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: A life-changing, research-based program that will end food allergies in children and adults forever. The problem of food allergy is exploding around us. But this book offers the first glimpse of hope with a powerful message: You can work with your family and your doctor to eliminate your food allergy forever. The trailblazing research of Dr. Kari Nadeau at Stanford University reveals that food allergy is not a life sentence, because the immune system can be retrained. Food allergies--from mild hives to life-threatening airway constriction--can be disrupted, slowed, and stopped. The key is a strategy called immunotherapy (IT)--the controlled, gradual reintroduction of an allergen into the body. With innovations that include state-of-the-art therapies targeting specific components of the immune system, Dr. Nadeau and her team have increased the speed and effectiveness of this treatment to a matter of months. New York Times bestselling author Sloan Barnett, the mother of two children with food allergies, provides a lay perspective that helps make Dr. Nadeau's research accessible for everyone. Together, they walk readers through every aspect of food allergy, including how to find the right treatment and how to manage the ongoing fear of allergens that haunts so many sufferers, to give us a clear, supportive plan to combat a major national and global health issue.