Nanoparticle Mediated Immunotherapy

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Nanoparticle-Mediated Immunotherapy

Author : Tuan Vo-Dinh
Publisher : Springer Nature
ISBN 13 : 3030783383
Total Pages : 269 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Nanoparticle-Mediated Immunotherapy by : Tuan Vo-Dinh

Download or read book Nanoparticle-Mediated Immunotherapy written by Tuan Vo-Dinh and published by Springer Nature. This book was released on 2021-10-12 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is intended to serve as an authoritative reference source for a broad audience involved in the research, teaching, learning, and practice of nanotechnology in immunotherapy. The combination of nanotechnology and immunotherapy is recognized as a promising treatment modality. In particular, the use of nanoparticles in immunotherapy has attracted increased attention for their unique efficacy and specificity in cancer treatment. A wide variety of nanoparticles, such as polymeric and liposomal nanosystems, carbon nanotubes, and gold nanoparticles have provided important nanoplatforms for immunotherapeutic approaches. They have been shown to improve delivery and efficacy of immunotherapeutic agents such as vaccines or adjuvants. Nanoparticle-mediated thermal therapy has demonstrated the effectiveness for precise tumor cell ablation, radio-sensitization of hypoxic regions, enhancement of drug delivery, activation of thermosensitive agents, and enhancement of the immune system. Plasmonic nanoparticles are a special type of metallic nanoparticles that has received great interest due to their enhanced optical and electromagnetic properties and their superior capacity to convert photon energy into heat for selective photothermal therapy at the nanoscale level. Nanoparticle sizes can also be controlled such that they accumulate preferentially in tumors due to the enhanced permeability and retention effect of tumor vasculature. Various nanosystems such as gold nanoparticles have also been shown to stimulate the immune system. Immunotherapies could thus synergistically benefit from the combination with targeted nanoparticle-mediated photothermal therapies, especially when hyperthermia around immune-checkpoint inhibitors in the tumor bed is combined with precise thermal ablation of cancer cells. Of great importance is the possibility that such an approach can induce long-term immunological memory that can provide protection against tumor recurrence long after treatment of the initial tumors, like an ‘anticancer vaccine’. Nanoparticle-mediated immunotherapy could lead to an entirely new treatment paradigm that challenges traditional surgical resection approaches for many cancers and metastases.

Nanoparticle-Mediated Signaling Rewiring and Reprogramming of Immune Responses

Author : David Pozo
Publisher : Frontiers Media SA
ISBN 13 : 2889763188
Total Pages : 172 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Nanoparticle-Mediated Signaling Rewiring and Reprogramming of Immune Responses by : David Pozo

Download or read book Nanoparticle-Mediated Signaling Rewiring and Reprogramming of Immune Responses written by David Pozo and published by Frontiers Media SA. This book was released on 2022-06-03 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Quintana is the founder of AnTolRx. The other Topic Editor declares no competing interests.

Nanobiotechnology in Diagnosis, Drug Delivery and Treatment

Author : Mahendra Rai
Publisher : John Wiley & Sons
ISBN 13 : 1119671868
Total Pages : 416 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Nanobiotechnology in Diagnosis, Drug Delivery and Treatment by : Mahendra Rai

Download or read book Nanobiotechnology in Diagnosis, Drug Delivery and Treatment written by Mahendra Rai and published by John Wiley & Sons. This book was released on 2020-11-17 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents nanobiotechnology in drug delivery and disease management Featuring contributions from noted experts in the field, this book highlights recent advances in the nano-based drug delivery systems. It also covers the diagnosis and role of various nanomaterials in the management of infectious diseases and non-infectious disorders, such as cancers and other malignancies and their role in future medicine. Nanobiotechnology in Diagnosis, Drug Delivery and Treatment starts by introducing how nanotechnology has revolutionized drug delivery, diagnosis, and treatments of diseases. It then focuses on the role of various nanocomposites in diagnosis, drug delivery, and treatment of diseases like cancer, Alzheimer's disease, diabetes, and many others. Next, it discusses the application of a variety of nanomaterials in the diagnosis and management of gastrointestinal tract disorders. The book explains the concept of nanotheranostics in detail and its role in effective monitoring of drug response, targeted drug delivery, enhanced drug accumulation in the target tissues, sustained as well as triggered release of drugs, and reduction in adverse effects. Other chapters cover aptamer-incorporated nanoparticle systems; magnetic nanoparticles; theranostics and vaccines; toxicological concerns of nanomaterials used in nanomedicine; and more. Provides a concise overview of state-of-the-art nanomaterials and their application like drug delivery in infectious diseases and non-infectious disorders Highlights recent advances in the nano-based drug delivery systems and role of various nanomaterials Introduces nano-based sensors which detect various pathogens Covers the use of nanodevices in diagnostics and theranostics Nanobiotechnology in Diagnosis, Drug Delivery and Treatment is an ideal book for researchers and scientists working in various disciplines such as microbiology, biotechnology, nanotechnology, pharmaceutical biotechnology, pharmacology, pharmaceutics, and nanomedicine.

RNA Nanotechnology

Author : Bin Wang
Publisher : CRC Press
ISBN 13 : 9814411647
Total Pages : 468 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis RNA Nanotechnology by : Bin Wang

Download or read book RNA Nanotechnology written by Bin Wang and published by CRC Press. This book was released on 2014-04-02 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past few decades there has been incredible growth in "bionano"-related research, which has been accompanied by numerous publications in this field. Although various compilations address topics related to deoxyribonucleic acid (DNA) and protein, there are few books that focus on determining the structure of ribonucleic acid (RNA) and using RNA as building blocks to construct nanoarchitectures for biomedical and healthcare applications. RNA Nanotechnology is a comprehensive volume that details both the traditional approaches and the latest developments in the field of RNA-related technology. This book targets a wide audience: a broad introduction provides a solid academic background for students, researchers, and scientists who are unfamiliar with the subject, while the in-depth descriptions and discussions are useful for advanced professionals. The book opens with reviews on the basic aspects of RNA biology, computational approaches for predicting RNA structures, and traditional and emerging experimental approaches for probing RNA structures. This section is followed by explorations of the latest research and discoveries in RNA nanotechnology, including the design and construction of RNA-based nanostructures. The final segment of the book includes descriptions and discussions of the potential biological and therapeutic applications of small RNA molecules, such as small/short interfering RNAs (siRNAs), microRNAs (miRNAs), RNA aptamers, and ribozymes.

Combinatorial Prospects of Nanoparticle Mediated Immunotherapy of Cancer

Author :
Publisher :
ISBN 13 : 9789464192339
Total Pages : 289 pages
Book Rating : 4.1/5 (923 download)

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Book Synopsis Combinatorial Prospects of Nanoparticle Mediated Immunotherapy of Cancer by :

Download or read book Combinatorial Prospects of Nanoparticle Mediated Immunotherapy of Cancer written by and published by . This book was released on 2021 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Adverse Effects of Cancer Chemotherapy: Anything New to Improve Tolerance and Reduce Sequelae?

Author : Kulmira Nurgali
Publisher : Frontiers Media SA
ISBN 13 : 2889454827
Total Pages : 245 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Adverse Effects of Cancer Chemotherapy: Anything New to Improve Tolerance and Reduce Sequelae? by : Kulmira Nurgali

Download or read book Adverse Effects of Cancer Chemotherapy: Anything New to Improve Tolerance and Reduce Sequelae? written by Kulmira Nurgali and published by Frontiers Media SA. This book was released on 2018-06-12 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in anti-cancer chemotherapy over recent years have led to improved efficacy in curing or controlling many cancers. Some chemotherapy-related side-effects are well recognized and include: nausea, vomiting, bone marrow suppression, peripheral neuropathy, cardiac and skeletal muscle dysfunction and renal impairment. However, it is becoming clearer that some chemotherapy-related adverse effects may persist even in long term cancer survivors. Problems such as cognitive, cardiovascular and gastrointestinal dysfunction, and neuropathy may lead to substantial long term morbidity. Despite improvements in treatments to counteract acute chemotherapy-induced adverse effects, they are often incompletely effective. Furthermore, counter-measures for some acute side-effects and many potential longer term sequelae of anti-cancer chemotherapy have not been developed. Thus, new insights into prevalence and mechanisms of cancer chemotherapy-related side effects are needed and new approaches to improving tolerance and reduce sequelae of cancer chemotherapy are urgently needed. The present Research Topic focuses on adverse effects and sequelae of chemotherapy and strategies to counteract them.

Bioinformatics for Cancer Immunotherapy

Author : Sebastian Boegel
Publisher : Humana
ISBN 13 : 9781071603291
Total Pages : 304 pages
Book Rating : 4.6/5 (32 download)

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Book Synopsis Bioinformatics for Cancer Immunotherapy by : Sebastian Boegel

Download or read book Bioinformatics for Cancer Immunotherapy written by Sebastian Boegel and published by Humana. This book was released on 2021-03-17 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on a variety of in silico protocols of the latest bioinformatics tools and computational pipelines developed for neo-antigen identification and immune cell analysis from high-throughput sequencing data for cancer immunotherapy. The chapters in this book cover topics that discuss the two emerging concepts in recognition of tumor cells using endogenous T cells: cancer vaccines against neo-antigens presented on HLA class I and II alleles, and checkpoint inhibitors. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Bioinformatics for Cancer Immunotherapy: Methods and Protocols is a valuable research tool for any scientist and researcher interested in learning more about this exciting and developing field.

Treatment of Leukemia and Lymphoma

Author : David A. Scheinberg
Publisher : Elsevier
ISBN 13 : 0080490409
Total Pages : 417 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Treatment of Leukemia and Lymphoma by : David A. Scheinberg

Download or read book Treatment of Leukemia and Lymphoma written by David A. Scheinberg and published by Elsevier. This book was released on 2004-10-30 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Treatments of Leukemia and Lymphoma describes the most important advances in the therapy of hematopoietic cancers that have been derived from recent discoveries in cancer cell biology, kinase biochemistry, and immunology. Detailed descriptions of the large number of new and effective agents that have recently become available for the treatment of leukemias and lymphomas as well as an understanding of their mechanisms of action and their integration into current therapy are provided. A number of experimental drug reagents currently in clinical investigation are also discussed. The therapies include conventional anti-metabolites, monoclonal antibodies directed to cell surface receptors, antibodies tagged with toxins and radiopharmaceuticals, inhibitors of specific kinases, stem cell transplants, and engineered T-cells designed to selectively target hematopoietic cancers. The contents of the book will allow practitioners and investigators alike to understand what is current and state of the art as well as what to look for in the future.* Provides an up-to-date, state of the art discussion of a rapidly changing field * Great breadth covering conventional chemotherapeutic agents, biologic agents such as antibodies, novel small molecule inhibitors and genetically engineered cells * Written by international experts in each of the fields

Bionanotechnology in Cancer

Author : D. Sakthi Kumar
Publisher : CRC Press
ISBN 13 : 0429750404
Total Pages : 592 pages
Book Rating : 4.4/5 (297 download)

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Book Synopsis Bionanotechnology in Cancer by : D. Sakthi Kumar

Download or read book Bionanotechnology in Cancer written by D. Sakthi Kumar and published by CRC Press. This book was released on 2022-10-27 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cancer research world is looking forward to bionanotechnology to find the best solutions for a complete cure from cancer, which is not possible with the current established treatment methods. The past decade of research on nano imaging and drug delivery in cancer has witnessed many interesting papers and reviews, but there has not been a concise resource that discusses all fields related to nano cancer research in diagnosis and drug delivery. This book fills this gap and presents the latest bionano research in cancer, focusing on nanodiagnostics and nanotherapy. The book is organized into two sections. The section on nanodiagnostics focuses on topics such as diagnostic methods in cancer-related therapy and use of radiolabeled nanoparticles, magnetic nanoparticles, acoustically reflective nanoparticles, X-ray computed tomography, and optical nanoprobes for diagnosis. The section on nanotherapy focuses on nanomaterials in chemotherapy, magnetic nanoparticles for hyperthermia against cancer, phototherapy, nanotechnology-mediated radiation therapy, nanoparticle-mediated small-RNA deliveries for molecular therapies, and theranostics. The book will serve as the gateway to enter the beautiful and elegant field of bionanoscience, which is considered the last hope for the fight against cancer and will be a highly useful resource for the students, researchers, teachers, and curious readers working in this field or related fields.

Induction of Immunogenic Cell Death Via Nanoparticle-mediated Dual Chemotherapy and Photothermal Therapy

Author : Niloofar Heshmati Aghda
Publisher :
ISBN 13 :
Total Pages : 220 pages
Book Rating : 4.:/5 (122 download)

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Book Synopsis Induction of Immunogenic Cell Death Via Nanoparticle-mediated Dual Chemotherapy and Photothermal Therapy by : Niloofar Heshmati Aghda

Download or read book Induction of Immunogenic Cell Death Via Nanoparticle-mediated Dual Chemotherapy and Photothermal Therapy written by Niloofar Heshmati Aghda and published by . This book was released on 2020 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is the second most common cause of mortality in the world. Several treatment modalities have been developed for cancer therapy. Recently, immune checkpoint (ICP) therapy has demonstrated promising results. However, low response rates, cancer recurrence and side effects are remaining problems. In this work, we aimed to develop formulations to enhance the effectiveness of ICP therapy which enables the patient's immune system to attack cancer cells and, consequently, requires an environment conductive to a targeted immune response against the cancer cells. To achieve this aim, we developed two types of nanoparticles (NPs) for combinatory chemo-photothermal therapy (PTT) to induce immunogenic cell death (ICD) and target the medication to the tumor site. ICD overall causes the activation of dendritic cells (DC) and T cells to initiate an antitumor immune response and is characterized by the presentation of damage associated molecular patterns (DAMPs). NPs were made from biocompatible polymers, poly(lactic acid)-b-poly(ethylene glycol) and bovine serum albumin. Both NPs were loaded with doxorubicin, a chemotherapeutic agent, and indocyanine green, a PTT agent that can absorb the light in near infrared (NIR) region and convert it to heat. NPs were characterized and confirmed to be suitable for agent delivery. Both types of NPs were shown to significantly reduce the viability of model cancer cells, MDA-MB-231 breast cancer cells and B16F10 melanoma cells, in vitro. Analysis of DAMP presentation after treatment demonstrated that NPs could induce ICD. Next, the potential of NP fabrication on a large scale was studied using a high throughput fiber reactor. Poly(lactic-co-glycolic acid) was the polymer used in scale-up studies.

Nanopharmaceuticals: Principles and Applications Vol. 3

Author : Vinod Kumar Yata
Publisher : Springer Nature
ISBN 13 : 3030471209
Total Pages : 340 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Nanopharmaceuticals: Principles and Applications Vol. 3 by : Vinod Kumar Yata

Download or read book Nanopharmaceuticals: Principles and Applications Vol. 3 written by Vinod Kumar Yata and published by Springer Nature. This book was released on 2020-08-19 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the third volume on this subject and focuses on the recent advances of nanopharmaceuticals in cancer, dental, dermal and drug delivery applications and presents their safety, toxicity and therapeutic efficacy. The book also includes the transport phenomenon of nanomaterials and important pathways for drug delivery applications. It goes on to explain the toxicity of nanoparticles to different physiological systems and methods used to assess this for different organ systems using examples of in vivo systems.

Nanostructures for Cancer Therapy

Author : Alexandru Mihai Grumezescu
Publisher : Elsevier
ISBN 13 : 0323461506
Total Pages : 922 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Nanostructures for Cancer Therapy by : Alexandru Mihai Grumezescu

Download or read book Nanostructures for Cancer Therapy written by Alexandru Mihai Grumezescu and published by Elsevier. This book was released on 2017-04-11 with total page 922 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanostructures for Cancer Therapy discusses the available preclinical and clinical nanoparticle technology platforms and their impact on cancer therapy, including current trends and developments in the use of nanostructured materials in chemotherapy and chemotherapeutics. In particular, coverage is given to the applications of gold nanoparticles and quantum dots in cancer therapies. In addition to the multifunctional nanomaterials involved in the treatment of cancer, other topics covered include nanocomposites that can target tumoral cells and the release of antitumoral therapeutic agents. The book is an up-to-date overview that covers the inorganic and organic nanostructures involved in the diagnostics and treatment of cancer. Provides an examination of nanoparticle delivery systems for cancer treatment, illustrating how the use of nanotechnology can help provide more effective chemotherapeutic treatments Examines, in detail, the different types of nanomaterials used in cancer therapy, also explaining the effect of each Provides a cogent overview of recent developments in the use of nanostructured materials in chemotherapeutics, allowing readers to quickly familiarize themselves with this area

Viral Nanoparticles

Author : Nicole F. Steinmetz
Publisher : CRC Press
ISBN 13 : 9814267945
Total Pages : 281 pages
Book Rating : 4.8/5 (142 download)

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Book Synopsis Viral Nanoparticles by : Nicole F. Steinmetz

Download or read book Viral Nanoparticles written by Nicole F. Steinmetz and published by CRC Press. This book was released on 2019-08-21 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book overviews the applications of viral nanoparticles (VNPs) in areas ranging from materials science to biomedicine. It summarizes the many different VNP building blocks and describes chemistries that allow one to attach, entrap, or display functionalities on VNPs. The book outlines the strategies for the construction of 1-, 2-, and 3-D arrays, highlights the achievements in utilizing VNPs as tools for novel biosensors and nanoelectronic devices, and describes efforts in designing VNPs for biomedical applications, including their use as gene delivery vectors, novel vaccines, imaging modalities, and applications in targeted therapeutics.

Progress in Cancer Immunotherapy

Author : Shuren Zhang
Publisher : Springer
ISBN 13 : 9401775559
Total Pages : 293 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Progress in Cancer Immunotherapy by : Shuren Zhang

Download or read book Progress in Cancer Immunotherapy written by Shuren Zhang and published by Springer. This book was released on 2016-05-30 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers an extensive overview of recent progress in basic and clinical research on cancer immunotherapy. Thanks to rapid advances in molecular biology and immunology, it has become increasingly evident that cancer growth is influenced by host immune responses. With the success of a number of clinical trials, immunotherapy has become a promising treatment modality of cancer. This book covers five major topics, including monoclonal antibodies, biological response modifiers, cancer vaccines, adoptive cellular therapy and oncolytic viruses. It also examines the combination of different immune strategies as well as the combination of immunotherapy with other treatments to increase anti-tumor effects. Through the comprehensive discussion of the topic, the book sheds valuable new light on the treatment of tumors.

Advanced Healthcare Materials

Author : Ashutosh Tiwari
Publisher : John Wiley & Sons
ISBN 13 : 1118773683
Total Pages : 421 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Advanced Healthcare Materials by : Ashutosh Tiwari

Download or read book Advanced Healthcare Materials written by Ashutosh Tiwari and published by John Wiley & Sons. This book was released on 2014-05-09 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers a comprehensive and interdisciplinary view of cutting-edge research on advanced materials for healthcare technology and applications Advanced healthcare materials are attracting strong interest in fundamental as well as applied medical science and technology. This book summarizes the current state of knowledge in the field of advanced materials for functional therapeutics, point-of-care diagnostics, translational materials, and up-and-coming bioengineering devices. Advanced Healthcare Materials highlights the key features that enable the design of stimuli-responsive smart nanoparticles, novel biomaterials, and nano/micro devices for either diagnosis or therapy, or both, called theranostics. It also presents the latest advancements in healthcare materials and medical technology. The senior researchers from global knowledge centers have written topics including: State-of-the-art of biomaterials for human health Micro- and nanoparticles and their application in biosensors The role of immunoassays Stimuli-responsive smart nanoparticles Diagnosis and treatment of cancer Advanced materials for biomedical application and drug delivery Nanoparticles for diagnosis and/or treatment of Alzheimers disease Hierarchical modelling of elastic behavior of human dental tissue Biodegradable porous hydrogels Hydrogels in tissue engineering, drug delivery, and wound care Modified natural zeolites Supramolecular hydrogels based on cyclodextrin poly(pseudo)rotaxane Polyhydroxyalkanoate-based biomaterials Biomimetic molecularly imprinted polymers

Nanomedicine for Cancer Therapy

Author : Piyush Kumar
Publisher : Springer
ISBN 13 : 3319458264
Total Pages : 77 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Nanomedicine for Cancer Therapy by : Piyush Kumar

Download or read book Nanomedicine for Cancer Therapy written by Piyush Kumar and published by Springer. This book was released on 2016-11-21 with total page 77 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Brief focuses on the cancer therapy available till date, from conventional drug delivery to nanomedicine in clinical trial. In addition, it reports on future generation based nanotherapeutics and cancer theranostic agent for effective therapeutic diagnosis and treatment. Breast cancer was chosen as the model system in this review. The authors give emphasis to multiple drug resistance (MDR) and its mechanism and how to overcome it using the nanoparticle approach.

Nanomedicine for Cancer Diagnosis and Therapy

Author : Arshi Malik
Publisher : Springer Nature
ISBN 13 : 9811575649
Total Pages : 249 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Nanomedicine for Cancer Diagnosis and Therapy by : Arshi Malik

Download or read book Nanomedicine for Cancer Diagnosis and Therapy written by Arshi Malik and published by Springer Nature. This book was released on 2021-08-01 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the current applications and future prospects of nanomaterials in cancer diagnostics and therapy. Nanomaterials have recently emerged as a remarkable and promising tool for cancer therapy and diagnosis, due to their broad range of intrinsic molecular properties. To overcome the current limitations of nanoparticles in drug delivery systems, attempts have been made to synthesize nanoparticles from biological materials for targeted cancer therapy. This book provides concise evaluations of various potential bio-inspired platforms that mimic natural components of the body and offer effective and versatile drug delivery systems for cancer therapy. It also assesses the potential of nanoparticles to enhance the outcomes of cancer immunotherapy via immune cell activation and tumor microenvironment modulation. The book also summarizes in the applications of nanomaterials for the detection, prevention, and treatment of solid tumors and in the treatment of leukemia and lymphomas. In closing, it discusses ethical issues in nanomedicine, including risk assessment, risk management, and risk communication during clinical trials. The book offers offers a valuable source of information for students, academics, researchers, scientists, clinicians, and healthcare professionals working in nanotechnology and cancer research.