Muse Cells

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Muse Cells

Author : Mari Dezawa
Publisher : Springer
ISBN 13 : 4431568476
Total Pages : 315 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Muse Cells by : Mari Dezawa

Download or read book Muse Cells written by Mari Dezawa and published by Springer. This book was released on 2018-11-27 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the first comprehensive account of multilineage-differentiating stress-enduring (Muse) cells, a pluripotent and non-tumorigenic subpopulation of mesenchymal stem cells (MSCs) that have the ability to detect damage signals, migrate to damaged sites, and spontaneously differentiate into cells compatible with the affected tissue, thereby enabling repair of all tissue types. The coverage encompasses everything from the basic properties of Muse cells to their tissue repair effects and potential clinical applications—for example, in acute myocardial infarction, stroke, skin injuries and ulcers, renal failure, and liver disease. An important technical chapter provides a practical and precise protocol for the isolation of Muse cells, which will enable readers to use Muse cells in their own research. In offering fascinating insights into the strategic organization of the body’s reparative function and explaining how full utilization of Muse cells may significantly enhance the effectiveness of MSC treatment, the book will be of high value for Ph.D. students, postdocs, basic researchers, clinical doctors, and industrial developers.

Cell Engineering and Regeneration

Author : Heinz Redl
Publisher : Springer
ISBN 13 : 9783319088303
Total Pages : 0 pages
Book Rating : 4.0/5 (883 download)

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Book Synopsis Cell Engineering and Regeneration by : Heinz Redl

Download or read book Cell Engineering and Regeneration written by Heinz Redl and published by Springer. This book was released on 2017-02-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference work presents the origins of cells for tissue engineering and regeneration, including primary cells, tissue-specific stem cells, pluripotent stem cells and trans-differentiated or reprogrammed cells. There is particular emphasis on current understanding of tissue regeneration based on embryology and evolution studies, including mechanisms of amphibian regeneration. The book covers the use of autologous versus allogeneic cell sources, as well as various procedures used for cell isolation and cell pre-conditioning , such as cell sorting, biochemical and biophysical pre-conditioning, transfection and aggregation. It also presents cell modulation using growth factors, molecular factors, epigenetic approaches, changes in biophysical environment, cellular co-culture and other elements of the cellular microenvironment. The pathways of cell delivery are discussed with respect to specific clinical situations, including delivery of ex vivo manipulated cells via local and systemic routes, as well as activation and migration of endogenous reservoirs of reparative cells. The volume concludes with an in-depth discussion of the tracking of cells in vivo and their various regenerative activities inside the body, including differentiation, new tissue formation and actions on other cells by direct cell-to-cell communication and by secretion of biomolecules.

Biological Relatives

Author : Sarah Franklin
Publisher : Duke University Press
ISBN 13 : 0822378256
Total Pages : 375 pages
Book Rating : 4.8/5 (223 download)

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Book Synopsis Biological Relatives by : Sarah Franklin

Download or read book Biological Relatives written by Sarah Franklin and published by Duke University Press. This book was released on 2013-11-15 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thirty-five years after its initial success as a form of technologically assisted human reproduction, and five million miracle babies later, in vitro fertilization (IVF) has become a routine procedure worldwide. In Biological Relatives, Sarah Franklin explores how the normalization of IVF has changed how both technology and biology are understood. Drawing on anthropology, feminist theory, and science studies, Franklin charts the evolution of IVF from an experimental research technique into a global technological platform used for a wide variety of applications, including genetic diagnosis, livestock breeding, cloning, and stem cell research. She contends that despite its ubiquity, IVF remains a highly paradoxical technology that confirms the relative and contingent nature of biology while creating new biological relatives. Using IVF as a lens, Franklin presents a bold and lucid thesis linking technologies of gender and sex to reproductive biomedicine, contemporary bioinnovation, and the future of kinship.

Silent Cells

Author : Anthony Ryan Hatch
Publisher : U of Minnesota Press
ISBN 13 : 1452960941
Total Pages : 240 pages
Book Rating : 4.4/5 (529 download)

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Book Synopsis Silent Cells by : Anthony Ryan Hatch

Download or read book Silent Cells written by Anthony Ryan Hatch and published by U of Minnesota Press. This book was released on 2019-04-30 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: A critical investigation into the use of psychotropic drugs to pacify and control inmates and other captives in the vast U.S. prison, military, and welfare systems For at least four decades, U.S. prisons and jails have aggressively turned to psychotropic drugs—antidepressants, antipsychotics, sedatives, and tranquilizers—to silence inmates, whether or not they have been diagnosed with mental illnesses. In Silent Cells, Anthony Ryan Hatch demonstrates that the pervasive use of psychotropic drugs has not only defined and enabled mass incarceration but has also become central to other forms of captivity, including foster homes, military and immigrant detention centers, and nursing homes. Silent Cells shows how, in shockingly large numbers, federal, state, and local governments and government-authorized private agencies pacify people with drugs, uncovering patterns of institutional violence that threaten basic human and civil rights. Drawing on publicly available records, Hatch unearths the coercive ways that psychotropics serve to manufacture compliance and docility, practices hidden behind layers of state secrecy, medical complicity, and corporate profiteering. Psychotropics, Hatch shows, are integral to “technocorrectional” policies devised to minimize public costs and increase the private profitability of mass captivity while guaranteeing public safety and national security. This broad indictment of psychotropics is therefore animated by a radical counterfactual question: would incarceration on the scale practiced in the United States even be possible without psychotropics?

Innovative Medicine

Author : Kazuwa Nakao
Publisher : Springer
ISBN 13 : 4431556516
Total Pages : 330 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Innovative Medicine by : Kazuwa Nakao

Download or read book Innovative Medicine written by Kazuwa Nakao and published by Springer. This book was released on 2015-10-13 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.

Scientific Principles of Adipose Stem Cells

Author : Lauren Kokai
Publisher : Academic Press
ISBN 13 : 0128193778
Total Pages : 486 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Scientific Principles of Adipose Stem Cells by : Lauren Kokai

Download or read book Scientific Principles of Adipose Stem Cells written by Lauren Kokai and published by Academic Press. This book was released on 2021-08-19 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific Principles of Adipose Stem Cells provides readers with in-depth and expert knowledge on adipose stem cells, their developmental biologic origins, foundational research on ASC signaling mechanisms and immunomodulatory properties, and clinical insights into applications in regenerative medicine. Topics covered include basic adipose stem cell developmental biology and mechanisms of regulating self-renewal and activation in the stem cell niche, important methods for isolation and characterizing ASCs, and data on the impact on human demographics (age, sex, BMI) on ASC phenotype. A section devoted to ASC biology, ASCs for stem cell therapy and regenerative medicine, and ASCs in tissue engineering applications are also included. The book is written for scientists and clinicians who are broadly familiar with stem cells and basic cell biology principles and those seeking advanced information on adipose stem cells. Coverage of basic adipose stem cell developmental biology (maturation process during embryogenesis) and mechanisms of regulating self-renewal and activation in the stem cell niche Includes important methods for isolation and characterizing ASCs, as well as known data any impact of human demographics (age, sex, BMI) on ASC phenotype An entire section dedicated to ASC biology, additional sections will be devoted to ASCs for stem cell therapy and regenerative medicine, as well as ASCs in tissue engineering applications

Is Cancer Inevitable?

Author : Ashani T. Weeraratna
Publisher : JHU Press
ISBN 13 : 1421442744
Total Pages : 155 pages
Book Rating : 4.4/5 (214 download)

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Book Synopsis Is Cancer Inevitable? by : Ashani T. Weeraratna

Download or read book Is Cancer Inevitable? written by Ashani T. Weeraratna and published by JHU Press. This book was released on 2021-12-07 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The author, a researcher in oncology, studies the cellular mechanisms of carcinogenesis. In this book written for a popular audience, the author takes a step back from the details of cells to look at the broader issue of how aging affects cancer"--

Culturing Life

Author : Hannah Landecker
Publisher : Harvard University Press
ISBN 13 : 9780674023284
Total Pages : 302 pages
Book Rating : 4.0/5 (232 download)

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Book Synopsis Culturing Life by : Hannah Landecker

Download or read book Culturing Life written by Hannah Landecker and published by Harvard University Press. This book was released on 2010-03-30 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: How did cells make the journey, one we take so much for granted, from their origin in living bodies to something that can be grown and manipulated on artificial media in the laboratory, a substantial biomass living outside a human body, plant, or animal? This is the question at the heart of Hannah Landecker's book. She shows how cell culture changed the way we think about such central questions of the human condition as individuality, hybridity, and even immortality and asks what it means that we can remove cells from the spatial and temporal constraints of the body and "harness them to human intention." Rather than focus on single discrete biotechnologies and their stories--embryonic stem cells, transgenic animals--Landecker documents and explores the wider genre of technique behind artificial forms of cellular life. She traces the lab culture common to all those stories, asking where it came from and what it means to our understanding of life, technology, and the increasingly blurry boundary between them. The technical culture of cells has transformed the meaning of the term "biological," as life becomes disembodied, distributed widely in space and time. Once we have a more specific grasp on how altering biology changes what it is to be biological, Landecker argues, we may be more prepared to answer the social questions that biotechnology is raising.

Cell Biology and Translational Medicine, Volume 11

Author : Kursad Turksen
Publisher : Springer Nature
ISBN 13 : 3030719251
Total Pages : 181 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Cell Biology and Translational Medicine, Volume 11 by : Kursad Turksen

Download or read book Cell Biology and Translational Medicine, Volume 11 written by Kursad Turksen and published by Springer Nature. This book was released on 2021-07-20 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the tenth volume of a continuing series.

Green Illusions

Author : Ozzie Zehner
Publisher : U of Nebraska Press
ISBN 13 : 0803243367
Total Pages : 462 pages
Book Rating : 4.8/5 (32 download)

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Book Synopsis Green Illusions by : Ozzie Zehner

Download or read book Green Illusions written by Ozzie Zehner and published by U of Nebraska Press. This book was released on 2012 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: We don’t have an energy crisis. We have a consumption crisis. And this book, which takes aim at cherished assumptions regarding energy, offers refreshingly straight talk about what’s wrong with the way we think and talk about the problem. Though we generally believe we can solve environmental problems with more energy—more solar cells, wind turbines, and biofuels—alternative technologies come with their own side effects and limitations. How, for instance, do solar cells cause harm? Why can’t engineers solve wind power’s biggest obstacle? Why won’t contraception solve the problem of overpopulation lying at the heart of our concerns about energy, and what will? This practical, environmentally informed, and lucid book persuasively argues for a change of perspective. If consumption is the problem, as Ozzie Zehner suggests, then we need to shift our focus from suspect alternative energies to improving social and political fundamentals: walkable communities, improved consumption, enlightened governance, and, most notably, women’s rights. The dozens of first steps he offers are surprisingly straightforward. For instance, he introduces a simple sticker that promises a greater impact than all of the nation’s solar cells. He uncovers why carbon taxes won’t solve our energy challenges (and presents two taxes that could). Finally, he explores how future environmentalists will focus on similarly fresh alternatives that are affordable, clean, and can actually improve our well-being. Watch a book trailer.

Nervous Fictions

Author : Jess Keiser
Publisher : University of Virginia Press
ISBN 13 : 0813944791
Total Pages : 425 pages
Book Rating : 4.8/5 (139 download)

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Book Synopsis Nervous Fictions by : Jess Keiser

Download or read book Nervous Fictions written by Jess Keiser and published by University of Virginia Press. This book was released on 2020-09-21 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The brain contains ten thousand cells," wrote the poet Matthew Prior in 1718, "in each some active fancy dwells." In the seventeenth and eighteenth centuries, just as scientists began to better understand the workings of the nerves, the nervous system became the site for a series of elaborate fantasies. The pineal gland is transformed into a throne for the sovereign soul. Animal spirits march the nerves like parading soldiers. An internal archivist searches through cerebral impressions to locate certain memories. An anatomist discovers that the brain of a fashionable man is stuffed full of beautiful clothes and billet-doux. A hypochondriac worries that his own brain will be disassembled like a watch. A sentimentalist sees the entire world as a giant nervous system comprising sympathetic spectators. Nervous Fictions is the first account of the Enlightenment origins of neuroscience and the "active fancies" it generated. By surveying the work of scientists (Willis, Newton, Cheyne), philosophers (Descartes, Cavendish, Locke), satirists (Swift, Pope), and novelists (Haywood, Fielding, Sterne), Keiser shows how attempts to understand the brain’s relationship to the mind produced in turn new literary forms. Early brain anatomists turned to tropes to explicate psyche and cerebrum, just as poets and novelists found themselves exploring new kinds of mental and physical interiority. In this respect, literary language became a tool to aid scientific investigation, while science spurred literary invention.

Vision's Immanence

Author : Peter Lurie
Publisher : JHU Press
ISBN 13 : 0801879299
Total Pages : 254 pages
Book Rating : 4.8/5 (18 download)

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Book Synopsis Vision's Immanence by : Peter Lurie

Download or read book Vision's Immanence written by Peter Lurie and published by JHU Press. This book was released on 2004-08 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Lurie takes particular interest in the influence of cinema on Faulkner's fiction and the visual strategies he both deployed and critiqued. These include the suggestion of cinematic viewing on the part of readers and of characters in each of the novels; the collective and individual acts of voyeurism in Sanctuary and Light in August; the exposing in Absalom! Absalom! and Light in August of stereotypical and cinematic patterns of thought about history and race; and the evocation of popular forms like melodrama and the movie screen in If I forget thee, Jerusalem. Offering innovative readings of these canonical works, this study sheds new light on Faulkner's uniquely American modernism."--BOOK JACKET.

Life as Surplus

Author : Melinda E. Cooper
Publisher : University of Washington Press
ISBN 13 : 0295990317
Total Pages : 233 pages
Book Rating : 4.2/5 (959 download)

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Book Synopsis Life as Surplus by : Melinda E. Cooper

Download or read book Life as Surplus written by Melinda E. Cooper and published by University of Washington Press. This book was released on 2011-02-01 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on the period between the 1970s and the present, Life as Surplus is a pointed and important study of the relationship between politics, economics, science, and cultural values in the United States today. Melinda Cooper demonstrates that the history of biotechnology cannot be understood without taking into account the simultaneous rise of neoliberalism as a political force and an economic policy. From the development of recombinant DNA technology in the 1970s to the second Bush administration's policies on stem cell research, Cooper connects the utopian polemic of free-market capitalism with growing internal contradictions of the commercialized life sciences. The biotech revolution relocated economic production at the genetic, microbial, and cellular level. Taking as her point of departure the assumption that life has been drawn into the circuits of value creation, Cooper underscores the relations between scientific, economic, political, and social practices. In penetrating analyses of Reagan-era science policy, the militarization of the life sciences, HIV politics, pharmaceutical imperialism, tissue engineering, stem cell science, and the pro-life movement, the author examines the speculative impulses that have animated the growth of the bioeconomy. At the very core of the new post-industrial economy is the transformation of biological life into surplus value. Life as Surplus offers a clear assessment of both the transformative, therapeutic dimensions of the contemporary life sciences and the violence, obligation, and debt servitude crystallizing around the emerging bioeconomy.

Genetics and the Unsettled Past

Author : Keith Wailoo
Publisher : Rutgers University Press
ISBN 13 : 0813553369
Total Pages : 371 pages
Book Rating : 4.8/5 (135 download)

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Book Synopsis Genetics and the Unsettled Past by : Keith Wailoo

Download or read book Genetics and the Unsettled Past written by Keith Wailoo and published by Rutgers University Press. This book was released on 2012-03-15 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our genetic markers have come to be regarded as portals to the past. Analysis of these markers is increasingly used to tell the story of human migration; to investigate and judge issues of social membership and kinship; to rewrite history and collective memory; to right past wrongs and to arbitrate legal claims and human rights controversies; and to open new thinking about health and well-being. At the same time, in many societies genetic evidence is being called upon to perform a kind of racially charged cultural work: to repair the racial past and to transform scholarly and popular opinion about the “nature” of identity in the present. Genetics and the Unsettled Past considers the alignment of genetic science with commercial genealogy, with legal and forensic developments, and with pharmaceutical innovation to examine how these trends lend renewed authority to biological understandings of race and history. This unique collection brings together scholars from a wide range of disciplines—biology, history, cultural studies, law, medicine, anthropology, ethnic studies, sociology—to explore the emerging and often contested connections among race, DNA, and history. Written for a general audience, the book’s essays touch upon a variety of topics, including the rise and implications of DNA in genealogy, law, and other fields; the cultural and political uses and misuses of genetic information; the way in which DNA testing is reshaping understandings of group identity for French Canadians, Native Americans, South Africans, and many others within and across cultural and national boundaries; and the sweeping implications of genetics for society today.

Good Science

Author : Charis Thompson
Publisher : MIT Press
ISBN 13 : 0262319047
Total Pages : 354 pages
Book Rating : 4.2/5 (623 download)

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Book Synopsis Good Science by : Charis Thompson

Download or read book Good Science written by Charis Thompson and published by MIT Press. This book was released on 2013-12-20 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: An examination of a decade and a half of political controversy, ethical debate, and scientific progress in stem cell research. After a decade and a half, human pluripotent stem cell research has been normalized. There may be no consensus on the status of the embryo—only a tacit agreement to disagree—but the debate now takes place in a context in which human stem cell research and related technologies already exist. In this book, Charis Thompson investigates the evolution of the controversy over human pluripotent stem cell research in the United States and proposes a new ethical approach for “good science.” Thompson traces political, ethical, and scientific developments that came together in what she characterizes as a “procurial” framing of innovation, based on concern with procurement of pluripotent cells and cell lines, a pro-cures mandate, and a proliferation of bio-curatorial practices. Thompson describes what she calls the “ethical choreography” that allowed research to go on as the controversy continued. The intense ethical attention led to some important discoveries as scientists attempted to “invent around” ethical roadblocks. Some ethical concerns were highly legible; but others were hard to raise in the dominant procurial framing that allowed government funding for the practice of stem cell research to proceed despite controversy. Thompson broadens the debate to include such related topics as animal and human research subjecthood and altruism. Looking at fifteen years of stem cell debate and discoveries, Thompson argues that good science and good ethics are mutually reinforcing, rather than antithetical, in contemporary biomedicine.

Brutes Or Angels

Author : James T. Bradley
Publisher : University of Alabama Press
ISBN 13 : 0817317880
Total Pages : 359 pages
Book Rating : 4.8/5 (173 download)

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Book Synopsis Brutes Or Angels by : James T. Bradley

Download or read book Brutes Or Angels written by James T. Bradley and published by University of Alabama Press. This book was released on 2013-04-02 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: "With stem cell research, Dolly the cloned sheep, in vitro fertilization, age retardation, and pharmaceutical mind enhancement, humankind is now faced with decisions that it has never before had to consider. The thoughtfulness, or lack of it, that we bring to those decisions will largely determine the future character of the living world. Brutes or Angels will facilitate informed choice making about the personal use of biotechnologies and the formulation of public policies governing their development and use. Ten biotechnologies that impact humans are considered: stem cell research, embryo selection, human genomics, gene therapies, human reproductive cloning, age retardation, cognition enhancement, the engineering of nonhuman organisms, nanobiology, and synthetic biology. With deft and assured use of metaphors, analogies, diagrams, and photographs, James T. Bradley introduces important biological principles and the basic procedures used in biotechnology. Various ethical issues--personhood, personal identity, privacy, ethnic discrimination, distributive justice, authenticity and human nature, and the significance of mortality in the human life cycle--are presented in a clear and unbiased manner. Personal reflection and group dialogue are encouraged by questions at the end of each chapter, making this book not only a general guide to better informed and nuanced thinking on these complex and challenging topics but also an appropriate text for bioethics courses in university science departments and for adult education classes." -- Publisher's description.

Interdependence

Author : Kriti Sharma
Publisher : Fordham Univ Press
ISBN 13 : 0823265544
Total Pages : 144 pages
Book Rating : 4.8/5 (232 download)

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Book Synopsis Interdependence by : Kriti Sharma

Download or read book Interdependence written by Kriti Sharma and published by Fordham Univ Press. This book was released on 2015-06-01 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: From biology to economics to information theory, the theme of interdependence is in the air, framing our experiences of all sorts of everyday phenomena. Indeed, the network may be the ascendant metaphor of our time. Yet precisely because the language of interdependence has become so commonplace as to be almost banal, we miss some of its most surprising and far-reaching implications. In Interdependence, biologist Kriti Sharma offers a compelling alternative to the popular view that interdependence simply means independent things interacting. Sharma systematically shows how interdependence entails the mutual constitution of one thing by another—how all things come into being only in a system of dependence on others. In a step-by-step account filled with vivid examples, Sharma shows how a coherent view of interdependence can help make sense not only of a range of everyday experiences but also of the most basic functions of living cells. With particular attention to the fundamental biological problem of how cells pick up signals from their surroundings, Sharma shows that only an account which replaces the perspective of “individual cells interacting with external environments” with one centered in interdependent, recursive systems can adequately account for how life works. This book will be of interest to biologists and philosophers, to theorists of science, of systems, and of cybernetics, and to anyone curious about how life works. Clear, concise, and insightful, Interdependence: Biology and Beyond explicitly offers a coherent and practical philosophy of interdependence and will help shape what interdependence comes to mean in the twenty-first century.