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Author : Aliasghar Tabatabaei Mohammadi
Publisher : Nobel Sciences
ISBN 13 :
Total Pages : 68 pages
Book Rating : 4./5 ( download)
Download or read book New Frontiers in genetics and biology written by Aliasghar Tabatabaei Mohammadi and published by Nobel Sciences. This book was released on with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Andrew J. Wood
Publisher : Springer Science & Business Media
ISBN 13 : 0306485680
Total Pages : 208 pages
Book Rating : 4.3/5 (64 download)
Download or read book New Frontiers in Bryology written by Andrew J. Wood and published by Springer Science & Business Media. This book was released on 2013-03-20 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mosses (Bryophatea, Musci) are a diverse and widely distributed group of land plants. Mosses are attractive experimental plants because they exhibit the traditional attributes of good model systems (Le. ease of growth & maintenance, fast generation time, and amenable genetics) with the added advantage of a haploid gametophyte that allowed developmental mutants to be recovered with relative ease. In addition, mosses with the ability to tolerate extreme environmental conditions offer realistic models for the analysis of environmental stress-tolerance; particularly when compared to tracheophytes such as Arabidopsis thaliana in which these important plant phenotypes are either not clearly expressed or entirely lacking. And, in one of the most exciting developments in Plant Biology, efficient homologous recombination occurs in the moss Physcomitrella patens. The ability to perform efficient homologous recombination (Le. gene knock-outs) in P. patens is at present unique amongst all plants and represents an extremely powerful technique for the functional analysis of many plant genes. Over the past 5 years, a world-wide community of moss researchers has evolved. A highly successful "Moss" conference has been held annually (l998-Mumbai, India; 1999-Carbondale, IL, USA; 2000-Villars, Switzerland; 200l-0kazaki, Japan; 2002-Ambleside, UK; 2003-St. Louis, MO, USA) with "Moss 2004" planned to be held in Frieburg Germany. These conferences have been instrumental in the creation & development of strong collaborative ties, and the free exchange of both ideas and materials.
Author : Vijai Singh
Publisher : Academic Press
ISBN 13 : 0323859860
Total Pages : 487 pages
Book Rating : 4.3/5 (238 download)
Download or read book New Frontiers and Applications of Synthetic Biology written by Vijai Singh and published by Academic Press. This book was released on 2022-01-12 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Frontiers and Applications of Synthetic Biology presents a collection of chapters from eminent synthetic biologists across the globe who have established experience and expertise working with synthetic biology. This book offers several important areas of synthetic biology which allow us to read and understand easily. It covers the introduction of synthetic biology and design of promoter, new DNA synthesis and sequencing technology, genome assembly, minimal cells, small synthetic RNA, directed evolution, protein engineering, computational tools, de novo synthesis, phage engineering, a sensor for microorganisms, next-generation diagnostic tools, CRISPR-Cas systems, and more. This book is a good source for not only researchers in designing synthetic biology, but also for researchers, students, synthetic biologists, metabolic engineers, genome engineers, clinicians, industrialists, stakeholders and policymakers interested in harnessing the potential of synthetic biology in many areas. - Offers basic understanding and knowledge in several aspects of synthetic biology - Covers state-of-the-art tools and technologies of synthetic biology, including promoter design, DNA synthesis, DNA sequencing, genome design, directed evolution, protein engineering, computational tools, phage design, CRISPR-Cas systems, and more - Discusses the applications of synthetic biology for smart drugs, vaccines, therapeutics, drug discovery, self-assembled materials, cell free systems, microfluidics, and more
Author : Hilary Rose
Publisher : Verso Books
ISBN 13 : 178168314X
Total Pages : 353 pages
Book Rating : 4.7/5 (816 download)
Download or read book Genes, Cells, and Brains written by Hilary Rose and published by Verso Books. This book was released on 2014-04-08 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our fates lie in our genes and not in the stars, said James Watson, co-discoverer of the structure of DNA. But Watson could not have predicted the scale of the industry now dedicated to this new frontier. Since the launch of the multibillion-dollar Human Genome Project, the biosciences have promised miraculous cures and radical new ways of understanding who we are. But where is the new world we were promised? Now updated with a new afterword, Genes, Cells and Brains asks why the promised cornucopia of health benefits has failed to emerge and reveals the questionable enterprise that has grown out of bioethics. The authors, feminist sociologist Hilary Rose and neuroscientist Steven Rose, examine the establishment of biobanks, the rivalries between public and private gene sequencers, and the rise of stem cell research. The human body is becoming a commodity, and the unfulfilled promises of the science behind this revolution suggest profound failings in genomics itself.
Author : Jean Hamburger
Publisher : W. W. Norton
ISBN 13 :
Total Pages : 136 pages
Book Rating : 4.3/5 (91 download)
Download or read book Discovering the Individual written by Jean Hamburger and published by W. W. Norton. This book was released on 1978 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Yuan-Ming Zhang
Publisher : Frontiers Media SA
ISBN 13 : 2889458342
Total Pages : 236 pages
Book Rating : 4.8/5 (894 download)
Download or read book The Applications of New Multi-Locus GWAS Methodologies in the Genetic Dissection of Complex Traits written by Yuan-Ming Zhang and published by Frontiers Media SA. This book was released on 2019-06-19 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome-Wide Association Studies (GWAS) are widely used in the genetic dissection of complex traits. Most existing methods are based on single-marker association in genome-wide scans with population structure and polygenic background controls. To control the false positive rate, the Bonferroni correction for multiple tests is frequently adopted. This stringent correction results in the exclusion of important loci, especially for GWAS in crop genetics. To address this issue, multi-locus GWAS methodologies have been recommended, i.e., FASTmrEMMA, ISIS EM-BLASSO, mrMLM, FASTmrMLM, pLARmEB, pKWmEB and FarmCPU. In this Research Topic, our purpose is to clarify some important issues in the application of multi-locus GWAS methods. Here we discuss the following subjects: First, we discuss the advantages of new multi-locus GWAS methods over the widely-used single-locus GWAS methods in the genetic dissection of complex traits, metabolites and gene expression levels. Secondly, large experiment error in the field measurement of phenotypic values for complex traits in crop genetics results in relatively large P-values in GWAS, indicating the existence of small number of significantly associated SNPs. To solve this issue, a less stringent P-value critical value is often adopted, i.e., 0.001, 0.0001 and 1/m (m is the number of markers). Although lowering the stringency with which an association is made could identify more hits, confidence in these hits would significantly drop. In this Research Topic we propose a new threshold of significant QTN (LOD=3.0 or P-value=2.0e-4) in multi-locus GWAS to balance high power and low false positive rate. Thirdly, heritability missing in GWAS is a common phenomenon, and a series of scientists have explained the reasons why the heritability is missing. In this Research Topic, we also add one additional reason and propose the joint use of several GWAS methodologies to capture more QTNs. Thus, overall estimated heritability would be increased. Finally, we discuss how to select and use these multi-locus GWAS methods.
Author : Jianfeng Feng
Publisher : Springer Science & Business Media
ISBN 13 : 1849961964
Total Pages : 411 pages
Book Rating : 4.8/5 (499 download)
Download or read book Frontiers in Computational and Systems Biology written by Jianfeng Feng and published by Springer Science & Business Media. This book was released on 2010-06-14 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological and biomedical studies have entered a new era over the past two decades thanks to the wide use of mathematical models and computational approaches. A booming of computational biology, which sheerly was a theoretician’s fantasy twenty years ago, has become a reality. Obsession with computational biology and theoretical approaches is evidenced in articles hailing the arrival of what are va- ously called quantitative biology, bioinformatics, theoretical biology, and systems biology. New technologies and data resources in genetics, such as the International HapMap project, enable large-scale studies, such as genome-wide association st- ies, which could potentially identify most common genetic variants as well as rare variants of the human DNA that may alter individual’s susceptibility to disease and the response to medical treatment. Meanwhile the multi-electrode recording from behaving animals makes it feasible to control the animal mental activity, which could potentially lead to the development of useful brain–machine interfaces. - bracing the sheer volume of genetic, genomic, and other type of data, an essential approach is, ?rst of all, to avoid drowning the true signal in the data. It has been witnessed that theoretical approach to biology has emerged as a powerful and st- ulating research paradigm in biological studies, which in turn leads to a new - search paradigm in mathematics, physics, and computer science and moves forward with the interplays among experimental studies and outcomes, simulation studies, and theoretical investigations.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309070864
Total Pages : 348 pages
Book Rating : 4.3/5 (9 download)
Download or read book Scientific Frontiers in Developmental Toxicology and Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 2000-12-21 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.
Author :
Publisher : National Academies
ISBN 13 :
Total Pages : 552 pages
Book Rating : 4.1/5 (36 download)
Download or read book The Life Sciences written by and published by National Academies. This book was released on 1970-01-01 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : V. L. Chopra
Publisher :
ISBN 13 : 9780859350686
Total Pages : 309 pages
Book Rating : 4.3/5 (56 download)
Download or read book Genetics written by V. L. Chopra and published by . This book was released on 1984 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Serge Morand
Publisher : Springer Science & Business Media
ISBN 13 : 9400721145
Total Pages : 335 pages
Book Rating : 4.4/5 (7 download)
Download or read book New Frontiers of Molecular Epidemiology of Infectious Diseases written by Serge Morand and published by Springer Science & Business Media. This book was released on 2011-09-08 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular epidemiology has recently broaden its focuses due to the development of molecular tools but also by incorporating advances of other fields such as mathematical epidemiology, molecular ecology, population genetics and evolution. Facing new risks of emerging and re-emerging infectious diseases that are threats for humans and their livestock, the objectives of molecular epidemiology include: - the development of molecular tools, genotyping and gene expression - the incorporation of concepts and results of population genetics of infectious diseases - the integration of recent advances in theoretical epidemiology and evolutionary ecology of diseases - a better understanding of transmission for the development of risk factors analyses. This book will demonstrate how the latest developments in molecular tools and in epidemiology can be integrated with studies of host-pathogen interactions. Besides a strong theoretical component, there will also be an emphasis on applications in the fields of epidemiology, public health, veterinary medicine, and health ecology. Students and researchers in the fields of epidemiology, animal and human health, evolutionary ecology, parasitology are the main potential readers of the book, as well as a broader audience from veterinary medicine and conservation.
Download or read book Genetics, New Frontiers: Genetic organization, function, and regulation written by and published by . This book was released on 1984 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kaja Finkler
Publisher :
ISBN 13 :
Total Pages : 304 pages
Book Rating : 4.3/5 (91 download)
Download or read book Experiencing the New Genetics written by Kaja Finkler and published by . This book was released on 2000 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experiencing the New Genetics will lead scholars and general readers alike to question how far genetic inheritance affects our selves and our future.
Author : Hemin R Chin
Publisher : CRC Press
ISBN 13 : 9780367455132
Total Pages : 360 pages
Book Rating : 4.4/5 (551 download)
Download or read book Methods in Genomic Neuroscience written by Hemin R Chin and published by CRC Press. This book was released on 2019-12-18 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authored by researchers in the forefront of the field, this book provides a guide for applying powerful molecular genetic techniques to the study of neural and behavioral systems. It supplies a foundation by which data on gene expression and function may be used to develop new therapeutic strategies for brain diseases. The book covers tools and tec
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 9780309087278
Total Pages : 190 pages
Book Rating : 4.0/5 (872 download)
Download or read book Frontiers in Polar Biology in the Genomic Era written by National Research Council and published by National Academies Press. This book was released on 2003-08-08 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: As we enter the twenty-first century, the polar biological sciences stand well poised to address numerous important issues, many of which were unrecognized as little as 10 years ago. From the effects of global warming on polar organisms to the potential for life in subglacial Lake Vostok, the opportunities to advance our understanding of polar ecosystems are unprecedented. The era of "genome-enabled" biology is upon us, and new technologies will allow us to examine polar biological questions of unprecedented scope and to do so with extraordinary depth and precision. Frontiers in Polar Biology in the Genomic Revolution highlights research areas in polar biology that can benefit from genomic technologies and assesses the impediments to the conduct of polar genomic research. It also emphasizes the importance of ancillary technologies to the successful application of genomic technologies to polar studies. It recommends the development of a new initiative in polar genome sciences that emphasizes collaborative multidisciplinary research to facilitate genome analyses of polar organisms and coordinate research efforts.
Author : Thomas F. Kresina
Publisher : John Wiley & Sons
ISBN 13 : 0471461040
Total Pages : 408 pages
Book Rating : 4.4/5 (714 download)
Download or read book An Introduction to Molecular Medicine and Gene Therapy written by Thomas F. Kresina and published by John Wiley & Sons. This book was released on 2004-03-24 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction to Molecular Medicine and Gene Therapy Edited by Thomas F. Kresina, Ph.D. Gene therapy, or the use of genetic manipulation for disease treatment, is derived from advances in genetics, molecular biology, clinical medicine, and human genomics. Molecular medicine, the application of molecular biological techniques to disease treatment and diagnosis, is derived from the development of human organ transplantation, pharmacotherapy, and elucidation of the human genome. An Introduction to Molecular Medicine and Gene Therapy provides a basis for interpreting new clinical and basic research findings in the areas of cloning, gene transfer, and targeting; the applications of genetic medicine to clinical conditions; ethics and governmental regulations; and the burgeoning fields of genomics, biotechnology, and bioinformatics. By dividing the material into three sections - an introduction to basic science, a review of clinical applications, and a discussion of the evolving issues related to gene therapy and molecular medicine-this comprehensive manual describes the basic approaches to the broad range of actual and potential genetic-based therapies. In addition, An Introduction to Molecular Medicine and Gene Therapy: * Covers new frontiers in gene therapy, animal models, vectors, gene targeting, and ethical/legal considerations * Provides organ-based reviews of current studies in gene therapy for monogenetic, multifactoral or polygenic disorders, and infectious diseases * Includes bold-faced terms, key concepts, summaries, and lists of helpful references by subject in each chapter * Contains appendices on commercial implications and a review of the history of gene therapy This textbook offers a clear, concise writing style, drawing upon the expertise of the authors, all renowned researchers in their respective specialties of molecular medicine. Researchers in genetics and molecular medicine will all find An Introduction to Molecular Medicine and Gene Therapy to be an essential guide to the rapidly evolving field of gene therapy and its applications in molecular medicine.
Author : Clay Carter
Publisher : Frontiers Media SA
ISBN 13 : 2889459969
Total Pages : 262 pages
Book Rating : 4.8/5 (894 download)
Download or read book New Perspectives on the Biology of Nectaries and Nectars written by Clay Carter and published by Frontiers Media SA. This book was released on 2019-08-27 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: The number of currently known, described and accepted plant species is ca 374,000, of which approximately 295,00 (79%) are angiosperms. Almost 90% of this huge number of flowering plants is pollinated by animals (mostly insects) via nectar-mediated interactions. Notably, three-fourths of the leading global crop plants produce nectar and are animal pollinated, which is estimated to account for one-third of human food resources. Nectar can also be produced on tissues outside of flowers, by so-called extrafloral nectaries, and commonly mediate interactions with ‘body-guard’ ants and other pugnacious insects that defend the plant from herbivores. Extrafloral nectar is present in almost 4,000 plant species, a majority of them in the angiosperms. This brief summary on the occurrence of nectar in the plant kingdom is just to highlight that nectar has a fundamental role in two basal functions that allow the maintenance of our ecosystems: sexual plant reproduction and protection of plants from herbivory. Despite playing essential ecological and evolutionary functions, our current knowledge about nectar is largely incomplete; however, new research directions and perspectives on nectaries and nectars have arisen in recent years. In the last two decades, there were only a few ‘moments’ in which nectar was the main character in international meetings or in published books. In 2002, the first (and only) international meeting “Nectar and nectary: from biology to biotechnology” dedicated exclusively to nectar and nectaries was held in Italy (Montalcino, Siena) and in 2003 the proceedings were published in a special volume of Plant Systematics and Evolution (238, issue 1-4). In 2007, the book Nectar and Nectaries was published (Springer) with most of the contributions provided by authors that attended the meeting in Italy. Another book dedicated to nectar was published in 2015 (Nectar: Production, Chemical Composition and Benefits to Animals and Plants, Nova Science Publishers) covering aspects mainly related to nectar chemical composition and plant-pollinator interactions. Similarly, symposia focused on nectar have been organized within the International Botanical Congress in 2011 and 2017. Considering that the last few years has yielded essential developments in the understanding of nectar biology, we thought now is the moment to further stimulate research on this important topic. This aim has been met through 18 papers published in our Research Topic New Perspectives on the Biology of Nectaries and Nectars, with subjects spanning evolution and ecology to nectar chemistry and nectary structure.
