Natural Biomarkers for Cellular Metabolism

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Publisher : CRC Press
ISBN 13 : 1466509996
Total Pages : 404 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Natural Biomarkers for Cellular Metabolism by : Vladimir V. Ghukasyan

Download or read book Natural Biomarkers for Cellular Metabolism written by Vladimir V. Ghukasyan and published by CRC Press. This book was released on 2014-09-26 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the Lab to Clinical Settings-Advances in Quantitative, Noninvasive Optical DiagnosticsNoninvasive fluorescence imaging techniques, novel fluorescent labels, and natural biomarkers are revolutionizing our knowledge of cellular processes, signaling and metabolic pathways, the underlying mechanisms for health problems, and the identification of n

Natural Biomarkers for Cellular Metabolism

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Author :
Publisher : CRC Press
ISBN 13 : 1466509988
Total Pages : 412 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Natural Biomarkers for Cellular Metabolism by : Vladimir V. Ghukasyan

Download or read book Natural Biomarkers for Cellular Metabolism written by Vladimir V. Ghukasyan and published by CRC Press. This book was released on 2014-09-26 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the Lab to Clinical Settings—Advances in Quantitative, Noninvasive Optical Diagnostics Noninvasive fluorescence imaging techniques, novel fluorescent labels, and natural biomarkers are revolutionizing our knowledge of cellular processes, signaling and metabolic pathways, the underlying mechanisms for health problems, and the identification of new therapeutic targets for drug discoveries. Natural Biomarkers for Cellular Metabolism: Biology, Techniques, and Applications delves into the current state of knowledge on intrinsic fluorescent biomarkers and highlights recent developments in using these biomarkers for the metabolic mapping and clinical diagnosis of healthy and diseased cells and tissues. Autofluorescent Biomarkers for Biomedical Diagnostics The book’s first section introduces the fundamentals of cellular energy metabolism as well as natural biomarkers within the context of their biological functions. The second section outlines the theoretical and technical background of quantitative, noninvasive, autofluorescence microscopy and spectroscopy methods, including experimental design, calibration, pitfalls, and remedies of data acquisition and analysis. The last two sections highlight advances in biomedical and biochemical applications, such as monitoring stem cell differentiation in engineered tissues and diagnosing cancer and ophthalmic diseases quantitatively and noninvasively. Tailored to Interdisciplinary Researchers Covering cell biology, imaging techniques, and clinical diagnostics, this book provides readers with a complete guide to studying cellular/tissue metabolism under healthy, diseased, and environment-induced stress conditions using natural biomarkers. The book is designed for graduate and advanced undergraduate students, biophysics instructors, medical researchers, and those in pharmaceutical R&D.

Monitoring Metabolic Status

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Publisher : National Academies Press
ISBN 13 : 0309091594
Total Pages : 469 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Monitoring Metabolic Status by : Institute of Medicine

Download or read book Monitoring Metabolic Status written by Institute of Medicine and published by National Academies Press. This book was released on 2004-08-29 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: The U.S. military's concerns about the individual combat service member's ability to avoid performance degradation, in conjunction with the need to maintain both mental and physical capabilities in highly stressful situations, have led to and interest in developing methods by which commanders can monitor the status of the combat service members in the field. This report examines appropriate biological markers, monitoring technologies currently available and in need of development, and appropriate algorithms to interpret the data obtained in order to provide information for command decisions relative to the physiological "readiness" of each combat service member. More specifically, this report also provides responses to questions posed by the military relative to monitoring the metabolic regulation during prolonged, exhaustive efforts, where nutrition/hydration and repair mechanisms may be mismatched to intakes and rest, or where specific metabolic derangements are present.

Carotid Artery

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Publisher : BoD – Books on Demand
ISBN 13 : 1789849810
Total Pages : 128 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Carotid Artery by : Rita Rezzani

Download or read book Carotid Artery written by Rita Rezzani and published by BoD – Books on Demand. This book was released on 2019-09-18 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book collects recent experimental and clinical studies on gender influence in carotid artery compliance in health and pathological states, discussing also the usefulness and appropriateness of specific and personal medical therapy. Additionally, it provides an overview of the growing importance of ongoing studies on the benefit and risk of gender-specific therapy.

Imaging from Cells to Animals In Vivo

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Publisher : CRC Press
ISBN 13 : 1351704494
Total Pages : 444 pages
Book Rating : 4.3/5 (517 download)

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Book Synopsis Imaging from Cells to Animals In Vivo by : Margarida Barroso

Download or read book Imaging from Cells to Animals In Vivo written by Margarida Barroso and published by CRC Press. This book was released on 2020-12-03 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers an overview of imaging techniques used to investigate cells and tissue in their native environment. It covers the range of imaging approaches used, as well as the application of those techniques to the study of biological processes in cells and whole tissues within living organisms.

Multiphoton Microscopy and Fluorescence Lifetime Imaging

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Author :
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110429985
Total Pages : 450 pages
Book Rating : 4.1/5 (14 download)

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Book Synopsis Multiphoton Microscopy and Fluorescence Lifetime Imaging by : Karsten König

Download or read book Multiphoton Microscopy and Fluorescence Lifetime Imaging written by Karsten König and published by Walter de Gruyter GmbH & Co KG. This book was released on 2018-01-22 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph demonstrates the latest developments in two-photon fluorescence microscopy and second-harmonic generation (SHG) microscopy, including coverage of high-resolution microscopy methods, such as STED microscopy. A special focus lies on clinical applications of these methods, e.g. in dermatology, ophtalmology, neuro sciences and cell biology.

The Heterogeneity of Cancer Metabolism

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Publisher : Springer
ISBN 13 : 331977736X
Total Pages : 186 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis The Heterogeneity of Cancer Metabolism by : Anne Le

Download or read book The Heterogeneity of Cancer Metabolism written by Anne Le and published by Springer. This book was released on 2018-06-26 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.

Biomarkers for Huntington's Disease

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Author :
Publisher : Springer Nature
ISBN 13 : 3031328159
Total Pages : 476 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Biomarkers for Huntington's Disease by : Elizabeth A. Thomas

Download or read book Biomarkers for Huntington's Disease written by Elizabeth A. Thomas and published by Springer Nature. This book was released on 2023-11-13 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Huntington’s disease (HD) is a fatal, inherited, neurodegenerative disorder, characterized by chorea, motor instabilities, psychiatric manifestations and cognitive decline. Early genetic testing provides an opportunity for clinical interventions aimed at delaying onset and/or slowing progression of disease; however, current treatments for HD are limited, with only two FDA-approved drugs available to manage chorea. Encouragingly, however, several disease-modifying treatment approaches are in the therapeutic pipeline, with more than 200 clinical studies, and many more preclinical studies, in the works. Robust and reliable biomarkers are needed to predict disease onset, monitor disease progression and assess treatment responses. More specifically, biomarkers to stratify patients for clinical trials and biomarkers to track drug efficacy will certainly lead to improved clinical trial design and success. This book represents the first book focused solely on biomarkers for HD and represents a distinct resource that will be informative, not only for clinicians and those involved in clinical trial design, but also for a wide range of neurodegenerative disease researchers. This edited volume is written by top leaders in the field, and takes a cross-disciplinary approach to cover a broad spectrum of biomarker types, in order to provide the latest advances in the development of biochemical, molecular, imaging and digital biomarkers that have been investigated for HD. With the ultimate goal of treating patients, the development of disease-associated biomarkers has never been more important.

General Methods in Biomarker Research and their Applications

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Author :
Publisher : Springer
ISBN 13 : 9789400776951
Total Pages : 0 pages
Book Rating : 4.7/5 (769 download)

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Book Synopsis General Methods in Biomarker Research and their Applications by : Victor R. Preedy

Download or read book General Methods in Biomarker Research and their Applications written by Victor R. Preedy and published by Springer. This book was released on 2015-08-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past decade there has been a major sea change in the way disease is diagnosed and investigated due to the advent of high throughput technologies, such as microarrays, lab on a chip, proteomics, genomics, lipomics, metabolomics etc. These advances have enabled the discovery of new and novel markers of disease relating to autoimmune disorders, cancers, endocrine diseases, genetic disorders, sensory damage, intestinal diseases etc. In many instances these developments have gone hand in hand with the discovery of biomarkers elucidated via traditional or conventional methods, such as histopathology or clinical biochemistry. Together with microprocessor-based data analysis, advanced statistics and bioinformatics these markers have been used to identify individuals with active disease or pathology as well as those who are refractory or have distinguishing pathologies. New analytical methods that have been used to identify markers of disease and is suggested that there may be as many as 40 different platforms. Unfortunately techniques and methods have not been readily transferable to other disease states and sometimes diagnosis still relies on single analytes rather than a cohort of markers. There is thus a demand for a comprehensive and focused evidenced-based text and scientific literature that addresses these issues. Hence the formulation of Biomarkers in Disease. The series covers a wide number of areas including for example, nutrition, cancer, endocrinology, cardiology, addictions, immunology, birth defects, genetics and so on. The chapters are written by national or international experts and specialists.

Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527835741
Total Pages : 292 pages
Book Rating : 4.5/5 (278 download)

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Book Synopsis Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines by : Aihua Zhang

Download or read book Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines written by Aihua Zhang and published by John Wiley & Sons. This book was released on 2021-08-20 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highlights the importance and benefit of mass spectrometry-based metabolomics for identifying biomarkers that accurately screen for potential biomarkers of diseases Mass spectrometry-based metabolomics offer new opportunities for biomarker discovery in complex diseases and may provide pathological understanding of diseases beyond traditional technologies. It is the systematic analysis of low-molecular-weight metabolites in biological samples and has been applied to discovering and identifying the perturbed pathways. Currently, mass spectrometry-based metabolomics has become an important tool in clinical research and the diagnosis of human disease. Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines comprehensively presents the current state, challenges, and applications of high-throughput mass spectrometry-based metabolomics such as metabolites analysis, biomarker discovery, technical challenges, discovery of natural product, mechanism interpretation of action, discovery of active ingredients, clinical application and precision medicine, and enhancing their biomedical value in a real world of biomedicine, shedding light on the potential for spectrometry-based metabolomics. It highlights the value of mass spectrometry-based metabolomics and metabolism to address the complexity of herbal medicines in systems pharmacology, especially, to link phytochemical analysis with the assessment of pharmacological effect and therapeutic potential. Each chapter has been laid out with introduction, method, up-to-date literature, identification of biomarker, and applications Covers the current state, challenges, and applications of high-throughput mass spectrometry-based metabolomics in the discovery of biomarker, active ingredients, natural product, etc. Constitutes a unique and indispensable practical guide for any phytochemistry or related laboratory, and provides hands-on description of new techniques Provides a guide for new practitioners of pharmacologists, pharmacological scholars, drug developers, botanist, researchers of traditional medicines. Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines provides a landmark of mass spectrometry-based metabolomics research and a beneficial guideline to graduate students and researchers in academia, industry, and technology transfer organizations in all biomedical science fields.

Biomarkers in Liver Disease

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Author :
Publisher : Springer
ISBN 13 : 9789400776746
Total Pages : 0 pages
Book Rating : 4.7/5 (767 download)

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Book Synopsis Biomarkers in Liver Disease by : Victor R. Preedy

Download or read book Biomarkers in Liver Disease written by Victor R. Preedy and published by Springer. This book was released on 2017-07-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past decade there has been a major sea change in the way disease is diagnosed and investigated due to the advent of high throughput technologies, such as microarrays, lab on a chip, proteomics, genomics, lipomics, metabolomics etc. These advances have enabled the discovery of new and novel markers of disease relating to autoimmune disorders, cancers, endocrine diseases, genetic disorders, sensory damage, intestinal diseases etc. In many instances these developments have gone hand in hand with the discovery of biomarkers elucidated via traditional or conventional methods, such as histopathology or clinical biochemistry. Together with microprocessor-based data analysis, advanced statistics and bioinformatics these markers have been used to identify individuals with active disease or pathology as well as those who are refractory or have distinguishing pathologies. New analytical methods that have been used to identify markers of disease and is suggested that there may be as many as 40 different platforms. Unfortunately techniques and methods have not been readily transferable to other disease states and sometimes diagnosis still relies on single analytes rather than a cohort of markers. There is thus a demand for a comprehensive and focused evidenced-based text and scientific literature that addresses these issues. Hence the formulation of Biomarkers in Disease The series covers a wide number of areas including for example, nutrition, cancer, endocrinology, cardiology, addictions, immunology, birth defects, genetics, and so on. The chapters are written by national or international experts and specialists.

Metabolic Signaling

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Publisher : Humana
ISBN 13 : 9781493987689
Total Pages : 0 pages
Book Rating : 4.9/5 (876 download)

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Book Synopsis Metabolic Signaling by : Sarah-Maria Fendt

Download or read book Metabolic Signaling written by Sarah-Maria Fendt and published by Humana. This book was released on 2018-10-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides protocols to quantify metabolism, to identify metabolic crosstalk, and to setup and develop tools and models to gain insight into metabolic signaling using experimental and computational approaches. Chapters detail protocols to quantify metabolism, identify metabolic crosstalk, and develop tools and models to gain a systems-level insight into metabolic signaling. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Metabolic Signaling: Methods and Protocols aims to provide researchers with methods to study, perturb, and functionally interpret metabolism and metabolic signaling from the sub-cellular to the whole-body level.

Chinmedomics

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Publisher : Academic Press
ISBN 13 : 0128031182
Total Pages : 408 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Chinmedomics by : Xijun Wang

Download or read book Chinmedomics written by Xijun Wang and published by Academic Press. This book was released on 2015-07-15 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chinmedomics: The Integration of Serum Pharmacochemistry and Metabolomics to Elucidate the Scientific Value of Traditional Chinese Medicine uses new experimental techniques and research to open doors in drug discovery and development related to traditional Chinese medicine (TCM). This book features a unique approach that combines chemometric analysis with metabolomics studies to illuminate significant changes that have occurred in syndrome states while simultaneously analyzing the efficacy of chemical ingredients in herbal medicines. Chapters provide cutting-edge information on traditional medicine, analytical technology, natural products, metabolomics, bioinformatics and their applications. This book provides a valuable resource for pharmacologists, pharmaceutical scientists, medicinal plant researchers, pharmacognosists and chemists working with TCM and highlights ways to further research and advances in this area in the future. Presents a practical guide for new practitioners of Chinmedomics with insights on the current use and future development of this method Each chapter includes an introduction, method, references to the latest literature, possible mechanisms of action and applications Edited by the leading experts of research related to Chinmedomics

Imaging in Cellular and Tissue Engineering

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Publisher : CRC Press
ISBN 13 : 1439848033
Total Pages : 296 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Imaging in Cellular and Tissue Engineering by : Hanry Yu

Download or read book Imaging in Cellular and Tissue Engineering written by Hanry Yu and published by CRC Press. This book was released on 2013-05-16 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Details on specific imaging modalities for different cellular and tissue engineering applications are scattered throughout articles and chapters in the literature. Gathering this information into a single reference, Imaging in Cellular and Tissue Engineering presents both the fundamentals and state of the art in imaging methods, approaches, and applications in regenerative medicine. The book underscores the broadening scope of imaging applications in cellular and tissue engineering. It covers a wide range of optical and biological applications, including the repair or replacement of whole tissues (such as bone, cartilage, blood vessels, and bladder) and more novel artificially created support systems (such as artificial pancreas and bioartificial liver). Each chapter describes a particular application, relevant optical instrumentation, physical principles governing the imaging method, and strengths and weaknesses of the technique. The book also presents current and emerging data processing procedures. As the field of tissue engineering moves from creating simpler outer body parts to more sophisticated internal organs, researchers need to evaluate and control how well the tissues are engineered and integrated into the living body. Suitable for both experts and newcomers in bioengineering and biomedical imaging, this book shows researchers how to apply imaging techniques to next-generation engineered cells and tissues. It helps them assess the suitability of specific imaging modalities for applications with various functional requirements.

Ultimate Guide to Insulin

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Author :
Publisher :
ISBN 13 : 1789849217
Total Pages : 132 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Ultimate Guide to Insulin by : Gaffar Zaman

Download or read book Ultimate Guide to Insulin written by Gaffar Zaman and published by . This book was released on 2019-02-06 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents a qualitative and quantitative approach to understand, manage and enforce the integration of insulin into diabetes mellitus. Utilizing a sound theoretical and practical foundation and illustrating procedural techniques through scientific examples, the book bridges the gap between insulin and diabetes mellitus management. Detailed procedures have been omitted because of the variety of equipment and commercial kits used in today's clinical laboratories.

Novel biomarkers for anticancer therapy

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832513859
Total Pages : 428 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Novel biomarkers for anticancer therapy by : Hongtao Xiao

Download or read book Novel biomarkers for anticancer therapy written by Hongtao Xiao and published by Frontiers Media SA. This book was released on 2023-02-07 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt:

lncRNAs in Cancer Metastasis and Therapy Resistance

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Publisher : Frontiers Media SA
ISBN 13 : 2832526128
Total Pages : 445 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis lncRNAs in Cancer Metastasis and Therapy Resistance by : Aamir Ahmad

Download or read book lncRNAs in Cancer Metastasis and Therapy Resistance written by Aamir Ahmad and published by Frontiers Media SA. This book was released on 2023-10-30 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: lncRNAs (long non-coding RNAs) are the relatively longer (more than 200 nucleotides long) subtypes of ncRNAs (non-coding RNAs) i.e the RNAs that do not code for any proteins. However, even without themselves being translated, lncRNAs impact the cellular gene expressions and functions in ways that are just beginning to be explored. The metastasis of human cancers as well as acquired resistance against the administered therapeutics are two major factors responsible for the cancer-associated mortality.