Myelination And Myelin Disorders

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Magnetic Resonance of Myelin, Myelination, and Myelin Disorders

Author : Jacob Valk
Publisher : Springer Science & Business Media
ISBN 13 : 366202568X
Total Pages : 734 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Magnetic Resonance of Myelin, Myelination, and Myelin Disorders by : Jacob Valk

Download or read book Magnetic Resonance of Myelin, Myelination, and Myelin Disorders written by Jacob Valk and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 734 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic resonance imaging (MRI) is now considered the imaging modality of choice for the majority of disorders affecting the central nervous system. This is particularly true for gray and white matter disorders, thanks to the superb soft tis sue contrast in MRI which allows gray matter, unmyelinated, and myelinated white matter to be distinguished and their respective disorders identified. The pre sent book is devoted to the disorders of myelin and myelination. A growing amount of detailed in vivo information about myelin, myelination, and myelin dis orders has been derived both from MRI and from MR spectroscopy (MRS). This prompted us to review the clinical, laboratory, biochemical, and pathological data on this subject in order to integrate all available information and to provide im proved insights into normal and disordered myelin and myelination. We will show how the synthesis of all available information contributes to the interpretation of MR images. After a brief historical review about the increasing knowledge on myelin and my elin disorders, we propose a new classification of myelin disorders based on the subcellular localization of the enzymatic defects as far as the inborn errors of me tabolism are concerned. This classification serves as a guide throughout the book. All items of the classification will be discussed and, whenever relevant and possi ble, be illustrated by MR images.

Diseases of the Brain, Head and Neck, Spine 2020–2023

Author : Juerg Hodler
Publisher : Springer Nature
ISBN 13 : 303038490X
Total Pages : 252 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Diseases of the Brain, Head and Neck, Spine 2020–2023 by : Juerg Hodler

Download or read book Diseases of the Brain, Head and Neck, Spine 2020–2023 written by Juerg Hodler and published by Springer Nature. This book was released on 2020-02-14 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.

Netter's Atlas of Neuroscience

Author : David L. Felten
Publisher : Elsevier Health Sciences
ISBN 13 : 0323265111
Total Pages : 499 pages
Book Rating : 4.3/5 (232 download)

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Book Synopsis Netter's Atlas of Neuroscience by : David L. Felten

Download or read book Netter's Atlas of Neuroscience written by David L. Felten and published by Elsevier Health Sciences. This book was released on 2015-11-30 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ideal for students of neuroscience and neuroanatomy, the new edition of Netter's Atlas of Neuroscience combines the didactic well-loved illustrations of Dr. Frank Netter with succinct text and clinical points, providing a highly visual, clinically oriented guide to the most important topics in this subject. The logically organized content presents neuroscience from three perspectives: an overview of the nervous system, regional neuroscience, and systemic neuroscience, enabling you to review complex neural structures and systems from different contexts. You may also be interested in: A companion set of flash cards, Netter's Neuroscience Flash Cards, 3rd Edition, to which the textbook is cross-referenced. Coverage of both regional and systemic neurosciences allows you to learn structure and function in different and important contexts. Combines the precision and beauty of Netter and Netter-style illustrations to highlight key neuroanatomical concepts and clinical correlations. Reflects the current understanding of the neural components and supportive tissue, regions, and systems of the brain, spinal cord, and periphery. Uniquely informative drawings provide a quick and memorable overview of anatomy, function, and clinical relevance. Succinct and useful format utilizes tables and short text to offer easily accessible "at-a-glance" information. Provides an overview of the basic features of the spinal cord, brain, and peripheral nervous system, the vasculature, meninges and cerebrospinal fluid, and basic development. Integrates the peripheral and central aspects of the nervous system. Bridges neuroanatomy and neurology through the use of correlative radiographs. Highlights cross-sectional brain stem anatomy and side-by-side comparisons of horizontal sections, CTs and MRIs. Features video of radiograph sequences and 3D reconstructions to enhance your understanding of the nervous system. Student Consult eBook version included with purchase. This enhanced eBook experience includes access -- on a variety of devices -- to the complete text, 14 videos, and images from the book. Expanded coverage of cellular and molecular neuroscience provides essential guidance on signaling, transcription factors, stem cells, evoked potentials, neuronal and glial function, and a number of molecular breakthroughs for a better understanding of normal and pathologic conditions of the nervous system. Micrographs, radiologic imaging, and stained cross sections supplement illustrations for a comprehensive visual understanding. Increased clinical points -- from sleep disorders and inflammation in the CNS to the biology of seizures and the mechanisms of Alzheimer's -- offer concise insights that bridge basic neuroscience and clinical application.

Atlas of Gross Neuropathology Book and Online Bundle

Author : Kathreena M. Kurian
Publisher : Cambridge University Press
ISBN 13 : 1107038162
Total Pages : 243 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Atlas of Gross Neuropathology Book and Online Bundle by : Kathreena M. Kurian

Download or read book Atlas of Gross Neuropathology Book and Online Bundle written by Kathreena M. Kurian and published by Cambridge University Press. This book was released on 2014-08-21 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unparalleled access to the entire central nervous system with over four hundred gross neuropathology images from adult and paediatric post-mortem tissues.

Myelin

Author : Bernard Zalc
Publisher : Oxford University Press
ISBN 13 : 0190686111
Total Pages : 333 pages
Book Rating : 4.1/5 (96 download)

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Book Synopsis Myelin by : Bernard Zalc

Download or read book Myelin written by Bernard Zalc and published by Oxford University Press. This book was released on 2018-08-22 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emergence of myelin 425 million years ago marked a turning point in evolution. Consider for a moment the invention of insulated wire, which allows for the transmission of electrical current. Functioning in a similar way, the membrane surrounding nerve fibers, or myelin, enables the remarkable acceleration of nerve impulses. Surprisingly, myelin occupies nearly half the volume of the human brain and is critical for our intellectual and motor performance. Without myelin, our thoughts and our movements would suffer overwhelming delays. We owe our reflexes to myelin: it is what makes us brake when a child dashes out onto the road, or snatch away a hand absent-mindedly placed on a burning hot stove. When damaged, myelin can lead to irreversible disability, cognitive decline, and sensory impairments. The study of myelin's role in the conduction of nerve impulses has led to a better understanding of several diseases including multiple sclerosis, Guillain-Barre syndrome, Charcot disease (ALS), and Niemann-Pick disease.

Neuroproteomics

Author : Oscar Alzate
Publisher : CRC Press
ISBN 13 : 1420076264
Total Pages : 356 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Neuroproteomics by : Oscar Alzate

Download or read book Neuroproteomics written by Oscar Alzate and published by CRC Press. This book was released on 2009-10-26 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this, the post-genomic age, our knowledge of biological systems continues to expand and progress. As the research becomes more focused, so too does the data. Genomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we beg

Magnetic Resonance of Myelination and Myelin Disorders

Author : Marjo S. van der Knaap
Publisher : Springer Science & Business Media
ISBN 13 : 3540276602
Total Pages : 1097 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Magnetic Resonance of Myelination and Myelin Disorders by : Marjo S. van der Knaap

Download or read book Magnetic Resonance of Myelination and Myelin Disorders written by Marjo S. van der Knaap and published by Springer Science & Business Media. This book was released on 2005-08-15 with total page 1097 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our thanks go to our colleagues at the VU Univer- Preface to the Third Edition sity Medical Center and to those in other hospitals Reading through the prefaces of the two previous edi- who referred their patients to us. We are indebted to tions,we can say that much of what was said there still all colleagues who allowed us to use their MR images, holds. At the same time,however,much has changed. published or unpublished,making it possible for us to There has been immense progress in the technical present illustrations of nearly all known white matter possibilities of magnetic resonance and in the know- disorders. Two colleagues were particularly helpful ledge of genetic defects, biochemical abnormalities, and provided us with essential and unpublished f- and cellular processes underlying myelin disorders. ures: our friends Susan Blaser,from the Hospital for This immense progress has prompted us to embark Sick Children in Toronto,and Zoltán Patay,from the upon the enormous task of rewriting the previous King Faisal Hospital in Riyadh. edition and adding 40 chapters. In doing so we have Many people at the VU University Medical Center tried to cover most white matter disorders,hereditary have been of great technical help to us in producing and acquired,and to present a collection of images to high quality images and in providing secretarial illustrate the field to the fullest possible extent. This assistance. The contributions of these people are edition will therefore be more complete than the pre- mentioned separately in the acknowledgements.

Myelin

Author : Russell E. Martenson
Publisher : CRC Press
ISBN 13 : 9780849388491
Total Pages : 1006 pages
Book Rating : 4.3/5 (884 download)

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Book Synopsis Myelin by : Russell E. Martenson

Download or read book Myelin written by Russell E. Martenson and published by CRC Press. This book was released on 1992-02-20 with total page 1006 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myelin: Biology and Chemistry provides in-depth reviews and discussions regarding recent findings in the biology and chemistry of myelin. Topics are interdisciplinary and carry readers from the cellular level to that of the gene. Research in demyelinating diseases (naturally occurring and experimentally produced) is described and emphasizes autoimmune and virally induced mechanisms. Advances in molecular biology, such as those that provide details of the structures of the major myelin proteins, demonstrate the control of their synthesis, and explore the mutations within their genes that disrupt the process of myelination, are discussed in depth. Myelin: Biology and Chemistry will be an important addition to the libraries of molecular biologists, biochemists, cell biologists, physical chemists, immunologists, virologists, and pathologists involved in the study of myelin.

Multiple Sclerosis

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309072859
Total Pages : 457 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Multiple Sclerosis by : Institute of Medicine

Download or read book Multiple Sclerosis written by Institute of Medicine and published by National Academies Press. This book was released on 2001-08-10 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives. The panel reviews existing knowledge and identifies key research questions, focusing on: Research strategies that have the greatest potential to understand the biological mechanisms of recovery and to translate findings into specific strategies for therapy. How people adapt to MS and the research needed to improve the lives of people with MS. Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others). The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families.

White Matter Dementia

Author : Christopher M. Filley
Publisher : Cambridge University Press
ISBN 13 : 1107035414
Total Pages : 231 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis White Matter Dementia by : Christopher M. Filley

Download or read book White Matter Dementia written by Christopher M. Filley and published by Cambridge University Press. This book was released on 2016-04-28 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presenting the novel concept of white matter dementia, this unique book offers hope for a better understanding and treatment of dementia.

Multiple Sclerosis As A Neuronal Disease

Author : Stephen Waxman
Publisher : Elsevier
ISBN 13 : 0080489419
Total Pages : 495 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Multiple Sclerosis As A Neuronal Disease by : Stephen Waxman

Download or read book Multiple Sclerosis As A Neuronal Disease written by Stephen Waxman and published by Elsevier. This book was released on 2005-05-27 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the role of neurons in multiple sclerosis (MS) and the changes that occur in neurons as a result of MS. It places MS in a new and important perspective that not only explains the basis for symptom production, remission, and progress in MS, but also promises to open up new therapeutic possibilities.* Brings together the latest information from clinical, pathological, imaging, molecular, and pharmacological realms to explore the neurobiology of Multiple Sclerosis* Places MS in a new and important perspective that promises to open up new therapeutic avenues* Superbly illustrated and referenced

Magnetic Resonance of Myelin, Myelination and Myelin Disorders

Author : Marjo S. van der Knaap
Publisher : Springer Science & Business Media
ISBN 13 : 3662030780
Total Pages : 1255 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Magnetic Resonance of Myelin, Myelination and Myelin Disorders by : Marjo S. van der Knaap

Download or read book Magnetic Resonance of Myelin, Myelination and Myelin Disorders written by Marjo S. van der Knaap and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 1255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clearly structured, each chapter describes: * clinical features and laboratory investigations * pathology * pathogenetic considerations * therapy * case presentation * MRI and spectroscopy of a specific myelin disorder Completely updated and expanded by 20 chapters to include the latest information on: - inborn errors of metabolism and neurodegenerative disorders - the role of subcellular structures - enzyme biochemistry - the pathophysiological mechanisms of posthypoxic-ischemic cerebral damage - inflammatory and infectious disorders Plus: Greater coverage of the genetic and pathophysiological mechanisms underlying white matter disorders. Finally: 250 high-quality illustrations depict rare disorders which previously were only described.

Neurologic Differential Diagnosis

Author : Alan B. Ettinger
Publisher : Cambridge University Press
ISBN 13 : 1107014557
Total Pages : 693 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Neurologic Differential Diagnosis by : Alan B. Ettinger

Download or read book Neurologic Differential Diagnosis written by Alan B. Ettinger and published by Cambridge University Press. This book was released on 2014-04-17 with total page 693 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unique case-based guide to generating diagnostic possibilities based on the patients' symptoms. Invaluable for psychiatrists and neurologists.

Neuroprotection in Alzheimer's Disease

Author : Illana Gozes
Publisher : Academic Press
ISBN 13 : 0128037121
Total Pages : 344 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Neuroprotection in Alzheimer's Disease by : Illana Gozes

Download or read book Neuroprotection in Alzheimer's Disease written by Illana Gozes and published by Academic Press. This book was released on 2016-12-30 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroprotection in Alzheimer's Disease offers a translational point-of-view from both basic and clinical standpoints, putting it on the cusp for further clinical development with its emphasis on nerve cell protection, including the accumulation of knowledge from failed clinical trials and new advances in disease management. This book brings together the latest findings, both basic, and clinical, under the same cover, making it easy for the reader to obtain a complete overview of the state-of-the-field and beyond. Alzheimer's disease is the most common form of dementia, accounting for 60 to 80 percent of dementia cases. It is a progressive brain disease that slowly destroys memory, thinking skills, and eventually, even the ability to carry out the simplest tasks. It is characterized by death of synapses coupled to death nerve cells and brain degeneration which is manifested by loss of cognitive abilities. Understanding neuroprotection in Alzheimer's disease will pave the path to better disease management and novel therapeutics. - Comprehensive reference detailing neuroprotection in Alzheimer's Disease, with details on nerve cell protection and new advances in disease management - Combines the knowledge and points-of-view of both medical doctors and basic scientists, putting the subject at the forefront for further clinical development - Edited by one of the leading researchers in Alzheimer's Disease

Progressive Brain Disorders in Childhood

Author : Juan M. Pascual
Publisher : Cambridge University Press
ISBN 13 : 1107042054
Total Pages : 507 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Progressive Brain Disorders in Childhood by : Juan M. Pascual

Download or read book Progressive Brain Disorders in Childhood written by Juan M. Pascual and published by Cambridge University Press. This book was released on 2017-04-20 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: A review of childhood neurodegenerative and other progressive but non-degenerative disorders to guide their diagnosis and management.

The Biology of Oligodendrocytes

Author : Patricia Armati
Publisher : Cambridge University Press
ISBN 13 : 1139491717
Total Pages : pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis The Biology of Oligodendrocytes by : Patricia Armati

Download or read book The Biology of Oligodendrocytes written by Patricia Armati and published by Cambridge University Press. This book was released on 2010-10-21 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditionally, oligodendrocytes have been assumed to play a minor supporting role in the central nervous system and their importance has generally been overlooked. For the first time, this book provides a dedicated review of all of the major aspects of oligodendrocyte biology, including development, organization, genetics, and immunobiology. Later chapters emphasize the importance of this underestimated cell to the mammalian central nervous system by exploring the role of myelin synthesis and maintenance in neural disease and repair. Particular attention is paid to multiple sclerosis (MS), arguably the prime example of an acquired demyelinating disease, with detailed examinations of the current concepts regarding demyelination, oligodendroglial damage, and remyelination in MS lesions.

Handbook of Veterinary Neurology - E-Book

Author : Michael D. Lorenz
Publisher : Elsevier Health Sciences
ISBN 13 : 1437706525
Total Pages : 562 pages
Book Rating : 4.4/5 (377 download)

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Book Synopsis Handbook of Veterinary Neurology - E-Book by : Michael D. Lorenz

Download or read book Handbook of Veterinary Neurology - E-Book written by Michael D. Lorenz and published by Elsevier Health Sciences. This book was released on 2010-12-07 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Veterinary Neurology provides quick access to vital information on neurologic conditions in a wide range of species, including canine, feline, bovine, caprine, equine, ovine, and porcine. A problem-oriented approach makes it easy to diagnose and treat neurologic problems in small and large animals. The coverage of disorders by problem, not by established disease diagnosis, emulates how animals present to the veterinary hospital and simplifies the formulation of a correct diagnosis. Within each chapter, discussions of neurologic disease include a review of the localization criteria and the diseases that can cause that problem, plus treatment and surgical techniques. Lead author Michael D. Lorenz brings decades of experience to neurologic assessment, using a diagnostic approach that requires minimal knowledge of neuroanatomy. - A problem-based approach is organized by presenting sign rather than by condition, guiding you to logical conclusions regarding diagnosis and treatment. - Algorithms diagram the logic necessary to localize lesions and to formulate diagnostic plans. - Coverage of current diagnostic techniques includes the use of diagnostic tools, such as radiology, spinal fluid analysis, electrodiagnosis, and MR imaging. - Case histories in each chapter present a problem and the results of the neurologic examination, then ask you to solve the problem by localizing the lesion, listing probable causes, and making a diagnostic plan. Answers are provided at the back of the book. - A consistent format for each case history includes signalment, history, physical examination findings, and neurologic examination. - A comprehensive appendix describes species and breeds that have a congenital predisposition for particular neurologic diseases. - Extensive references make it easy to pursue in-depth research of more advanced topics. - A companion website includes 20 narrated video clips with accompanying PowerPoint slides that correlate to the case histories in the book, covering neurologic assessment and clinical problems such as paresis of one limb, tetraparesis, stupor, seizures, ataxia of the head and limbs, and cranial nerve disorders. - Two new co-authors, Jean Coates and Marc Kent, board-certified in neurology, enhance the credibility of this edition. - A full-color design and numerous illustrations include enhanced images of neuroanatomy and pathology.