New Toxicology for Old

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Publisher : Springer Science & Business Media
ISBN 13 : 3642685110
Total Pages : 398 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis New Toxicology for Old by : P.L. Chambers

Download or read book New Toxicology for Old written by P.L. Chambers and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nervous system is in the most cases a likely target for the untoward effects of chemicals. The harmful consequences affect primarily the individual but may also considerably strain the whole society. The consumption of ethanol is a glaring example (National Institute on Alcohol Abuse and Alcoholism 1978). As ethanol, many organic liquids have similar immediate effects on the nervous system. The rapidity of the response suggests the involvement of the neuronal communication. The nervous system is also vulnerable to the depletion of oxygen, another common cause for the rapid deterioration of the brain function. It is quite impossible to list all the effects produced by the very large number of the individual chemicals. It would be more fruitful to try to understand the characteristics of the nervous system and the biochemical toxic mechanisms in the evaluation of the neurotoxicity of chemicals. Transfer of Xenobiotics in the Brain The adult central nervous system displays a functional barrier toward the blood-borne chemicals so that water-soluble compounds with an approximate molecular weight above 100 are largely prevented from directly entering the brain (Bradbury 1979). The functional barrier has morphological features typical to it and has a very close association of adjacent capillary cells separated by clefts of 12 A wide (Jacobs 1978). The nervous system capillaries are enveloped by glial cell tongues, and these pericytes contain contractile elements (Le Beux and Willemot 1978a, b) so that the capillaries can be constricted.

Medical Toxicology of Natural Substances

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Publisher : John Wiley & Sons
ISBN 13 : 1118382765
Total Pages : 1196 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis Medical Toxicology of Natural Substances by : Donald G. Barceloux

Download or read book Medical Toxicology of Natural Substances written by Donald G. Barceloux and published by John Wiley & Sons. This book was released on 2012-03-07 with total page 1196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest and information in the field of medical toxicology has grown rapidly, but there has never been a concise, authoritative reference focused on the subjects of natural substances, chemical and physical toxins, drugs of abuse, and pharmaceutical overdoses. Medical Toxicology of Natural Substances finally gives you an easily accessible resource for vital toxicological information on foods, plants, and animals in key areas in the natural environment.

Forging a Poison Prevention and Control System

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Publisher : National Academies Press
ISBN 13 : 0309091942
Total Pages : 369 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Forging a Poison Prevention and Control System by : Institute of Medicine

Download or read book Forging a Poison Prevention and Control System written by Institute of Medicine and published by National Academies Press. This book was released on 2004-09-16 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Poisoning is a far more serious health problem in the U.S. than has generally been recognized. It is estimated that more than 4 million poisoning episodes occur annually, with approximately 300,000 cases leading to hospitalization. The field of poison prevention provides some of the most celebrated examples of successful public health interventions, yet surprisingly the current poison control "system" is little more than a loose network of poison control centers, poorly integrated into the larger spheres of public health. To increase their effectiveness, efforts to reduce poisoning need to be linked to a national agenda for public health promotion and injury prevention. Forging a Poison Prevention and Control System recommends a future poison control system with a strong public health infrastructure, a national system of regional poison control centers, federal funding to support core poison control activities, and a national poison information system to track major poisoning epidemics and possible acts of bioterrorism. This framework provides a complete "system" that could offer the best poison prevention and patient care services to meet the needs of the nation in the 21st century.

Toxicology in Antiquity

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Publisher : Academic Press
ISBN 13 : 0128153407
Total Pages : 511 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Toxicology in Antiquity by :

Download or read book Toxicology in Antiquity written by and published by Academic Press. This book was released on 2018-10-22 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicology in Antiquity provides an authoritative and fascinating exploration into the use of toxins and poisons in antiquity. It brings together the two previously published shorter volumes on the topic, as well as adding considerable new information. Part of the History of Toxicology and Environmental Health series, it covers key accomplishments, scientists, and events in the broad field of toxicology, including environmental health and chemical safety. This first volume sets the tone for the series and starts at the very beginning, historically speaking, with a look at toxicology in ancient times. The book explains that before scientific research methods were developed, toxicology thrived as a very practical discipline. People living in ancient civilizations readily learned to distinguish safe substances from hazardous ones, how to avoid these hazardous substances, and how to use them to inflict harm on enemies. It also describes scholars who compiled compendia of toxic agents. New chapters in this edition focus chiefly on evidence for the use of toxic agents derived from religious texts. - Provides the historical background for understanding modern toxicology - Illustrates the ways previous civilizations learned to distinguish safe from hazardous substances, how to avoid the hazardous substances and how to use them against enemies - Explores the way famous historical figures used toxins - New chapters focus on evidence of the use of toxins derived from religious texts

Poisoning in the Modern World

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 1838807853
Total Pages : 130 pages
Book Rating : 4.8/5 (388 download)

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Book Synopsis Poisoning in the Modern World by : Ozgur Karcioglu

Download or read book Poisoning in the Modern World written by Ozgur Karcioglu and published by BoD – Books on Demand. This book was released on 2019-06-19 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over 400 years ago, Swiss alchemist and physician Paracelsus (1493-1541) cited: "All substances are poisons; there is none that is not a poison. The right dose differentiates a poison from a remedy." This is often condensed to: "The dose makes the poison." So, why are we overtly anxious about intoxications?In fact, poisons became a global problem with the industrial revolution. Pesticides, asbestos, occupational chemicals, air pollution, and heavy metal toxicity maintain high priority worldwide, especially in developing countries. Children between 0 and 5 years old are the most vulnerable to both acute and chronic poisonings, while older adults suffer from the chronic effects of chemicals. This book aims to raise awareness about the challenges of poisons, to help clinicians understand current issues in toxicology.

Environmental Neurotoxicology

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Publisher : National Academies Press
ISBN 13 : 0309045312
Total Pages : 167 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Environmental Neurotoxicology by : National Research Council

Download or read book Environmental Neurotoxicology written by National Research Council and published by National Academies Press. This book was released on 1992-02-01 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.

A Textbook of Modern Toxicology

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Author :
Publisher : McGraw-Hill Medical Publishing
ISBN 13 :
Total Pages : 518 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis A Textbook of Modern Toxicology by : Ernest Hodgson

Download or read book A Textbook of Modern Toxicology written by Ernest Hodgson and published by McGraw-Hill Medical Publishing. This book was released on 1997 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised edition reflects changes in the core curriculum subjects covered in the basic toxicology course for graduate students. Designed as an introductory textbook, it emphasizes the fundamental basis of toxic action at the cellular and molecular levels and lays the foundation for specialized courses in toxicology. Additional topics include metabolic activation and cellular protection, clinical toxicology diagnosis and treatment, ecosystems, environmental toxicology, ecotoxicology, case histories, and future consideration for environmental and human health.

Aging in Today's Environment

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Publisher : National Academies
ISBN 13 :
Total Pages : 238 pages
Book Rating : 4.1/5 (324 download)

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Book Synopsis Aging in Today's Environment by : National Research Council (U.S.). Committee on Chemical Toxicity and Aging

Download or read book Aging in Today's Environment written by National Research Council (U.S.). Committee on Chemical Toxicity and Aging and published by National Academies. This book was released on 1987 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report examines the relationships between aging and exposure to environmental agents (including natural and man-made agents, as well as life-style factors). Several relationships must be considered--the impact of intermittent or lifelong exposure to environmental agents on the rate of aging, the impact of lifelong exposure on health status when one reaches more advanced age, and the special response of the aged compared with that of the young when exposed to environmental agents.

Green Toxicology

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Publisher : Royal Society of Chemistry
ISBN 13 : 1839164409
Total Pages : 225 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis Green Toxicology by : Alexandra Maertens

Download or read book Green Toxicology written by Alexandra Maertens and published by Royal Society of Chemistry. This book was released on 2022-02-01 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Green toxicology is an integral part of green chemistry. One of the key goals of green chemistry is to design less toxic chemicals. Therefore, an understanding of toxicology and hazard assessment is important for any chemist working in green chemistry, but toxicology is rarely part of most chemists' education. As a consequence, chemists lack the toxicological lens necessary to view chemicals in order to design safer substitutions. This book seeks to fill that gap and demonstrate how a basic understanding of toxicology, as well as the tools of in silico and in vitro toxicology, can be an integral part of green chemistry. R&D chemists, product stewards, and toxicologists who work in the field of sustainability, can all benefit from integrating green toxicology principles into their work. Topics include in silico tools for hazard assessment, toxicity testing, and lifecycle considerations, this book aims to act as a bridge between green toxicologists and green chemists.

Toxicological Profile for Lead

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Author :
Publisher :
ISBN 13 :
Total Pages : 584 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Toxicological Profile for Lead by :

Download or read book Toxicological Profile for Lead written by and published by . This book was released on 2007 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Medical Toxicology of Drug Abuse

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Publisher : John Wiley & Sons
ISBN 13 : 1118106059
Total Pages : 1080 pages
Book Rating : 4.1/5 (181 download)

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Book Synopsis Medical Toxicology of Drug Abuse by : Donald G. Barceloux

Download or read book Medical Toxicology of Drug Abuse written by Donald G. Barceloux and published by John Wiley & Sons. This book was released on 2012-02-03 with total page 1080 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a broad reference covering important drugs of abuse including amphetamines, opiates, and steroids. It also covers psychoactive plants such as caffeine, peyote, and psilocybin. It provides chemical structures, analytical methods, clinical features, and treatments of these drugs of abuse, serving as a highly useful, in-depth supplement to a general medical toxicology book. The style allows for the easy application of the contents to searchable databases and other electronic products, making this an essential resource for practitioners in medical toxicology, industrial hygiene, occupational medicine, pharmaceuticals, environmental organizations, pathology, and related fields.

Pesticides in the Diets of Infants and Children

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Publisher : National Academies Press
ISBN 13 : 0309048753
Total Pages : 402 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Pesticides in the Diets of Infants and Children by : National Research Council

Download or read book Pesticides in the Diets of Infants and Children written by National Research Council and published by National Academies Press. This book was released on 1993-02-01 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many of the pesticides applied to food crops in this country are present in foods and may pose risks to human health. Current regulations are intended to protect the health of the general population by controlling pesticide use. This book explores whether the present regulatory approaches adequately protect infants and children, who may differ from adults in susceptibility and in dietary exposures to pesticide residues. The committee focuses on four major areas: Susceptibility: Are children more susceptible or less susceptible than adults to the effects of dietary exposure to pesticides? Exposure: What foods do infants and children eat, and which pesticides and how much of them are present in those foods? Is the current information on consumption and residues adequate to estimate exposure? Toxicity: Are toxicity tests in laboratory animals adequate to predict toxicity in human infants and children? Do the extent and type of toxicity of some chemicals vary by species and by age? Assessing risk: How is dietary exposure to pesticide residues associated with response? How can laboratory data on lifetime exposures of animals be used to derive meaningful estimates of risk to children? Does risk accumulate more rapidly during the early years of life? This book will be of interest to policymakers, administrators of research in the public and private sectors, toxicologists, pediatricians and other health professionals, and the pesticide industry.

Hamilton and Hardy's Industrial Toxicology

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Publisher : John Wiley & Sons
ISBN 13 : 0470929731
Total Pages : 1364 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Hamilton and Hardy's Industrial Toxicology by : Raymond D. Harbison

Download or read book Hamilton and Hardy's Industrial Toxicology written by Raymond D. Harbison and published by John Wiley & Sons. This book was released on 2015-04-13 with total page 1364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a concise, yet comprehensive, reference on all aspects of industrial exposures and toxicants; this book aids toxicologists, industrial hygienists, and occupational physicians to investigate workplace health problems. • Updates and expands coverage with new chapters covering regulatory toxicology, toxicity testing, physical hazards, high production volume (HPV) chemicals, and workplace drug use • Includes information on occupational and environmental sources of exposure, mammalian toxicology, industrial hygiene, medical management and ecotoxicology • Retains a succinct chapter format that has become the hallmark for the previous editions • Distils a vast amount of information into one resource for both academics and professionals

Forensic Toxicology

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Publisher : Royal Society of Chemistry
ISBN 13 : 1788018109
Total Pages : 590 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Forensic Toxicology by : Susannah Davies

Download or read book Forensic Toxicology written by Susannah Davies and published by Royal Society of Chemistry. This book was released on 2019-03-15 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: New designer drugs, access to databases, and changing availability of samples for analysis have changed the face of modern forensic toxicology in recent years. Forensic Toxicology: Drug Use and Misuse brings together the latest information direct from experts in each sub-field of the discipline providing a broad overview of current thinking and the most innovative approaches to case studies. The text begins with an in-depth discussion of pharmaco­epidemiology, including information on the value of nationwide databases in forensic toxicology. The use and abuse of drugs in driving, sport and the workplace are then discussed by industry experts who are conducting case work in their field. Not only are new drug groups discussed (NPS), but also their constantly changing impact on drug legislation. Synthetic cannabinoids, khat and mephodrone are discussed in detail. Following a section devoted to legislation and defence, readers will find comprehensive chapters covering sample choice reflecting the increasing use of hair and oral fluid, and also the less commonly used sweat and nail analysis. New and old case examples are compared and contrasted in the final part of the book, which will enable readers to understand how drugs impact on each other and how the interpretative outcome of a case are dependent on many aspects. From use of pharmaceutical drugs in a clinical setting, through smart drugs to new psychoactive drugs, this book documents the wide range in which drugs today are abused. This book will be an essential resource for postgraduate students in forensic toxicology, and for researchers in forensic toxicology laboratories who need the latest data and knowledge.

Behavioral Measures of Neurotoxicity

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Author :
Publisher : National Academies Press
ISBN 13 : 0309040477
Total Pages : 449 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Behavioral Measures of Neurotoxicity by : National Research Council

Download or read book Behavioral Measures of Neurotoxicity written by National Research Council and published by National Academies Press. This book was released on 1990-02-01 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exposure to toxic chemicalsâ€"in the workplace and at homeâ€"is increasing every day. Human behavior can be affected by such exposure and can give important clues that a person or population is in danger. If we can understand the mechanisms of these changes, we can develop better ways of testing for toxic chemical exposure and, most important, better prevention programs. This volume explores the emerging field of neurobehavioral toxicology and the potential of behavior studies as a noninvasive and economical means for risk assessment and monitoring. Pioneers in this field explore its promise for detecting environmental toxins, protecting us from exposure, and treating those who are exposed.

Toxicology of Cyanides and Cyanogens

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Publisher : John Wiley & Sons
ISBN 13 : 1118628942
Total Pages : 369 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Toxicology of Cyanides and Cyanogens by : Alan H. Hall

Download or read book Toxicology of Cyanides and Cyanogens written by Alan H. Hall and published by John Wiley & Sons. This book was released on 2015-10-13 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: The basic and applied toxicology of cyanides and cyanogens has widespread commercial, occupational, environmental, clinical, forensic, military, and public health implications. This book provides a detailed and updated reference describing the properties, uses, general and human toxicology, clinical recognition, diagnosis and medical management, and countermeasures is therefore required in academic, medical, occupational, environmental, medico-legal, regulatory, emergency response, and military arenas. Edited by a world-renowned team of experts from academia, defense and industry, this book will be an invaluable reference for professionals, researchers and students in cyanide and cyanogens.

How Tobacco Smoke Causes Disease

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Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General

Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.