New Findings on Aclarubicin in the Treatment of Acute Myeloid Leukemia

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Publisher : Springer Science & Business Media
ISBN 13 : 3642757200
Total Pages : 59 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis New Findings on Aclarubicin in the Treatment of Acute Myeloid Leukemia by : W. Hiddemann

Download or read book New Findings on Aclarubicin in the Treatment of Acute Myeloid Leukemia written by W. Hiddemann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 59 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the introduction of new anthracycline derivatives and anthrachi none analogues a few years ago, aclacinomycin A (Aclarubicin) has become an established agent for the treatment of hematologic malig nancies. A special symposium was therefore held during the congress of the German Society of Hermatology and Oncology in Hannover in October 1989 to provide an up-to-date overv.iew. Leading experts from the United States, Sweden, and Germany reported on the results being obtained with aclacinomycin A, alone or combined with other agents, in patients with acute leukemias and myelodysplastic syndromes. This book is based on their contributions. As regards single-agent treatment, aclacinomycin A in myelodys plastic syndromes is dealt with, as well as its application in older patients with acute myeloid leukemia. Four contributions are devoted to the use of aclacinomycin A in combination with conventional or intermediate dose cytosine arabinoside or etoposide in patients with relapsed or refractory acute myeloid leukemia. The results reported indicate that aclacinomycin A has substantial activity in the treatment of hematologic malignancies. In summary, this book provides a valuable update on the current status of aclacinomycin A as used by experts in the treatment of he matologic malignancies.

New Findings on Aclarubicin in the Treatment of Acute Myeloid Leukemia

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Author :
Publisher : Springer Verlag
ISBN 13 : 9780387526133
Total Pages : 52 pages
Book Rating : 4.5/5 (261 download)

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Book Synopsis New Findings on Aclarubicin in the Treatment of Acute Myeloid Leukemia by : W. Hiddemann

Download or read book New Findings on Aclarubicin in the Treatment of Acute Myeloid Leukemia written by W. Hiddemann and published by Springer Verlag. This book was released on 1990-01-01 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Medicinal Chemistry of Anticancer Drugs

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Publisher : Elsevier
ISBN 13 : 0444626670
Total Pages : 767 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Medicinal Chemistry of Anticancer Drugs by : Carmen Avendaño

Download or read book Medicinal Chemistry of Anticancer Drugs written by Carmen Avendaño and published by Elsevier. This book was released on 2015-06-11 with total page 767 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While these therapies are in their infancy, they hold promise of more effective therapies with fewer side effects. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a sorely needed update from the point of view of medicinal chemistry and drug design. - Presents information in a clear and concise way using a large number of figures - Historical background provides insights on how the process of drug discovery in the anticancer field has evolved - Extensive references to primary literature

Razoxane and Dexrazoxane - Two Multifunctional Agents

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Publisher : Springer Science & Business Media
ISBN 13 : 9048191688
Total Pages : 252 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis Razoxane and Dexrazoxane - Two Multifunctional Agents by : Walter Rhomberg

Download or read book Razoxane and Dexrazoxane - Two Multifunctional Agents written by Walter Rhomberg and published by Springer Science & Business Media. This book was released on 2010-08-03 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Razoxane and dexrazoxane are two novel drugs with some uniquely useful features. They block cell division at the G2/M border, but nowhere else, so that they have a low toxicity profile. They suppress tumor metastasis and haemorrhages through normalization of pathological blood vessels. Razoxane potentiates radiotherapy especially in the treatment of soft tissue sarcomas and gastrointestinal neoplasms. They protect normal tissues against toxic chemicals, e.g. the myocardium against anthracyclines or subcutaneous tissue against injuries caused by incidental extravasations of anthracyclines. Dexrazoxane is the only drug approved by the FDA/EMEA for the specific purpose of preventing cardiac damage when giving the widely used and effective antitumor anthracyclines. The reduction of cardiotoxicity is achieved without response reduction or reducing of time to progression of tumors. While the full analysis of their actions at the molecular level is not yet completely understood, it seems most likely that it is via an inhibition on the topoisomerase II a. Moreover, the drugs have the ability to chelate several metals including iron, copper or zinc. The protection of normal tissues is nowhere more important than that of brain, and there are indications that the proteins thought to be responsible for the ravages of Alzheimer ́s disease could be stabilized by one or both these drugs.

Allogeneic Stem Cell Transplantation

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Publisher : Springer Science & Business Media
ISBN 13 : 1597454788
Total Pages : 885 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Allogeneic Stem Cell Transplantation by : Hillard M. Lazarus

Download or read book Allogeneic Stem Cell Transplantation written by Hillard M. Lazarus and published by Springer Science & Business Media. This book was released on 2010-03-02 with total page 885 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.

Cancer Treatment Reports

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Publisher :
ISBN 13 :
Total Pages : 706 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Cancer Treatment Reports by :

Download or read book Cancer Treatment Reports written by and published by . This book was released on 1987 with total page 706 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genomic and Precision Medicine

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Publisher : Academic Press
ISBN 13 : 0128006536
Total Pages : 379 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Genomic and Precision Medicine by : Geoffrey S. Ginsburg

Download or read book Genomic and Precision Medicine written by Geoffrey S. Ginsburg and published by Academic Press. This book was released on 2022-04-09 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomic and Precision Medicine: Oncology, Third Edition focuses on the applications of genome discovery as research points to personalized cancer therapies. Each chapter is organized to cover the application of genomics and personalized medicine tools and technologies to a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precision Therapeutics, and d) Emerging and Future Opportunities in the field. - Provides a comprehensive volume written and edited by oncology genomic specialists for oncology health providers - Includes succinct commentary and key learning points that will assist providers with their local needs for implementation of genomic and personalized medicine into practice - Presents an up-to-date overview on major opportunities for genomic and personalized medicine in practice - Covers case studies that highlight the practical use of genomics in the management of patients

AML in the Molecular Age: From Biology to Clinical Management

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Publisher : MDPI
ISBN 13 : 3038972800
Total Pages : 209 pages
Book Rating : 4.0/5 (389 download)

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Book Synopsis AML in the Molecular Age: From Biology to Clinical Management by : Celalettin Ustun

Download or read book AML in the Molecular Age: From Biology to Clinical Management written by Celalettin Ustun and published by MDPI. This book was released on 2018-10-12 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "AML in the Molecular Age: From Biology to Clinical Management" that was published in JCM

National Library of Medicine Current Catalog

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Publisher :
ISBN 13 :
Total Pages : 968 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis National Library of Medicine Current Catalog by : National Library of Medicine (U.S.)

Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1991 with total page 968 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cumulated Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 1092 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1983 with total page 1092 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cytotoxins and Immunotoxins for Cancer Therapy

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Publisher : CRC Press
ISBN 13 : 0203303164
Total Pages : 242 pages
Book Rating : 4.2/5 (33 download)

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Book Synopsis Cytotoxins and Immunotoxins for Cancer Therapy by : Koji Kawakami

Download or read book Cytotoxins and Immunotoxins for Cancer Therapy written by Koji Kawakami and published by CRC Press. This book was released on 2004-11-15 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in cytotoxins and immunotoxins are accelerating our understanding of cancer and leading to more effective therapeutic treatments. Although a large number of articles have been published on these cytotoxins and immunotoxins, this important information has yet to be compiled into one comprehensive resource. For the first time,

Current Catalog

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Publisher :
ISBN 13 :
Total Pages : 524 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Current Catalog by : National Library of Medicine (U.S.)

Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1991 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.

Drug Repurposing in Neurodegenerative and Neuropsychiatric Disorders

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889741680
Total Pages : 337 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Drug Repurposing in Neurodegenerative and Neuropsychiatric Disorders by : Anna R. Carta

Download or read book Drug Repurposing in Neurodegenerative and Neuropsychiatric Disorders written by Anna R. Carta and published by Frontiers Media SA. This book was released on 2022-01-25 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mechanisms of Epigenetics and Genetics in Leukemogenesis

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Publisher : Frontiers Media SA
ISBN 13 : 2889760405
Total Pages : 134 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Mechanisms of Epigenetics and Genetics in Leukemogenesis by : Yonghui Li

Download or read book Mechanisms of Epigenetics and Genetics in Leukemogenesis written by Yonghui Li and published by Frontiers Media SA. This book was released on 2022-04-29 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Spinal Muscular Atrophy

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Publisher : Academic Press
ISBN 13 : 0128036869
Total Pages : 508 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Spinal Muscular Atrophy by : Charlotte J Sumner

Download or read book Spinal Muscular Atrophy written by Charlotte J Sumner and published by Academic Press. This book was released on 2016-10-24 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spinal Muscular Atrophy: Disease Mechanisms and Therapy provides the latest information on a condition that is characterized by motoneuron loss and muscle atrophy, and is the leading genetic cause of infant mortality. Since the identification of the gene responsible for SMA in 1995, there have been important advances in the basic understanding of disease mechanisms, and in therapeutic development. This book provides a comprehensive accounting of recent advances in basic and clinical research that covers SMA clinical features and standards of care, multifaceted aspects of SMN protein functions and SMA disease pathology, various animal models, and biomarkers, as well as current therapeutic development. This title is ideal for graduate students/postdocs and principal investigators who are already in the SMA field and need to keep updated on recent findings and approaches, and for those who are new to, or would like to join, the field. Likewise, users will find an excellent source of reading for biotech/pharma scientists, clinical researchers, and practitioners, regulators, and patients and their advocacy organizations. Furthermore, this book is a handy reference for researchers and clinicians who may want to apply the research strategies and therapeutic approaches in SMA to other rare diseases. - Provides comprehensive, up-to-date reviews by leading investigators on diverse topics of SMA, including clinical features and patient care, SMN genetics and protein functions, animal models, disease pathology and mechanisms, biomarkers, current therapeutic development, and the role of non-profit organizations in therapeutic development - Written to bridge multiple disciplines and promote better communications among basic scientists, clinical researchers, and health care providers on the latest developments in SMA - Includes outstanding questions and perspectives for future investigations and key references for additional detailed study

Subject Guide to Books in Print

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Publisher :
ISBN 13 :
Total Pages : 2476 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Subject Guide to Books in Print by :

Download or read book Subject Guide to Books in Print written by and published by . This book was released on 1996 with total page 2476 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Diagnostic and Therapeutic Advances in Hematologic Malignancies

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Publisher : Springer Science & Business Media
ISBN 13 : 0585385718
Total Pages : 383 pages
Book Rating : 4.5/5 (853 download)

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Book Synopsis Diagnostic and Therapeutic Advances in Hematologic Malignancies by : Martin S. Tallman

Download or read book Diagnostic and Therapeutic Advances in Hematologic Malignancies written by Martin S. Tallman and published by Springer Science & Business Media. This book was released on 2007-11-23 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is no field of medicine in which advances in therapy have been so closely linked to a better understanding of molecular medicine than in the area of hematologic malignancies. Diagnostic and Therapeutic Advances in Hematologic Malignancies will provide practitioners and academic clinicians with a better understanding of the constant evolving concepts in this area.