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Author : Wilfred Gordon Bigelow
Publisher :
ISBN 13 : 9780075510048
Total Pages : 205 pages
Book Rating : 4.5/5 (1 download)
Download or read book Mysterious Heparin written by Wilfred Gordon Bigelow and published by . This book was released on 1990 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Shelley McKellar
Publisher : University of Toronto Press
ISBN 13 : 9780802037398
Total Pages : 366 pages
Book Rating : 4.0/5 (373 download)
Download or read book Surgical Limits written by Shelley McKellar and published by University of Toronto Press. This book was released on 2003-01-01 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: A biography of the life of Gordon Murray.
Author : Hari G. Garg
Publisher : Elsevier
ISBN 13 : 0080529054
Total Pages : 793 pages
Book Rating : 4.0/5 (85 download)
Download or read book Chemistry and Biology of Heparin and Heparan Sulfate written by Hari G. Garg and published by Elsevier. This book was released on 2011-10-10 with total page 793 pages. Available in PDF, EPUB and Kindle. Book excerpt: The chemistry, biochemistry and pharmacology of heparin and heparan sulfate have been and continue to be a major scientific undertaking - heparin and its derivative remain important drugs in clinical practice. Chemistry and Biology of Heparin and Heparan Sulfate provides readers with an insight into the chemistry, biology and clinical applications of heparin and heparan sulfate and examines their function in various physiological and pathological conditions. Providing a wealth of useful information, no other tome covers the diversity of topics in the field. Students, doctors, chemists, biochemists, and research scientists will find this book an invaluable source for updating their current knowledge of developments in this area. - Comprehensively reviews all aspects of heparin and heparan sulfate research - Uniquely describes the chemistry, biology and clinical application of heparins and heparan sulfates in one work - Provides an invaluable source of knowledge of current developments for chemists, biochemists, medical doctors, researchers, students and practitioners
Author : David Green
Publisher : Academic Press
ISBN 13 : 9780128187814
Total Pages : 200 pages
Book Rating : 4.1/5 (878 download)
Download or read book The Heparins written by David Green and published by Academic Press. This book was released on 2020-03 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than 30 tons of the anticoagulant, heparin, are produced annually, making it one of the most widely used drugs worldwide. It is a major pharmaceutical whose properties and clinical applications continue to be investigated and examined. The Heparins-Unfractionated, Low Molecular Weight, and Non-Anticoagulant describes the fascinating history of the discovery of this biological agent, how it was isolated and characterized, and its use for the treatment of thrombotic disorders. The structures of the various heparins are illustrated, and their function as anticoagulants delineated. Dr. Green is an internationally known hematologist with 45 years of clinical and research experience and an expert on bleeding and clotting disorders. This resource arms researchers and clinicians with a concise and practical source of information about the heparins, assisting biomedical research and medical practice and ultimately improving patient outcomes. Provides a clinical perspective on the properties of the heparins, their indications and adverse effects, and the new products in development Describes new pharmaceuticals derived from heparin that are devoid of anticoagulant activity but retain anti-inflammatory and anti-proliferative properties Discusses development of non-anticoagulant heparins for the treatment of diseases ranging from asthma to cancer Describes the history of the discovery of this biological agent, how it was isolated and characterized, and its use for the treatment of thrombotic disorders
Author : Rebecca Lever
Publisher : Springer
ISBN 13 : 9783642434587
Total Pages : 0 pages
Book Rating : 4.4/5 (345 download)
Download or read book Heparin - A Century of Progress written by Rebecca Lever and published by Springer. This book was released on 2014-06-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heparins remain amongst the most commonly used drugs in clinical practice. Almost 100 years have passed since the initial discovery of this complex substance and, during this time, understanding of the nature and uses of heparin and related molecules has grown dramatically. The aim of this volume is to summarise the developments that have led to the current status of both heparins as drugs and the field of heparin research, with a focus on the particularly rapid progress that has been made over the past three decades. Individual sections are dedicated to the nature of heparin as a biological molecule, the current approaches and techniques that are used to ensure the safety and reliability of heparin as a medicine, the clinical pharmacology of heparin as an anticoagulant drug, effects and potential applications of heparin aside of those involving haemostasis and, finally, the nature and potential uses of heparin-like materials from both natural and synthetic sources.
Author : Ralph Bradshaw
Publisher : Springer
ISBN 13 : 9781468409482
Total Pages : 423 pages
Book Rating : 4.4/5 (94 download)
Download or read book Heparin written by Ralph Bradshaw and published by Springer. This book was released on 2012-08-31 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Symposium on Heparin, held May 13-15, 1974, in St. Louis, Missouri, as a part of the dedication of the Shoenberg Pavilion of the Jewish Hospital of St. Louis, was conceived as a forum to bring together physicians and scientists with a basic in terest in the structure, function and clinical usefulness of heparin. Few naturally occurring substances have commanded the breadth of interest among members of the biomedical research community as this compound has. Aspects of its covalent and three-dimensional struc ture, its biosynthesis, its interaction with and effect on physio logically important moieties and its use as a therapeutic agent in a variety of disease states have been actively studied for the past several decades. Thus, the present state of these studies seemed to be a timely subject for discussion, not only to gather together in one place representative samples of the myriad of data on heparin but also to underscore the ever increasing necessity for communica tion between basic research and clinical practice.
Author : Edward Shorter
Publisher : University of Toronto Press
ISBN 13 : 1442645954
Total Pages : 993 pages
Book Rating : 4.4/5 (426 download)
Download or read book Partnership for Excellence written by Edward Shorter and published by University of Toronto Press. This book was released on 2013-01-01 with total page 993 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Partnership for Excellence, senior medical historian and award-winning author Edward Shorter details the Faculty of Medicine's history from its inception as a small provincial school to its present day status as an international powerhouse.
Author : National Library of Medicine (U.S.)
Publisher :
ISBN 13 :
Total Pages : 508 pages
Book Rating : 4.3/5 (91 download)
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Author : Ralph Bradshaw
Publisher :
ISBN 13 : 9781468409475
Total Pages : 436 pages
Book Rating : 4.4/5 (94 download)
Download or read book Heparin written by Ralph Bradshaw and published by . This book was released on 2014-01-15 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Daniel A. Goor
Publisher : Vantage Press, Inc
ISBN 13 : 9780533155576
Total Pages : 444 pages
Book Rating : 4.1/5 (555 download)
Download or read book The Genius of C. Walton Lillehei and the True History of Open Heart Surgery written by Daniel A. Goor and published by Vantage Press, Inc. This book was released on 2007 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: A brilliant heart surgeon whose discoveries paved the way for generations of other doctors in his field has his career and reputation torn apart. Armed with fresh and thoroughly researched information on one of the most influential - and enigmatic- figures in medicine, Goor's fascinating, insightful biography combines an understanding of both science and the politics involved in the history of the repair and healing of the human heart.
Author : J.T.H. Connor
Publisher : University of Toronto Press
ISBN 13 : 1442658029
Total Pages : 398 pages
Book Rating : 4.4/5 (426 download)
Download or read book Doing Good written by J.T.H. Connor and published by University of Toronto Press. This book was released on 2000-12-15 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: A history of Toronto’s general hospital offers a window on a broader history of Upper Canada and Ontario over the last two centuries. In this lively and authoritative account, J.T.H. Connor traces the hospital’s two-hundred-year evolution, as its mandate to ‘do good’ forced constant adjustment to changing social, medical, and government attitudes. Doing Good presents the hospital’s history in three phases – roughly speaking, the first and second halves of the nineteenth century, and the twentieth century. From its conception in 1797 to the mid-1850s – it did not actually acquire a home until 1819 nor occupy it until 1829 – it functioned as a charitable institution, catering to the sick poor. It acted initially as a clearing station for sick immigrants; it later was deeply affected by political events and became embroiled in the medical turmoil of Toronto in the 1840s and early 1850s. In the second era, from the mid-1850s, it was a public charity, receiving stable government funding and constructing a new home in eastern Toronto. By the 1870s, it was winning praise as a model hospital. In the twentieth century, it early on established close links with the University of Toronto, building a vast and up-to-date new facility adjacent to the university, which opened in 1913. Its international reputation as an academic hospital grew over the decades to include a high profile in research, most notably in cancer and medical technology. By the 1960s the institution was being run as a public hospital, and the late 1990s saw its absorption into a hospital mega-corporation – the University Health Network – along with three other nearby hospitals. This work is the most comprehensive analysis of any Canadian hospital or health care institution yet to appear. Using trustees’ minutes, medical journals, newspapers, and government reports, along with correspondence, photographs, and reminiscences of trustees, nurses, doctors, and patients, Connor offers acute observation and detailed analysis, as well as compelling character studies and revealing anecdotes. Broad in scope and meticulously executed, Doing Good brings vividly to life the day-to-day routines, the behind-the-scenes intrigue, and the people and politics of a great urban hospital.
![Download Heparin : Structure, Function, and Clinical Implications : [Proceedings] PDF Online Free](https://books.google.com/books/content/images/frontcover/HK6TwgEACAAJ?fife=w200-h370)
Author : International Symposium on Heparin, St. Louis, 1974
Publisher :
ISBN 13 :
Total Pages : 422 pages
Book Rating : 4.:/5 (1 download)
Download or read book Heparin : Structure, Function, and Clinical Implications : [Proceedings] written by International Symposium on Heparin, St. Louis, 1974 and published by . This book was released on 1975 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Michael R. Buchanan
Publisher : CRC Press
ISBN 13 : 9780849376498
Total Pages : 238 pages
Book Rating : 4.3/5 (764 download)
Download or read book ThrombinIts Key Role in Thrombogenesis-Implications for Its Inhibition written by Michael R. Buchanan and published by CRC Press. This book was released on 1994-10-03 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new multi-authored book reviews the current understanding of the role of thrombin in venous and arterial thrombosis and its inhibition in the clinical setting. Heparin, the most widely used antithrombotic, does not effectively regulate thrombin or its formation. Accumulating evidence suggests that other antithrombins are effective in some of the situations where heparin is not. Discussions include the current knowledge on antithrombotic prophylaxis and therapy, from the perspective of the role in thrombin in venous and arterial vascular disease, the limitations of the current anticoagulant therapies, and potential and limitations of newer antithrombins currently being tested in several experimental and clinical settings. Thrombin helps the clinician to better rationalize the use of specific antithrombins in the prevention and management of thrombotic disease and provides the basic scientist with a better understanding of the goals the clinician attempts to achieve with antithrombotic therapy.
Author : Henry B.M. Best
Publisher : Dundurn
ISBN 13 : 155002986X
Total Pages : 564 pages
Book Rating : 4.5/5 (5 download)
Download or read book Margaret and Charley written by Henry B.M. Best and published by Dundurn. This book was released on 2003-06-01 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although Charles Best is known for discovering insulin, the story of his life neither begins nor ends with that one moment. Not only did he make many other discoveries, he was also one half of an extraordinary couple who, during their almost sixty years together, were involved in many of the significant events of the twentieth century. Margaret & Charley is the story of these two people from their beginnings on the east coast at the turn of the century through the years that followed. Through diaries, scrapbooks, photograph albums, and other documentation, the details of their lives are shared with the reader.
Author : P. Van Schil
Publisher : Nova Publishers
ISBN 13 : 9781594544507
Total Pages : 254 pages
Book Rating : 4.5/5 (445 download)
Download or read book Lung Metastases and Isolated Lung Perfusion written by P. Van Schil and published by Nova Publishers. This book was released on 2007 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surgical resection of lung metastases is a widely accepted procedure but long-term results are disappointing with a 5-year survival rate of approximately 40%. The main prognostic factor is complete resection and a better survival is reported in patients with a single metastasis and a disease-free survival of more than 3 years. Re-operations are feasible but often patients become inoperable due to insufficient pulmonary reserve and new treatment modalities are looked for. Intravenous (iv) chemotherapy has no major impact on survival due to systemic side-effects when high doses are given. As isolated limb and liver perfusion, isolated lung perfusion (ILuP) has the advantage of selectively delivering an agent into the lung while diverting the venous effluent. This allows the drug to be given in a significantly higher dose compared to iv therapy, while drug levels in the other organs are kept low enough to avoid major complications. ILuP has been shown to be very effective for the treatment of lung metastases in animal models. Phase I clinical studies to determine dose-limiting toxicity and maximum tolerated dose have recently been reported. The principal aim of this book is to discuss the current treatment of lung metastases and the possible contribution of ILuP.
Author : Bruce Fye
Publisher : Oxford University Press, USA
ISBN 13 : 019998235X
Total Pages : 705 pages
Book Rating : 4.1/5 (999 download)
Download or read book Caring for the Heart written by Bruce Fye and published by Oxford University Press, USA. This book was released on 2015 with total page 705 pages. Available in PDF, EPUB and Kindle. Book excerpt: This study explores the parallel histories of the Mayo Clinic, the care of patients with heart disease, and specialization in cardiology during the twentieth century. Chapters are devoted to such technologies as open-heart surgery, coronary angiography, and echocardiography, and to the key individuals, instituions, and innovations that played vital roles in the technologies that transformed heart care.--From publisher description.
Author : G. Wayne Miller
Publisher : Crown
ISBN 13 : 0307557243
Total Pages : 320 pages
Book Rating : 4.3/5 (75 download)
Download or read book King of Hearts written by G. Wayne Miller and published by Crown. This book was released on 2010-02-10 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Few of the great stories of medicine are as palpably dramatic as the invention of open-heart surgery, yet, until now, no journalist has ever brought all of the thrilling specifics of this triumph to life. This is the story of the surgeon many call the father of open-heart surgery, Dr. C. Walton Lillehei, who, along with colleagues at University Hospital in Minneapolis and a small band of pioneers elsewhere, accomplished what many experts considered to be an impossible feat: He opened the heart, repaired fatal defects, and made the miraculous routine. Acclaimed author G. Wayne Miller draws on archival research and exclusive interviews with Lillehei and legendary pioneers such as Michael DeBakey and Christiaan Barnard, taking readers into the lives of these doctors and their patients as they progress toward their landmark achievement. In the tradition of works by Richard Rhodes and Tracy Kidder, King of Hearts tells the story of an important and gripping piece of forgotten science history.
