Neonatal And Paediatric Clinical Neurophysiology

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Neonatal and Paediatric Clinical Neurophysiology

Author : Ronit Pressler
Publisher : Churchill Livingstone
ISBN 13 : 9780443101731
Total Pages : 362 pages
Book Rating : 4.1/5 (17 download)

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Book Synopsis Neonatal and Paediatric Clinical Neurophysiology by : Ronit Pressler

Download or read book Neonatal and Paediatric Clinical Neurophysiology written by Ronit Pressler and published by Churchill Livingstone. This book was released on 2007 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neonatal and Paediatric Neurophysiology is derived and updated from the hugely successful definitive text reference, Clinical Neurophysiology 2/e. Both publications have been prepared by experts of international renown, and follow a tradition of multidisciplinary team effort - with a strong foundation in neuroanatomy and neurophysiology, high standards of practical technological skills, as well as those deriving from considerable experience in the clinical neurosciences. This book is concerned with the specific technological and interpretative aspects of clinical neurophysiological recordings that are peculiar to the child from birth to adolescence. A general introduction details some general departmental procedures that are helpful when running a service for children. Methodology and maturational features for EEG, evoked potential and EMG investigations in infants and children are covered in the book. The chapters on the neurophysiology of the neonatal period and that of the child include a disease-orientated approach to the applications of the techniques. Some applications of evoked potentials and EMG, particular to these age groups, complete the coverage. Neonatal and Paediatric Clinical Neurophysiology provides a comprehensive guide for neonatologists, paediatric neurologists, clinical neurophysiologists and paediatricians. The book is also relevant to biomedical engineers involved in the design of equipment and to technicians. Specifically tailored for neonatologists, paediatric neurologists, paediatricians, clinical neurophysiologists and the associated specialist technologists working with the relevant teams Four-colour artworks and tables summarizing key aspects of information Prepared by international multidisciplinary team of leading experts offering insight and expertise in all aspects of the discipline

Pediatric Neurology

Author : E. Steve Roach, MD
Publisher : Springer Publishing Company
ISBN 13 : 0826143997
Total Pages : 515 pages
Book Rating : 4.8/5 (261 download)

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Book Synopsis Pediatric Neurology by : E. Steve Roach, MD

Download or read book Pediatric Neurology written by E. Steve Roach, MD and published by Springer Publishing Company. This book was released on 2021-09-09 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: “This book is highly recommended for those who will engage with pediatric patients as an excellent starting point to learning most clinically relevant management." ---Doody's Review Service, 3 stars Comprehensive and accessible, Pediatric Neurology is the first reference designed for trainees and nonspecialists in search of targeted information on the diagnosis and management of neurologic conditions in children. Providing a broad window on the primary disorders seen in childhood, this book interweaves the expertise of field leaders from top national institutions to concisely distill the foundations of clinical pediatric neurology. Complete with up-to-date disease guidelines and evidence-based treatment recommendations, this book serves as a starting point for physicians and other health professionals who wish to delve into fundamentals of current pediatric neurology practice. Beginning with an overview of the clinical assessment of infants and children, the book features dedicated chapters to all major disorders and conditions likely to be encountered in the pediatric population. Chapters include current information on epidemiology, clinical manifestations, diagnosis, and approaches to management for each condition in addition to tables summarizing key takeaways and detailed illustrations. Using plain language and a clear presentation of information throughout, the book is packed with the clinical wisdom needed for tackling such a complex field. With special emphasis on essential patient care concepts, Pediatric Neurology is the trusted resource for residents, general neurologists, pediatricians, medical students, and other practitioners who care for children and adolescents with neurological disease. Key Features: Introduces the foundations of clinical pediatric neurology Multi-purpose resource for point-of-care use, clinical rotations, or board preparation Organized by disease category to enhance accessibility and retrieval of key information Features chapters written by leading educators and clinicians in the field Incorporates up-to-date disease guidelines, latest FDA-approved drugs, and evidence-based treatment recommendations Purchase includes digital access for use on most mobile devices or computers

Atlas of Pediatric and Neonatal ICU EEG

Author : Arnold J. Sansevere, MD
Publisher : Springer Publishing Company
ISBN 13 : 0826148670
Total Pages : 598 pages
Book Rating : 4.8/5 (261 download)

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Book Synopsis Atlas of Pediatric and Neonatal ICU EEG by : Arnold J. Sansevere, MD

Download or read book Atlas of Pediatric and Neonatal ICU EEG written by Arnold J. Sansevere, MD and published by Springer Publishing Company. This book was released on 2020-12-28 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atlas of Pediatric and Neonatal ICU EEG is the first and only atlas to provide a comprehensive overview of the EEG patterns encountered in critically ill neonates and children, with emphasis on their significance and implications for patient care. EEG monitoring is an essential component of neurocritical care, and the patterns seen in critically ill children and neonates are often distinctly different from those found in critically ill adults or encountered in an epilepsy monitoring unit or outpatient neurophysiology laboratory. This resource provides expert guidance in the interpretation of neonatal and pediatric critical care EEG with hundreds of examples and detailed descriptions to enhance understanding and facilitate better outcomes for EEG monitoring in children. The chapters begin by addressing the basics of each topic before focusing on specific EEG patterns and their relevance to a particular disease state. Dedicated chapters on rhythmic and periodic patterns, status epilepticus, quantitative EEG analysis, and multimodality monitoring provide a thorough grounding in ICU EEG skills and applications. The book concludes with a series of thirteen cases illustrating common scenarios to help clinicians apply lessons learned. 140 board-style questions targeting information covered on the epilepsy and clinical neurophysiology boards is included online along with 12 videos that further amplify chapter content. Incorporating the most recent American Clinical Neurophysiology Society guidelines for critical care EEG monitoring in neonates and children, this evidence-based atlas will be a trusted reference for critical care clinicians, neurologists, epileptologists, and other providers who care for critically ill neonates and children. Key Features: Detailed descriptions of the indications for and utility of ICU EEG monitoring in neonatal and pediatric patients Over 270 images of neonatal and pediatric ICU EEGs with explanations of key features Illustrative cases, board-style review questions with rationales, and videos facilitate understanding and application of the material covered in the images and text Takeaway points included at the end of chapters underscore essential information

Clinical Neurophysiology in Pediatrics

Author : Gloria M. Galloway
Publisher : Springer Publishing Company
ISBN 13 : 1617052116
Total Pages : 297 pages
Book Rating : 4.6/5 (17 download)

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Book Synopsis Clinical Neurophysiology in Pediatrics by : Gloria M. Galloway

Download or read book Clinical Neurophysiology in Pediatrics written by Gloria M. Galloway and published by Springer Publishing Company. This book was released on 2015-09-08 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book to comprehensively address neurodiagnostic testing for the broad scope of clinical neurophysiologic disorders in the pediatric population. The field of clinical neurophysiology has expanded exponentially with the development of new approaches, techniques, studies, and certifications. This book bridges the gap in clinical information available for practitioners who use neurophysiologic techniques to evaluate and treat children and adolescents with epilepsy, sleep, neuromuscular, and autonomic disorders but may not have subspecialty training in each individual field. Drawing on the expertise and clinical wisdom of leading practitioners and researchers in each area of clinical neurophysiology, the book focuses on the technical and interpretive skills unique to treating the pediatric population. It covers the full spectrum of neurophysiologic topics including pediatric sleep disorders, epilepsy, febrile seizures and nonepileptic paraxosysmal disorders. Chapters address pediatric muscular dystrophies, EMG, brachial plexopathies, peripheral neuropathy, intraoperative monitoring, evoked potentials, evaluation of autonomic disorders, and EMG studies for all applications. This singular working reference will be indispensable for the clinical provider as well as for trainees and technologists who use a wide diversity of clinical neurophysiologic skills to more accurately diagnose and treat neurologic disorders in children and adolescents. Key Features: Delivers comprehensive information on all areas of pediatric clinical neurophysiology Provides clinical and procedural guidance for performing and interpreting neurodiagnostic tests in children and adolescents Over 100 illustrations of studies and findings amplify the text Brings together experts from the fields of epilepsy, sleep, neuromuscular and autonomic disorders, and neurophysiological monitoring About the Editor: Gloria M. Galloway, MD, FAAN is Professor of Clinical Neurology, Ohio State University Medical Center, Columbus, OH

Comprehensive Clinical Neurophysiology

Author : Kerry H. Levin
Publisher : Saunders
ISBN 13 :
Total Pages : 648 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Comprehensive Clinical Neurophysiology by : Kerry H. Levin

Download or read book Comprehensive Clinical Neurophysiology written by Kerry H. Levin and published by Saunders. This book was released on 2000 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading authorities in the field present a comprehensive, clinically focused text on all major aspects of electrodiagnosis in neurology. Serves as a practical daily resource for the clinician as well as an excellent study tool for board preparation in neurology and subspecialty status in neurophysiology. Topics in this generously illustrated text include basic neurophysiology, electromyography, autonomic testing, electroencephalography, evoked potentials and much more!

Techniques in Clinical Neurophysiology

Author : Ray Cooper (BSc, PhD.)
Publisher : Churchill Livingstone
ISBN 13 :
Total Pages : 444 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Techniques in Clinical Neurophysiology by : Ray Cooper (BSc, PhD.)

Download or read book Techniques in Clinical Neurophysiology written by Ray Cooper (BSc, PhD.) and published by Churchill Livingstone. This book was released on 2005 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Techniques In Clinical Neurophysiology - A Practical Manual provides a comprehensive guide for practicing neurotechnologists and those working toward higher qualifications and for clinical scientists (including neurophysiologists and neuropsychologists), and it is relevant to biomedical engineers involved in design of equipment."--BOOK JACKET.

The Epilepsies

Author : Chrysostomos P. Panayiotopoulos
Publisher : Springer
ISBN 13 :
Total Pages : 570 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Epilepsies by : Chrysostomos P. Panayiotopoulos

Download or read book The Epilepsies written by Chrysostomos P. Panayiotopoulos and published by Springer. This book was released on 2005 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives an exhaustive account of the classification and management of epileptic disorders. It provides clear didactic guidance on the diagnosis and treatment of epileptic syndromes and seizures through thirteen chapters, complemented by a pharmacopoeia and CD ROM of video-EEGs.

Clinical Neurophysiology: Basis and Technical Aspects

Author :
Publisher : Elsevier
ISBN 13 : 0444640339
Total Pages : 624 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Clinical Neurophysiology: Basis and Technical Aspects by :

Download or read book Clinical Neurophysiology: Basis and Technical Aspects written by and published by Elsevier. This book was released on 2019-07-03 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Neurophysiology: Basis and Technical Aspects, the latest release in the Handbook of Clinical Neurology series, is organized into sections on basic physiological concepts, on the function and limitations of modern instrumentation, and on other fundamental or methodologic aspects related to the recording of various bioelectric signals from the nervous system for clinical or investigative purposes. There is discussion of the EEG, nerve conduction studies, needle electromyography, intra-operative clinical neurophysiology, sleep physiology and studies, the autonomic nervous system, various sensory evoked potentials, and cognitive neurophysiology. - Provides an up-to-date review on the practice of neurophysiological techniques in the assessment of neurological disease - Explores the electrophysiological techniques used to better understand neurological function and dysfunction, first in the area of consciousness and epilepsy, then in the areas of the peripheral nervous system and sleep - Focuses on new techniques, including electrocorticography, functional mapping, stereo EEG, motor evoked potentials, magnetoencephalography, laser evoked potentials, and transcranial magnetic stimulation

Guidelines on Neonatal Seizures

Author : World Health Organization
Publisher :
ISBN 13 : 9789241548304
Total Pages : 95 pages
Book Rating : 4.5/5 (483 download)

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Book Synopsis Guidelines on Neonatal Seizures by : World Health Organization

Download or read book Guidelines on Neonatal Seizures written by World Health Organization and published by . This book was released on 2013-11-05 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neonatal seizures represent one of the most frequent neurological events in newborn infants, often reflecting a variety of different pre-, peri-, or postnatal disorders of the central nervous system (CNS). They are also a common manifestation of metabolic abnormality in newborn period and often represent the first sign of neurological dysfunction in neonates. They may be symptomatic or cryptogenic, herald subsequent epilepsy, can be associated with potential morbidity and mortality, and may be used as a factor in considering long-term prognosis. Despite the enormous clinical significance of these events, many aspects of their management are not well supported with evidence- based recommendations. These guidelines are intended to be of use for neonatologists, paediatric neurologists, paediatricians, general practitioners, nurse practitioners, nurses and other health professionals who may be in contact with infants experiencing seizures within the first 28 days of life (age up to 44 weeks postconception). The guidelines are framed so as to be applied by health care providers practicing in a wide range of health care facilities, from those with limited resources to tertiary care centers.

Pediatric Neurology

Author : Kenneth F. Swaiman
Publisher : Elsevier Health Sciences
ISBN 13 : 0323033652
Total Pages : 2535 pages
Book Rating : 4.3/5 (23 download)

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Book Synopsis Pediatric Neurology by : Kenneth F. Swaiman

Download or read book Pediatric Neurology written by Kenneth F. Swaiman and published by Elsevier Health Sciences. This book was released on 2006-01-01 with total page 2535 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Gold Standard in clinical child neurology presents the entire specialty in the most comprehensive, authoritative, and clearly written fashion. Its clinical focus, along with relevant science, throughout is directed at both the experienced clinician and the physician in training. New editor, Dr. Ferriero brings expertise in neonatal neurology to the Fourth Edition. New chapters: Pathophysiology of Hypoxic Ischemic Encephalopathy, Congenital Disorders of Glycosylation, Pediatric Neurotransmitter Diseases, Neurophysiology of Epilepsy, Genetics of Epilepsy, Pediatric Neurorehabilitation Medicine, Neuropsychopharmacology, Pain and Palliative Care Management, Ethical Issues in Child Neurology

The Clinical Neurophysiology Primer

Author : Andrew S. Blum
Publisher : Springer Science & Business Media
ISBN 13 : 1597452718
Total Pages : 515 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis The Clinical Neurophysiology Primer by : Andrew S. Blum

Download or read book The Clinical Neurophysiology Primer written by Andrew S. Blum and published by Springer Science & Business Media. This book was released on 2007-09-26 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a broad yet focused treatment of central topics in the field of clinical neurophysiology. The volume was inspired by the clinical neurophysiology lecture series at Beth Israel-Deaconess Medical Center and Rhode Island Hospital. Much like the lecture series, this book is designed to acquaint trainees with the essential elements of clinical neurophysiology. Each chapter is written by leading and respected clinical neurophysiologists.

Inherited Metabolic Epilepsies

Author : Phillip L. Pearl, MD
Publisher : Demos Medical Publishing
ISBN 13 : 1617050563
Total Pages : 377 pages
Book Rating : 4.6/5 (17 download)

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Book Synopsis Inherited Metabolic Epilepsies by : Phillip L. Pearl, MD

Download or read book Inherited Metabolic Epilepsies written by Phillip L. Pearl, MD and published by Demos Medical Publishing. This book was released on 2012-10-04 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: The explosion of information in neurogenetics and metabolism mandates increasing awareness of appropriate diagnostic and therapeutic strategies in the setting of certain epilepsies, especially those of very early onset. There are over 200 inherited disorders that are associated with seizures and prompt identification and intervention is crucial for a positive outcome. This text brings together leading authorities presenting state-of-the-art clinical reviews covering the science, recognition, and treatment of the inherited metabolic epilepsies and related disorders. Inherited Metabolic Epilepsies opens with a section on general principles for diagnosis and targeted intervention including screening protocols, laboratory testing, neuroimaging, seizure patterns and EEG findings, new technologies, and the ketogenic diet in metabolic epilepsies. The next two sections are devoted to the cohort of specific small molecule disorders (aminoacidopathies, organic acidopathies, mitochondrial disorders, urea cycle disorders, neurotransmitter disorders, and glucose-related disorders) and large molecule disorders (lysomal storage disorders, peroxisomal diseases, glycosylation defects, and leukodystrophies) that are treatable yet can be so vexing to clinicians and investigators. The book concludes with a clinical algorithm designed to be a resource for the physician in search of direction when considering an inherited metabolic disorder as the explanation for a patient with epilepsy. Inherited Metabolic Epilepsies Key Features: Presents the latest scientific thinking and clinical wisdom for a poorly understood group of disorders that have devastating consequences if unrecognized or not promptly treated Expert authorship from both the genetic-metabolic and epilepsy communities provides state-of-the-art guidance for understanding and managing these disorders A readable text for clinicians highlighting the relation between metabolic errors and epilepsy Concludes with a practical algorithm for evaluating a patient with a possible metabolic epilepsy

Pediatric Neurocritical Care

Author : Nicholas S. Abend, MD
Publisher : Demos Medical Publishing
ISBN 13 : 1617050695
Total Pages : 529 pages
Book Rating : 4.6/5 (17 download)

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Book Synopsis Pediatric Neurocritical Care by : Nicholas S. Abend, MD

Download or read book Pediatric Neurocritical Care written by Nicholas S. Abend, MD and published by Demos Medical Publishing. This book was released on 2012-11-28 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Pediatric Neurocritical Care is by far the most comprehensive book I have read dealing with this topic... This text will provide an excellent reference for those interested in the pediatric intensive care cases or pediatrics in general. It is written very well and is chock-full of information that Practioners in a pediatric ICU setting would use." --Donna Jacobs, R. EEG T., CNIM, The Neurodiagnostic Journal Caring for children with neurocritical illness often requires multi-specialty collaboration and the understanding of an ever-expanding body of data. This book gives clinicians the up-to-date, concise, and clinically relevant guidance they need to provide optimal care to children with these acute neurologic disorders. The chapters in Pediatric Neurocritical Care are authored by experts in each individual topic, and co-edited by a neurologist and intensivist to ensure that all topics have been fully addressed from both perspectives. The book covers the complete continuum of care from assessment, monitoring, and condition specific management through rehabilitation. Early chapters present differential diagnosis and management approaches to common overarching problems such as coma, headache, and elevated intracranial pressure, followed by chapters focusing on the evaluation and management of specific conditions including traumatic brain injury, stroke, seizures, central nervous system infections, and demyelinating disorders. The final chapters address important associated psychological, social, and ethical issues. To reflect the full spectrum of specialties involved in the burgeoning field of pediatric neurocritical care, the book brings together an international group of experts from multiple disciplines including critical care medicine, anesthesiology, neurology, neurosurgery, rehabilitation medicine, psychology, and pediatric subspecialties. Pediatric Neurocritical Care features: Every topic is addressed from a neurologic and critical care perspective. Comprehensive coverage includes the evaluation of common overarching problems and management of specific conditions, in addition to discussion of related psychological, ethical, and social issues. Chapters are written by internationally known experts from the fields of critical care medicine, anesthesiology, neurology, neurosurgery, rehabilitation medicine, and many affiliated specialties.

ACoRN: Acute Care of At-Risk Newborns

Author : Jill E. Boulton
Publisher : Oxford University Press
ISBN 13 : 0197525229
Total Pages : 473 pages
Book Rating : 4.1/5 (975 download)

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Book Synopsis ACoRN: Acute Care of At-Risk Newborns by : Jill E. Boulton

Download or read book ACoRN: Acute Care of At-Risk Newborns written by Jill E. Boulton and published by Oxford University Press. This book was released on 2021-04-08 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Acute Care of at-Risk Newborns (ACoRN) program trains health care providers to stabilize that most challenging and enigmatic of medical patients: the unwell newborn.Early assessment, intervention, and management of at-risk or unstable infants can be critical for their survival and long-term health. Clinical care standards and educational programs to address these requirements are needed. The ACoRN program provides a unique, prioritized, and systematic approachto newborn stabilization for health care professionals (HCPs) with any degree of experience. ACoRN-trained providers learn to gather information, prioritize, intervene appropriately, and deliver high quality care to at-risk and unwell newborns in any setting.Because research and practice have advanced dramatically in recent years, the need for a new ACoRN text, the program's centrepiece, became essential: hence the development of this new edition, which reflects current guidelines and evidence-based best practices.ACoRN teaches the concepts and skills required to stabilize unwell newborns through system-based algorithms ('Sequences'), each with its own chapter:- Respiratory- Neurology- Surgical Conditions- Cardiovascular- Fluid and Glucose- Jaundice- Thermoregulation- InfectionThe ACoRNS pneumonic defines stabilization steps and chapter structure: Alerting Signs, Core Steps, Organization of Care, Response, Next Steps, and Specific Diagnosis and Management. Each chapter includes educational objectives, key concepts, learning points, and at least one case scenario withquestions and answers to reinforce content and learnings.This book is written for any health professional who may be required to participate in the stabilization of sick or preterm babies within their scope of practice.The Canadian Paediatric Society (CPS) has worked to improve the health of children and youth since 1922. Backed by the expertise of more than 3,000 paediatricians, the CPS makes sure that parents and professionals have the best possible information about child and youth health and well-being. TheCPS is also involved in advocacy, research and education for health care providers.

Oxford Textbook of Clinical Neurophysiology

Author : Kerry R. Mills
Publisher : Oxford University Press
ISBN 13 : 0199688397
Total Pages : 481 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis Oxford Textbook of Clinical Neurophysiology by : Kerry R. Mills

Download or read book Oxford Textbook of Clinical Neurophysiology written by Kerry R. Mills and published by Oxford University Press. This book was released on 2017 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the Oxford Textbooks in Clinical Neurology series, the Oxford Textbook of Clinical Neurophysiology includes sections that provide a summary of the basic science underlying neurophysiological techniques, a description of the techniques themselves, including normal values, and a description of the use of the techniques in clinical situations. Much of diagnostic neurophysiology is essentially pattern recognition which is illustrated throughout the text using audio and video examples. Divided into four key sections, this book begins with the scientific basis of clinical neurophysiology (Section 1) before exploring specific techniques including Electromyography, Intracranial EEG recordings, and Magnetoencephalography (Section 2). The final two sections explore clinical aspects of both the peripheral nervous system (Section 3) and the central nervous system (Section 4).

Essentials of Anesthesia for Infants and Neonates

Author : Mary Ellen McCann
Publisher : Cambridge University Press
ISBN 13 : 1107069777
Total Pages : 465 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Essentials of Anesthesia for Infants and Neonates by : Mary Ellen McCann

Download or read book Essentials of Anesthesia for Infants and Neonates written by Mary Ellen McCann and published by Cambridge University Press. This book was released on 2018-02-22 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical, comprehensive guide to the special needs of infants and neonates undergoing anesthesia.

Pediatric Neurology, Part I

Author : Olivier Dulac
Publisher : Newnes
ISBN 13 : 0444626980
Total Pages : 893 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Pediatric Neurology, Part I by : Olivier Dulac

Download or read book Pediatric Neurology, Part I written by Olivier Dulac and published by Newnes. This book was released on 2013-04-24 with total page 893 pages. Available in PDF, EPUB and Kindle. Book excerpt: The child is neither an adult miniature nor an immature human being: at each age, it expresses specific abilities that optimize adaptation to its environment and development of new acquisitions. Diseases in children cover all specialties encountered in adulthood, and neurology involves a particularly large area, ranging from the brain to the striated muscle, the generation and functioning of which require half the genes of the whole genome and a majority of mitochondrial ones. Human being nervous system is sensitive to prenatal aggression, is particularly immature at birth and development may be affected by a whole range of age-dependent disorders distinct from those that occur in adults. Even diseases more often encountered in adulthood than childhood may have specific expression in the developing nervous system. The course of chronic neurological diseases beginning before adolescence remains distinct from that of adult pathology – not only from the cognitive but also motor perspective, right into adulthood, and a whole area is developing for adult neurologists to care for these children with persisting neurological diseases when they become adults. Just as pediatric neurology evolved as an identified specialty as the volume and complexity of data became too much for the general pediatician or the adult neurologist to master, the discipline has now continued to evolve into so many subspecialties, such as epilepsy, neuromuscular disease, stroke, malformations, neonatal neurology, metabolic diseases, etc., that the general pediatric neurologist no longer can reasonably possess in-depth expertise in all areas, particularly in dealing with complex cases. Subspecialty expertise thus is provided to some trainees through fellowship programmes following a general pediatric neurology residency and many of these fellowships include training in research. Since the infectious context, the genetic background and medical practice vary throughout the world, this diversity needs to be represented in a pediatric neurology textbook. Taken together, and although brain malformations (H. Sarnat & P. Curatolo, 2007) and oncology (W. Grisold & R. Soffietti) are covered in detail in other volumes of the same series and therefore only briefly addressed here, these considerations justify the number of volumes, and the number of authors who contributed from all over the world. Experts in the different subspecialties also contributed to design the general framework and contents of the book. Special emphasis is given to the developmental aspect, and normal development is reminded whenever needed – brain, muscle and the immune system. The course of chronic diseases into adulthood and ethical issues specific to the developing nervous system are also addressed. - A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world's most comprehensive source of information in neurology - International list of contributors including the leading workers in the field - Describes the advances which have occurred in clinical neurology and the neurosciences, their impact on the understanding of neurological disorders and on patient care