Author : W. Hiddemann
Publisher : Springer Science & Business Media
ISBN 13 : 3642757200
Total Pages : 59 pages
Book Rating : 4.6/5 (427 download)
Book Synopsis New Findings on Aclarubicin in the Treatment of Acute Myeloid Leukemia by : W. Hiddemann
Download or read book New Findings on Aclarubicin in the Treatment of Acute Myeloid Leukemia written by W. Hiddemann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 59 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the introduction of new anthracycline derivatives and anthrachi none analogues a few years ago, aclacinomycin A (Aclarubicin) has become an established agent for the treatment of hematologic malig nancies. A special symposium was therefore held during the congress of the German Society of Hermatology and Oncology in Hannover in October 1989 to provide an up-to-date overv.iew. Leading experts from the United States, Sweden, and Germany reported on the results being obtained with aclacinomycin A, alone or combined with other agents, in patients with acute leukemias and myelodysplastic syndromes. This book is based on their contributions. As regards single-agent treatment, aclacinomycin A in myelodys plastic syndromes is dealt with, as well as its application in older patients with acute myeloid leukemia. Four contributions are devoted to the use of aclacinomycin A in combination with conventional or intermediate dose cytosine arabinoside or etoposide in patients with relapsed or refractory acute myeloid leukemia. The results reported indicate that aclacinomycin A has substantial activity in the treatment of hematologic malignancies. In summary, this book provides a valuable update on the current status of aclacinomycin A as used by experts in the treatment of he matologic malignancies.