New Bioactive Surfaces For Titanium Implants

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New Bioactive Surfaces for Titanium Implants

Author : Laëtitia Salou
Publisher :
ISBN 13 :
Total Pages : 212 pages
Book Rating : 4.:/5 (124 download)

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Book Synopsis New Bioactive Surfaces for Titanium Implants by : Laëtitia Salou

Download or read book New Bioactive Surfaces for Titanium Implants written by Laëtitia Salou and published by . This book was released on 2015 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biocompatible and corrosion resistant regarding biological fluids, titanium is still an inert material: it does not participate actively at the tissue-integration around the implant. Surface modification of titanium at nanoscale can promote cell adhesion and differentiation by modulate genes expression due to a phenomenon of mechano-transduction. In this thesis, we have focused on the development, the characterization and the direct application of our nanostructured surface of medical devices. First of all, our study focused on the preparation and physicochemical characterization. After obtaining reproducible surfaces on small samples, our research has focused on the biological characterization of the surface. In-vivo studies conducted in rabbits have allowed us to show similar biomechanical attachment and good osseointegration of the nanostructured surface compared to commonly used surfaces on the market. The application of this new surface on more complex titanium implant such as tracheal prosthesis, has allowed us to observe delamination phenomenon of the nanostructure layer. Therefore, our research was oriented towards the problem of mechanical strength of the surface with the realization of nano scratch test and tribology. A topic in the zeitgeist, as a new EU regulation for medical devices which incorporate nanomaterials will take effect in 2017. To conclude, this work enable to propose a nanosurface with promising results of tissues integration required for medical device.

Modification of Titanium to Generate Biocompatible and Bioactive Implant Surfaces

Author : Nina Adden
Publisher :
ISBN 13 :
Total Pages : 130 pages
Book Rating : 4.:/5 (246 download)

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Book Synopsis Modification of Titanium to Generate Biocompatible and Bioactive Implant Surfaces by : Nina Adden

Download or read book Modification of Titanium to Generate Biocompatible and Bioactive Implant Surfaces written by Nina Adden and published by . This book was released on 2006 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bioscience and Bioengineering of Titanium Materials

Author : Yoshiki Oshida
Publisher : Elsevier
ISBN 13 : 0080467199
Total Pages : 447 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Bioscience and Bioengineering of Titanium Materials by : Yoshiki Oshida

Download or read book Bioscience and Bioengineering of Titanium Materials written by Yoshiki Oshida and published by Elsevier. This book was released on 2010-07-07 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book about bioscience and the bioengineering of titanium materials is based on more than 1,000 published articles. It bridges the gap between the medical/dental fields and the engineering/technology areas, due to the author’s unique experience in both during the last 30 years. The book covers Materials Classifications, Chemical and Electrochemical Reactions, Oxidation, Biological Reactions, Implant-related Biological Reactions, Applications, Fabri-cation Technologies, Surface Modifications, and Future Perspectives. * Provides quick access to the primary literature in this field* Reviews studies of titanium materials in medical and dental applications, as reported in nearly 1,500 articles published over last several years* Draws information from several types of studies and reports* Helps readers answer questions about the most appropriate materials and when to use them

Titanium in Medicine

Author : D.M. Brunette
Publisher : Springer Science & Business Media
ISBN 13 : 3642564860
Total Pages : 1019 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Titanium in Medicine by : D.M. Brunette

Download or read book Titanium in Medicine written by D.M. Brunette and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 1019 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing scientific and technical in-depth information in a clear format with a homogeneous structure, this text is suited for educational and self-teaching purposes as well as a reference on titanium for biomedical applications. It covers the whole area relevant to the use of titanium for implants, devices and instruments in medicine: material and surface science, physics, chemistry, biology, medicine, quality and regulatory aspects.

Biological Responses of Fibroblasts and Osteoblasts on Modified Bioactive Titanium Implant Surfaces

Author : Mariana Cruz
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (116 download)

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Book Synopsis Biological Responses of Fibroblasts and Osteoblasts on Modified Bioactive Titanium Implant Surfaces by : Mariana Cruz

Download or read book Biological Responses of Fibroblasts and Osteoblasts on Modified Bioactive Titanium Implant Surfaces written by Mariana Cruz and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Background: Calcium-phosphate bioactive coatings have been suggested to improve the biological response of titanium. We have developed a new manufacturing protocol that enables integration of these bioactive materials in a titanium scaffold, overcoming the mechanical limitations of coatings. However, the biological behavior of these new materials is not yet described. Objectives: The aim of this study was to evaluate the behavior of human fetal osteoblasts and human gingival fibroblasts in contact with Titanium (Ti), Ti with 5% hydroxyapatite (TiHA) or Ti with 5% beta tricalcium phosphate (Ti-bTCP). Materials and methods: Ti, TiHA and Ti-bTCP discs were produced with homogeneous surface roughness. Human fetal osteoblasts and human gingival fibroblasts were cultured on discs for 14 days using previously established methods. Morphology and cellular adhesion were analyzed using scanning electron microscopy (SEM) after 1 and 7 days. Cell viability and proliferation were evaluated at pre-defined time-points (1,3,7 and 14 days) using a commercial resazurin-based method. Alkaline phosphatase (ALP) activity was evaluated at 7 and 14 days for osteoblasts. All results were presented as mean fluorescence intensity (AU) u00b1 standard deviation (SD). Mineralization patterns were evaluated using hydroxyapatite fluorescence staining. Group comparisons were tested using Anova (Tukeyu2019s post-hoc) using appropriate statistical software and significance was set p

Surface Modification of Titanium Implants by Grit-blasting with Novel Bioactive Glasses

Author : Farah Nabeel Mohammed Tahir Al-Khayyat
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (19 download)

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Book Synopsis Surface Modification of Titanium Implants by Grit-blasting with Novel Bioactive Glasses by : Farah Nabeel Mohammed Tahir Al-Khayyat

Download or read book Surface Modification of Titanium Implants by Grit-blasting with Novel Bioactive Glasses written by Farah Nabeel Mohammed Tahir Al-Khayyat and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Surface Modification of Titanium Dental Implants

Author : Karan Gulati
Publisher : Springer Nature
ISBN 13 : 3031215656
Total Pages : 259 pages
Book Rating : 4.0/5 (312 download)

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Book Synopsis Surface Modification of Titanium Dental Implants by : Karan Gulati

Download or read book Surface Modification of Titanium Dental Implants written by Karan Gulati and published by Springer Nature. This book was released on 2023-02-27 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive technical and scientific overview of the surface modification of titanium dental implants. Coverage ranges from basic concepts of surface modification to advanced micro- and nano-engineering strategies employed to achieve augmented bioactivity to meet the needs of compromised patient conditions. A special focus of the book is advanced state-of-the-art electrochemically anodized nanostructures fabricated on implants towards enhanced bioactivity and local therapy. Surface Modification of Titanium Dental Implants will keep you current in the domain of titanium dental implants and will provide an improved understanding of their performance and application. The book will benefit engineers, clinicians, and researchers in biomaterials, biomedical engineering, dental and bone implants, nano-engineering, and technology.

On Possibly Bioactive CP Titanium Implant Surfaces

Author : Anna Göransson
Publisher :
ISBN 13 : 9789162870058
Total Pages : 101 pages
Book Rating : 4.8/5 (7 download)

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Book Synopsis On Possibly Bioactive CP Titanium Implant Surfaces by : Anna Göransson

Download or read book On Possibly Bioactive CP Titanium Implant Surfaces written by Anna Göransson and published by . This book was released on 2006 with total page 101 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Calcium Phosphate Biomaterials

Author : Besim Ben-Nissan
Publisher : Springer Science & Business
ISBN 13 : 3642539807
Total Pages : 559 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Advances in Calcium Phosphate Biomaterials by : Besim Ben-Nissan

Download or read book Advances in Calcium Phosphate Biomaterials written by Besim Ben-Nissan and published by Springer Science & Business. This book was released on 2014-04-17 with total page 559 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Calcium Phosphate Biomaterials presents a comprehensive, state-of-the-art review of the latest advances in developing calcium phosphate biomaterials and their applications in medicine. It covers the fundamental structures, synthesis methods, characterization methods, and the physical and chemical properties of calcium phosphate biomaterials, as well as the synthesis and properties of calcium phosphate-based biomaterials in regenerative medicine and their clinical applications. The book brings together these new concepts, mechanisms and methods in contributions by both young and “veteran” academics, clinicians, and researchers to forward the knowledge and expertise on calcium phosphate and related materials. Accordingly, the book not only covers the fundamentals but also open new avenues for meeting future challenges in research and clinical applications. Besim Ben-Nissan is a Professor of Chemistry and Forensic Science at the University of Technology, Sydney, Australia

Phytic Acid Calcium Hydroxide Composite Coating on Titanium Implants Promote Early Osseointegration

Author : Hao Zhang
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (116 download)

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Book Synopsis Phytic Acid Calcium Hydroxide Composite Coating on Titanium Implants Promote Early Osseointegration by : Hao Zhang

Download or read book Phytic Acid Calcium Hydroxide Composite Coating on Titanium Implants Promote Early Osseointegration written by Hao Zhang and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract:Titanium surfaces have been constantly modified to improve bioactivity and osseointegration. In this study, we modified titanium surfaces through hydrothermal treatment with a mixed solution of phytic acid and calcium hydroxide, then evaluated their bioactive and osteogenic activities. In vitro tests, calcium-decorated titanium surface enhanced the cell adhesion, proliferation and osteogenic differentiation of human bone marrow mesenchymal stem cells (hBMSCs). In vivo tests, Micro- CT and histological evaluations indicated that the modified implants promoted new bone formation and osseointegration between the implants and the host bone. These findings provided evidence that this simple modification would be promising solution to improve bioactivity and osseointegration, which would be beneficial not only for titanium implants but also other implanted biomaterials.Background: Titanium (Ti) or titanium alloys coated with various bioactive calcium phosphates (CaPs), including hydroxyapatite (HA) and u03b2-tricalcium phosphate (u03b2-TCP), are considered as satisfactory implant materials. CaP coatings provide nanostructural or microstructuctural characteristics on titanium or titanium alloys, thereby increasing the adhesion of osteoblasts, which enhance the osseointegration and shorten the healing time.Aim: To prepare and evaluate the effect of calcium-containing chemical conversion coating on promoting new bone formation and early osseointegration in vivo.Material and methods: We designed and prepared a phytic acid/calcium hydroxide composite coating on the pure titanium implant (Ti-SLA-2/10) through hydrothermal treatment with a mixed solution of phytic acid (PA) and saturated calcium hydroxide solution [Ca (OH)2]. The pure titanium implant with a sandblasted/acid-etched (SLA) surface was used as the control group (Ti-SLA). The surface morphology, elemental composition, surface roughness, wettability, and calcium ion release were investigated separately. Twenty-four SLA and calcium-containing SLA implants were immediately inserted into the mandibles of twelve New Zealand white rabbits. The biological effects were evaluated by Micro-computed tomography (Micro-CT) analysis and histological evaluation after 1, 2, and 4 weeks of healing. Results: Phytic acid/calcium hydroxide composite coating with superior hydrophilicity were successfully prepared on titanium implants. The surface characteristics showed Ti-SLA-2/10 implants with multiple pits and craters can release calcium ions continuously. In vivo, the volume of new bone around the Ti-SLA-2/10 implants was significantly higher than that of the Ti-SLA implants, but more fibrous tissue was observed surround the Ti-SLA implants after 1 week of healing. The Ti-SLA-2/10 implants showed higher bone volume fraction (bone volume/total volume, BV/TV, %) than that of the Ti-SLA implants at each time points (p

Bio-Implant Interface

Author : J.E. Ellingsen
Publisher : CRC Press
ISBN 13 : 1135508216
Total Pages : 593 pages
Book Rating : 4.1/5 (355 download)

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Book Synopsis Bio-Implant Interface by : J.E. Ellingsen

Download or read book Bio-Implant Interface written by J.E. Ellingsen and published by CRC Press. This book was released on 2003-04-29 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: Achieving good clinical outcomes with implanted biomaterials depends upon achieving optimal function, both mechanical and biological, which in turn depends upon integrating advances realized in biological science, material science, and tissue engineering. As these advances push back the frontiers of biomaterial medicine , the control and patterning

Advanced Ceramics for Dentistry

Author : James Zhijian Shen
Publisher : Elsevier Inc. Chapters
ISBN 13 : 0128060166
Total Pages : 32 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Advanced Ceramics for Dentistry by : James Zhijian Shen

Download or read book Advanced Ceramics for Dentistry written by James Zhijian Shen and published by Elsevier Inc. Chapters. This book was released on 2013-09-05 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioactive ceramics are used as bulk, porous bodies, or surface-active layers on dental implants and as morphogenetically active scaffolds inserted into the jawbone. While the former has been popularly applied as artificial dental roots for recovering the function of lost teeth, the latter are increasingly used for regenerating bone tissue. In both cases, the common fundamental basis is to understand how the new bone is formed on the surfaces of introduced foreign bodies, integrated together with the autologous bone through complex biological processes and cell-materials interactions. Efforts are thus made in this chapter to elucidate the biological origins of those phenomenological terms that have often eluded satisfactory scientific definition on this particular topic of practice-motivated science. Bone-growth mechanisms are discussed together with possible characterization and quantification methods. The role of surface morphology and multi-scale structures in promoting bone growth is emphasized. Based on the state-of-the-art understanding all the way down to molecular, cellular, and genetic levels, bioactive ceramics are categorized and presented in relation to their potential applications in dentistry. The design concept of implants for enhancing early healing and for enabling immediate loading is also discussed.

Biomaterials and Engineering for Implantology

Author : Yoshiki Oshida
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110740230
Total Pages : 562 pages
Book Rating : 4.1/5 (17 download)

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Book Synopsis Biomaterials and Engineering for Implantology by : Yoshiki Oshida

Download or read book Biomaterials and Engineering for Implantology written by Yoshiki Oshida and published by Walter de Gruyter GmbH & Co KG. This book was released on 2022-02-07 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomaterials are composed of metallic materials, ceramics, polymers, composites and hybrid materials. Biomaterials used in human beings require safety regulations, toxicity, allergic reaction, etc. When used as implantable materials their biological compatibility, biomechanical compatibility, and morphological compatibility must be acessed. This book explores the design and requirements of biomaterials for the use in implantology.

Titanium Alloys

Author : Jan Sieniawski
Publisher : BoD – Books on Demand
ISBN 13 : 9535111108
Total Pages : 160 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Titanium Alloys by : Jan Sieniawski

Download or read book Titanium Alloys written by Jan Sieniawski and published by BoD – Books on Demand. This book was released on 2013-05-15 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book contains six chapters and covers topics dealing with biomedical applications of titanium alloys, surface treatment, relationships between microstructure and mechanical and technological properties, and the effect of radiation on the structure of the titanium alloys.

The Application of the Ultrafine Technology in Improving the Biocompatibility and Osteo-inductivity of Dental Implants

Author : Nicholas Y. Hou
Publisher :
ISBN 13 :
Total Pages : 328 pages
Book Rating : 4.:/5 (16 download)

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Book Synopsis The Application of the Ultrafine Technology in Improving the Biocompatibility and Osteo-inductivity of Dental Implants by : Nicholas Y. Hou

Download or read book The Application of the Ultrafine Technology in Improving the Biocompatibility and Osteo-inductivity of Dental Implants written by Nicholas Y. Hou and published by . This book was released on 2015 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dental implants are very effective medical devices. However, although stable, the conventional titanium implants are not very bioactive which in some instances could reduce their efficacy. This thesis described the research progress of using polymeric ultrafine-particles with bioactive additives to enrich the surface of titanium substrate, thereby increasing the biocompatibility and osteo-inductivity of the biomaterial. During this doctoral project, three different types of polymers were examined, initially the conventional polyester, and later the novel epoxy as well as the epoxy/polyester hybrid polymers. Physical characterizations confirmed that all of the coating powders were ultrafine particles, and homogeneous surfaces were constructed from these particles with the correct incorporation of the functional and flow additives. The biocompatibility of the enriched surfaces were confirmed after examining their water contact angles, cell attachment/proliferation abilities, and their mitochondrial activities. After proliferation and differentiation, the osteo-inductivity of the surfaces were studied by labelling the mineral deposits that were formed on the surfaces. In addition to the biological performance, the adhesive strength of the enrichment layer was also assessed. After comparing between calcium oxide and calcium phosphate as the bioactive additive, and a series of different epoxy and polyester based polymers in the presence/absence of micron-sized TiO2, the results showed that the calcium oxide and micron-sized TiO2 containing epoxy/polyester hybrid surface was the best candidate for future clinical in vivo studies. From this study, a better understanding in the factors that affect the biocompatibility and osteo-inductivity of titanium substrate were obtained in order to create more effective biomaterials.

Titanium in Medical and Dental Applications

Author : Francis Froes
Publisher : Woodhead Publishing
ISBN 13 : 0128124571
Total Pages : 656 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Titanium in Medical and Dental Applications by : Francis Froes

Download or read book Titanium in Medical and Dental Applications written by Francis Froes and published by Woodhead Publishing. This book was released on 2018-05-09 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: Titanium in Medical and Dental Applications is an essential reference book for those involved in biomedical materials and advanced metals. Written by well-known experts in the field, it covers a broad array of titanium uses, including implants, instruments, devices, the manufacturing processes used to create them, their properties, corrosion resistance and various fabrication approaches. Biomedical titanium materials are a critically important part of biomaterials, especially in cases where non-metallic biomedical materials are not suited to applications, such as the case of load-bearing implants. The book also covers the use of titanium for implants in the medical and dental fields and reviews the use of titanium for medical instruments and devices. Provides an understanding of the essential and broad applications of Titanium in both the medical and dental industries Discusses the pathways to manufacturing titanium into critical biomedical and dental devices Includes insights into further applications within the industry

Racing for the Surface

Author : Bingyun Li
Publisher : Springer Nature
ISBN 13 : 3030344754
Total Pages : 648 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Racing for the Surface by : Bingyun Li

Download or read book Racing for the Surface written by Bingyun Li and published by Springer Nature. This book was released on 2020-03-02 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the latest research in biofilm, infection, and antimicrobial strategies in reducing and treating musculoskeletal, skin, transfusion, implant-related infections, etc. Topics covered include biofilms, small colony variants, antimicrobial biomaterials (antibiotics, antimicrobial peptides, hydrogels, bioinspired interfaces, immunotherapeutic approaches, and more), antimicrobial coatings, engineering and 3D printing, antimicrobial delivery vehicles, and perspectives on clinical impacts. Antibiotic resistance, which shifts the race toward bacteria, and strategies to reduce antibiotic resistance, are also briefly touched on. Combined with its companion volume, Racing for the Surface: Pathogenesis of Implant Infection and Advanced Antimicrobial Strategies, this book bridges the gaps between infection and tissue engineering, and is an ideal book for academic researchers, clinicians, industrial engineers and scientists, governmental representatives in national laboratories, and advanced undergraduate students and post-doctoral fellows who are interested in infection, microbiology, and biomaterials and devices.