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Neurochemistry Of Abused Drugs
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Book Synopsis Neurochemistry of Abused Drugs by : MD, FFFLM, Steven B. Karch
Download or read book Neurochemistry of Abused Drugs written by MD, FFFLM, Steven B. Karch and published by CRC Press. This book was released on 2007-10-09 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extracted from the Drug Abuse Handbook, 2nd edition, to give you just the information you need at an affordable price. Beginning with a detailed look at individual drugs and their effects on the brain, Neurochemistry of Abused Drugs considers the changes in neurotransmitter levels and discusses the relationship of these
Book Synopsis The Neurochemistry of Drugs of Abuse by : Syed F. Ali
Download or read book The Neurochemistry of Drugs of Abuse written by Syed F. Ali and published by . This book was released on 1998 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contains 34 papers from a 1997 meeting of the International Society for Neurochemistry and the American Society for Neurochemistry, convened in Hamilton, Bermuda, clarifying cellular and molecular mechanisms of abused drugs and of pharmacotherapies for drug addition. Papers are organized in sections on gene expression and molecular mechanisms of drug addiction, drugs of abuse and medication development (cocaine and ibogaine), the role of free radicals in drug- induced neurotoxicity, specific neuronal markers in substituted amphetamine-induced toxicity, and prenatal exposure and outcome. Annotation copyrighted by Book News, Inc., Portland, OR
Download or read book Drugs, Brains, and Behavior written by and published by . This book was released on 2007 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Drugs, Brains, and Behavior: The Science of Addiction by :
Download or read book Drugs, Brains, and Behavior: The Science of Addiction written by and published by . This book was released on with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Behavioral Neuroscience of Drug Addiction by : David W. Self
Download or read book Behavioral Neuroscience of Drug Addiction written by David W. Self and published by Springer Science & Business Media. This book was released on 2009-12-18 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug addiction is a chronically relapsing mental illness involving severe motivational disturbances and loss of behavioral control leading to personal dev- tation. The disorder af?icts millions of people, often co-occurring with other mental illnesses with enormous social and economic costs to society. Several decades of research have established that drugs of abuse hijack the brain’s natural reward substrates, and that chronic drug use causes aberrant alterations in these rewa- processing systems. Such aberrations may be demonstrated at the cellular, neu- transmitter, and regional levels of information processing using either animal models or neuroimaging in humans following chronic drug exposure. Behaviorally, these neural aberrations manifest as exaggerated, altered or dysfunctional expr- sion of learned behavioral responses related to the pursuit of drug rewards, or to environmental factors that precipitate craving and relapse during periods of drug withdrawal. Current research efforts are aimed at understanding the associative and causal relationships between these neurobiological and behavioral events, such that treatment options will ultimately employ therapeutic amelioration of neural de?cits and restoration of normal brain processing to promote efforts to abstain from further drug use. The Behavioral Neuroscience of Drug Addiction, part of the Springer series on Current Topics in Behavioral Neurosciences, contains scholarly reviews by noted experts on multiple topics from both basic and clinical neuroscience ?elds.
Book Synopsis Alcohol and Opiates by : Kenneth Blum
Download or read book Alcohol and Opiates written by Kenneth Blum and published by Elsevier. This book was released on 2012-12-02 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol and Opiates: Neurochemical and Behavioral Mechanisms contains the proceedings of the 1976 conference, ""The Neurochemical and Behavioral Mechanisms of Alcohol and Opiate Dependence"", held in New York. The papers focus on the commonalities and distinctions of alcohol and opiates in terms of neurochemical and behavioral mechanisms. It also highlights key research findings on alcohol and drug dependence as well as advances in the understanding of opiate neurochemistry and the nature of alcoholism. Organized into two sections comprised of 22 chapters, this compilation begins with an overview of the various techniques used to produce and to measure alcohol dependence using animal models. It then discusses the neurochemical components of ethanol dependence, the pharmacogenetics of alcoholism, and the effects of alcohol on behavioral performance. The remaining chapters examine the pharmacology of isoquinoline alkaloids and ethanol interactions, the neurochemical aspects of opiate dependence, the pharmocological heterogeneity of narcotic receptors, and the pharmacology of endogenous opiate-like peptides. The book also introduces the reinforcement of behavior by morphine injections and the metabolic stereospecificity of opiate agonist and antagonist drugs. It concludes with an assessment of future research directions concerning opioid peptides (endorphins). This book is a valuable source of information for those seeking to build clinical programs designed to alleviate the sociological and medical ills associated with alcohol and opiate abuse and drug dependency.
Book Synopsis Molecular and Cellular Aspects of the Drug Addictions by : Avram Goldstein
Download or read book Molecular and Cellular Aspects of the Drug Addictions written by Avram Goldstein and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1970 I gave up the chairmanship of the Department of Pharmacology at Stanford University Schoel of Medicine to devote full time to basic and clinical research on problems of drug addiction. In 1971 I developed the method of radioligand binding that led to the important characterization of opioid receptors in several laboratories. The extraordinary specificity of these receptors for morphine and related opiates suggested the likelihood that there were naturally occurring morphine-like molecules in the brain and other tissues. The systematic search for these molecules culminated in 1979 in the discovery, by my group, ofthe dynorphin peptides-one of the three families of opioid peptides, the first of which (the enkephalin family) had been discovered in Aberdeen, Scotland, in 1975. I also became involved in clinical research on the pharmacologic treatment of heroin addicts, for which I established the first large methadone mainte nance treatment program in California. My basic and clinical research experience convinced me that an institution encompassing laboratory research, studies on normal human volunteers, and treatment research, under a single roof, could expedite progress in understanding the drug addictions. That concept was transformed into reality by the founding, in 1974, of the Addiction Research Foundation of Palo Alto, California. The funds for construction of a laboratory were provided by a generous grant from the Drug Abuse Council (a consortium of several foundations), the president of which was Thomas L. Bryant.
Book Synopsis Methods in Drug Abuse Research by : Barry D. Waterhouse
Download or read book Methods in Drug Abuse Research written by Barry D. Waterhouse and published by CRC Press. This book was released on 2002-11-25 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of drug addiction and substance abuse, which was initially confined to behavioral studies, has broadened dramatically. It now includes a vast array of cellular and molecular approaches as well as sophisticated electrophysiological and neurochemical methodologies that bridge the gap between cellular/molecular events and behavior. In many cases, these techniques are used to clarify and characterize specific dimensions of the addictive process or actions of potential abuse. Methods of Drug Abuse Research: Cellular and Circuit Level Analyses assembles this information in one volume. It bridges the gap between cellular and molecular studies of drug actions and behavioral approaches to questions in drug abuse research. The book presents state-of-the-art technical information and critical reviews of the experimental strategies used to dissect the problem of compulsive drug use and addiction at the systems or whole brain level. Chapters provide examples of the use of neurochemical and delectrophysiological the techniques in drug studies, as well as insight into the pros and cons of these various experimental strategies. Focusing on neurochemical and neurophysiological techniques that assess drug actions on neural circuits and neural networks in intact animals, this state-of-the-art reference provides detailed descriptions of procedures as well as methods and equipment used in experiments that often employ multiple technical approaches. Methods of Drug Abuse Research brings together pertinent issues in drug abuse research and systems level investigative techniques, thus allowing you to effectively grasp the critical conceptual and technical issues associated with modern drug abuse studies.
Author :Reinhard Grzanna Publisher :Department of Health and Human Services Public Health Servic ISBN 13 : Total Pages :232 pages Book Rating :4.:/5 (319 download)
Book Synopsis Activation of Immediate Early Genes by Drugs of Abuse by : Reinhard Grzanna
Download or read book Activation of Immediate Early Genes by Drugs of Abuse written by Reinhard Grzanna and published by Department of Health and Human Services Public Health Servic. This book was released on 1993 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Chemical Brain by : Sidney Cohen
Download or read book The Chemical Brain written by Sidney Cohen and published by Careinstitute. This book was released on 1988 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Pharmacology of Alcohol and Drugs of Abuse and Addiction by : Norman S. Miller
Download or read book The Pharmacology of Alcohol and Drugs of Abuse and Addiction written by Norman S. Miller and published by . This book was released on 1991 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: This book is intended for use by clinicians, researchers, residents, and students. The text includes sections on the pharmacology of abuse and addiction (neurochemistry, behavioral aspects, genetics, medical and psychiatric consequences, etc.), drug-drug interactions, abstinence and prevention.
Book Synopsis Drug Abuse Handbook, Second Edition by : Steven B. Karch, MD, FFFLM
Download or read book Drug Abuse Handbook, Second Edition written by Steven B. Karch, MD, FFFLM and published by CRC Press. This book was released on 2006-12-21 with total page 1288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following the well-received first edition, the Drug Abuse Handbook, Second Edition is a thorough compendium of the knowledge of the pharmacological, medical, and legal aspects of drugs. The book examines criminalistics, pathology, pharmacokinetics, neurochemistry, treatment, as well as drugs and drug testing in the workplace and in sports, and the ethical, legal, and practical issues involved. Dr. Karch gathers contributions from 80 leading experts in their respective fields to update and revise this second edition with more than 40 percent new material. New topics include genetic testing in drug death investigation, the neurochemistry of nicotine and designer amphetamines, genetic doping in sports, and the implications of the Daubert ruling on the admissibility of scientific evidence in federal court. Packed with the latest information in an easily accessible format, the book includes tables of all Scheduled Drugs, methods of Drug Quantitative Analysis, and a glossary of forensic toxicology terms. Vivid pictures and diagrams illustrate the pathological effects of drugs and the chemical make-up and breakdown of abused drugs. It includes more than 6000 references to the best sources in medicine, pharmacology, and the law. This book addresses specific problems in drug testing, drug-related medical emergencies, and the physical, neurochemical, and sociological phenomenon of addiction. With unparalleled detail and the highest level of authoritative information, The Drug Abuse Handbook, Second Edition is the definitive resource for drug related issues.
Book Synopsis Drugs of Abuse and Neurobiology by : Ronald Ross Watson
Download or read book Drugs of Abuse and Neurobiology written by Ronald Ross Watson and published by CRC PressI Llc. This book was released on 1992 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drugs of Abuse and Neurobiology is the first volume in a series dealing with the effects of drugs of abuse on various systems. The neurobiology and neurochemistry of such high-profile drugs as benzodiazepine, nicotine, PCP, and amphetamines are examined, and aspects such as drug-induced euphoria, sensorimotor integration, pharmacodynamics of addiction, and other neurologic sequalae are considered. Collectively, the volume offers a definitive and authoritative review of current research in the field. Drugs of Abuse and Neurobiology will be a useful addition to the bookshelves of researchers, clinicians, and students studying the complex changes caused by the direct and indirect effect of single drugs at the cellular level.
Download or read book Drug Addiction written by Syed F. Ali and published by Wiley-Blackwell. This book was released on 2008-11-03 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume brings together basic and clinical science to provide in-depth understanding and current knowledge concerning new conceptual insights into the CNS acting drugs and drugs of abuse and treatment of drug addiction. Methamphetamine, MDMA, PMA and different solvents are the most widely abused drugs in the Europe, United States, Central America, South America and Asian Countries and their use has dramatically increased over the last two decades. These drugs of abuse are known to cause neurotoxicity in several species including not only rodents, dogs and nonhuman primates, but also humans. However, precise neurochemical mechanisms underlying this drug-induced neurotoxicity remain unclear. This volume addresses the following: 1) Role of Genomics, Proteomics and Metabonomics in Drug-induced Neurotoxicity 2) Drugs of Abuse and Medication Development 3) Molecular Biology and Free Radicals in Drugs of Abuse-induced neurotoxicity 4) Substituted Amphetamines-induced Neurochemical Changes and Relationship to Neurotoxicity 5) Drug of Abuse and Imaging Brain Structure and Function 6) GHB/Volatile Solvent/Inhalant Neurotoxicity NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member
Book Synopsis Neurochemistry of Drugs of Abuse by : Syed F. Ali
Download or read book Neurochemistry of Drugs of Abuse written by Syed F. Ali and published by New York Academy of Sciences. This book was released on 2000-06-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although a tremendous body of data has been gathered on the neurochemical changes engendered by exposure to drugs of abuse, the cellular mechanisms responsible for the changes remains unclear. In The Neurochemistry of Drugs of Abuse Syed F. Ali and his co-authors examine the cellular and molecular mechanisms of drugs of abuse (such as cocaine and substituted amphetamines) as well as drugs that have been proposed for the treatment of drug addiction (such as ibogaine, phenyltropane, and phentermine-fenfluramine). Among the contributors, FDA researchers present the clinical aspect in the development of medications designed to treat drug addiction. Other chapters are devoted to the underlying mechanisms of drug addiction, such as gene expression/molecular mechanisms, medication development, free-radical induced neurotoxicity, and specific neuronal markers. Bringing together both clinical and basic scientists in a multidisciplinary and multinational forum, The Neurochemistry of Drugs of Abuse presents a significant exchange of ideas in this expanding field of research.
Book Synopsis Behavioral Neuroscience of Drug Addiction by : David W. Self
Download or read book Behavioral Neuroscience of Drug Addiction written by David W. Self and published by Springer. This book was released on 2009-11-19 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug addiction is a chronically relapsing mental illness involving severe motivational disturbances and loss of behavioral control leading to personal dev- tation. The disorder af?icts millions of people, often co-occurring with other mental illnesses with enormous social and economic costs to society. Several decades of research have established that drugs of abuse hijack the brain’s natural reward substrates, and that chronic drug use causes aberrant alterations in these rewa- processing systems. Such aberrations may be demonstrated at the cellular, neu- transmitter, and regional levels of information processing using either animal models or neuroimaging in humans following chronic drug exposure. Behaviorally, these neural aberrations manifest as exaggerated, altered or dysfunctional expr- sion of learned behavioral responses related to the pursuit of drug rewards, or to environmental factors that precipitate craving and relapse during periods of drug withdrawal. Current research efforts are aimed at understanding the associative and causal relationships between these neurobiological and behavioral events, such that treatment options will ultimately employ therapeutic amelioration of neural de?cits and restoration of normal brain processing to promote efforts to abstain from further drug use. The Behavioral Neuroscience of Drug Addiction, part of the Springer series on Current Topics in Behavioral Neurosciences, contains scholarly reviews by noted experts on multiple topics from both basic and clinical neuroscience ?elds.
Author :Friends of Psychiatric Research, inc Publisher :Johns Hopkins University Press ISBN 13 : Total Pages :426 pages Book Rating :4.4/5 (91 download)
Book Synopsis Drugs and the Brain by : Friends of Psychiatric Research, inc
Download or read book Drugs and the Brain written by Friends of Psychiatric Research, inc and published by Johns Hopkins University Press. This book was released on 1969 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt:
