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New Strategies For Treatment Of Sepsis
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Book Synopsis New Strategies for Treatment of Sepsis by : Antonio Mirijello
Download or read book New Strategies for Treatment of Sepsis written by Antonio Mirijello and published by Mdpi AG. This book was released on 2021-12-27 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents a collection of paper from different specialists involved in the management of septic patients, aimed to disseminate the knowledge in the field of sepsis, particularly to non-intensivists physicians.
Book Synopsis Sepsis Management in Resource-limited Settings by : Arjen M. Dondorp
Download or read book Sepsis Management in Resource-limited Settings written by Arjen M. Dondorp and published by Springer. This book was released on 2019-02-08 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More than eighty percent of the worldwide deaths related to sepsis occur in resource-limited settings in low and middle-income countries. Current international sepsis guidelines cannot be implemented without adaptations towards these settings, mainly because of the difference in local resources and a different spectrum of infectious diseases causing sepsis. This prompted members of the Global Intensive Care working group of the European Society of Intensive Care Medicine (ESICM) and the Mahidol-Oxford Tropical Medicine Research Unit (MORU, Bangkok, Thailand) - among which the Editors – to develop with an international group of experts a comprehensive set of recommendations for the management of sepsis in resource-limited settings. Recommendations are based on both current scientific evidence and clinical experience of clinicians working in resource-limited settings. The book includes an overview chapter outlining the current challenges and future directions of sepsis management as well as general recommendations on the structure and organization of intensive care services in resource-limited settings. Specific recommendations on the recognition and management of patients with sepsis and septic shock in these settings are grouped into seven chapters. The book provides evidence-based practical guidance for doctors in low and middle income countries treating patients with sepsis, and highlights areas for further research and discussion.
Download or read book Sepsis written by Jordi Rello and published by Springer Science & Business Media. This book was released on 2008-06-26 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sepsis is an important public health problem around the world. Severe sepsis carries significant morbidity, mortality and high costs. The incidence of sepsis is increasing because of the aging population, the growing number of immunocompromised hosts, the increasing use of invasive procedures, and, to a lesser extent, antibiotic resistance among pathogens. Despite recent advances in the pathogenesis, diagnosis, and therapeutic approaches the mortality rate associated with this condition remains high. Therefore, the goal of Sepsis: New Strategies is to review novel targets to be considered in patients with severe sepsis and to assess new developments for patients with sepsis originating in the respiratory tract.
Download or read book Sepsis written by Jordi Rello and published by Springer. This book was released on 2009-08-29 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sepsis is an important public health problem around the world. Severe sepsis carries significant morbidity, mortality and high costs. The incidence of sepsis is increasing because of the aging population, the growing number of immunocompromised hosts, the increasing use of invasive procedures, and, to a lesser extent, antibiotic resistance among pathogens. Despite recent advances in the pathogenesis, diagnosis, and therapeutic approaches the mortality rate associated with this condition remains high. Therefore, the goal of Sepsis: New Strategies is to review novel targets to be considered in patients with severe sepsis and to assess new developments for patients with sepsis originating in the respiratory tract.
Download or read book Sepsis written by Derek J. Chadwick and published by John Wiley & Sons. This book was released on 2007-02-06 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sepsis: New Insights, New Therapies brings together contributions from an international group of experts in diverse fields to consider how the various pathways implicated in early and late sepsis interact, with a particular emphasis on novel concepts and potential new therapeutic approaches. Topics covered include adaptive immunity, inflammation, neuroendocrinology, bioenergetics and metabolism. Several chapters in the latter half of the book are particularly concerned with treatment strategies involving modulation of the neuroendocrine response. Addresses the frequent, but under-recognised condition of sepsis and discusses new ways to prevent and treat it Describes numerous pharmacological approaches to therapy for early and late sepsis Includes detailed discussion of the various physiological systems implicated in sepsis Presents an international perspective, featuring contributions from experts from laboratories worldwide involved in the study of sepsis Sepsis: New Insights, New Therapies is an invaluable resource for all critical care physicians and researchers. It is also informative reading for immunologists, endocrinologists, neuroendocrinologists, physiologists, and pharmacologists.
Download or read book Sepsis Management written by Jordi Rello and published by Springer Science & Business Media. This book was released on 2011-10-11 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is unique in approaching multiple organ dysfunction syndrome (MODS) from the perspective of its pathophysiological mechanism, and addressing aspects that are overlooked in most of the available literature. Eminent experts in the field from Europe and beyond offer new insights into risk stratification, severity assessment, and management of critically ill patients with sepsis. The principal focus is on recently developed concepts in infection management and in antibiotic use, bearing in mind that in these patients the pharmacokinetics of antibiotics are altered, affecting renal clearance and requiring dosage adjustments. The significance of the PIRO (predisposing factors, infection, response, organ dysfunction) model in the development of effective treatment strategies is emphasized. This book will be of interest and value to all who are involved in the treatment of, or research into, sepsis and MODS.
Book Synopsis Novel Therapeutic Strategies in the Treatment of Sepsis by : David Morrison
Download or read book Novel Therapeutic Strategies in the Treatment of Sepsis written by David Morrison and published by CRC Press. This book was released on 1995-10-12 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This up-to-the-minute, single-source reference examines the latest research efforts and preclinical approaches in the treatment of sepsis-discussing emerging ideas on mechanisms to combat septic shock and offering novel methods for interrupting the System Inflammatory Response Syndrome (SIRS) that leads to sepsis.
Book Synopsis Handbook of Sepsis by : W. Joost Wiersinga
Download or read book Handbook of Sepsis written by W. Joost Wiersinga and published by Springer. This book was released on 2018-04-13 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practically oriented book provides an up-to-date overview of all significant aspects of the pathogenesis of sepsis and its management, including within the intensive care unit. Readers will find information on the involvement of the coagulation and endocrine systems during sepsis and on the use of biomarkers to diagnose sepsis and allow early intervention. International clinical practice guidelines for the management of sepsis are presented, and individual chapters focus on aspects such as fluid resuscitation, vasopressor therapy, response to multiorgan failure, antimicrobial therapy, and adjunctive immunotherapy. The closing section looks forward to the coming decade, discussing novel trial designs, sepsis in low- and middle-income countries, and emerging management approaches. The book is internatio nal in scope, with contributions from leading experts worldwide. It will be of value to residents and professionals/practitioners in the fields of infectious diseases and internal medicine, as well as to GPs and medical students.
Author :Gandhi Bhaskar Patrudu Lanka Publisher :International Journal of Medical Conference Presentations (IJMCP), January 2020. Citation: Lanka Gandhi Bhaskar Patrudu, Belekar DM. Novel strategies for septic shock management: based on current guidelines and research. Presented at: 42nd Annual Conference of Maharashtra State Chapter of ASI (MASICON 2020); 2020 Jan 24; Amravati, India. Terna Medical College & Hospital, Nerul, Navi Mumbai. Published by International Journal of Medical Conference Presentations (IJMCP); January 2020. ISBN 13 : Total Pages :23 pages Book Rating :4./5 ( download)
Book Synopsis Novel Strategies for Septic Shock Management ( Based on Current Guidelunes and Research) by : Gandhi Bhaskar Patrudu Lanka
Download or read book Novel Strategies for Septic Shock Management ( Based on Current Guidelunes and Research) written by Gandhi Bhaskar Patrudu Lanka and published by International Journal of Medical Conference Presentations (IJMCP), January 2020. Citation: Lanka Gandhi Bhaskar Patrudu, Belekar DM. Novel strategies for septic shock management: based on current guidelines and research. Presented at: 42nd Annual Conference of Maharashtra State Chapter of ASI (MASICON 2020); 2020 Jan 24; Amravati, India. Terna Medical College & Hospital, Nerul, Navi Mumbai. Published by International Journal of Medical Conference Presentations (IJMCP); January 2020. . This book was released on 2020-01-24 with total page 23 pages. Available in PDF, EPUB and Kindle. Book excerpt: Paper Presented at 42nd annual Conference of Maharashtra State Chapter of ASI ( MASICON 2020) in Amravati on 24 January 2020. ) Abstract: Background: Septic shock remains a leading cause of mortality despite advances in critical care. Recent updates and guidelines have shifted clinical approaches to improve recognition and management. This review highlights the role of various clinical tools, interventions, and therapeutic strategies in managing septic shock. Objective: To examine the current clinical strategies and guidelines in recognizing and treating septic shock, with emphasis on occult septic shock, fluid resuscitation, vasopressor usage, and the role of steroids, lactate monitoring, and procalcitonin in prognosis. Methods: A comprehensive review of the literature, including the latest guidelines from the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3), the Surviving Sepsis Campaign, and retrospective studies comparing clinical tools such as SIRS, qSOFA, and NEWS for early identification of septic shock. Results: 1. Recognition of Septic Shock: - SIRS, qSOFA, and NEWS were evaluated, with NEWS emerging as a more accurate tool for early recognition. - Lactate and procalcitonin are valuable markers but have limitations in predicting patient outcomes.2. Resuscitation Strategies: - Ringer's Lactate is preferred over saline for initial resuscitation due to the latter’s association with hyperchloremic acidosis. - The recommended fluid resuscitation strategy includes rapid administration of 30mL/kg crystalloid for hypotension or lactate > 4 mmol/L.3. Vasopressor and Steroid Use: - Early norepinephrine administration is recommended to maintain a MAP > 65 mmHg. - Vasopressin is the second-line vasopressor, though its benefits in reducing mortality are uncertain. - Steroids, particularly in conjunction with vitamin C and thiamine, may improve outcomes in vasopressor-refractory septic shock.4. Antibiotic Timing and Administration: - Early antibiotic administration, ideally within one hour of sepsis diagnosis, significantly improves survival rates. Conclusion: Effective management of septic shock involves early recognition using appropriate clinical tools like NEWS, aggressive fluid resuscitation with balanced crystalloids, timely initiation of vasopressors, and careful consideration of steroids and antibiotics. Further large-scale randomized controlled trials are needed to refine these approaches, particularly in vasopressor and steroid administration.
Book Synopsis Chalk Talks in Internal Medicine by : Somnath Mookherjee
Download or read book Chalk Talks in Internal Medicine written by Somnath Mookherjee and published by Springer Nature. This book was released on 2020-09-30 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides teaching scripts for medical educators in internal medicine and coaches them in creating their own teaching scripts. Every year, thousands of attending internists are asked to train the next generation of physicians to master a growing body of knowledge. Formal teaching time has become increasingly limited due to rising clinical workload, medical documentation requirements, duty hour restrictions, and other time pressures. In addition, today’s physicians-in-training expect teaching sessions that deliver focused, evidence-based content that is integrated into clinical workflow. In keeping with both time pressures and trainee expectations, academic internists must be prepared to effectively and efficiently teach important diagnostic and management concepts. A teaching script is a methodical and structured plan that aids in effective teaching. The teaching scripts in this book anticipate learners’ misconceptions, highlight a limited number of teaching points, provide evidence to support the teaching points, use strategies to engage the learners, and provide a cognitive scaffold for teaching the topic that the teacher can refine over time. All divisions of internal medicine (e.g. cardiology, rheumatology, and gastroenterology) are covered and a section on undifferentiated symptom-based presentations (e.g. fatigue, fever, and unintentional weight loss) is included. This book provides well-constructed teaching scripts for commonly encountered clinical scenarios, is authored by experienced academic internists and allows the reader to either implement them directly or modify them for their own use. Each teaching script is designed to be taught in 10-15 minutes, but can be easily adjusted by the reader for longer or shorter talks. Teaching Scripts in Internal Medicine is an ideal tool for internal medicine attending physicians and trainees, as well as physician’s assistants, nurse practitioners, and all others who teach and learn internal medicine.
Book Synopsis Early-onset Neonatal Sepsis by : Karen D. Fairchild
Download or read book Early-onset Neonatal Sepsis written by Karen D. Fairchild and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Clinical Management of Shock by : Stanislaw P. Stawicki
Download or read book Clinical Management of Shock written by Stanislaw P. Stawicki and published by BoD – Books on Demand. This book was released on 2020-06-24 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shock is a physiological state of war! From a healthcare provider perspective, the word “shock” is associated with a mixed array of feelings, including dread, well-founded fear, and deep respect. The physiological state of shock is well recognized for the associated destructive consequences, and its successful management requires prompt identification, immediate action, and sustained effort by all members of the healthcare team. This mindset of advanced preparation and constant readiness constitutes the foundation of the modern approach toward shock – early detection and prompt treatment for optimal outcomes. Despite the heterogeneity of “shock” as a clinico-pathological entity, there are some common threads that permeate all forms and manifestations of shock, with apparent increase in observed commonalities in the more advanced (and often irreversible) stages of the systemic syndrome. When faced with shock, the body and its systems do their best to compensate for the maldistribution of oxygen and nutrients. This is known as the so-called compensated shock. Beyond that, the body loses its ability to adjust any further, thus descending into “uncompensated shock,” with a refractory state characterized by vasoplegia and irreversible cardiovascular failure. As the reader journeys through the chapters of the book, he or she will read about various biomarkers and endpoints of resuscitation, explore different types of shock (e.g., septic, hemorrhagic, anaphylactic) and learn about some of the less often discussed topics such as neurogenic and spinal shock, as well as the amniotic fluid embolism. Our goals were to keep things clinically relevant and practically oriented, thus enabling the reader to apply the newly acquired knowledge in their everyday clinical routines. As the reader progresses through the book, we hope to help stimulate further discourse and innovative thinking about the topic. In this context, it is critical that basic, translational, and clinical research on shock continues to advance. Only through ongoing scientific progress can we help improve outcomes for patients with both rare and common forms of shock.
Book Synopsis Hemodynamic Monitoring by : Michael R. Pinsky
Download or read book Hemodynamic Monitoring written by Michael R. Pinsky and published by Springer. This book was released on 2019-02-21 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, part of the European Society of Intensive Care Medicine textbook series, teaches readers how to use hemodynamic monitoring, an essential skill for today’s intensivists. It offers a valuable guide for beginners, as well as for experienced intensivists who want to hone their skills, helping both groups detect an inadequacy of perfusion and make the right choices to achieve the main goal of hemodynamic monitoring in the critically ill, i.e., to correctly assess the cardiovascular system and its response to tissue oxygen demands. The book is divided into distinguished sections: from physiology to pathophysiology; clinical assessment and measurements; and clinical practice achievements including techniques, the basic goals in clinical practice as well as the more appropriate hemodynamic therapy to be applied in different conditions. All chapters use a learning-oriented style, with practical examples, key points and take home messages, helping readers quickly absorb the content and, at the same time, apply what they have learned in the clinical setting. The European Society of Intensive Care Medicine has developed the Lessons from the ICU series with the vision of providing focused and state-of-the-art overviews of central topics in Intensive Care and optimal resources for clinicians working in Intensive Care.
Download or read book Sepsis written by Nicholas S. Ward and published by Humana Press. This book was released on 2017-05-29 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to provide a comprehensive and state-of-the-art resource for clinicians who care for patients with sepsis and research scientist alike, . Patients with severe sepsis requiring ICU admission have very high rates of ICU and overall hospital mortality, with estimates ranging from 18 to 50%. Risk factors for death from sepsis include underlying illness, increased age, and multi-system organ failure. This is compounded by the significant variation in the management of early severe sepsis. Care of these patients and clinical conditions can be quite complex, and materials are collected from the most current, evidence-based resources. Book sections have been structured to review the overall definitions and epidemiology of sepsis as well as current insights into the pathophysiology of sepsis. This review summarizes the evidence for the international consensus guidelines for the identification and management of sepsis. The latter part of this book reviews emerging concepts and approaches in the diagnosis and management of sepsis that may significantly reduce mortality in the future. Sepsis: Pathophysiology, Definitions and the Challenge of Bedside Management represents a collaboration between authors drawn from a variety of disciplines and contributions from basic scientists and highly recognized clinical opinion leaders with expertise in clinical trials.
Book Synopsis Sepsis: Strategies for Management by : Pablo Kennedy
Download or read book Sepsis: Strategies for Management written by Pablo Kennedy and published by . This book was released on 2022-09-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sepsis is a condition that occurs when the body's response to infection starts causing injury to its own organs and tissues. It may be life-threatening. The suppression of the immune system is the initial stage of sepsis. Common symptoms of sepsis are increased breathing rate, increased heart rate, fever and confusion. There can also be signs related to a specific infection such as painful urination with a kidney infection, cough with pneumonia, etc. If sepsis becomes severe, it can cause poor organ function or blood flow. The presence of low urine output, high blood lactate or low blood pressure is an indication of poor blood flow. This book brings forth some of the unexplored aspects of sepsis. The various studies that are constantly contributing towards advancing strategies for the management of sepsis are examined in detail. Those with an interest in this field would find this book helpful.
Download or read book Sepsis written by Konrad Reinhart and published by Springer. This book was released on 2012-02-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The comprehensive coverage of the incidence, etiology, pathophysiology, definition, and therapy of sepsis and septic shock gives you the knowledge you need to keep up with modern therapeutic strategies. The authors are either basic scientists or clinical researchers whose goal is to present the newest aspects of their work in comprehensible language. They clearly show the new perspectives that are emerging in the treatment of sepsis and septic shock.
Book Synopsis Clinical Fluid Therapy in the Perioperative Setting by : Robert G. Hahn
Download or read book Clinical Fluid Therapy in the Perioperative Setting written by Robert G. Hahn and published by Cambridge University Press. This book was released on 2016-05-26 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The world's most renowned researchers in fluid management explain what you should know when providing infusion fluids to surgical patients.
