Myocardial Protection and the KATP Channel

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Publisher : Springer Science & Business Media
ISBN 13 : 9780792337911
Total Pages : 232 pages
Book Rating : 4.3/5 (379 download)

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Book Synopsis Myocardial Protection and the KATP Channel by : Derek Yellon

Download or read book Myocardial Protection and the KATP Channel written by Derek Yellon and published by Springer Science & Business Media. This book was released on 1995-12-31 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ATP-sensitive potassium channel (KATP) was discovered in 1983. Since then, an enormous amount of research has been undertaken to characterize it in detail. This volume consolidates both the current knowledge and most recent advances on the subject, and its relationship to myocardial protection. To this end, the editors have assembled investigators at the forefront of ongoing basic and clinical research to provide scholarly and candid comments concerning each of the pertinent issues, including: a comprehensive review of the biology of the channel with respect to the structure-activity relationship as well as overall chemistry of the channel; the role of opening this channel and its effect on smooth muscle (covering both the effects on myocardial stunning and its ability to protect against myocardial infarction); the relationship of KATP channel opening and the protection to the myocardium afforded by the phenomenon of ischemic preconditioning; the relationship between the KATP channel and electrophysiological consequences with specific reference to arrhythmogenicity; and the clinical implications of the use of agents that mimic the opening of this channel, with reference to its protective nature and its use in the treatment of angina. Audience: Clinicians and basic scientists who have a direct interest in the KATP channel as well as those groups who are interested in the entire concept of myocardial protection and its relationship to academic and clinical medicine.

The Use and Efficacy of a Katp Channel Opener for Myocardial Protection in Cardiac Surgery and Heart Transplantation

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Publisher :
ISBN 13 :
Total Pages : 596 pages
Book Rating : 4.:/5 (222 download)

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Book Synopsis The Use and Efficacy of a Katp Channel Opener for Myocardial Protection in Cardiac Surgery and Heart Transplantation by : Omal V. Walgama

Download or read book The Use and Efficacy of a Katp Channel Opener for Myocardial Protection in Cardiac Surgery and Heart Transplantation written by Omal V. Walgama and published by . This book was released on 2005 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Use and Efficacy of a KATP Channel Opener for Myocardial Protection in Cardiac Surgery and Transplantation

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Publisher :
ISBN 13 :
Total Pages : 596 pages
Book Rating : 4.:/5 (5 download)

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Book Synopsis The Use and Efficacy of a KATP Channel Opener for Myocardial Protection in Cardiac Surgery and Transplantation by :

Download or read book The Use and Efficacy of a KATP Channel Opener for Myocardial Protection in Cardiac Surgery and Transplantation written by and published by . This book was released on 2005 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Purines and Myocardial Protection

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Publisher : Springer Science & Business Media
ISBN 13 : 9780792338314
Total Pages : 596 pages
Book Rating : 4.3/5 (383 download)

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Book Synopsis Purines and Myocardial Protection by : Anwar-Saad A. Abd-Elfattah

Download or read book Purines and Myocardial Protection written by Anwar-Saad A. Abd-Elfattah and published by Springer Science & Business Media. This book was released on 1996-01-31 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: A critical review of the most up-to-date research on purines and myocardial protection. The role of purines in reversible `myocardial stunning' and irreversible (myocardial infarction) ischemic injury, ventricular arrhythmias, and ischemic preconditioning is discussed in detail, by experts. All reviews address recent and rather controversial issues on purines and myocardial protection. Mechanisms of cardioprotection of exogenous versus endogenous purines are discussed in detail. The contribution of internationally recognized experts in the field of purines and cardiovascular physiology and in myocardial protection makes this a unique and interesting book for clinicians, basic scientists and students.

Myocardial Protection

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1405178434
Total Pages : 344 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Myocardial Protection by : Tomas A. Salerno

Download or read book Myocardial Protection written by Tomas A. Salerno and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myocardial protection is regarded as one of the most important, yet also most controversial aspects of cardiac surgery. There has been considerable improvement in myocardial protection strategies over recent years, utilising a variety of new approaches to treat cardiac diseases, and this text is intended to embrace the state of the art in this field. The book summarises the state of knowledge on all aspects of myocardial protection, including the latest in the treatment of cardiac diseases, robotics, pediatric surgery and the treatment of cardiac failure. Robotic surgery, valvular surgery, pediatric surgery and coronary surgery are all covered by renowned experts, producing a comprehensive, forward-looking view of the field of myocardial protection. This book should function to update physicians and surgeons interested in the field of cardiac surgery on the current state of knowledge on myocardial protection.

Myocardial Protection

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Author :
Publisher : Wiley-Blackwell
ISBN 13 : 1405178434
Total Pages : 344 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Myocardial Protection by : Tomas A. Salerno

Download or read book Myocardial Protection written by Tomas A. Salerno and published by Wiley-Blackwell. This book was released on 2008-04-15 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myocardial protection is regarded as one of the most important, yet also most controversial aspects of cardiac surgery. There has been considerable improvement in myocardial protection strategies over recent years, utilising a variety of new approaches to treat cardiac diseases, and this text is intended to embrace the state of the art in this field. The book summarises the state of knowledge on all aspects of myocardial protection, including the latest in the treatment of cardiac diseases, robotics, pediatric surgery and the treatment of cardiac failure. Robotic surgery, valvular surgery, pediatric surgery and coronary surgery are all covered by renowned experts, producing a comprehensive, forward-looking view of the field of myocardial protection. This book should function to update physicians and surgeons interested in the field of cardiac surgery on the current state of knowledge on myocardial protection.

Myocardial Preservation and Cellular Adaptation

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Publisher : Elsevier
ISBN 13 : 0080877230
Total Pages : 297 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Myocardial Preservation and Cellular Adaptation by : D.K. Das

Download or read book Myocardial Preservation and Cellular Adaptation written by D.K. Das and published by Elsevier. This book was released on 1998-12-18 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Living organisms exhibit specific responses when confronted with sudden changes in their environmental conditions. The ability of the cells to acclimate to their new environment is the integral driving force for adaptive modification of the cells. Such adaptation involves a number of cellular and biochemical alteration including metabolic homeostasis and reprogramming of gene expression. Changes in metabolic pathways are generally short-lived and reversible, while the consequences of gene expression are a long-term process and may lead to permanent alternation in the pattern of adaptive responses. The heart possesses remarkable ability to adapt itself against any stressful situation by increasing resistance to the adverse consequences. Stress composes the foundation of many degenerative heart diseases including atherosclerosis, spasm, thrombosis, cardiomyopathy, and congestive heart failure. Based on the concept that excessive stress may play a crucial role in the pathogenesis of ischemic heart disease, attempts were made to design methods for preventing of myocardial injury. Creation of stress reactions by repeated ischemia and reperfusion or subjecting the hearts to heat or oxidative stress enables them to meet the future stress challenge. Repeated stress exposures adapt the heart to withstand more severe stress reactions probably by upregulating the cellular defense and direct accumulation of intracellular mediators, which presumably constitute the material basis of increased adaptation to stress. Thus, the powerful cardioprotective effect of adaptation is likely to originate at the cellular and molecular levels that compose fundamental processes in the prophylaxis of such diseases. Volume six of the Advances in Organ Biology series contains state-of-the-art reviews on myocardial preservation and cellular adaptation from the leading authorities in this subject.

The Involvement of ATP-sensitive Potassium Channels in Novel Forms of Myocardial Protection

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (595 download)

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Book Synopsis The Involvement of ATP-sensitive Potassium Channels in Novel Forms of Myocardial Protection by : Theresa Jane Pell

Download or read book The Involvement of ATP-sensitive Potassium Channels in Novel Forms of Myocardial Protection written by Theresa Jane Pell and published by . This book was released on 1999 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Myocardial Preconditioning

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Publisher : Springer Science & Business Media
ISBN 13 : 366222206X
Total Pages : 296 pages
Book Rating : 4.6/5 (622 download)

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Book Synopsis Myocardial Preconditioning by : Cherry L. Wainwright

Download or read book Myocardial Preconditioning written by Cherry L. Wainwright and published by Springer Science & Business Media. This book was released on 2013-11-22 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about the unique ability of the heart to protect itself against the serious consequences of an abrupt reduction in blood flow to the myocardium - a phenomenon which is switched on by stress and termed myocardial preconditioning. This volume describes the main features and characteristics of preconditioning, with respect to the time-course of the protective effect of the phenomenon (first and second windows) and the different sequelae of myocardial ischaemia against which it protects, such as myocardial injury, arrhythmias and contractile dysfunction. The proposed mechanisms underlying the fascinating form of cardioprotection are discussed. Among these are the role of endogenous labile mediators, receptor-linked G proteins, ATP-sensitive potassium channels and protein kinase C activation.

Pharmacological Approaches to Cardioprotection

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Publisher :
ISBN 13 :
Total Pages : 508 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Pharmacological Approaches to Cardioprotection by : James Allen Coles

Download or read book Pharmacological Approaches to Cardioprotection written by James Allen Coles and published by . This book was released on 2002 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Electrical Diseases of the Heart

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Publisher : Springer Science & Business Media
ISBN 13 : 1447148819
Total Pages : 661 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Electrical Diseases of the Heart by : Ihor Gussak

Download or read book Electrical Diseases of the Heart written by Ihor Gussak and published by Springer Science & Business Media. This book was released on 2013-04-22 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: Electrical Disease of the Heart, 2nd Edition, volume 1, provides a valuable insight to the latest developments in the field of cardiac electrophysiology and clinical electrocardiology. Each chapter includes up-to-date results of studies aimed at providing an understanding of the electrical function of the heart in health and disease, established and evidence-based knowledge of clinical outcomes, areas of controversy, and future trends. This book is highly relevant to a broad audience, ranging from medical and graduate students, to clinicians and scientists.

Pharmacological Preconditioning with Opioids for Myocardial Protection

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Author :
Publisher :
ISBN 13 :
Total Pages : 526 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Pharmacological Preconditioning with Opioids for Myocardial Protection by : Daniel Conrad Sigg

Download or read book Pharmacological Preconditioning with Opioids for Myocardial Protection written by Daniel Conrad Sigg and published by . This book was released on 2001 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cardioprotection

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Author :
Publisher : Oxford University Press
ISBN 13 : 019954476X
Total Pages : 138 pages
Book Rating : 4.1/5 (995 download)

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Book Synopsis Cardioprotection by : Derek Hausenloy

Download or read book Cardioprotection written by Derek Hausenloy and published by Oxford University Press. This book was released on 2009-08-20 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coronary heart disease (CHD) is the leading cause of death worldwide. Cardioprotection refers to the prevention of CHD and the clinical improvement in patients suffering from cardiovascular problems.

Purines and Myocardial Protection

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461304555
Total Pages : 565 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Purines and Myocardial Protection by : Anwar-Saad A. Abd-Elfattah

Download or read book Purines and Myocardial Protection written by Anwar-Saad A. Abd-Elfattah and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: A critical review of the most up-to-date research on purines and myocardial protection. The role of purines in reversible `myocardial stunning' and irreversible (myocardial infarction) ischemic injury, ventricular arrhythmias, and ischemic preconditioning is discussed in detail, by experts. All reviews address recent and rather controversial issues on purines and myocardial protection. Mechanisms of cardioprotection of exogenous versus endogenous purines are discussed in detail. The contribution of internationally recognized experts in the field of purines and cardiovascular physiology and in myocardial protection makes this a unique and interesting book for clinicians, basic scientists and students.

Cardiopulmonary Bypass

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Author :
Publisher : Cambridge University Press
ISBN 13 : 1107428254
Total Pages : 271 pages
Book Rating : 4.1/5 (74 download)

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Book Synopsis Cardiopulmonary Bypass by : Sunit Ghosh

Download or read book Cardiopulmonary Bypass written by Sunit Ghosh and published by Cambridge University Press. This book was released on 2015-11-26 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete clinically orientated guide to cardiopulmonary bypass and extracorporeal support for trainee medical and technical personnel in cardiac surgery.

Handbook of Cardiac Anatomy, Physiology, and Devices

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Author :
Publisher : Springer
ISBN 13 : 331919464X
Total Pages : 806 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Handbook of Cardiac Anatomy, Physiology, and Devices by : Paul A. Iaizzo

Download or read book Handbook of Cardiac Anatomy, Physiology, and Devices written by Paul A. Iaizzo and published by Springer. This book was released on 2015-11-13 with total page 806 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the latest information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Key chapters address animal models for cardiac research, cardiac mapping systems, heart-valve disease and genomics-based tools and technology. Once again, a companion of supplementary videos offer unique insights into the working heart that enhance the understanding of key points within the text. Comprehensive and state-of-the art, the Handbook of Cardiac Anatomy, Physiology and Devices, Third Edition provides clinicians and biomedical engineers alike with the authoritative information and background they need to work on and implement tomorrow’s generation of life-saving cardiac devices.

Heat Shock Proteins in Myocardial Protection

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Author :
Publisher : CRC Press
ISBN 13 : 1498712665
Total Pages : 145 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Heat Shock Proteins in Myocardial Protection by : Rakesh C. Kukreja

Download or read book Heat Shock Proteins in Myocardial Protection written by Rakesh C. Kukreja and published by CRC Press. This book was released on 2000-08-01 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myocardial ischemic syndromes pose a major medical problem and a significant economic health care concern. Reperfusion, although used in the clinical arena as essential to the survival of acutely ischemic heart muscle carries with it the risk of reperfusion injury. Therefore the salvage of additional myocardium is highly desirable.