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Nicotinic Acetylcholine Receptors In Health And Disease
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Book Synopsis Nicotinic Acetylcholine Receptors in Health and Disease by : R. Thomas Boyd
Download or read book Nicotinic Acetylcholine Receptors in Health and Disease written by R. Thomas Boyd and published by Academic Press. This book was released on 2023-03-14 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nicotinic Acetylcholine Receptors in Health and Disease provides the latest information Nicotinic acetylcholine receptors (nAChRs), which are involved in numerous diseases, including Alzheimer’s, Parkinson’s, and schizophrenia, and are important potential translational targets for treatment of these diseases, as well as therapy for addiction. This book focuses on the roles and function of nAChRs inside and outside of the nervous system, with an emphasis on translational implications and future prospects for the treatment of numerous disorders. This greater understanding of the basic neurobiology and clinical roles of nAChRs provides important insights for future clinical treatments of many major disorders. Describes the roles, expression and function of nicotinic receptors Includes receptor involvement, both inside and outside the nervous system Details nicotinic receptor involvement in Alzheimer’s, Parkinson’s, Cancer, Schizophrenia, and more Emphasizes future treatment prospects of disorders via modulation of nAChR signaling
Book Synopsis The Muscle-type Nicotinic Acetylcholine Receptor in Health and Disease by : Hakan Cetin
Download or read book The Muscle-type Nicotinic Acetylcholine Receptor in Health and Disease written by Hakan Cetin and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Neuronal Nicotinic Acetylcholine Receptors in the Human Thalamus and Related Brain Areas in Health and Disease by : Melissa Ray
Download or read book Neuronal Nicotinic Acetylcholine Receptors in the Human Thalamus and Related Brain Areas in Health and Disease written by Melissa Ray and published by . This book was released on 2005 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Nicotinic Acetylcholine Receptor Signaling in Neuroprotection by : Akinori Akaike
Download or read book Nicotinic Acetylcholine Receptor Signaling in Neuroprotection written by Akinori Akaike and published by Springer. This book was released on 2018-04-04 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book presents the roles and mechanisms of signal transduction triggered by nicotinic acetylcholine receptors (nAChRs) stimulation in neuroprotection against toxic effects of risk factors of neurodegenerative diseases. Accumulating evidence suggests that nAChRs in the CNS play important roles not only in excitatory neurotransmission but also in neuronal survival and related functions. Neuroprotection mediated by nAChRs in neurodegenerative diseases such as Alzheimer's disease is the major topic of this book. In response to rapidly evolving areas in clinical and laboratory neuropharmacology and neurochemistry, this volume provides in-depth coverage of neuroprotection in basic research and future developments in the clinical application of effective neuroprotective strategies in neurodegenerative diseases. This work appeals to both basic and clinical researchers in several fields, such as neuroscience, neurology, and pharmacology.
Book Synopsis Nicotinic Receptors by : Robin A.J. Lester
Download or read book Nicotinic Receptors written by Robin A.J. Lester and published by Springer. This book was released on 2014-11-11 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive overview of nicotinic receptors that addresses their history from crystal structure to behavior as well as their implications in disease and potential as therapeutic targets. It includes background information on all subtypes of nicotinic receptors, the most recent information on the distribution throughout the nervous system and discussion of their implications in learning and memory, addiction and neurological and psychiatric disease such as Alzheimer's and Parkinson's. Takes advantage of several recent developments in the fields of optogenetics, viral expression and gene analysis to focus on current knowledge on the functional aspects of nicotinic receptors.
Book Synopsis The Nicotinic Acetylcholine Receptor by : Francisco Jose Barrantes
Download or read book The Nicotinic Acetylcholine Receptor written by Francisco Jose Barrantes and published by Springer. This book was released on 2013-12-17 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Acetylcholine Receptors in Health and Disease by : Adelais Eros Gupta
Download or read book Acetylcholine Receptors in Health and Disease written by Adelais Eros Gupta and published by Nova Medicine and Health. This book was released on 2019 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acetylcholine Receptors in Health and Disease opens with a review of the results of an investigation on the cholinergic modulation of excitatory synaptic transmission in the frog tectum carried out in the laboratory of neurophysiology at the Lithuanian University of Health Sciences. Experiments were done in vivo on the common grass frog Rana temporaria. Next, the authors review the function of M4 MR and discuss possible detection methods. M4 MR regulated locomotion is studied in conjunction with recent data on consequences to biorhythms. In the closing chapter, the authors review the environmental enrichment paradigm in rodents, as well as their effects on neurobiological, physiological and behavioral variables in preclinical studies.
Book Synopsis Nicotinic Acetylcholine Receptor Signaling in Neuroprotection by : Shun Shimohama
Download or read book Nicotinic Acetylcholine Receptor Signaling in Neuroprotection written by Shun Shimohama and published by . This book was released on 2020-10-08 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book presents the roles and mechanisms of signal transduction triggered by nicotinic acetylcholine receptors (nAChRs) stimulation in neuroprotection against toxic effects of risk factors of neurodegenerative diseases. Accumulating evidence suggests that nAChRs in the CNS play important roles not only in excitatory neurotransmission but also in neuronal survival and related functions. Neuroprotection mediated by nAChRs in neurodegenerative diseases such as Alzheimer's disease is the major topic of this book. In response to rapidly evolving areas in clinical and laboratory neuropharmacology and neurochemistry, this volume provides in-depth coverage of neuroprotection in basic research and future developments in the clinical application of effective neuroprotective strategies in neurodegenerative diseases. This work appeals to both basic and clinical researchers in several fields, such as neuroscience, neurology, and pharmacology. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.
Book Synopsis Nicotinic Acetylcholine Receptors by : Jean-Pierre Changeux
Download or read book Nicotinic Acetylcholine Receptors written by Jean-Pierre Changeux and published by ODILE JACOB PUBLISHING CORP. This book was released on 2005-09-08 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: The acetylcholine nicotinic receptor is among the most studied receptors in neuroscience. Involved in muscle contraction and a wide variety of other neurological functions, including the processing of nicotine, it was the first receptor to be isolated and observed at the molecular level, providing a major research pathway for scientists working in neuroscience, biochemistry, pharmacology, and behavioral science. This book describes four decades of scientific research that inform our current understanding of this receptor. Jean-Pierre Changeux and Stuart J. Edelstein played important roles in pioneering research on the acetylcholine nicotinic receptor and on allosteric proteins, and here they reveal the complete scientific trajectory of that research. They begin with a historical perspective, describing how several fields converged around a single receptor and then explain the initial receptor purification and characterization. Subsequent chapters trace the investigations into various aspects of receptor structure and function, including the chemical structure of the binding site, the identity and properties of the ion channel, and the mechanism of signal transmission. In the final portion of the book, Changeux and Edelstein discuss recent studies on the three-dimensional structure of the receptor molecule and share their novel understanding of inherited diseases such as congenital myasthenia and epilepsy. They also address the integration of the receptor into its synaptic membrane environment and its distribution, physiology, and regulation in brain functions and cognition. Richly illustrated and lucidly written, this book provides an exceptional opportunity for scientists and students to follow a historic advance in our knowledge of molecular mechanisms and the workings of the brain.
Book Synopsis Nicotinic Acetylcholine Receptors in the Nervous System by : Francesco Clementi
Download or read book Nicotinic Acetylcholine Receptors in the Nervous System written by Francesco Clementi and published by Springer. This book was released on 1988-12-22 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the NATO Advanced Research Workshop on Nicotine Acetylcholine Receptors in the Nervous System held in Venice, Italy, April 18-21, 1988
Download or read book Neuroimaging written by Peter Bright and published by IntechOpen. This book was released on 2012-03-09 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern neuroimaging tools allow unprecedented opportunities for understanding brain neuroanatomy and function in health and disease. Each available technique carries with it a particular balance of strengths and limitations, such that converging evidence based on multiple methods provides the most powerful approach for advancing our knowledge in the fields of clinical and cognitive neuroscience. The scope of this book is not to provide a comprehensive overview of methods and their clinical applications but to provide a "snapshot" of current approaches using well established and newly emerging techniques.
Book Synopsis Neuronal Nicotinic Acetylcholine Receptors by : Richard Aragon
Download or read book Neuronal Nicotinic Acetylcholine Receptors written by Richard Aragon and published by . This book was released on 2005 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Animal Models of Cognitive Impairment by : Edward D. Levin
Download or read book Animal Models of Cognitive Impairment written by Edward D. Levin and published by CRC Press. This book was released on 2006-06-22 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: The costs associated with a drug's clinical trials are so significant that it has become necessary to validate both its safety and efficacy in animal models prior to the continued study of the drug in humans. Featuring contributions from distinguished researchers in the field of cognitive therapy research, Animal Models of Cognitive Impairmen
Book Synopsis Nicotinic Acetylcholine Receptor by : Alfred Maelicke
Download or read book Nicotinic Acetylcholine Receptor written by Alfred Maelicke and published by Springer. This book was released on 1986-12-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the NATO Advanced Research Workshop on Mechanism of Action of the Nicotinic Acetylcholine Receptors held on the Island of Santorini, Greece, May 19-23, 1986
Book Synopsis Enteric Glia by : Brian D. Gulbransen
Download or read book Enteric Glia written by Brian D. Gulbransen and published by Biota Publishing. This book was released on 2014-07-01 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: The enteric nervous system (ENS) is a complex neural network embedded in the gut wall that orchestrates the reflex behaviors of the intestine. The ENS is often referred to as the “little brain” in the gut because the ENS is more similar in size, complexity and autonomy to the central nervous system (CNS) than other components of the autonomic nervous system. Like the brain, the ENS is composed of neurons that are surrounded by glial cells. Enteric glia are a unique type of peripheral glia that are similar to astrocytes of the CNS. Yet enteric glial cells also differ from astrocytes in many important ways. The roles of enteric glial cell populations in the gut are beginning to come to light and recent evidence implicates enteric glia in almost every aspect of gastrointestinal physiology and pathophysiology. However, elucidating the exact mechanisms by which enteric glia influence gastrointestinal physiology and identifying how those roles are altered during gastrointestinal pathophysiology remain areas of intense research. The purpose of this e-book is to provide an introduction to enteric glial cells and to act as a resource for ongoing studies on this fascinating population of glia. Table of Contents: Introduction / A Historical Perspective on Enteric Glia / Enteric Glia: The Astroglia of the Gut / Molecular Composition of Enteric Glia / Development of Enteric Glia / Functional Roles of Enteric Glia / Enteric Glia and Disease Processes in the Gut / Concluding Remarks / References / Author Biography
Book Synopsis Nicotinic Acetylcholine Receptor by : Alfred Maelicke
Download or read book Nicotinic Acetylcholine Receptor written by Alfred Maelicke and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the NATO Advanced Research Workshop on Mechanism of Action of the Nicotinic Acetylcholine Receptors held on the Island of Santorini, Greece, May 19-23, 1986
Book Synopsis Tobacco Smoking and Nicotine by : William R. Martin
Download or read book Tobacco Smoking and Nicotine written by William R. Martin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nicotine is the major factor in the continuation of the smoking habit among humans. On December 2-4, 1985, under the sponsorship of the Tobacco and Health Research Institute in Lexington, Kentucky, leading scientists from around the world whose research efforts have focused on the role of nicotine in the tobacco habit participated in an International Symposium to provide the most comprehensive and ~xtensive coverage of this topic so far. The material discussed was in the forefront of man's knowledge about nicotine, and both lectures and question and answer sessions were stimulating and enlightening. This publication contains the manuscripts presented at the Symposium, along with an Overview prepared by selected individuals. Lecture and poster session topics are delineated more fully in the Overview. This volume is expected to serve as a definitive reference on nicotine as it relates to the tobacco habit. Symposium sessions were arranged under four headings: (1) behavioral effects of nicotine and nicotine~ependence in humans and animals, (2) neurohumoral regulation of neuroendocrine and cardiovascular function by nicotine, (3) neuropharmacology of nicotine, and (4) neurochemistry. This was the first assembly of this magnitude of scientists who had devoted years of research to nicotine and its effects. Indeed, it was a pleasure to have sponsored this important event. Dr. Lay ten Davis, Director Tobacco and Health Research Institute Cooper and Alumni Drives Lexington, KY 40546-0236 v ACKNOWLEDGMENTS The Editors of this volume express sincere appreciation to all of the contributors. Special acknowledgments are given to Ms.
