Neurobiology Of Epilepsy And Aging

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Neurobiology of Epilepsy and Aging

Author : R. Eugene Ramsay
Publisher : Elsevier
ISBN 13 : 0080489257
Total Pages : 362 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Neurobiology of Epilepsy and Aging by : R. Eugene Ramsay

Download or read book Neurobiology of Epilepsy and Aging written by R. Eugene Ramsay and published by Elsevier. This book was released on 2007-04-16 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume in the International Review of Neurobiology series addresses the epidemiology, pathophysiology, and treatment of epilepsy in elderly patients. Demographically, the elderly comprise both the fastest-growing segment of the U.S. population and the adult age group with the highest incidence of epilepsy, yet there are relatively few publications devoted to this clinical subgroup. The intersection of these two complex processes—epilepsy and advancing age—will have an increasing impact on medical and community care. The etiology, prognosis, and differential diagnosis of epilepsy can all be affected by the normal aging process and by the frequent comorbidities encountered in an elderly population. Chapters in this book review the effects of aging on brain function and on drug metabolism and interactions, covering the gamut of research from animal models of aging and epilepsy to clinical trials and outcomes. Topics also include the dangers of misdiagnosing status epilepticus, the special issues encountered in recruiting and retaining elderly clinical trial participants, and the use of antiepileptic drugs in the elderly. In both the clinic and the research laboratory, a better understanding of how epilepsy may differ between younger and older patients will be valuable in determining the best possible care for geriatric patients with epilepsy.

The Neurobiology of Epilepsy and Aging

Author : R. Eugene Ramsay
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (122 download)

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Book Synopsis The Neurobiology of Epilepsy and Aging by : R. Eugene Ramsay

Download or read book The Neurobiology of Epilepsy and Aging written by R. Eugene Ramsay and published by . This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Epilepsy Across the Spectrum

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309259533
Total Pages : 568 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Epilepsy Across the Spectrum by : Institute of Medicine

Download or read book Epilepsy Across the Spectrum written by Institute of Medicine and published by National Academies Press. This book was released on 2012-07-29 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although epilepsy is one of the nation's most common neurological disorders, public understanding of it is limited. Many people do not know the causes of epilepsy or what they should do if they see someone having a seizure. Epilepsy is a complex spectrum of disorders that affects an estimated 2.2 million Americans in a variety of ways, and is characterized by unpredictable seizures that differ in type, cause, and severity. Yet living with epilepsy is about much more than just seizures; the disorder is often defined in practical terms, such as challenges in school, uncertainties about social situations and employment, limitations on driving, and questions about independent living. The Institute of Medicine was asked to examine the public health dimensions of the epilepsies, focusing on public health surveillance and data collection; population and public health research; health policy, health care, and human services; and education for people with the disorder and their families, health care providers, and the public. In Epilepsy Across the Spectrum, the IOM makes recommendations ranging from the expansion of collaborative epilepsy surveillance efforts, to the coordination of public awareness efforts, to the engagement of people with epilepsy and their families in education, dissemination, and advocacy for improved care and services. Taking action across multiple dimensions will improve the lives of people with epilepsy and their families. The realistic, feasible, and action-oriented recommendations in this report can help enable short- and long-term improvements for people with epilepsy. For all epilepsy organizations and advocates, local, state, and federal agencies, researchers, health care professionals, people with epilepsy, as well as the public, Epilepsy Across the Spectrum is an essential resource.

Encyclopedia of Basic Epilepsy Research

Author :
Publisher : Academic Press
ISBN 13 : 0123739616
Total Pages : 1853 pages
Book Rating : 4.1/5 (237 download)

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Book Synopsis Encyclopedia of Basic Epilepsy Research by :

Download or read book Encyclopedia of Basic Epilepsy Research written by and published by Academic Press. This book was released on 2009-05-27 with total page 1853 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a truly translational area of biomedical investigation, epilepsy research spans an extraordinary breadth of subjects and involves virtually every tool that modern neuroscience has at its disposal. The Encyclopedia of Basic Epilepsy Research provides an up to date, comprehensive reference for all epilepsy researchers. With an expert list of authors, the encyclopedia covers the full spectrum of research activities from genes and molecules to animal models and human patients. The encyclopedia's electronic format also provides unparalleled access to frequent updates and additions, while the limited edition print version provides another option for owning this content. The Encyclopedia of Basic Epilepsy Research is an essential resource for researchers of all levels and clinicians who study epilepsy. The only comprehensive reference for basic research and current activities in epilepsy Electronic format provides fast and easy access to updates and additions, with limited print version available as well Contains over 85 articles, all written by experts in epilepsy research

Seizures and Epilepsy in the Elderly

Author : A. J. Rowan
Publisher : Butterworth-Heinemann
ISBN 13 :
Total Pages : 368 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Seizures and Epilepsy in the Elderly by : A. J. Rowan

Download or read book Seizures and Epilepsy in the Elderly written by A. J. Rowan and published by Butterworth-Heinemann. This book was released on 1997 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epileptic seizures in the elderly population occur more frequently that previously thought. Recent epidemiologic data indicate that the incidence of seizures rises sharply after middle age. Seizures occur because of previous stroke or head trauma in addition to a variety of systemic derangements, drugs, drug withdrawal, or acute intracranial disease. The aging process creates particular problems in diagnosis, specific therapy, and long-term management. Prompt diagnosis and therapy are essential. This bookemphasizes the physiologic and pathologic changes associated with aging that have an impact on diagnosis and treatment. It will include epidemiology, clinical diagnosis, imaging and electrophysiologic studies, age-related physiologic changes, pharmacokinetics, drug interactions, current and new antiepileptic drugs, and management.

Oxford Textbook of Epilepsy and Epileptic Seizures

Author : Samden Lhatoo
Publisher : Oxford University Press
ISBN 13 : 0199659044
Total Pages : 395 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis Oxford Textbook of Epilepsy and Epileptic Seizures by : Samden Lhatoo

Download or read book Oxford Textbook of Epilepsy and Epileptic Seizures written by Samden Lhatoo and published by Oxford University Press. This book was released on 2013 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the Oxford Textbooks in Clinical Neurology (OTCN) series, this volume covers the scientific basis, clinical diagnosis, and treatment of epilepsy and epileptic seizures, and is complemented by an online edition.

Seizures and the Developing Brain

Author : Aristea S. Galanopoulou
Publisher : Biota Publishing
ISBN 13 : 1615043551
Total Pages : 72 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Seizures and the Developing Brain by : Aristea S. Galanopoulou

Download or read book Seizures and the Developing Brain written by Aristea S. Galanopoulou and published by Biota Publishing. This book was released on 2011-10-01 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: Seizures are more common early in life than in adulthood. Bidirectional interactions between seizures and normal developmental processes define their expression and outcomes. Several developmentally regulated factors control neuronal excitability. GABAA receptors hold a central role as they control neuronal activity in an age-specific manner. Early in development, GABAA receptors have depolarizing effects, which contribute to the increased susceptibility of immature neurons to seizures but they are also essential for normal brain development. During development, there is a gradual shift to the "adult-type" hyperpolarizing GABAA receptor signaling, creating more efficient inhibition. Seizures may disrupt GABAA receptor signaling by changing the expression of their subunits and by changing the direction of GABAA responses, which, in certain situations, may be detrimental for brain development. Furthermore, subcortical nuclei, such as the substantia nigra, control the expression and propagation of seizures in an age- and sex-dependent manner. These endogenous control centers and signaling pathways are further modified by independent genetic epigenetic, biologic, or other factors, which further increase the heterogeneity in presentation of seizures, their treatment, and their comorbidities. Elucidation of these complex interactions and identification of biomarkers guiding therapeutic interventions will be necessary to improve our ability to treat early-life epilepsies.

Jasper's Basic Mechanisms of the Epilepsies

Author : Jeffrey L. Noebels
Publisher : OUP USA
ISBN 13 : 0199746540
Total Pages : 1258 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Jasper's Basic Mechanisms of the Epilepsies by : Jeffrey L. Noebels

Download or read book Jasper's Basic Mechanisms of the Epilepsies written by Jeffrey L. Noebels and published by OUP USA. This book was released on 2012-06-29 with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.

Clinical Neurology of Aging

Author : Martin L. Albert
Publisher : Oxford University Press, USA
ISBN 13 : 9780195071672
Total Pages : 740 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Clinical Neurology of Aging by : Martin L. Albert

Download or read book Clinical Neurology of Aging written by Martin L. Albert and published by Oxford University Press, USA. This book was released on 1994 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thorough revision of a well-established text presents essential information on the neurobiology of aging. There are new chapters on competency and ethics, problems of daily living, psychopharmacology, and stability and falls. Written in a accessible style, this book will be invaluable to clinicians and neurologists who treat elderly patients.

Handbook on the Neuropsychology of Aging and Dementia

Author : Lisa D. Ravdin
Publisher : Springer Science & Business Media
ISBN 13 : 1461431069
Total Pages : 525 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Handbook on the Neuropsychology of Aging and Dementia by : Lisa D. Ravdin

Download or read book Handbook on the Neuropsychology of Aging and Dementia written by Lisa D. Ravdin and published by Springer Science & Business Media. This book was released on 2012-09-14 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the aging of the baby boomers and medical advances that promote longevity, older adults are rapidly becoming the fastest growing segment of the population. As the population ages, so does the incidence of age related disorders. Many predict that 15% - 20% of the baby-boomer generation will develop some form of cognitive decline over the course of their lifetime, with estimates escalating to up to 50% in those achieving advanced age. Although much attention has been directed at Alzheimer’s disease, the most common form of dementia, it is estimated that nearly one third of those cases of cognitive decline result from other neuropathological mechanisms. In fact, many patients diagnosed with Alzheimer’s disease likely have co-morbid disorders that can also influence cognition (i.e., vascular cognitive impairment), suggesting mixed dementias are grossly under diagnosed. The Clinical Handbook on the Neuropsychology of Aging and Dementia is a unique work that provides clinicians with expert guidance and a hands-on approach to neuropsychological practice with older adults. The book will be divided into two sections, the first addressing special considerations for the evaluation of older adults, and the second half focusing on common referral questions likely to be encountered when working with this age group. The authors of the chapters are experts and are recognized by their peers as opinion leaders in their chosen chapter topics. The field of neuropsychology has played a critical role in developing methods for early identification of late life cognitive disorders as well as the differential diagnosis of dementia. Neuropsychological assessment provides valuable clinical information regarding the nature and severity of cognitive symptoms associated with dementia. Each chapter will reinforce the notion that neuropsychological measures provide the clinician with sensitive tools to differentiate normal age-related cognitive decline from disease-associated impairment, aid in differential diagnosis of cognitive dysfunction in older adults, as well as identify cognitive deficits most likely to translate into functional impairments in everyday life.

Neurobiology of Epilepsy and Aging

Author : R. Eugene Ramsay
Publisher : Academic Press
ISBN 13 : 0123740185
Total Pages : 362 pages
Book Rating : 4.1/5 (237 download)

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Book Synopsis Neurobiology of Epilepsy and Aging by : R. Eugene Ramsay

Download or read book Neurobiology of Epilepsy and Aging written by R. Eugene Ramsay and published by Academic Press. This book was released on 2007-04-16 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses all aspects of epilepsy in aging patients.

Cognitive Plasticity in Neurologic Disorders

Author : Joseph I. Tracy
Publisher : Oxford University Press, USA
ISBN 13 : 0199965242
Total Pages : 433 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis Cognitive Plasticity in Neurologic Disorders by : Joseph I. Tracy

Download or read book Cognitive Plasticity in Neurologic Disorders written by Joseph I. Tracy and published by Oxford University Press, USA. This book was released on 2014-12-02 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume makes clear that the cognitive and behavioural symptoms of neurologic disorders and syndromes are dynamic and changing. Each chapter describes the neuroplastic processes at work in a particular condition, giving rise to these ongoing cognitive changes.

Indexes to the Epilepsy Accessions of the Epilepsy Information System

Author : J. Kiffin Penry
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (796 download)

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Book Synopsis Indexes to the Epilepsy Accessions of the Epilepsy Information System by : J. Kiffin Penry

Download or read book Indexes to the Epilepsy Accessions of the Epilepsy Information System written by J. Kiffin Penry and published by . This book was released on 1978 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Epilepsy

Author : W. Allen Hauser
Publisher : Demos Medical Publishing
ISBN 13 :
Total Pages : 402 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Epilepsy by : W. Allen Hauser

Download or read book Epilepsy written by W. Allen Hauser and published by Demos Medical Publishing. This book was released on 1990 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Epilepsy in the Elderly

Author : Günter Krämer
Publisher : Thieme
ISBN 13 : 9780865778962
Total Pages : 246 pages
Book Rating : 4.7/5 (789 download)

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Book Synopsis Epilepsy in the Elderly by : Günter Krämer

Download or read book Epilepsy in the Elderly written by Günter Krämer and published by Thieme. This book was released on 1999 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides a systematic description of the advantages and disadvantages of individual drugs for the elderly and provides orientation by means of numerous tables which list, among others, drug interactions and special features in cases of liver and kidney disease, including hemodialysis.

The Causes of Epilepsy

Author : Simon Shorvon
Publisher : Cambridge University Press
ISBN 13 : 1108420753
Total Pages : 1013 pages
Book Rating : 4.1/5 (84 download)

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Book Synopsis The Causes of Epilepsy by : Simon Shorvon

Download or read book The Causes of Epilepsy written by Simon Shorvon and published by Cambridge University Press. This book was released on 2019-05-02 with total page 1013 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expanded and revised, this unique book provides concise descriptions of the many causes of epilepsy, for use in clinical practice.

Invasive Studies of the Human Epileptic Brain

Author : Samden D. Lhatoo
Publisher : Oxford University Press, USA
ISBN 13 : 0198714661
Total Pages : 577 pages
Book Rating : 4.1/5 (987 download)

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Book Synopsis Invasive Studies of the Human Epileptic Brain by : Samden D. Lhatoo

Download or read book Invasive Studies of the Human Epileptic Brain written by Samden D. Lhatoo and published by Oxford University Press, USA. This book was released on 2019-01-22 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: No other neurological condition allows the same opportunities for an intracranial electrophysiological study of the human brain as epilepsy does. Epileptic surgery is designed to remove the epileptic focus from the human brain, thereby effecting either cure or substantial reduction of seizures in an individual with an otherwise intractable condition. Its use as a treatment modality dates from the late 19th century, and it has become a widely used treatment option throughout the world in the last 20-30 years. The complexity of epilepsy cases in surgical centres, and the need for invasive electrode studies for pre-surgical evaluation, are both greatly increasing. Invasive Studies of the Human Epileptic Brain is the definitive reference text on the use of invasive electroencephalographic (EEG) diagnostic studies in human epilepsy. Written by some of the most renowned epilepsy experts of the 20th and 21st centuries, the authors provide their expertise and insights into the identification and mapping of intracranial epileptiform and non-epileptiform activity, mapping of the human brain function, and approaches in the use of invasive electroencephalography in a variety of clinical situations. The book is organized into an easily readable series of chapters and is brilliantly illustrated with case studies; each providing an intuitively comprehensive approach to invasive brain studies.