Myeloproliferative Neoplasms An Issue Of Hematology Oncology Clinics Of North America Volume 35 2

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Myeloproliferative Neoplasms, an Issue of Hematology/Oncology Clinics of North America, Volume 35-2

Author : John Mascarenhas
Publisher : Elsevier
ISBN 13 : 9780323795883
Total Pages : 240 pages
Book Rating : 4.7/5 (958 download)

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Book Synopsis Myeloproliferative Neoplasms, an Issue of Hematology/Oncology Clinics of North America, Volume 35-2 by : John Mascarenhas

Download or read book Myeloproliferative Neoplasms, an Issue of Hematology/Oncology Clinics of North America, Volume 35-2 written by John Mascarenhas and published by Elsevier. This book was released on 2021-04-28 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Hematology/Oncology Clinics, guest edited by Drs. Ronald Hoffman, Ross Levine, John Mascarenhas, and Raajit Rampal, is dedicated to Myeloproliferative Neoplasms. This issue is one of six selected each year by the series consulting editors, Drs. George P. Canellos and Edward J. Benz. Topics in this issue include-but are not limited to- Overview of pathophysiology and potential drug targets, The role of the megakaryocyte, Epigenetics, Genetics, Novel technologies for understanding MPN biology, Important pathology considerations, Current Clinical investigations, Quality of life, Application of stem cell therapy, Immunotherapy approaches, Clinical unmet needs in ET/PV, Accelerated and blast phase MPNs, Epidemiology, Thrombotic and hemorrhagic complications, Murine modeling, The microenvironment in MPNs, MDS/MPN overlap syndrome, and Advancing effective clinical trial designs.

Myeloproliferative Neoplasms, An Issue of Hematology/Oncology Clinics of North America

Author : John Mascarenhas
Publisher : Elsevier Health Sciences
ISBN 13 : 0323795897
Total Pages : 240 pages
Book Rating : 4.3/5 (237 download)

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Book Synopsis Myeloproliferative Neoplasms, An Issue of Hematology/Oncology Clinics of North America by : John Mascarenhas

Download or read book Myeloproliferative Neoplasms, An Issue of Hematology/Oncology Clinics of North America written by John Mascarenhas and published by Elsevier Health Sciences. This book was released on 2021-02-27 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Hematology/Oncology Clinics, guest edited by Drs. Ronald Hoffman, Ross Levine, John Mascarenhas, and Raajit Rampal, is dedicated to Myeloproliferative Neoplasms. This issue is one of six selected each year by the series consulting editors, Drs. George P. Canellos and Edward J. Benz. Topics in this issue include—but are not limited to— Overview of pathophysiology and potential drug targets, The role of the megakaryocyte, Epigenetics, Genetics, Novel technologies for understanding MPN biology, Important pathology considerations, Current Clinical investigations, Quality of life, Application of stem cell therapy, Immunotherapy approaches, Clinical unmet needs in ET/PV, Accelerated and blast phase MPNs, Epidemiology, Thrombotic and hemorrhagic complications, Murine modeling, The microenvironment in MPNs, MDS/MPN overlap syndrome, and Advancing effective clinical trial designs.

Non-CML Myeloproliferative Diseases, An Issue of Hematology/Oncology Clinics of North America

Author : Ross Levine
Publisher : Elsevier Health Sciences
ISBN 13 : 1455747645
Total Pages : 193 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Non-CML Myeloproliferative Diseases, An Issue of Hematology/Oncology Clinics of North America by : Ross Levine

Download or read book Non-CML Myeloproliferative Diseases, An Issue of Hematology/Oncology Clinics of North America written by Ross Levine and published by Elsevier Health Sciences. This book was released on 2012-10-28 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topics include: Clinical Predictors of Outcome in MPNs; Molecular pathogenesis of MPNs; Disordered signaling in MPNs; Role of TET2/ASXL1 in MPN Pathogenesis; Pathogenesis and treatment of systemic mastocytosis; Role of additional novel therapies in MPNs; Role of novel mutations in MPN pathogenesis and outcome; Role of JAK inhibitors in MPN treatment; Animal Models of MPNs; and Role of Germline Genetic Factors in MPN Pathogenesis.

Consultative Hematology, An Issue of Hematology/Oncology Clinics of North America

Author : Fred J. Schiffman
Publisher : Elsevier Health Sciences
ISBN 13 : 1455744077
Total Pages : 256 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Consultative Hematology, An Issue of Hematology/Oncology Clinics of North America by : Fred J. Schiffman

Download or read book Consultative Hematology, An Issue of Hematology/Oncology Clinics of North America written by Fred J. Schiffman and published by Elsevier Health Sciences. This book was released on 2012-04-28 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topics include: Why does my patient have leukocytosis?, Why Is My Patient Neutropenic?, Does My Patient with a Serum Monoclonal Spike have Multiple Myeloma?, DVT and Pulmonary Embolism, Why Does My Patient Have Lymphadenopathy/Splenomegaly?,and Why Does My Patient have Thrombocytopenia?

Bone Marrow Transplantation, An Issue of Hematology/Oncology Clinics of North America

Author : Bipin Savani
Publisher : Elsevier Health Sciences
ISBN 13 : 0323354599
Total Pages : 217 pages
Book Rating : 4.3/5 (233 download)

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Book Synopsis Bone Marrow Transplantation, An Issue of Hematology/Oncology Clinics of North America by : Bipin Savani

Download or read book Bone Marrow Transplantation, An Issue of Hematology/Oncology Clinics of North America written by Bipin Savani and published by Elsevier Health Sciences. This book was released on 2016-03-25 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Hematology/Oncology Clinics of North America, guest edited by Drs. Bipin Savani and Mohamad Mohty, is devoted to Bone Marrow Transplantation. Articles in this issue include: Acute Myeloid Leukemia (AML); Acute Lymphoid Leukemia (ALL); Myelodysplastic Syndrome (AML); Myeloproliferative disorders (MPD); Chronic Lymphoid Leukemia; Chronic Myeloid Leukemia (CML); Multiple Myeloma and Amyloidosis; Non-Hodgkin Lymphoma (NHL); Hodgkin Lymphoma (HL); Severe Aplastic Anemia (SAA) and Paroxysmal Nocturnal Hemoglobinuria (PNH); Sickle Cell Anemia; Thalassemia; Benign immunodeficiency diseases; and Referral to transplant centers.

Hematology/Oncology Emergencies, An Issue of Hematology/Oncology Clinics of North America

Author : John C. Perkins
Publisher : Elsevier Health Sciences
ISBN 13 : 0323611486
Total Pages : pages
Book Rating : 4.3/5 (236 download)

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Book Synopsis Hematology/Oncology Emergencies, An Issue of Hematology/Oncology Clinics of North America by : John C. Perkins

Download or read book Hematology/Oncology Emergencies, An Issue of Hematology/Oncology Clinics of North America written by John C. Perkins and published by Elsevier Health Sciences. This book was released on 2017-11-06 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Hematology/Oncology Clinics, edited by Drs. John Perkins and and Jonathan Davis, focuses on emergencies related to Hematology/Oncology and covers topics such as: Oncologic Mechanical Emergencies, Neutropenic Fever, Oncologic Metabolic Emergencies, Acute Leukemias, Pediatric Oncologic Emergencies, Chemotherapeutic Medications and their Emergent Complications, Anemia, Thrombotic Microangiopathies (TTP, HUS, HELLP), Congenital Bleeding Disorders, Acquired Bleeding Disorders and Antithrombotic agents, Sickle Cell Disease, and more!

Atlas of Diagnostic Hematology

Author : Mohamed E. Salama
Publisher : Elsevier Health Sciences
ISBN 13 : 0323567347
Total Pages : 415 pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis Atlas of Diagnostic Hematology by : Mohamed E. Salama

Download or read book Atlas of Diagnostic Hematology written by Mohamed E. Salama and published by Elsevier Health Sciences. This book was released on 2020-09-01 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ideal as a quick, easy-to-use reference in the laboratory or clinical setting, Atlas of Diagnostic Hematology is an abundantly illustrated guide to the vast range of malignant and non-malignant disorders of the blood. More than 1,200 vibrant, full-color images enable you to identify and compare the unique clinical and histologic features of various blood disorders and confidently reach a diagnosis. Coverage includes photos of actual cases that span the entire range of this complex field, including rare conditions and difficult diagnoses. Features more than 1,200 images including full-color pathologic and clinical images covering a wide range of hematologic malignant and non-malignant conditions. Covers a range of disease stages, from the slightest indication where diagnosis can be complicated or missed entirely, to what the average blood or biopsy sample signifying disease may look like, to an advanced stage where disease indications are abundantly clear. Helps you distinguish between similar and overlapping features and symptoms to arrive at an accurate diagnosis. Provides up-to-date information on infectious processes in blood and bone marrow, classification system of myeloid neoplasms, and indolent and aggressive mature T and NK-cell lymphomas. Includes diagnostic algorithms with differential diagnoses for conditions with similar histologic features and clinical symptoms. Contains the latest WHO classifications for pathologic, genetic, and clinical information.

How to Talk with Your Doctor

Author : Ronald L Hoffman, M D
Publisher : ReadHowYouWant.com
ISBN 13 : 1458701328
Total Pages : 570 pages
Book Rating : 4.4/5 (587 download)

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Book Synopsis How to Talk with Your Doctor by : Ronald L Hoffman, M D

Download or read book How to Talk with Your Doctor written by Ronald L Hoffman, M D and published by ReadHowYouWant.com. This book was released on 2009-05-15 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now more than ever patients are taking control of their own health care, leaving many conventional physicians unsure about their role as dispensers of medical knowledge. More waiting rooms are now filled with highly informed medical consumers seeking to partner with their doctors. They want to explore all promising treatments, both mainstream and alternative, and connect emotionally. To physicians, these patients seem needy and demanding. They expect a lot of attention, but are all too quick to question authority and battle doctors for control of medical care. To patients, though, such physicians come off as distant and stodgy, even arrogant. Many walk away entirely from mainstream medicine seeking a better partnership or they neglect to mention the alternative treatments they're using for fear of disapproval. Less assertive patients simply clam up-put off by doctors' increasingly brusque bedside manner and shorthand use of ''medicalese.'' The unfortunate result in each case is the same: miscommunication and missed opportunities. Patients fail to receive the best care available to them, and doctor-patient relationships fall far short of the caring and mutually satisfying exchanges they should be.

Mathematical Modeling and Computational Predictions in Oncoimmunology

Author : Vladimir A. Kuznetsov
Publisher : Frontiers Media SA
ISBN 13 : 2832550061
Total Pages : 121 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Mathematical Modeling and Computational Predictions in Oncoimmunology by : Vladimir A. Kuznetsov

Download or read book Mathematical Modeling and Computational Predictions in Oncoimmunology written by Vladimir A. Kuznetsov and published by Frontiers Media SA. This book was released on 2024-06-06 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is a complex adaptive dynamic system that causes both local and systemic failures in the patient. Cancer is caused by a number of gain-of-function and loss-of-function events, that lead to cells proliferating without control by the host organism over time. In cancer, the immune system modulates cancer cell population heterogeneity and plays a crucial role in disease outcomes. The immune system itself also generates multiple clones of different cell types, with some clones proliferating quickly and maturing into effector cells. By creating regulatory signals and their networks, and generating effector cells and molecules, the immune system recognizes and kills abnormal cells. Anti-cancer immune mechanisms are realized as multi-layer, nonlinear cellular and molecular interactions. A number of factors determine the outcome of immune system-tumor interactions, including cancer-associated antigens, immune cells, and host organisms.

Measuring the Invisible World

Author : Abraham Schierbeek
Publisher :
ISBN 13 :
Total Pages : 238 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Measuring the Invisible World by : Abraham Schierbeek

Download or read book Measuring the Invisible World written by Abraham Schierbeek and published by . This book was released on 1959 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers Leeuwenjoek's work in microbiology, histology, entomology, botany, and medicine.

Mayo Clinic Internal Medicine Board Review Questions and Answers

Author : Robert D. Ficalora
Publisher : Oxford University Press, USA
ISBN 13 : 0199985871
Total Pages : 164 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis Mayo Clinic Internal Medicine Board Review Questions and Answers by : Robert D. Ficalora

Download or read book Mayo Clinic Internal Medicine Board Review Questions and Answers written by Robert D. Ficalora and published by Oxford University Press, USA. This book was released on 2013-08-15 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Companion volume to: Mayo Clinic internal medicine board review. 10th ed. c2013.

Myeloproliferative Neoplasms

Author : Tiziano Barbui
Publisher : Springer Science & Business Media
ISBN 13 : 3642249884
Total Pages : 235 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Myeloproliferative Neoplasms by : Tiziano Barbui

Download or read book Myeloproliferative Neoplasms written by Tiziano Barbui and published by Springer Science & Business Media. This book was released on 2012-02-03 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on three of the main categories of myeloproliferative neoplasm: polycythemia vera, essential thrombocythemia, and primary myelofibrosis. Relevant laboratory and clinical advances are comprehensively covered, and great emphasis is placed on the practical issues that challenge physicians in their daily practice. The main topics considered thus include contemporary diagnostic approaches, the value and limitations of mutation screening for diagnostic and prognostic purposes, risk stratification in terms of both survival and other disease complications such as leukemic transformation and thrombosis, and modern therapeutic strategies, including conventional drugs, allogeneic stem cell transplantation, and experimental drugs still under study. The reader will find Critical Concepts and Management Recommendations in Myeloproliferative Neoplasms to be an invaluable and up-to-date source of information from leading authorities in the field.

Sunshine and Vitamin D

Author : Frank Murray
Publisher : Basic Health Publications, Inc.
ISBN 13 : 9781591202509
Total Pages : 244 pages
Book Rating : 4.2/5 (25 download)

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Book Synopsis Sunshine and Vitamin D by : Frank Murray

Download or read book Sunshine and Vitamin D written by Frank Murray and published by Basic Health Publications, Inc.. This book was released on 2008 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Foodborne pathogens enter the body through the intestinal tract where they cause temporary upsets. However, if they go from the intestinal tract into the bloodstream, they can invade other organs, systems, and structures, where they inflict damage such as some forms of heart disease, arthritis, and cancer. This book discusses the rising incidence of foodborne illness, and suggests ways in which the food regulators, and we, the consumers, can achieve a safer food supply.

Fast Facts: Myeloproliferative Neoplasms

Author : R.A. Mesa
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 1910797804
Total Pages : 117 pages
Book Rating : 4.9/5 (17 download)

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Book Synopsis Fast Facts: Myeloproliferative Neoplasms by : R.A. Mesa

Download or read book Fast Facts: Myeloproliferative Neoplasms written by R.A. Mesa and published by Karger Medical and Scientific Publishers. This book was released on 2019-02-11 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presentation of the myeloproliferative neoplasms (MPNs) varies widely, and correct diagnosis and management can be challenging, and is becoming more complex as understanding of the underlying molecular basis for these disorders emerges. Appropriate management is increasingly informed by accurate risk stratification founded on understanding of cytogenetic and molecular markers, as well as the clinical presentation. 'Fast Facts: myeloproliferative neoplasms' focuses on the three most common chronic MPNs: • Essential thrombocythemia (ET) – characterized by increased platelet count • Polycythemia vera (PV) – characterized by excessive production of red blood cells • Primary myelofibrosis – a more severe and heterogenous disorder that may overlap with ET and PV but is commonly associated with anemia. Written by two leading experts in the field, Fast Facts: myeloproliferative neoplasms provides concise, up-to-date and practical guidance on the accurate diagnosis, risk stratification and management of these MPNs. It also provides key insights into our growing understanding of the underlying molecular and genetic basis of these disorders, and how this is informing risk stratification and management strategies. This concise handbook will be invaluable to clinicians, medical students, nurses, pharmacists and scientists in understanding and overcoming the everyday and rarer challenges associated with MPN.

Consultative Hemostasis and Thrombosis E-Book

Author : Craig S. Kitchens
Publisher : Elsevier Health Sciences
ISBN 13 : 1455733296
Total Pages : 843 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Consultative Hemostasis and Thrombosis E-Book by : Craig S. Kitchens

Download or read book Consultative Hemostasis and Thrombosis E-Book written by Craig S. Kitchens and published by Elsevier Health Sciences. This book was released on 2013-02-20 with total page 843 pages. Available in PDF, EPUB and Kindle. Book excerpt: A unique clinical focus makes Consultative Hemostasis and Thrombosis, 3rd Edition your go-to guide for quick, practical answers on managing the full range of bleeding and clotting disorders. Emphasizing real-world problems and solutions, Dr. Craig S. Kitchens, Dr. Barbara A. Konkle, and Dr. Craig M. Kessler provide all the clinical guidance you need to make optimal decisions on behalf of your patients and promote the best possible outcomes. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Efficiently look up concise descriptions of each condition, its associated symptoms, laboratory findings, diagnosis, differential diagnosis, and treatment. Get the latest information on hot topics such as Disseminated Intravascular Coagulation, Thrombophilia, Clinical and Laboratory Assessment and Management, Thrombotic -Thrombocytopenic Purpura, and Heparin-Induced Thrombocytopenia. Apply today’s newest therapies, including those that are quickly becoming standard in this fast-changing field. Meet the needs of specific patient groups with a new chapter on Bleeding and the Management of Hemorrhagic Disorders in Pregnancy and an extensively updated chapter on Thrombosis and Cancer. Zero in on key information with a new user-friendly design, and all-new full-color format, abundant laboratory protocols, and at-a-glance tables and charts throughout.

Molecular and Cellular Changes in the Cancer Cell

Author :
Publisher : Academic Press
ISBN 13 : 0128096039
Total Pages : 618 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Molecular and Cellular Changes in the Cancer Cell by :

Download or read book Molecular and Cellular Changes in the Cancer Cell written by and published by Academic Press. This book was released on 2016-11-16 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular and Cellular Changes in the Cancer Cell,the latest volume in the Progress in Molecular Biology and Translational Science series, includes a comprehensive summary of the evidence accumulated thus far on the molecular and cellular regulation of the various adaptations taking place in response to exercise. This volume examines some of the latest advances, highlighting some of the most important molecular and cellular alterations and environmental influences that collectively cause a normal cell to become cancerous. Special emphasis is given to changes that take place at the molecular and cellular level. Comprehensive and up-to-date survey of current knowledge on the cancer cell Includes the latest advances and the most important molecular and cellular alterations and environmental influences collectively causing cells to become cancerous Written by leading experts in the field

Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy

Author :
Publisher : Academic Press
ISBN 13 : 0128127384
Total Pages : 292 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy by :

Download or read book Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy written by and published by Academic Press. This book was released on 2018-11-21 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tyrosine Kinase Inhibitors as Sensitizing Agents for Chemotherapy, the fourth volume in the Cancer Sensitizing Agents for Chemotherapy Series, focuses on strategic combination therapies that involve a variety of tyrosine kinase inhibitors working together to overcome multi-drug resistance in cancer cells. The book discusses several tyrosine kinase inhibitors that have been used as sensitizing agents, such as EGFR, BCR-ABL, ALK and BRAF. In each chapter, readers will find comprehensive knowledge on the inhibitor and its action, including its biochemical, genetic, and molecular mechanisms' emphases. This book is a valuable source for oncologists, cancer researchers and those interested in applying new sensitizing agents to their research in clinical practice and in trials. Summarizes the sensitizing role of some tyrosine kinase inhibitors in existing research Brings recent findings in several cancer types, both experimental and clinically, with a particular emphases on underlying biochemical, genetic, and molecular mechanisms Provides an updated and comprehensive knowledge regarding the field of combinational cancer treatment