The Endothelium

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Author :
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615041230
Total Pages : 309 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis The Endothelium by : Michel Félétou

Download or read book The Endothelium written by Michel Félétou and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References

Oxidants in Biology

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1402083998
Total Pages : 324 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Oxidants in Biology by : Giuseppe Valacchi

Download or read book Oxidants in Biology written by Giuseppe Valacchi and published by Springer Science & Business Media. This book was released on 2008-06-06 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidants, like other aspects of life, involves tradeoffs. Oxidants, whether intentionally produced or by-products of normal metabolism can either mediate a variety of critical biological processes but when present inappropriately cause extensive damage to biological molecules (DNA, proteins, and lipids). These effects can lead to either damage that is a major contributor to aging and degenerative diseases (or to other diseases such as cancer, cardiovascular disease, immune-system decline, brain dysfunction, and cataracts) or normal physiological function- tissue repair, defense against pathogens and cellular proliferation. On the other hand the body is equipped with a complex antioxidant/oxidant handling system which includes both enzymatic and nonenzymatic (i.e. small molecules such as flavonoids, ascorbate, tocopherol, and carotenoids) produced endogenously or derived from the diet. This book focuses on how the same molecules can have favorable or noxious effects depending on location, level and timing. Each chapter focuses on one particular molecule or oxidant/antioxidant system and provides a state of the art review of the current understanding regarding both positive and negative actions of the system under review.

Brenner and Rector's The Kidney E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 1455723045
Total Pages : 3066 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Brenner and Rector's The Kidney E-Book by : Maarten W. Taal

Download or read book Brenner and Rector's The Kidney E-Book written by Maarten W. Taal and published by Elsevier Health Sciences. This book was released on 2011-11-01 with total page 3066 pages. Available in PDF, EPUB and Kindle. Book excerpt: Overcome the toughest clinical challenges in nephrology with the new 9th edition of Brenner/Rector’s The Kidney! A brand-new editorial team of Drs. Maarten W. Taal, Glenn M. Chertow, Philip A. Marsden, Karl Skorecki, Alan S. L. Yu, and Barry M. Brenner,, together with a diverse list of international contributors bring you the latest knowledge and best practices on every front in nephrology worldwide. Brand-new sections on Global Considerations in Nephrology and Pediatric Nephrology, as well as new chapters on recent clinical trials, cardiovascular and renal risk prediction in chronic kidney disease, identification of genetic causes of kidney disease, and many others, keep you at the forefront of this rapidly growing, ever-changing specialty. Brenner/Rector remains the go-to resource for practicing and training nephrologists and internists who wish to master basic science, pathophysiology, and clinical best practices. Broaden your knowledge base with expert, dependable, comprehensive answers for every stage of your career from the most comprehensive, definitive clinical reference in the field! Prepare for certification or recertification with a review of the basic science that underpins clinical nephrology as well as a comprehensive selection of the most important bibliographical sources in nephrology. Visually grasp and better understand critical information with the aid of over 700 full-color high-quality photographs as well as carefully chosen figures, algorithms, and tables to illustrate essential concepts, nuances of clinical presentation and technique, and decision making. Get internationally diverse, trusted guidance and perspectives from a team of well-respected global contributors, all of whom are at the top and the cutting edge of your field. A new editorial team headed by Dr. Taal and hand-picked by Dr. Brenner ensures the ongoing adherence to previous standards of excellence. Access information quickly thanks to a new, reorganized format and supplemental figures, tables, additional references, and expanded discussions. Keep current with the rapid development of care and research worldwide. A new section, "Global Considerations", focuses on regions outside Europe and North America. Leading experts from Latin America, Africa, Near and Middle East, Indian Subcontinent, Far East, Oceania and Australia present their expert insights into specific conditions, as well as progress and challenges in the development of the specialty. Improve therapy and outcomes for children with renal disease. New to this edition, "Pediatric Nephrology" addresses renal pathologies that usually present in childhood and covers topics such as Maturation of Kidney Structure and Function; Fluid; Electrolyte and Acid-Base Disorders in Children; Diseases of the Kidney and Urinary Tract in Children; Dialysis in Children; and Kidney Transplantation in Children. Stay up to date with all the latest clinical information including recent clinical trials, genetic causes of kidney disease, and cardiovascular and renal risk prediction in chronic kidney disease.

Brenner and Rector's The Kidney E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323262597
Total Pages : 3585 pages
Book Rating : 4.3/5 (232 download)

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Book Synopsis Brenner and Rector's The Kidney E-Book by : Alan S. L. Yu

Download or read book Brenner and Rector's The Kidney E-Book written by Alan S. L. Yu and published by Elsevier Health Sciences. This book was released on 2015-10-25 with total page 3585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Overcome the toughest clinical challenges in nephrology with Brenner & Rector’s The Kidney -- the most well-known nephrology resource in the world. A diverse team of more than 200 international contributors brings you the latest knowledge and best practices on every front in nephrology worldwide. From basic science and pathophysiology to clinical best practices, Brenner & Rector’s The Kidney is your go-to resource for any stage of your career. Review of the basic science that underpins clinical nephrology, comprehensive selection of the most important bibliographical sources in nephrology, and Board Review-style questions help you prepare for certification or recertification. Coverage of kidney health and disease from pre-conception through fetal and infant health, childhood, adulthood, and into old age. Expanded sections and chapter on global perspective and ethical considerations. Uniform terminology and nomenclature in line with emerging consensus in world kidney community. More than 700 full-color high-quality photographs as well as carefully chosen figures, algorithms, and tables to illustrate essential concepts, nuances of clinical presentation and technique, and decision making provide a visual grasp and better understanding of critical information. Internationally diverse, trusted guidance and perspectives from a team of well-respected global contributors . An editorial team headed by Dr. Skorecki and handpicked by Dr. Brenner ensures the ongoing adherence to previous standards of excellence. All chapters have been extensively updated or entirely rewritten by authorities in their respective fields. The latest clinical information including recent clinical trials, genetic causes of kidney disease, cardiovascular and renal risk prediction in chronic kidney disease, new paradigms in fluid and electrolyte management, and pediatric kidney disease, keep you current with the rapid development of care and research worldwide.

Nitric Oxide

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642570771
Total Pages : 676 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Nitric Oxide by : B. Mayer

Download or read book Nitric Oxide written by B. Mayer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 676 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitric oxide (NO) has been discovered to play a fundamental role in a number of biological phenomena. This book describes various aspects of nitric oxide biology, physiology and pharmacology. It is divided into three sections. The first part deals with the basic chemistry and enzymology of NO, thus laying a molecular basis for what follows. The middle part surveys the physiological roles of NO under normal conditions. The concluding part explores the relevance of NO to disease, both as a pathogenic factor and a therapeutic target. The book thus provides detailed information on NO biology to the reader unfamiliar with the field and represents a reference work for scientists working in an NO-related field of biomedical research. Each chapter, written by experts in their fields, gives a broad introduction followed by a comprehensive review of the current knowledge and a detailed reference list.

Primer on Kidney Diseases E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 1437721109
Total Pages : 613 pages
Book Rating : 4.4/5 (377 download)

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Book Synopsis Primer on Kidney Diseases E-Book by : Arthur Greenberg

Download or read book Primer on Kidney Diseases E-Book written by Arthur Greenberg and published by Elsevier Health Sciences. This book was released on 2009-02-18 with total page 613 pages. Available in PDF, EPUB and Kindle. Book excerpt: This official publication of the National Kidney Foundation (NKF) covers all aspects of adult and pediatric kidney diseases and is ideal for nephrologists and non-nephrologists alike. The full-color design, high-quality photographs, and outstanding graphs and tables make information easy to access and understand. The latest management techniques and pearls from leading clinical experts—including international contributors—offer practical and authoritative guidance. Edited by Dr. Arthur Greenberg and members of the NKF Scientific Advisory Board, this state-of-the-art primer provides consistent depth of coverage, balanced discussion of controversy, and a uniform focus of information. Incorporates the latest NKF Kidney/Outcome Quality Initiative (K/DOQI) guidelines on chronic kidney disease staging and management. Features a current and practical review of the anatomy, physiology, pathophysiology, diagnosis, and management of kidney disease, fluid and electrolyte disorders, hypertension, dialysis, and renal transplantation. Covers the whole field of nephrology in concise and well-illustrated, four-color chapters. Puts complex material and the latest developments into perspective for in-depth, yet succinct summaries in every area. Includes high-quality photographs, as well as outstanding graphs and tables for a varied approach to the subject matter. new chapters on Disorders of Magnesium Homeostasis and Thombotic Microangiopathies to reflect advances in management. Includes the most up-to-date management guidelines and pearls of wisdom to provide you with best practices. Presents new ideas and perspectives through 25% new contributing clinical experts.

Free Radicals, Nitric Oxide, and Inflammation

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Author :
Publisher : IOS Press
ISBN 13 : 9781586032432
Total Pages : 268 pages
Book Rating : 4.0/5 (324 download)

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Book Synopsis Free Radicals, Nitric Oxide, and Inflammation by : Tomris Özben

Download or read book Free Radicals, Nitric Oxide, and Inflammation written by Tomris Özben and published by IOS Press. This book was released on 2003 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Renal Failure

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9535106309
Total Pages : 286 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Renal Failure by : Momir Polenakovic

Download or read book Renal Failure written by Momir Polenakovic and published by BoD – Books on Demand. This book was released on 2012-05-23 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book "Renal Failure - The Facts" consists of some facts about diagnosis, etiopathogenis and treatment of acute and chronic renal failure. Acute, as well as chronic renal failure is great medical problems and their treatment is a burden for the budget of each government. The purpose of the chapters is to present some important issues of diagnosis and causes of AKI, as well as caused by snakes and arthropods, after cardiac surgery, as well as some therapeutic achievements in AKI. Well presented are the psychological condition in patients on haemodialysis, as well as the treatment of diabetic uremics. The book is aimed at clinicians with a special interest in nephrology, but it should also prove to be a valuable resource for any generalists who encounter a nephrological problems in their day-to-day practice.

Index Medicus

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Author :
Publisher :
ISBN 13 :
Total Pages : 2432 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Index Medicus by :

Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Nitric Oxide and Inflammation

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Author :
Publisher : Springer
ISBN 13 : 3034882416
Total Pages : 308 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Nitric Oxide and Inflammation by : Daniela Salvemini

Download or read book Nitric Oxide and Inflammation written by Daniela Salvemini and published by Springer. This book was released on 2013-03-11 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Literally thousands of papers have been published on nitric oxide over the past ten years. But there is no single monograph available that has previously attempted to summarize the important features of the roles of nitric oxide in inflammation. The voluminous literature regarding the incredible range of chemical and biological effects of nitric oxide and reactive nitrogen oxide species, RNOS, may present a tangle of confusing information to the researcher. This volume brings together experts from nitric oxide and inflammation research and presents a concise up-to-date overview as well as future aspects of this rapidly growing field.

Critical Care Nephrology

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 1416042520
Total Pages : 1851 pages
Book Rating : 4.4/5 (16 download)

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Book Synopsis Critical Care Nephrology by : Claudio Ronco

Download or read book Critical Care Nephrology written by Claudio Ronco and published by Elsevier Health Sciences. This book was released on 2009-01-01 with total page 1851 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This 2nd edition of Critical care nephrology continues to provide comprehensive coverage of the latest advances in critical care procedures for the adult or pediatric patient with renal diseases or disorders. It presents a common language and standardized guidelines to help multi-disciplinary physicians caring for the critically ill communicate more effectively. "--BOOK JACKET.

Nitric Oxide

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Author :
Publisher : Academic Press
ISBN 13 : 0080920446
Total Pages : 852 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Nitric Oxide by : Louis J. Ignarro

Download or read book Nitric Oxide written by Louis J. Ignarro and published by Academic Press. This book was released on 2009-11-05 with total page 852 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitric oxide (NO) is a gas naturally found in the body that conveys information between cells. In the last decade researchers have found that NO is a signaling molecule of key importance for the cardiovascular system, regulating blood pressure and blood flow to different organs. In addition, discoveries surrounding nitric oxide's role as a principal neurotransmitter moderating erectile function, a pathophysiological negotiator and messenger in inflammation, and a weapon against infections have increased research attention across the fields of biochemistry, chemistry, molecular biology, gene therapy, cell biology, immunology, pharmacology, neuroscience, and physiology. - Edited by Nobel Laureate Louis J. Ignarro - Up-to-date therapeutic implications of nitric oxide research - Authored by world experts on nitric oxide - Detailed research of the biochemistry and synthesis of nitric oxide

Chronic Renal Disease

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Author :
Publisher : Academic Press
ISBN 13 : 0128158778
Total Pages : 1392 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Chronic Renal Disease by : Paul L. Kimmel

Download or read book Chronic Renal Disease written by Paul L. Kimmel and published by Academic Press. This book was released on 2019-08-28 with total page 1392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic Renal Disease, Second Edition, comprehensively investigates the physiology, pathophysiology, treatment and management of chronic kidney disease (CKD). This translational reference takes an in-depth look at CKD with no coverage of dialysis or transplantation. Chapters are devoted to the scientific investigation of chronic kidney disease, the most common problems faced by nephrologists in the management of chronic kidney disease, specific illnesses in the CKD framework, and how the management of CKD in a polycystic kidney disease patient differs from other CKD patients. This award-winning reference features a series of case studies, covering both clinical aspects and pathophysiology. Questions are open ended, progressively more difficult, and repetitive across different patient clinical problems and different chapters. The cases and questions included will be useful for medical students, residency board reviews, and clinician teaching or conference preparation. - Includes case studies and questions which can be used as a teaching tool for medical students and resident - Provides coverage of classification and measurement, epidemiology, pathophysiology, complications of CKD, fluid/electrolyte disorders in CKD, CKD and systemic illnesses, clinical considerations, therapeutic considerations, and special considerations

Studies of Epithelial Transporters and Ion Channels

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Author :
Publisher : Springer Nature
ISBN 13 : 3030554546
Total Pages : 1247 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Studies of Epithelial Transporters and Ion Channels by : Kirk L. Hamilton

Download or read book Studies of Epithelial Transporters and Ion Channels written by Kirk L. Hamilton and published by Springer Nature. This book was released on 2021-03-04 with total page 1247 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses unique ion channels and transporters that are located within epithelial tissues of various organs including the kidney, intestine, pancreas and respiratory tract. The authors will show, that each of these channels and transporters play crucial roles in transepithelial ion and fluid transport across epithelia and their responsibility in maintaining homeostasis. The reader gains an understanding of the fundamentals of epithelial ion transport, in terms of function, modelling, regulation, trafficking, structure and pharmacology. This is the third of three volumes highlighting the importance of epithelial ion channels and transporters in basic physiology and pathophysiology of human diseases. The focus of this volume lies with different ion channel and transporter families. Additionally, this volume benefits from pharmaceutical contributors and their insights into recent pre-clinical drug discovery efforts and results from clinical trials. Overall, these chapters offer a more thorough coverage of individual epithelial ion channels and transporters from the 1st Edition, along with eleven new chapters. That makes Volume 3 an insightful contribution for physiology students, scientists and clinicians.

Cumulated Index Medicus

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Author :
Publisher :
ISBN 13 :
Total Pages : 1860 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1999 with total page 1860 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Campbell-Walsh Urology

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Publisher : Elsevier Health Sciences
ISBN 13 : 1416069119
Total Pages : 2952 pages
Book Rating : 4.4/5 (16 download)

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Book Synopsis Campbell-Walsh Urology by : Alan J. Wein

Download or read book Campbell-Walsh Urology written by Alan J. Wein and published by Elsevier Health Sciences. This book was released on 2011-08-25 with total page 2952 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since 1954, Campbell-Walsh Urology has been internationally recognized as the pre-eminent text in its field. Edited by Alan J. Wein, MD, PhD(hon), Louis R. Kavoussi, MD, Alan W. Partin, MD, PhD, Craig A. Peters, MD, FACS, FAAP, and the late Andrew C. Novick, MD, it provides you with everything you need to know at every stage of your career, covering the entire breadth and depth of urology - from anatomy and physiology through the latest diagnostic approaches and medical and surgical treatments. Be certain with expert, dependable, accurate answers for every stage of your career from the most comprehensive, definitive text in the field! Required reading for all urology residents, Campbell-Walsh Urology is the predominant reference used by The American Board of Urology for its board examination questions. Visually grasp and better understand critical information with the aid of algorithms, photographs, radiographs, and line drawings to illustrate essential concepts, nuances of clinical presentation and technique, and decision making. Stay on the cutting edge with online updates. Get trusted perspectives and insights from hundreds of well-respected global contributors, all of whom are at the top and the cutting edge of their respective fields. Stay current with the latest knowledge and practices. Brand-new chapters and comprehensive updates throughout include new information on perioperative care in adults and children, premature ejaculation, retroperitoneal tumors, nocturia, and more! Meticulously revised chapters cover the most recent advancements in robotic and laparoscopic bladder surgery, open surgery of the kidney, management of metastic and invasive bladder cancer, and many other hot topics!Reference information quickly thanks to a new, streamlined print format and easily searchable online access to supplemental figures, tables, additional references, and expanded discussions as well as procedural videos and more at www.expertconsult.com. The new edition of Campbell-Walsh Urology is the must have reference for practitioners and residents!

Nitric Oxide Synthase

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 953513163X
Total Pages : 250 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Nitric Oxide Synthase by : Seyed Soheil Saeedi Saravi

Download or read book Nitric Oxide Synthase written by Seyed Soheil Saeedi Saravi and published by BoD – Books on Demand. This book was released on 2017-05-17 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitric Oxide Synthase - Simple Enzyme-Complex Roles provides information on nitric oxide synthase, a biomolecule of key importance for the different biological systems, including central and peripheral nervous, cardiovascular, and reproductive systems. With recent links to the role of nitric oxide in the reactions that can impact cell signaling, and discoveries surrounding the complex role of nitric oxide synthase that have increased research attention across the fields of cell and molecular biology, physiology, pharmacology, toxicology, neuroscience, cardiology, urology, and endocrinology, this book tries to provide a comprehensive overview of biology/pathobiology of nitric oxide synthases and a perspective from possible therapeutic indication of the enzyme inhibitors.