Nitric Oxide, Cytochromes P450, and Sexual Steroid Hormones

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Publisher : Springer Science & Business Media
ISBN 13 : 3662035030
Total Pages : 351 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Nitric Oxide, Cytochromes P450, and Sexual Steroid Hormones by : Jack R. Jr. Lancaster

Download or read book Nitric Oxide, Cytochromes P450, and Sexual Steroid Hormones written by Jack R. Jr. Lancaster and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of mammalian nitric oxide (NO) synthesis from L-arginine has led to a profound increase in our understanding of basic physiological and pathophysiological processes. The NO-dependent regulation of steroidogenic cytochromes P450, such as aromotase, and local, tissue-specific regulation of NOS isoform expression by sexual steroid hormones, such as estrogen and progesterone, promises to provide new insights into the regulation of endocrinological processes. Research on the interaction between the NO and sexual steroid systems are likely to lead to novel therapeutic concepts for use in diseases associated with perturbations of the endocrine system.

Nitric Oxide in Bone and Joint Disease

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Publisher : Cambridge University Press
ISBN 13 : 9780521592208
Total Pages : 216 pages
Book Rating : 4.5/5 (922 download)

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Book Synopsis Nitric Oxide in Bone and Joint Disease by : Mika V. J. Hukkanen

Download or read book Nitric Oxide in Bone and Joint Disease written by Mika V. J. Hukkanen and published by Cambridge University Press. This book was released on 1998-10-15 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitric oxide research has emerged as one of the most important areas in bone and joint diseases. First published in 1998, this book draws together knowledge on the actions of this mediator and its role in such common diseases as arthritis and osteoporosis. It introduces the basic biology and biochemistry of nitric oxide, the immune response and bone biology. It reviews in depth the facts we know today and the future promise of this exciting area of research. The book will give scientists and clinicians a unique insight into this increasingly important area. It also emphasises potential treatments which exploit our understanding of the role of nitric oxide in bone and joint disease.

Signal Transduction and the Gasotransmitters

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Publisher : Springer Science & Business Media
ISBN 13 : 1592598064
Total Pages : 372 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Signal Transduction and the Gasotransmitters by : Rui Wang

Download or read book Signal Transduction and the Gasotransmitters written by Rui Wang and published by Springer Science & Business Media. This book was released on 2004-06-11 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gasotransmitters-principally nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)-are endogenous signaling molecules that play a significant role in the biomedical, clinical, and health sciences, as well as in population health studies. In Signal Transduction and the Gasotransmitters: NO, CO, and H2S in Biology and Medicine, a panel of distinguished researchers and clinicians review the biological and biomedical aspects of gasotransmitters, emphasizing their signaling transduction mechanisms in general, and ion channel regulation in particular. The authors discuss the endogeneous metabolism and regulation of gasotransmitters, their toxicological profiles and biological actions, and their interactions in terms of their production and effects. The physiological roles of NO, CO, and H2S in the regulation of the cardiovascular, neuronal, and gastrointestinal systems, as well as of cell metabolism, are also reviewed, along with the interaction of the gastrotransmitters with KATP,KCa voltage-gated Ca2+, voltage-gated Na+, and cyclic nucleotide-gated ion channels. Included in the array of different mechanisms for the interaction of NO, CO, and H2S are channel phosphorylation, S-nitrosylation, carboxylation, sulfuration, and altered cellular redox status. The authors also offer guidance and suggestions for exploring and further characterizing other still unknown gasotransmitters. Authoritative and comprehensive, Signal Transduction and the Gasotransmitters: NO, CO, and H2S in Biology and Medicine offers clinical scientists and physicians not only a deeper understanding, but also a cutting-edge review, of the critically important field of gasotransmitter biology and medicine.

Textbook of Biochemistry with Clinical Correlations

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Publisher : John Wiley & Sons
ISBN 13 : 0470281731
Total Pages : 1260 pages
Book Rating : 4.4/5 (72 download)

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Book Synopsis Textbook of Biochemistry with Clinical Correlations by : Thomas M. Devlin

Download or read book Textbook of Biochemistry with Clinical Correlations written by Thomas M. Devlin and published by John Wiley & Sons. This book was released on 2010-01-19 with total page 1260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a clear and precise discussion of the biochemistry of eukaryotic cells, particularly those of mammalian tissues, relates biochemical events at a cellular level to the subsequent physiological processes in the whole animal, and cites examples of abnormal biochemical processes in human disease. The organization and content are tied together to provide students with the complete picture of biochemistry and how it relates to human diseases.

Omega-3 Fatty Acids

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Publisher : Humana Press
ISBN 13 : 331940458X
Total Pages : 611 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Omega-3 Fatty Acids by : Mahabaleshwar V. Hegde

Download or read book Omega-3 Fatty Acids written by Mahabaleshwar V. Hegde and published by Humana Press. This book was released on 2016-09-15 with total page 611 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume argues for the importance of essential nutrients in our diet. Over the last two decades there has been an explosion of research on the relationship of Omega-3 fatty acids and the importance of antioxidants to human health. Expert authors discuss the importance of a diet rich in Omega-3 Fatty acids for successful human growth and development and for the prevention of disease. Chapters highlight their contribution to the prevention and amelioration of a wide range of conditions such as heart disease, diabetes, arthritis, cancer, obesity, mental health and bone health. An indispensable text designed for nutritionists, dietitians, clinicians and health related professionals, Omega-3 Fatty Acids: Keys to Nutritional Health presents a comprehensive assessment of the current knowledge about the nutritional effects of Omega-3 fatty acids and their delivery in foods.

Free Radicals and Inflammation

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Publisher : Springer
ISBN 13 : 3034884826
Total Pages : 260 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Free Radicals and Inflammation by : Paul G. Winyard

Download or read book Free Radicals and Inflammation written by Paul G. Winyard and published by Springer. This book was released on 2013-03-11 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: As in so many fields of scientific endeavour following the molecular biology revo lution, our knowledge of the role of radicals not only in pathological states, but in basic physiology has developed exponentially. Indeed, our evolving concepts have, like so many political parties, been forced into dramatic "V-turns" and contortions. Within our working lives, we have had to debate whether radicals made any con tribution to any pathology, whilst now it is difficult not to entertain the view that every physiological process is pivotally controlled by exquisitely sensitive radical reactions. Inflammation is, of course, an example of pathology evolving from physiology, and in this book we have called upon both scientists and clinicians who have research interests in the complex switching mechanisms that sustain these transi tions. The book as a whole explores, from a physiological standpoint, how deter ministic radical systems sensitive to their initial conditions can interdigitate, iterate and feed back to control diverse cellular processes that create the inflammatory response. Whilst systems such as these to a mathematician would provide the basis for a chaotic response, one is forced to marvel how, for all stages of an inflammatory reaction, this system appears exquisitely controlled, making therapeutic manipula tion both possible and, to some extent, predictable.

Leucocyte Trafficking

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Publisher : Springer Science & Business Media
ISBN 13 : 3662053977
Total Pages : 258 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Leucocyte Trafficking by : A. Hamann

Download or read book Leucocyte Trafficking written by A. Hamann and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential component of inflammation is the migration of circulating leukocytes from blood into tissues. This process is characterized by a multistep paradigm of sequential cell adhesion and activation events that lead to the extravasation of specific leukocyte subsets to different tissues in health and disease. The first step of leukocyte extravasation, the rolling of leukocytes, is primarily mediated by the interactions of selectins and their ligands. It has recently become evident that fucosyltransferases are crucial for selectin ligand synthesis, inflammation, and skin homing. This book provides an in-depth overview of the mechanisms of leukocyte trafficking and of the molecular mechanisms of selectin/selectin ligand interactions and discusses options for pharmacological intervention to treat inflammatory diseases.

Neuroendocrine Immune Basis of the Rheumatic Diseases II

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Publisher :
ISBN 13 :
Total Pages : 544 pages
Book Rating : 4.X/5 (4 download)

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Book Synopsis Neuroendocrine Immune Basis of the Rheumatic Diseases II by : Maurizio Cutolo

Download or read book Neuroendocrine Immune Basis of the Rheumatic Diseases II written by Maurizio Cutolo and published by . This book was released on 2002 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of a September 21-23, 2001 conference. The papers in this volume examine the basic biochemical pathways from hormone metabolism to immune and inflammatory responses, as well as the effects of cytokines and glucocorticoid interactions in inflammatory diseases such as rheumatoid arthritis. Additional papers study the CNS and stress response involvement in autoimmune diseases including SLE (Systemic Lupus Erythematosus). Included are two overview articles that review the basic and clinical progress made over the past ten years in understanding and treating the rheumatic diseases.

Cumulated Index Medicus

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Author :
Publisher :
ISBN 13 :
Total Pages : 1844 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1844 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Diagnosis and Management of Ovarian Disorders

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Publisher : Elsevier
ISBN 13 : 008049451X
Total Pages : 595 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Diagnosis and Management of Ovarian Disorders by : Albert Altchek

Download or read book Diagnosis and Management of Ovarian Disorders written by Albert Altchek and published by Elsevier. This book was released on 2003-09-04 with total page 595 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated second edition of Diagnosis and Management of Ovarian Disorders provides thorough, yet succinct insight into the ever-changing realm of ovarian disorders. It presents a novel multidisciplinary approach to the subject as described by clinicians, surgeons, pathologists, basic scientists and related medical researchers. Topics covered include reproductive technology, early diagnosis of ovarian cancer, and management of menopause among others. The breadth of information provided by this book will appeal to clinicians and researchers involved in the study and treatment of ovarian disorders. KEY FEATURES* Includes updated information on early diagnosis of ovarian cancer* Reviews new diagnostic techniques for ovarian disorders* Discusses latest information on reproductive technology* Presents translational treatment linking laboratory research with clinical medicine

Genetic Steroid Disorders

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Publisher : Academic Press
ISBN 13 : 0128214252
Total Pages : 470 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Genetic Steroid Disorders by : Maria I. New

Download or read book Genetic Steroid Disorders written by Maria I. New and published by Academic Press. This book was released on 2023-06-14 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic Steroid Disorders, Second Edition targets adult and pediatric endocrinologists, clinical geneticists, genetic counselors, reproductive endocrinologists, neonatologists, urologists, and psychoendocrinologists. It is designed to assist these specialists in the diagnosis and treatment of steroid disorders. This revision includes a new chapter on "Gonadotropins, Obesity and Bone" and new research on non-invasive prenatal diagnosis with cell-free DNA. Chapters are thoroughly updated covering steroid disorders, the genetic bases for the disorder and case presentations, This definitive reference belongs in every medical library! Presents a comprehensive, translational look at all aspects of genetic steroid disorders in one reference work Provides a common language for endocrinologists, geneticists, molecular pathologists, and genetic counselors to discuss and diagnose genetic steroid disorders Saves clinicians and researchers time in quickly accessing the very latest details on genetic tests and diagnoses as opposed to searching through thousands of journal articles Highlights significant discoveries with clinical relevance, presenting insight into which medications to use based on the genetic makeup of a patient Teaches the best strategies and most effective use of genetic information in the patient counseling setting

The Cumulative Book Index

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Author :
Publisher :
ISBN 13 :
Total Pages : 2362 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Cumulative Book Index by :

Download or read book The Cumulative Book Index written by and published by . This book was released on 1998 with total page 2362 pages. Available in PDF, EPUB and Kindle. Book excerpt: A world list of books in the English language.

Hypertension in Postmenopausal Women

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Publisher : Springer Science & Business Media
ISBN 13 : 3642790771
Total Pages : 125 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Hypertension in Postmenopausal Women by : Michel E. Safar

Download or read book Hypertension in Postmenopausal Women written by Michel E. Safar and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt: On the occasion of the symposium on Hypertension in Postmenopausal Women (Monte Carlo, January 19-22, 1994), international scientists and clinicians discussed the various aspects of high blood pressure in older women. This volume presents an overview of this important aspect of both cardiology and gynecology. Special emphasis is given to the different approaches to antihypertension treatment.

Sex Differences in Cardiovascular Physiology and Pathophysiology

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Publisher : Academic Press
ISBN 13 : 0128131985
Total Pages : 392 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Sex Differences in Cardiovascular Physiology and Pathophysiology by : Babbette LaMarca

Download or read book Sex Differences in Cardiovascular Physiology and Pathophysiology written by Babbette LaMarca and published by Academic Press. This book was released on 2019-04-09 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sex Differences in Cardiovascular Physiology and Pathophysiology is a comprehensive look into the often overlooked and underappreciated fundamental sex differences between men and women and how those differences affect the cardiovascular system. It covers cardiovascular function, anatomy, cell signaling and the development of pathology. With contributions from world-renowned research investigators, this up-to-date reference compiles critical knowledge on cardiovascular sex differences, providing researchers and clinicians with a better understanding of the diagnosis, prevention and treatment of cardiovascular diseases in both men and women. Identifies the fundamental sex differences in the physiology and pathophysiology of the cardiovascular system Describes cell signaling pathways involved in sex-associated cardiovascular function and diseases Puts the sex differences in cardiovascular diseases in the forefront to improve cardiovascular prognoses

Index Medicus

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Author :
Publisher :
ISBN 13 :
Total Pages : 2098 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Index Medicus by :

Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2098 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

MRCOG Part One

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Publisher : Cambridge University Press
ISBN 13 : 1107667135
Total Pages : 557 pages
Book Rating : 4.1/5 (76 download)

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Book Synopsis MRCOG Part One by : Alison Fiander

Download or read book MRCOG Part One written by Alison Fiander and published by Cambridge University Press. This book was released on 2016-10-13 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fully updated and illustrated handbook providing comprehensive coverage of all curriculum areas covered by the MRCOG Part 1 examination.

Bibliography of Agriculture

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Author :
Publisher :
ISBN 13 :
Total Pages : 652 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Bibliography of Agriculture by :

Download or read book Bibliography of Agriculture written by and published by . This book was released on 1998 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: