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Neurohypophysial Hormones And Similar Polypeptides
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Book Synopsis Neurohypophysial Hormones and Similar Polypeptides. by : Botond Berde
Download or read book Neurohypophysial Hormones and Similar Polypeptides. written by Botond Berde and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 987 pages. Available in PDF, EPUB and Kindle. Book excerpt: production of this volume of the Handbook. If this joint enterprise has succeeded it is thanks to their competence, knowledge and application, for the editor's role is merely that of a coordinator. My thanks are also due to Springer-Verlag, the publishers, who gave me every possible assistance in seeing this volume to completion. Dr. D. Maroske was kind enough to prepare the Subject Index. And lastly I should like to voice my indebtedness to the Management of Sandoz Ltd., Basle, which allowed me to devote a not inconsiderable part of my time to the editing of this volume. I am also very grateful to a number of members of the staff of Sandoz Ltd.: to Mr. J.E. Smith, B. Sc., F.1. L., who translated some chapters and revised the language of others and to Miss Hannelore Straube and Miss Sonja Ebner for their valuable secreterial help.
Book Synopsis Mechanisms of Hormone Action by : P Karlson
Download or read book Mechanisms of Hormone Action written by P Karlson and published by Elsevier. This book was released on 2013-10-22 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanisms of Hormone Action: A NATO Advanced Study Institute focuses on the action mechanisms of hormones, including regulation of proteins, hormone actions, and biosynthesis. The selection first offers information on hormone action at the cell membrane and a new approach to the structure of polypeptides and proteins in biological systems, such as the membranes of cells. Discussions focus on the cell membrane as a possible locus for the hormone receptor; gaps in understanding of the molecular organization of the cell membrane; and a possible model of hormone action at the membrane level. The text also ponders on insulin and regulation of protein biosynthesis, including insulin and protein biosynthesis, insulin and nucleic acid metabolism, and proposal as to the mode of action of insulin in stimulating protein synthesis. The publication elaborates on the action of a neurohypophysial hormone in an elasmobranch fish; the effect of ecdysone on gene activity patterns in giant chromosomes; and action of ecdysone on RNA and protein metabolism in the blowfly, Calliphora erythrocephala. Topics include nature of the enzyme induction, ecdysone and RNA metabolism, and nature of the epidermis nuclear RNA fractions isolated by the Georgiev method. The selection is a valuable reference for readers interested in the mechanisms of hormone action.
Book Synopsis Neurosciences - From Molecule to Behavior: a university textbook by : C. Giovanni Galizia
Download or read book Neurosciences - From Molecule to Behavior: a university textbook written by C. Giovanni Galizia and published by Springer Science & Business Media. This book was released on 2013-07-08 with total page 735 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurosciences – a comprehensive approach This textbook covers neuroscience from cellular and molecular mechanisms to behavior and cognitive processing. We also address evolution of the nervous system, computational neuroscience, the history of neuroscience as a discipline and neurophilosophy – to name but a few. The book provides the newest state-of-the-art knowledge about neuroscience from across the animal kingdom, with particular emphasis on model species commonly used in neuroscience labs across the world: mouse, zebra fish, fruit fly, honeybee, and nematode worm. We aim at university students of neuroscience, psychology, biological sciences, and medical sciences, but also computer scientists, philosophers, or anybody interested in understanding how brains work.
Download or read book Vasopeptides written by N. Back and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: The dynamic state of developments within the field of the vasoactive polypeptides is reflected in the continuous series of publications appearing on this topic Thus, the proposal to con o vene another symposium only two years after the 1969 Fiesole Symposium (Plenum Press, 1970) was received enthusiastically and with high expectation. Enthusiasm was based, undoubtedly, in part on meeting together once again in the very pleasant surroundings of Florence with most gracious and enchanting hosts. The 25th International Congress on Physiological Sciences held in Munich the following week also provided the impetus for the organization of this satellite symposium on vasopeptides. However, the accelerated pace of research in the "kinin" field was the major motivating force for the symposium. It was felt necessary to inform each other of the many advances that were taking place in the varied aspects of this specialized but impor tant field o The role of kinins in both physicologic and pathologic processes still remains to be elucidated definitively. Thus, these proceedings contain new and unpublished informa tion on the chemistry, biochemistry, physicology, pharmacology, as well as pathophysiology of vasopeptides. Recent data on &tructure activity relationships of kinin analogues are complemented by a description of radioimmunoassay techniques for kinins, and studies on the site of synthesis of substrates for kinin-forming enzymes.
Book Synopsis Assay of Protein and Polypeptide Hormones by : H. Van Cauwenberge
Download or read book Assay of Protein and Polypeptide Hormones written by H. Van Cauwenberge and published by Elsevier. This book was released on 2014-05-17 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Series of Monographs in Pure and Applied Biology, Modern Trends in Physiological Sciences, Volume 33: Assay of Protein and Polypeptide Hormones focuses on the assays of protein and polypeptide hormones. The selection first discusses the general principles of protein and polypeptide hormone assays, including conditions and basic factors for bioassays and status of biological assays. The book looks at the assays of hypophyseal hormones, such as growth hormones, adrenocorticotropin (ACTH), thyrotropin, gonadotropins, prolactin, vasopressin, and oxytocin. Concerns include radioimmunoassay, standards of thyrotropin, immunoassay of hypophyseal gonadotropins, and bioassay of prolactin. The book evaluates the assays of pancreatic hormones, such as insulin and glucagon. Chemical structure and properties of insulin and radioimmunoassay of glucagon are explained. The text also focuses on the assays of erythropoietin, renin, human chorionic gonadotropin, and human placental lactogen (HPL). Concerns include augmentation of red cell volume; biological application of renin assays; and similarities and differences between hypophyseal somatotropin and HPL. The selection is a valuable source of data for readers interested in the assays of protein and polypeptide hormones.
Download or read book The Pituitary written by Shlomo Melmed and published by Academic Press. This book was released on 2010-12-09 with total page 745 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pituitary, albeit a small gland, is known as the "master gland" of the endocrine system and contributes to a wide spectrum of disorders, diseases, and syndromes. Since the publication of the second edition of The Pituitary, in 2002, there have been major advances in the molecular biology research of pituitary hormone production and action and there is now a better understanding of the pathogenesis of pituitary tumors and clinical syndromes resulting in perturbation of pituitary function. There have also been major advances in the clinical management of pituitary disorders. Medical researchers and practitioners now better understand the morbidity and mortality associated with pituitary hormone hyposecretion and hypersecretion. Newly developed drugs, and improved methods of delivering established drugs, are allowing better medical management of acromegaly and prolactinoma. These developments have improved the worldwide consensus around the definition of a "cure" for pituitary disease, especially hormone hypersecretion, and hence will improve the success or lack of success of various forms of therapy. It is therefore time for a new edition of The Pituitary. The third edition will continue to be divided into sections that summarize normal hypothalamic-pituitary development and function, hypothalamic-pituitary failure, and pituitary tumors; additional sections will describe pituitary disease in systemic disorders and diagnostic procedures, including imaging, assessment of the eyes, and biochemical testing. The first chapter will be completely new – placing a much greater emphasis on physiology and pathogenesis. Two new chapters will be added on the Radiation and Non-surgical Management of the Pituitary and Other Pituitary Lesions. Other chapters will be completely updated and many new author teams will be invited. The second edition published in 2002 and there have been incredible changes in both the research and clinical aspects of the pituitary over the past 8 years – from new advances in growth hormones to pituitary tumor therapy. - Presents a comprehensive, translational source of information about the pituitary in one reference work - Pituitary experts (from all areas of research and practice) take readers from the bench research (cellular and molecular mechanism), through genomic and proteomic analysis, all the way to clinical analysis (histopathology and imaging) and new therapeutic approaches - Clear presentation by endocrine researchers of the cellular and molecular mechanisms underlying pituitary hormones and growth factors as well as new techniques used in detecting lesions (within the organ) and other systemic disorders - Clear presentation by endocrinologists and neuroendocrine surgeons of how imaging, assessment of the eyes, and biochemical testing can lead to new therapeutic approaches
Download or read book The Pineal Gland written by I. Nir and published by . This book was released on 2015-01-07 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Pharmacology of Hormonal Polypeptides and Proteins by : Nathan Back
Download or read book Pharmacology of Hormonal Polypeptides and Proteins written by Nathan Back and published by Springer. This book was released on 2013-12-11 with total page 671 pages. Available in PDF, EPUB and Kindle. Book excerpt: It can be concluded (under the specific experimental procedures em ployed) that:- 1) HCG labelled with 1 - 2 atoms of radioactive iodine did not differ sig nificantly from the unlabelled hormone; 2) The ovary alone exhibited a capacity to affix specifically HCG; 3) The amount of radioactive material in the ovary was directly proport ional to the quantity of labelled HCG injected; 4) When the HCG present in the circulation is bound to an antiserum to HCG, the antigen-antibody complex is not concentrated by the ovary; 5) Circulating labelled HCG decreased to 50% within 30 minutes following a single intravenous injection; 6) There are four different phases of ovarian uptake of HCG, namely: the first phase, when there is only an inflow from the circulation and stor age mainly in the follicular envelopes; the second phase, when there is a greater inflow than outflow; the third phase, when the inflow is equal to the outflow; and the fourth period, when the outflow is bigger than the in flow. REFERENCES 1. Lunenfeld, B. and Eshkol, A. Vitamins and Hormones (1967) 25:165 2. Eshkol, A. In: Recent Research on Gonadotropbio Hormones, eds. E. T. Bell andJ. A. Loraine, Edinburgh, Livingstone (1967), p. 202. 3. Eshkol, A. and Lunenfeld, B. Proc. Tel-Hashomer Hosp. (1967) 6:4. ACKNOWLEOOMEN'IS This work was supported in part by a grant from the Population Council, N. Y. , U. S. A. andbyGrantNo.
Book Synopsis Schizophrenia and Psychotic Spectrum Disorders by : S. Charles Schulz
Download or read book Schizophrenia and Psychotic Spectrum Disorders written by S. Charles Schulz and published by Oxford University Press. This book was released on 2016-04-01 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: Schizophrenia and Psychotic Spectrum Disorders aims to engage young caregivers in psychiatry, psychology, nursing and social work so that they will be able to become well informed about this significant--and at times confusing--illness. Because schizophrenia is considered to be one of the most complicated and severe psychiatric disorders, this book has the goal of summarizing key issues of the illness, such as its presentation, frequency and age of onset, and diagnostic characteristics. It also contains informative chapters about the pathophysiology of schizophrenia, ranging from brain development issues, genetics, and likely abnormalities in neurotransmitters. This book will give young professionals and those joining the field an excellent and accessible background to treatment. In this area, Schizophrenia and Psychotic Spectrum Disorders provides a comprehensive approach to diagnosis, treatment initiation, strategies for non-response, approaches of therapy, and importantly, ways to provide family therapy and support.
Book Synopsis The World of Peptides by : Theodor Wieland
Download or read book The World of Peptides written by Theodor Wieland and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Almost two centuries ago proteins were recognized as the primary materials (proteios = primary) oflife, but the significance and wide role of peptides (from pepsis = digestion) in practically all life pro cesses has only become apparent in the last few decades. Biologi cally active peptides are now being discovered at rapid intervals in the brain and in other organs including the heart, in the skin of amphibians and many other tissues. Peptides and peptide-like compounds are found among toxins and antibiotics. It is unlikely that this process, an almost explosive broadening of the field, will come to a sudden halt. By now it is obvious that Nature has used the combination of a small to moderate number of amino acids to generate a great variety of agonists with specific and often highly sophisticated functions. Thus, peptide chemistry must be regarded as a discipline in its own right, a major branch of biochemistry, fairly separate from the chemistry of proteins. Because of the important role played by synthesis both in the study and in the practical preparation of peptides, their area can be considered as belonging to bio-organic chemistry as well. The already overwhelming and still increasing body of know ledge renders an account of the history of peptide chemistry more and more difficult. It appears therefore timely to look back, to take stock and to recall the important stages in the development of a new discipline.
Book Synopsis Gigantism and Acromegaly by : Constantine A. Stratakis
Download or read book Gigantism and Acromegaly written by Constantine A. Stratakis and published by Academic Press. This book was released on 2021-06-01 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gigantism and Acromegaly brings together pituitary experts, taking readers from bench research, to genetic analysis, clinical analysis, and new therapeutic approaches. This book serves as a reference for growth hormone over-secretion and its diagnosis and treatment for endocrinologists, pediatricians, internists, and neurosurgeons, and for geneticists. Pharmaceutical companies may use it as a reference for drug development and research. Students, residents and fellows in medicine and endocrinology and genetics will also find it valuable as it provides a single up-to-date review of the molecular biology of gigantism and acromegaly as well as recommended approaches to evaluation and management. Acromegaly is a rare pituitary disorder that slowly changes its adult victim's appearance over time: larger hands and feet, bigger jaw, forehead, nose, and lips. Generally, a benign pituitary tumor is the cause and symptoms of acromegaly can vary from patient to patient, making a diagnosis difficult and prolonging suffering for years. Early detection is key in the management of acromegaly as the pathologic effects of increased growth hormone (GH) production are progressive and can be life-threatening as the result of associated cardiovascular, cerebrovascular, and respiratory disorders and malignancies. - Accessible, up-to-date overview of the characteristics, state-of-the-art diagnostic procedures, and management of acromegaly and gigantism - Provides a unique compendium of endocrinology, genetics, clinical diagnosis and therapeutics - Contains contributions from internationally known experts who have treated patients with acromegaly and gigantism
Book Synopsis Peptides in Neurobiology by : Harold Gainer
Download or read book Peptides in Neurobiology written by Harold Gainer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Sound Communication in Fishes by : Friedrich Ladich
Download or read book Sound Communication in Fishes written by Friedrich Ladich and published by Springer. This book was released on 2015-03-26 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume examines fish sounds that have a proven signal function, as well as sounds assumed to have evolved for communication purposes. It provides an overview of the mechanisms, evolution and neurobiology behind sound production in fishes, and discusses the role of fish sounds in behavior with a special focus on choice of mate, sex-specific and age-specific signaling. Furthermore, it highlights the ontogenetic development of sound communication and ecoacoustical conditions in fish habitats and the influence of hormones on vocal production and sound detection. Sound Communication in Fishes offers a must-have compendium for lecturers, researchers and students working in the fields of animal communication, fish biology, neurobiology and animal behavior.
Book Synopsis Neuroendocrine Control by : Kinji Yagi
Download or read book Neuroendocrine Control written by Kinji Yagi and published by John Wiley & Sons. This book was released on 1973 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Peptides written by Bernd Gutte and published by Elsevier. This book was released on 1995-10-24 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, research has shown the importance of peptides in neuroscience, immunology, and cell biology. Active research programs worldwide are now engaged in developing peptide-based drugs and vaccines using modification of natural peptides and proteins, design of artificial peptides and peptide mimetics, and screening of peptide and phage libraries. In this comprehensive book, the authors discuss peptide synthesis and application within the context of their increasing importance to the pharmaceutical industry. Peptides: Synthesis, Structures, and Applications explores the broad growth of information in modern peptide synthetic methods and the structure-activity relationships of synthetic polypeptides. - The history of peptide chemistry - Amide formation, deprotection, and disulfide formation in peptide synthesis - Solid-phase peptide synthesis - a-helix formation by peptides in water - Stability and dynamics of peptide conformation - An overview of structure-function studies of peptide hormones - Neuropeptides:peptide and nonpeptide analogs - Reversible inhibitors of serine proteinases - Design of polypeptides - Current capabilities and future possibilities of soluble chemical combinatorial libraries - Epitope mapping with peptides - Synthesis and applications of branched peptides in immunological methods and vaccines
Book Synopsis The Chemistry of Polypeptides by : P. Katsoyannis
Download or read book The Chemistry of Polypeptides written by P. Katsoyannis and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leonidas Zervas, Emeritus Professor of organic chemistry at the University of Athens, and past president of the National Academy of Greece, cele brated his seventieth birthday this past year. For almost fifty years Zervas devoted his scientific skills and perception to the advancement of chemistry, particularly in the field of peptides and proteins. Indeed, his efforts, along with those of his teacher, co-worker, and friend, Max Bergmann, laid the foundations for a new era in the chemistry of peptides and proteins. Many of his colleagues and former students felt that it would be most at this time to honor him with a commemorative volume. They appropriate have contributed to this volume chapters describing some of their work and reviewing the advancements in particular areas of polypeptide chemistry. They dedicate this volume to Leonidas Zervas as an expression of their esteem and appreciation for the role he has played for the past half-century in the field of peptides and proteins.
Book Synopsis Neurohormones and Neurohumors by : J. Ariëns Kappers
Download or read book Neurohormones and Neurohumors written by J. Ariëns Kappers and published by Springer. This book was released on 2013-11-21 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Having accepted the task to organize, in Amsterdam, an international Congress in behalf of the International Sodety for Neurovegetati'V'e Research such as is held every second year, it occurred to me that it might be worth while to change its usual pattern somewhat. Instead of giving merely the opportunity for l'eading a nurnber of rather short free papers, more or less grouped in many categories, we decided to start with a symposium on a special topic 'to be dealt with from several aspects by a numbe·r of invited speakers, the last day of the congress being only available for short free communications. The central topic for the symposium finally chosen was "Neurohormones and N eurohumors" as this subject is of interest :to many morphologists, physiologists, pharmacologists, neuro-endocrinologists, biochemists and clini cians, and belongs to a rapidly expanding Held of research. Moreover, it appeared to us that there is some confusion about the defini tion of these terms which are not seLdom used indifferently. I hoped that such a symposium would contribute 1to a clearer apprehension of the terms based on morphological, physiological and biochemical criteria as well as to a clearer understanding of some problems involved which will have to be subjects of future investigations.