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Nk Cell Subsets In Health And Disease New Developments
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Book Synopsis NK Cell Subsets in Health and Disease: New Developments by : Emanuela Marcenaro
Download or read book NK Cell Subsets in Health and Disease: New Developments written by Emanuela Marcenaro and published by Frontiers Media SA. This book was released on 2017-11-29 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Killer (NK) cells were discovered ca 1975, as the first group of lymphoid cells that were neither T cells nor B cells. Since then, the dissection of the biology of NK cells has been growing exponentially with many seminal discoveries from the identification of MHC class I-specific inhibitory receptors to the discovery of receptor-ligand pairs involved in NK cell activation and to the manipulation of NK cells in cancer. In this research topic, we asked a group of thought leaders in NK cell biology to review recent advances in their origins and biology, and their roles in cancer, infection and inflammation. Together, these 25 articles provide a timely survey of NK cells as critical immunologic components of health and disease. They will hopefully prompt further dialogue and developments in basic and translational immunology.
Book Synopsis NK Cell Subsets in Health and Disease: New Developments by :
Download or read book NK Cell Subsets in Health and Disease: New Developments written by and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Killer (NK) cells were discovered ca 1975, as the first group of lymphoid cells that were neither T cells nor B cells. Since then, the dissection of the biology of NK cells has been growing exponentially with many seminal discoveries from the identification of MHC class I-specific inhibitory receptors to the discovery of receptor-ligand pairs involved in NK cell activation and to the manipulation of NK cells in cancer. In this research topic, we asked a group of thought leaders in NK cell biology to review recent advances in their origins and biology, and their roles in cancer, infection and inflammation. Together, these 25 articles provide a timely survey of NK cells as critical immunologic components of health and disease. They will hopefully prompt further dialogue and developments in basic and translational immunology.
Book Synopsis Natural Killer Cells by : Eric Vivier
Download or read book Natural Killer Cells written by Eric Vivier and published by Springer. This book was released on 2016-02-15 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: To celebrate the 40th anniversary of the discovery of Natural Killer (NK) cells, this volume focuses on the recent advances in our understanding of NK cell development and differentiation and their acquisition of functional properties, as well as the latest models for NK-cell analysis in mice and applications in clinical medicine. NK cells have travelled a circuitous path from their initial description as ‘spontaneous killers’ (for some simply an experimental artifact) to being a bona fide subset of innate lymphoid cells with a complementary mode of action in immune defense and an important mediator of immune reactivity in health and disease. Together, these reviews provide a timely and concise picture of the evolution of NK cells as essential agents in immunity and as potent weapons against disease. This book offers an appealing and insightful resource for scientists and clinicians.
Book Synopsis Natural Killer Cells in Tissue Compartments by : Massimo Vitale
Download or read book Natural Killer Cells in Tissue Compartments written by Massimo Vitale and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: N the last years, our knowledge of human NK cell biology has increased significantly. Several stimulating studies have provided the basis for understanding how NK cells can be "educated" to acquire immunological competence following maturation, or to adapt their function to the environmental changes of "self". New information has been acquired on their lifespan and on the persistence of memory-like NK cell subsets in response to certain viral infections. In addition, the identification and characterization of new markers and the development of more effective analytic approaches have led to the definition of various phenotypically and/or functionally-defined cell subsets. These advances have, in turn, enabled us to study NK cells beyond the peripheral blood, in different tissue compartments including the bone marrow, liver, lungs, skin, intestine and uterus. Recent data indicates that at least part of the tissue NK cell compartment consists of resident cells (which rarely recirculate) characterized by tissue-specific phenotypes and, in some cases, endowed with specialized functions related to the distinct organs in which they reside. These findings stimulate further questions (i) on the origins of these putative tissue-specific NK cell subsets; (ii) on their functional interplay with the local microenvironment; (iii) on their immunological competence and memory capacity and (iv) on their possible specific functional role in healthy and diseased tissues. In this context, the assessment of phenotype, function, maturation, education, differentiation and reprogramming of effector functions in tissue NK cells represents a new stimulating field of investigation that would help to get a more comprehensive picture of NK cell biology. In this Research Topic, we collect articles that highlight the recent advances in our understanding of tissue NK cells and that provide insight into opening new viewpoints on the role of NK cells in both health and disease.
Book Synopsis Natural Killer Cells: Methods and Protocols by : Srinivas S. Somanchi
Download or read book Natural Killer Cells: Methods and Protocols written by Srinivas S. Somanchi and published by Methods in Molecular Biology. This book was released on 2018-05-27 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis New Insights Into B cell Subsets in Health and Disease by : Judith Fraussen
Download or read book New Insights Into B cell Subsets in Health and Disease written by Judith Fraussen and published by Frontiers Media SA. This book was released on 2022-03-04 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis New insights into innate immune cell-based immunotherapies in cancer by : Mary Poupot-Marsan
Download or read book New insights into innate immune cell-based immunotherapies in cancer written by Mary Poupot-Marsan and published by Frontiers Media SA. This book was released on 2024-04-17 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Primary and Secondary Immunodeficiency by : Jonathan A. Bernstein
Download or read book Primary and Secondary Immunodeficiency written by Jonathan A. Bernstein and published by Springer Nature. This book was released on 2021-01-28 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a broad clinical overview of primary and secondary immunodeficiencies nested in clinical cases that will help the reader understand the approach to evaluation, diagnosis, and management of these challenging cases. Chapters begin with a comprehensive overview of immunodeficiencies to ground the reader in practical knowledge of the field and these complex conditions. Chapters cover B lymphocyte immunodeficiency, T cell immunodeficiency, immune dysregulation syndromes, and innate immune defects. They discuss a range of treatment options including gene therapy or bone marrow transplant. The book continues with a discussion on secondary immunodeficiencies and their treatment. Each chapter was written by authors with expertise related to different immunodeficiency disorders and provide a succinct overview of pathomechanisms, diagnosis, and treatment of a specific condition. Primary and Secondary Immunodeficiency will be an excellent resource for practicing allergists, hematologists, clinical immunologists, fellows, residents, and other clinicians who work with immunodeficiency patients.
Book Synopsis Natural Killer Cells in Tissue Compartments by : Massimo Vitale
Download or read book Natural Killer Cells in Tissue Compartments written by Massimo Vitale and published by Frontiers Media SA. This book was released on 2020-03-24 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Immune Tolerance Post Allogeneic Hematopoietic Cell Transplantation by : Dominik Schneidawind
Download or read book Immune Tolerance Post Allogeneic Hematopoietic Cell Transplantation written by Dominik Schneidawind and published by Frontiers Media SA. This book was released on 2020-05-22 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Signaling Mechanisms Regulating T Cell Diversity and Function by : Jonathan Soboloff
Download or read book Signaling Mechanisms Regulating T Cell Diversity and Function written by Jonathan Soboloff and published by CRC Press. This book was released on 2017-03-27 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: T cells play a vital role mediating adaptive immunity, a specific acquired resistance to an infectious agent produced by the introduction of an antigen. There are a variety of T cell types with different functions. They are called T cells, because they are derived from the thymus gland. This volume discusses how T cells are regulated through the operation of signaling mechanisms. Topics covered include positive and negative selection, early events in T cell receptor engagement, and various T cell subsets.
Book Synopsis The RNA Revolution in Embryonic Development and Cell Differentiation in Health and Disease by : Francesco Fazi
Download or read book The RNA Revolution in Embryonic Development and Cell Differentiation in Health and Disease written by Francesco Fazi and published by Frontiers Media SA. This book was released on 2021-11-02 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Regulation of Inflammatory Signaling in Health and Disease by : Dakang Xu
Download or read book Regulation of Inflammatory Signaling in Health and Disease written by Dakang Xu and published by Springer. This book was released on 2018-12-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses recent research in innate immunity, which has revealed a large number of receptors that sense the presence of microorganisms or cellular damage in tissues. In complex tissues, many of these sensing events occur simultaneously. Thus, the downstream signaling pathways need to be integrated so that an appropriate cellular inflammatory response can be initiated. In addition, the inflammasome defines the molecular and cellular processes of inflammation in response to microbial infection. Previous data suggested that regulation of inflammasomes is mediated by microbes, but inflammasomes also have antimicrobial functions. Increasing evidence in mouse models, together with human data, strongly implicates an involvement of the inflammasome and uncontrolled inflammation in the initiation and progression of diseases with a high impact on public health. The book reviews novel aspects of functional genomics, epigenomics, transcriptomics, post-translat ional modifications, microbiome and immunometabolism in order to understand inflammatory signaling and responses, covering recent findings on the mechanisms underlying the regulation of inflammatory responses to pathogens, dysregulation of these responses in inflammatory disease, and the use of such mechanisms to boost or subdue the inflammatory response. Bridging the gaps in understanding between the fields of human and mouse immunology, it provides valuable insights into inflammatory-mediated disease and immune defense. Such innovative perspectives in both basic and clinical research promote the translation of knowledge to the clinic.
Book Synopsis The Role of Immune Cells in Hepatic Ischemia Reperfusion by : Tao Qiu
Download or read book The Role of Immune Cells in Hepatic Ischemia Reperfusion written by Tao Qiu and published by Frontiers Media SA. This book was released on 2022-12-01 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Role of Metabolism in Regulating Immune Cell Fate Decisions by : Anna Ohradanova-Repic
Download or read book Role of Metabolism in Regulating Immune Cell Fate Decisions written by Anna Ohradanova-Repic and published by Frontiers Media SA. This book was released on 2020-05-26 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS). We hereby state publicly that the IUIS has had no editorial input in articles included in this Research Topic, thus ensuring that all aspects of this Research Topic are evaluated objectively, unbiased by any specific policy or opinion of the IUIS.
Book Synopsis Principles and Practice of Transplant Infectious Diseases by : Amar Safdar
Download or read book Principles and Practice of Transplant Infectious Diseases written by Amar Safdar and published by Springer. This book was released on 2019-06-13 with total page 1173 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive volume provides a platform from which both major and minor infectious diseases related issues are addressed in-depth among this highly susceptible population. The book begins with an overview of infections in various modalities. This is followed by chapters on clinical disorders, etiologic agents, therapeutics, and infection prevention. Chapters include easy-to-follow figures and tables, radiologic images, and pictorial demonstrations of various disease states to familiarize and reacquaint the transplant clinicians and surgeons in practice and training, and those belonging to subspecialties providing supportive care for these patients. Discussions to enumerate the noninfectious causes that mimic infectious diseases; clinical relevance and effective utility of existing and emerging diagnostic tools are presented throughout the book. Authored by leaders in their fields, this book is the go-to reference for management of patients undergoing hematopoietic and solid organ transplantation.
Book Synopsis Innate Immunity in Health and Disease by : Shailendra K. Saxena
Download or read book Innate Immunity in Health and Disease written by Shailendra K. Saxena and published by BoD – Books on Demand. This book was released on 2021-08-25 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book focuses on various aspects and properties of innate immunity, whose deep understanding is integral for safeguarding the human race from further loss of resources and economies due to innate immune response-mediated diseases. Throughout this book, we examine the individual mechanisms by which the innate immune response acts to protect the host from pathogenic infectious agents and other non-communicable diseases. Written by experts in the field, the volume discusses the significance of macrophages in infectious disease, tumor metabolism, and muscular disorders. Chapters cover such topics as the fate of differentiated macrophages and the molecular pathways that are important for the pathologic role of macrophages.
