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Author : P. G. Hugenholtz
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110870568
Total Pages : 108 pages
Book Rating : 4.1/5 (18 download)
Download or read book Nitroglycerin 7 written by P. G. Hugenholtz and published by Walter de Gruyter GmbH & Co KG. This book was released on 2019-07-08 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "Nitroglycerin 7".
Author : Paul G. Hugenholtz
Publisher :
ISBN 13 : 9783110133967
Total Pages : 103 pages
Book Rating : 4.1/5 (339 download)
Download or read book Nitroglycerin written by Paul G. Hugenholtz and published by . This book was released on 1991 with total page 103 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : P. Needleman
Publisher : Springer Science & Business Media
ISBN 13 : 364266024X
Total Pages : 206 pages
Book Rating : 4.6/5 (426 download)
Download or read book Organic Nitrates written by P. Needleman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitroglycerin and other organic nitrates have been used for over a century in the treatment of angina pectoris. Millions of patients, throughout the world, have placed nitroglycerin tablets under the tongue and have experienced rapid and dramatic relief from the chest pain that frequently occurs as a manifestation of disease of the coronary arteries. The empirical observation of the safe use of nitrates for tile alleviation of the symptoms of angina have led to their widespread medical acceptance. The use of organic nitrates preceded any knowledge of their mechanism of action or their ultimate metabolic fate. Thus, more simply stated, although sub lingual nitrates helped the patients, little was known concerning what these drugs do to the body or what the body does to the drugs. A substantial number of investigators have focused on these questions especially during the last two decades. We now have considerably more insight into the pathways of degradation of organic nitrates and the relationship of the metabolic processes to the biological action of these agents. Similarly, considerable effort has been expended in understanding the mechanism of action of these agents directly on vascular smooth muscle and on cardiac work and performance. Finally, there is a more substantive understanding of the physiology of the coronary circulation as well as the" pathophysiologic manifestations of myocardial disease.
Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 030915698X
Total Pages : 304 pages
Book Rating : 4.3/5 (91 download)
Download or read book Cardiovascular Disability written by Institute of Medicine and published by National Academies Press. This book was released on 2010-12-04 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Social Security Administration (SSA) uses a screening tool called the Listing of Impairments to identify claimants who are so severely impaired that they cannot work at all and thus immediately qualify for benefits. In this report, the IOM makes several recommendations for improving SSA's capacity to determine disability benefits more quickly and efficiently using the Listings.
Author : U.S. Department of Transportation
Publisher : Simon and Schuster
ISBN 13 : 1626363765
Total Pages : 400 pages
Book Rating : 4.6/5 (263 download)
Download or read book Emergency Response Guidebook written by U.S. Department of Transportation and published by Simon and Schuster. This book was released on 2013-06-03 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Does the identification number 60 indicate a toxic substance or a flammable solid, in the molten state at an elevated temperature? Does the identification number 1035 indicate ethane or butane? What is the difference between natural gas transmission pipelines and natural gas distribution pipelines? If you came upon an overturned truck on the highway that was leaking, would you be able to identify if it was hazardous and know what steps to take? Questions like these and more are answered in the Emergency Response Guidebook. Learn how to identify symbols for and vehicles carrying toxic, flammable, explosive, radioactive, or otherwise harmful substances and how to respond once an incident involving those substances has been identified. Always be prepared in situations that are unfamiliar and dangerous and know how to rectify them. Keeping this guide around at all times will ensure that, if you were to come upon a transportation situation involving hazardous substances or dangerous goods, you will be able to help keep others and yourself out of danger. With color-coded pages for quick and easy reference, this is the official manual used by first responders in the United States and Canada for transportation incidents involving dangerous goods or hazardous materials.
Author : Subrata Bhadra
Publisher : GRIN Verlag
ISBN 13 : 3656475849
Total Pages : 135 pages
Book Rating : 4.6/5 (564 download)
Download or read book Nitroglycerin Sustained Release Tablet. Formulation Design and Evaluation written by Subrata Bhadra and published by GRIN Verlag. This book was released on 2013-08-07 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: Master's Thesis from the year 2010 in the subject Medicine - Pharmacology, Pharmacy, University of Dhaka (M. Pharm, in Pharmaceutical Technology), language: English, abstract: The aim of the present studies was to develop and characterize 2.6 mg sustained release matrix tablets of Nitroglycerin. Tablets were prepared by direct compression method. Methocel K15M CR and Methocel K100LV CR polymers were used as rate retarding agents in nine formulations (F-1 to F-9). The granules were evaluated for angle of repose, loose bulk density, tapped bulk density, Carr’s index, Hausner ratio, moisture content, total porosity and assay. The tablets were subjected to diameter, thickness, assay, uniformity of content, assay after 1Month at 40°C+75%RH, hardness, friability, and in vitro dissolution studies. The granules showed satisfactory flow properties, compressibility, and drug content. All the tablet formulations showed acceptable pharmacotechnical properties and complied with pharmacopoeial specifications for tested parameters. The in vitro dissolution study was carried out for 8 hour using USP-2009 Apparatus-I (Rotating basket method) in distilled water as the dissolution medium. The release mechanisms were explored and explained by Zero order, First order, Higuchi, Korsmeyer-Peppas and Hixson-Crowell equations. Nine formulations were prepared by using three variable ratio of two polymers; Methocel K15M CR (25%, 20% and 15%) and Methocel K100LV CR (15%, 10% and 5%) where all the formulations (F-1 to F-9) contained 0.5% colloidal silicon dioxide and 1% magnesium stearate. Among these nine formulations, six formulations; F-2 (Methocel K15M CR: Methocel K100LV CR = 25% : 10%), F-3 (Methocel K15M CR : Methocel K100LV CR = 25% : 5%), F-4 (Methocel K15M CR : Methocel K100LV CR = 20% : 15%) F-5 (Methocel K15M CR: Methocel K100LV CR = 20% : 10%), F-6 (Methocel K15M CR : Methocel K100LV CR = 20% : 5%) and F-7 (Methocel K15M CR : Methocel K100LV CR = 15% : 15%) met the official specification of release profile. It was also found that the type and the amount of polymers significantly affect the time required for 50% (T50% or MDT) of drug release, release rate constant and diffusion exponent. Higher the MDT value indicates a higher drug retaining capacity of the polymers and vice-versa. Kinetic modeling of in vitro dissolution profiles revealed the drug release mechanism of all proposed formulations followed anomalous type or non-Fickian transport (n>0.43 and n
Author :
Publisher :
ISBN 13 :
Total Pages : 988 pages
Book Rating : 4.:/5 (318 download)
Download or read book Decennial Index to Chemical Abstracts written by and published by . This book was released on 1916 with total page 988 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 840 pages
Book Rating : 4.3/5 (243 download)
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1978 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Thomas Edward Thorpe
Publisher :
ISBN 13 :
Total Pages : 768 pages
Book Rating : 4.:/5 (5 download)
Download or read book A Dictionary of Applied Chemistry written by Thomas Edward Thorpe and published by . This book was released on 1922 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : P. Lichtlen
Publisher : Springer Science & Business Media
ISBN 13 : 3642680852
Total Pages : 713 pages
Book Rating : 4.6/5 (426 download)
Download or read book Nitrates III written by P. Lichtlen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacological and clinical research on nitrates continues to be of growing interest in many centers. This is surprising in view of the fact that their favorable effects in angina pectoris were described by Brunton and by Murrell in the Lancet more than 100 years ago. As expected, a host of new information has been collected since the two previous symposia on nitrates held in Stockholm in 1975 and Berlin in 1978. New insights were gained into the pharmacology, pharmacokinetics and pharmacodynamics of nitrates, as well as into their clinical effects in acute and chronic ischemic heart diseases and in severe congestive heart failure. Relatively little progress, however, was observed in research into the basic action of nitrates. Although most investigators agree that intracellular sequestration of calcium is probably the main mechanism by which nitrates lead to the reduction of vascular smooth muscle tone, the exact site of their action still remains undefined. In contrast, dose-dependent differences in venous and arteriolar tone have long been clearly established. Treatment was again in the main stream of discussion. The question of tolerance following long-term administration was discussed in depth and the term "pseudotolerance" was introduced to describe the adaptation of the body's circulatory system to chronic vasodilation. This is especially important in long term prophylactic antiischemic treatment in stable, as well as in unstable angina pectoris (i.e. during increased vasomotor tone - spasm).
Author : United States. Environmental Protection Agency. Office of Toxic Substances
Publisher :
ISBN 13 :
Total Pages : 808 pages
Book Rating : 4.3/5 (243 download)
Download or read book User guide and indices to the initital inventory, substance name index written by United States. Environmental Protection Agency. Office of Toxic Substances and published by . This book was released on 1979 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Edward Thorpe
Publisher :
ISBN 13 :
Total Pages : 804 pages
Book Rating : 4.5/5 (32 download)
Download or read book A Dictionary of Applied Chemistry written by Edward Thorpe and published by . This book was released on 1912 with total page 804 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 400 pages
Book Rating : 4.X/5 (4 download)
Download or read book Military Explosives written by and published by . This book was released on 1989 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Donald L. Wise
Publisher : CRC Press
ISBN 13 : 9780824703691
Total Pages : 908 pages
Book Rating : 4.7/5 (36 download)
Download or read book Handbook of Pharmaceutical Controlled Release Technology written by Donald L. Wise and published by CRC Press. This book was released on 2000-08-24 with total page 908 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Pharmaceutical Controlled Release Technology reviews the design, fabrication, methodology, administration, and classifications of various drug delivery systems, including matrices, and membrane controlled reservoir, bioerodible, and pendant chain systems. Contains cutting-edge research on the controlled delivery of biomolecules! Discussing the advantages and limitations of controlled release systems, the Handbook of Pharmaceutical Controlled Release Technology covers oral, transdermal, parenteral, and implantable delivery of drugs discusses modification methods to achieve desired release kinetics highlights constraints of system design for practical clinical application analyzes diffusion equations and mathematical modeling considers environmental acceptance and tissue compatibility of biopolymeric systems for biologically active agents evaluates polymers as drug delivery carriers describes peptide, protein, micro-, and nanoparticulate release systems examines the cost, comfort, disease control, side effects, and patient compliance of numerous delivery systems and devices and more!
Author : Halbert Powers Gillette
Publisher :
ISBN 13 :
Total Pages : 864 pages
Book Rating : 4.:/5 (321 download)
Download or read book Handbook of Rock Excavation, Methods and Cost written by Halbert Powers Gillette and published by . This book was released on 1916 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Society of Chemical Industry (Great Britain)
Publisher :
ISBN 13 :
Total Pages : 1456 pages
Book Rating : 4.U/5 (183 download)
Download or read book Journal of the Society of Chemical Industry written by Society of Chemical Industry (Great Britain) and published by . This book was released on 1913 with total page 1456 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 774 pages
Book Rating : 4.:/5 (334 download)
Download or read book Journal of the Society of Chemical Industry written by and published by . This book was released on 1904 with total page 774 pages. Available in PDF, EPUB and Kindle. Book excerpt:
