Multiple Imputation In The Presence Of A Detection Limit With Applications

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Proceedings of the 1st International Conference on Quantitative, Social, Biomedical & Economic Issues 2017

Author : Christos C. Frangos
Publisher : Christos Frangos
ISBN 13 : 6188298008
Total Pages : 285 pages
Book Rating : 4.1/5 (882 download)

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Book Synopsis Proceedings of the 1st International Conference on Quantitative, Social, Biomedical & Economic Issues 2017 by : Christos C. Frangos

Download or read book Proceedings of the 1st International Conference on Quantitative, Social, Biomedical & Economic Issues 2017 written by Christos C. Frangos and published by Christos Frangos. This book was released on 2017-06-29 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present Conference is the 1st conference in a series of conferences to come with main topic quantitative methods in the social sciences. The purpose of the conference is to present and publish research output of all the Universities and Technological Institutions of Greece and the different nations of the World. Another important purpose is to facilitate the interaction between two worlds: the world of Business and the world of Academic Community. The organizers of this Conference have the ambition to establish a forum for discussions on the theory and applications of the Quantitative and Qualitative Methods in the different business sectors such as Small to Medium Enterprises or large Companies in Industry, Commerce, Tourism, Health, Public Sector, Shipping Industry and financial services. The Proceedings of the conference have an ISBN number.

Environmental Health Perspectives

Author :
Publisher :
ISBN 13 :
Total Pages : 1252 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Environmental Health Perspectives by :

Download or read book Environmental Health Perspectives written by and published by . This book was released on 2004 with total page 1252 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Chemometrics with R

Author : Ron Wehrens
Publisher : Springer Nature
ISBN 13 : 3662620278
Total Pages : 315 pages
Book Rating : 4.6/5 (626 download)

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Book Synopsis Chemometrics with R by : Ron Wehrens

Download or read book Chemometrics with R written by Ron Wehrens and published by Springer Nature. This book was released on 2020-08-20 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers readers an accessible introduction to the world of multivariate statistics in the life sciences, providing a comprehensive description of the general data analysis paradigm, from exploratory analysis (principal component analysis, self-organizing maps and clustering) to modeling (classification, regression) and validation (including variable selection). It also includes a special section discussing several more specific topics in the area of chemometrics, such as outlier detection, and biomarker identification. The corresponding R code is provided for all the examples in the book; and scripts, functions and data are available in a separate R package. This second revised edition features not only updates on many of the topics covered, but also several sections of new material (e.g., on handling missing values in PCA, multivariate process monitoring and batch correction).

Quantitative Methods for HIV/AIDS Research

Author : Cliburn Chan
Publisher : CRC Press
ISBN 13 : 1498734251
Total Pages : 309 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Quantitative Methods for HIV/AIDS Research by : Cliburn Chan

Download or read book Quantitative Methods for HIV/AIDS Research written by Cliburn Chan and published by CRC Press. This book was released on 2017-08-07 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative Methods in HIV/AIDS Research provides a comprehensive discussion of modern statistical approaches for the analysis of HIV/AIDS data. The first section focuses on statistical issues in clinical trials and epidemiology that are unique to or particularly challenging in HIV/AIDS research; the second section focuses on the analysis of laboratory data used for immune monitoring, biomarker discovery and vaccine development; the final section focuses on statistical issues in the mathematical modeling of HIV/AIDS pathogenesis, treatment and epidemiology. This book brings together a broad perspective of new quantitative methods in HIV/AIDS research, contributed by statisticians and mathematicians immersed in HIV research, many of whom are current or previous leaders of CFAR quantitative cores. It is the editors’ hope that the work will inspire more statisticians, mathematicians and computer scientists to collaborate and contribute to the interdisciplinary challenges of understanding and addressing the AIDS pandemic.

Flexible Imputation of Missing Data, Second Edition

Author : Stef van Buuren
Publisher : CRC Press
ISBN 13 : 0429960352
Total Pages : 444 pages
Book Rating : 4.4/5 (299 download)

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Book Synopsis Flexible Imputation of Missing Data, Second Edition by : Stef van Buuren

Download or read book Flexible Imputation of Missing Data, Second Edition written by Stef van Buuren and published by CRC Press. This book was released on 2018-07-17 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Missing data pose challenges to real-life data analysis. Simple ad-hoc fixes, like deletion or mean imputation, only work under highly restrictive conditions, which are often not met in practice. Multiple imputation replaces each missing value by multiple plausible values. The variability between these replacements reflects our ignorance of the true (but missing) value. Each of the completed data set is then analyzed by standard methods, and the results are pooled to obtain unbiased estimates with correct confidence intervals. Multiple imputation is a general approach that also inspires novel solutions to old problems by reformulating the task at hand as a missing-data problem. This is the second edition of a popular book on multiple imputation, focused on explaining the application of methods through detailed worked examples using the MICE package as developed by the author. This new edition incorporates the recent developments in this fast-moving field. This class-tested book avoids mathematical and technical details as much as possible: formulas are accompanied by verbal statements that explain the formula in accessible terms. The book sharpens the reader’s intuition on how to think about missing data, and provides all the tools needed to execute a well-grounded quantitative analysis in the presence of missing data.

Nondetects and Data Analysis

Author : Dennis R. Helsel
Publisher : Wiley-Interscience
ISBN 13 :
Total Pages : 276 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Nondetects and Data Analysis by : Dennis R. Helsel

Download or read book Nondetects and Data Analysis written by Dennis R. Helsel and published by Wiley-Interscience. This book was released on 2005 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: STATISTICS IN PRACTICE Statistical methods for interpreting and analyzing censored environmental data Nondetects And Data Analysis: Statistics for Censored Environmental Data provides solutions for environmental scientists and professionals who need to interpret and analyze data that fall below the laboratory detection limit. Adapting survival analysis methods that have been successfully used in medical and industrial research, the author demonstrates, for the first time, their practical applications for studies of trace chemicals in air, water, soils, and biota. Readers quickly become proficient in these methods through the use of real-world examples that are solved using MINITAB® Release 14, a popular statistical software package, as well as other commonly used software packages. Everything needed to master these innovative statistical methods is provided, including: Accompanying Web site featuring answers to book exercises and datasets, as well as MINITAB® macros to perform methods, which are not available in the commercial version Methods for data with multiple detection limits Solutions for research studies in which all data are below detection limits Techniques for constructing confidence, prediction, and tolerance intervals for data with nond-tects Methods for data with multiple detection limits Chapters are organized by objective, such as computing intervals, comparing groups, and correlations, which enables readers to more easily apply the text to their particular research and goals. Extensive references to the literature for more in-depth research are provided; however, the text itself avoids complex math and calculus making it accessible to anyone in the environmental sciences. Environmental scientists and professionals will find the hands-on guidance and practical examples invaluable.

Statistics for Censored Environmental Data Using Minitab and R

Author : Dennis R. Helsel
Publisher : John Wiley & Sons
ISBN 13 : 0470479884
Total Pages : 344 pages
Book Rating : 4.4/5 (74 download)

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Book Synopsis Statistics for Censored Environmental Data Using Minitab and R by : Dennis R. Helsel

Download or read book Statistics for Censored Environmental Data Using Minitab and R written by Dennis R. Helsel and published by John Wiley & Sons. This book was released on 2012-02-01 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the First Edition " . . . an excellent addition to an upper-level undergraduate course on environmental statistics, and . . . a 'must-have' desk reference for environmental practitioners dealing with censored datasets." —Vadose Zone Journal Statistics for Censored Environmental Data Using Minitab® and R, Second Edition introduces and explains methods for analyzing and interpreting censored data in the environmental sciences. Adapting survival analysis techniques from other fields, the book translates well-established methods from other disciplines into new solutions for environmental studies. This new edition applies methods of survival analysis, including methods for interval-censored data to the interpretation of low-level contaminants in environmental sciences and occupational health. Now incorporating the freely available R software as well as Minitab® into the discussed analyses, the book features newly developed and updated material including: A new chapter on multivariate methods for censored data Use of interval-censored methods for treating true nondetects as lower than and separate from values between the detection and quantitation limits ("remarked data") A section on summing data with nondetects A newly written introduction that discusses invasive data, showing why substitution methods fail Expanded coverage of graphical methods for censored data The author writes in a style that focuses on applications rather than derivations, with chapters organized by key objectives such as computing intervals, comparing groups, and correlation. Examples accompany each procedure, utilizing real-world data that can be analyzed using the Minitab® and R software macros available on the book's related website, and extensive references direct readers to authoritative literature from the environmental sciences. Statistics for Censored Environmental Data Using Minitab® and R, Second Edition is an excellent book for courses on environmental statistics at the upper-undergraduate and graduate levels. The book also serves as a valuable reference for??environmental professionals, biologists, and ecologists who focus on the water sciences, air quality, and soil science.

Model Rules of Professional Conduct

Author : American Bar Association. House of Delegates
Publisher : American Bar Association
ISBN 13 : 9781590318737
Total Pages : 216 pages
Book Rating : 4.3/5 (187 download)

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Book Synopsis Model Rules of Professional Conduct by : American Bar Association. House of Delegates

Download or read book Model Rules of Professional Conduct written by American Bar Association. House of Delegates and published by American Bar Association. This book was released on 2007 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Model Rules of Professional Conduct provides an up-to-date resource for information on legal ethics. Federal, state and local courts in all jurisdictions look to the Rules for guidance in solving lawyer malpractice cases, disciplinary actions, disqualification issues, sanctions questions and much more. In this volume, black-letter Rules of Professional Conduct are followed by numbered Comments that explain each Rule's purpose and provide suggestions for its practical application. The Rules will help you identify proper conduct in a variety of given situations, review those instances where discretionary action is possible, and define the nature of the relationship between you and your clients, colleagues and the courts.

Mixed Effects Models for Complex Data

Author : Lang Wu
Publisher : CRC Press
ISBN 13 : 9781420074086
Total Pages : 431 pages
Book Rating : 4.0/5 (74 download)

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Book Synopsis Mixed Effects Models for Complex Data by : Lang Wu

Download or read book Mixed Effects Models for Complex Data written by Lang Wu and published by CRC Press. This book was released on 2009-11-11 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although standard mixed effects models are useful in a range of studies, other approaches must often be used in correlation with them when studying complex or incomplete data. Mixed Effects Models for Complex Data discusses commonly used mixed effects models and presents appropriate approaches to address dropouts, missing data, measurement errors, censoring, and outliers. For each class of mixed effects model, the author reviews the corresponding class of regression model for cross-sectional data. An overview of general models and methods, along with motivating examples After presenting real data examples and outlining general approaches to the analysis of longitudinal/clustered data and incomplete data, the book introduces linear mixed effects (LME) models, generalized linear mixed models (GLMMs), nonlinear mixed effects (NLME) models, and semiparametric and nonparametric mixed effects models. It also includes general approaches for the analysis of complex data with missing values, measurement errors, censoring, and outliers. Self-contained coverage of specific topics Subsequent chapters delve more deeply into missing data problems, covariate measurement errors, and censored responses in mixed effects models. Focusing on incomplete data, the book also covers survival and frailty models, joint models of survival and longitudinal data, robust methods for mixed effects models, marginal generalized estimating equation (GEE) models for longitudinal or clustered data, and Bayesian methods for mixed effects models. Background material In the appendix, the author provides background information, such as likelihood theory, the Gibbs sampler, rejection and importance sampling methods, numerical integration methods, optimization methods, bootstrap, and matrix algebra. Failure to properly address missing data, measurement errors, and other issues in statistical analyses can lead to severely biased or misleading results. This book explores the biases that arise when naïve methods are used and shows which approaches should be used to achieve accurate results in longitudinal data analysis.

Compositional Data Analysis

Author : Vera Pawlowsky-Glahn
Publisher : John Wiley & Sons
ISBN 13 : 0470711353
Total Pages : 405 pages
Book Rating : 4.4/5 (77 download)

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Book Synopsis Compositional Data Analysis by : Vera Pawlowsky-Glahn

Download or read book Compositional Data Analysis written by Vera Pawlowsky-Glahn and published by John Wiley & Sons. This book was released on 2011-09-19 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is difficult to imagine that the statistical analysis of compositional data has been a major issue of concern for more than 100 years. It is even more difficult to realize that so many statisticians and users of statistics are unaware of the particular problems affecting compositional data, as well as their solutions. The issue of ``spurious correlation'', as the situation was phrased by Karl Pearson back in 1897, affects all data that measures parts of some whole, such as percentages, proportions, ppm and ppb. Such measurements are present in all fields of science, ranging from geology, biology, environmental sciences, forensic sciences, medicine and hydrology. This book presents the history and development of compositional data analysis along with Aitchison's log-ratio approach. Compositional Data Analysis describes the state of the art both in theoretical fields as well as applications in the different fields of science. Key Features: Reflects the state-of-the-art in compositional data analysis. Gives an overview of the historical development of compositional data analysis, as well as basic concepts and procedures. Looks at advances in algebra and calculus on the simplex. Presents applications in different fields of science, including, genomics, ecology, biology, geochemistry, planetology, chemistry and economics. Explores connections to correspondence analysis and the Dirichlet distribution. Presents a summary of three available software packages for compositional data analysis. Supported by an accompanying website featuring R code. Applied scientists working on compositional data analysis in any field of science, both in academia and professionals will benefit from this book, along with graduate students in any field of science working with compositional data.

Statistical Testing Strategies in the Health Sciences

Author : Albert Vexler
Publisher : CRC Press
ISBN 13 : 1315353016
Total Pages : 622 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Statistical Testing Strategies in the Health Sciences by : Albert Vexler

Download or read book Statistical Testing Strategies in the Health Sciences written by Albert Vexler and published by CRC Press. This book was released on 2017-12-19 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical Testing Strategies in the Health Sciences provides a compendium of statistical approaches for decision making, ranging from graphical methods and classical procedures through computationally intensive bootstrap strategies to advanced empirical likelihood techniques. It bridges the gap between theoretical statistical methods and practical procedures applied to the planning and analysis of health-related experiments. The book is organized primarily based on the type of questions to be answered by inference procedures or according to the general type of mathematical derivation. It establishes the theoretical framework for each method, with a substantial amount of chapter notes included for additional reference. It then focuses on the practical application for each concept, providing real-world examples that can be easily implemented using corresponding statistical software code in R and SAS. The book also explains the basic elements and methods for constructing correct and powerful statistical decision-making processes to be adapted for complex statistical applications. With techniques spanning robust statistical methods to more computationally intensive approaches, this book shows how to apply correct and efficient testing mechanisms to various problems encountered in medical and epidemiological studies, including clinical trials. Theoretical statisticians, medical researchers, and other practitioners in epidemiology and clinical research will appreciate the book’s novel theoretical and applied results. The book is also suitable for graduate students in biostatistics, epidemiology, health-related sciences, and areas pertaining to formal decision-making mechanisms.

Analyzing Compositional Data with R

Author : K. Gerald van den Boogaart
Publisher : Springer Science & Business Media
ISBN 13 : 3642368093
Total Pages : 269 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Analyzing Compositional Data with R by : K. Gerald van den Boogaart

Download or read book Analyzing Compositional Data with R written by K. Gerald van den Boogaart and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the statistical analysis of compositional data sets, i.e., data in percentages, proportions, concentrations, etc. The subject is covered from its grounding principles to the practical use in descriptive exploratory analysis, robust linear models and advanced multivariate statistical methods, including zeros and missing values, and paying special attention to data visualization and model display issues. Many illustrated examples and code chunks guide the reader into their modeling and interpretation. And, though the book primarily serves as a reference guide for the R package “compositions,” it is also a general introductory text on Compositional Data Analysis. Awareness of their special characteristics spread in the Geosciences in the early sixties, but a strategy for properly dealing with them was not available until the works of Aitchison in the eighties. Since then, research has expanded our understanding of their theoretical principles and the potentials and limitations of their interpretation. This is the first comprehensive textbook addressing these issues, as well as their practical implications with regard to software. The book is intended for scientists interested in statistically analyzing their compositional data. The subject enjoys relatively broad awareness in the geosciences and environmental sciences, but the spectrum of recent applications also covers areas like medicine, official statistics, and economics. Readers should be familiar with basic univariate and multivariate statistics. Knowledge of R is recommended but not required, as the book is self-contained.

Current Index to Statistics, Applications, Methods and Theory

Author :
Publisher :
ISBN 13 :
Total Pages : 948 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Current Index to Statistics, Applications, Methods and Theory by :

Download or read book Current Index to Statistics, Applications, Methods and Theory written by and published by . This book was released on 1999 with total page 948 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Current Index to Statistics (CIS) is a bibliographic index of publications in statistics, probability, and related fields.

Handbook of Statistical Data Editing and Imputation

Author : Ton de Waal
Publisher : John Wiley & Sons
ISBN 13 : 0470904836
Total Pages : 453 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Handbook of Statistical Data Editing and Imputation by : Ton de Waal

Download or read book Handbook of Statistical Data Editing and Imputation written by Ton de Waal and published by John Wiley & Sons. This book was released on 2011-03-04 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical, one-stop reference on the theory and applications of statistical data editing and imputation techniques Collected survey data are vulnerable to error. In particular, the data collection stage is a potential source of errors and missing values. As a result, the important role of statistical data editing, and the amount of resources involved, has motivated considerable research efforts to enhance the efficiency and effectiveness of this process. Handbook of Statistical Data Editing and Imputation equips readers with the essential statistical procedures for detecting and correcting inconsistencies and filling in missing values with estimates. The authors supply an easily accessible treatment of the existing methodology in this field, featuring an overview of common errors encountered in practice and techniques for resolving these issues. The book begins with an overview of methods and strategies for statistical data editing and imputation. Subsequent chapters provide detailed treatment of the central theoretical methods and modern applications, with topics of coverage including: Localization of errors in continuous data, with an outline of selective editing strategies, automatic editing for systematic and random errors, and other relevant state-of-the-art methods Extensions of automatic editing to categorical data and integer data The basic framework for imputation, with a breakdown of key methods and models and a comparison of imputation with the weighting approach to correct for missing values More advanced imputation methods, including imputation under edit restraints Throughout the book, the treatment of each topic is presented in a uniform fashion. Following an introduction, each chapter presents the key theories and formulas underlying the topic and then illustrates common applications. The discussion concludes with a summary of the main concepts and a real-world example that incorporates realistic data along with professional insight into common challenges and best practices. Handbook of Statistical Data Editing and Imputation is an essential reference for survey researchers working in the fields of business, economics, government, and the social sciences who gather, analyze, and draw results from data. It is also a suitable supplement for courses on survey methods at the upper-undergraduate and graduate levels.

Modern Proteomics – Sample Preparation, Analysis and Practical Applications

Author : Hamid Mirzaei
Publisher : Springer
ISBN 13 : 3319414488
Total Pages : 525 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Modern Proteomics – Sample Preparation, Analysis and Practical Applications by : Hamid Mirzaei

Download or read book Modern Proteomics – Sample Preparation, Analysis and Practical Applications written by Hamid Mirzaei and published by Springer. This book was released on 2016-12-14 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume serves as a proteomics reference manual, describing experimental design and execution. The book also shows a large number of examples as to what can be achieved using proteomics techniques. As a relatively young area of scientific research, the breadth and depth of the current state of the art in proteomics might not be obvious to all potential users. There are various books and review articles that cover certain aspects of proteomics but they often lack technical details. Subject specific literature also lacks the broad overviews that are needed to design an experiment in which all steps are compatible and coherent. The objective of this book was to create a proteomics manual to provide scientists who are not experts in the field with an overview of: 1. The types of samples can be analyzed by mass spectrometry for proteomics analysis. 2. Ways to convert biological or ecological samples to analytes ready for mass spectral analysis. 3. Ways to reduce the complexity of the proteome to achieve better coverage of the constituent proteins. 4. How various mass spectrometers work and different ways they can be used for proteomics analysis 5. The various platforms that are available for proteomics data analysis 6. The various applications of proteomics technologies in biological and medical sciences This book should appeal to anyone with an interest in proteomics technologies, proteomics related bioinformatics and proteomics data generation and interpretation. With the broad setup and chapters written by experts in the field, there is information that is valuable for students as well as for researchers who are looking for a hands on introduction into the strengths, weaknesses and opportunities of proteomics.

Cochrane Handbook for Systematic Reviews of Interventions

Author : Julian P. T. Higgins
Publisher : Wiley
ISBN 13 : 9780470699515
Total Pages : 672 pages
Book Rating : 4.6/5 (995 download)

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Book Synopsis Cochrane Handbook for Systematic Reviews of Interventions by : Julian P. T. Higgins

Download or read book Cochrane Handbook for Systematic Reviews of Interventions written by Julian P. T. Higgins and published by Wiley. This book was released on 2008-11-24 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: Healthcare providers, consumers, researchers and policy makers are inundated with unmanageable amounts of information, including evidence from healthcare research. It has become impossible for all to have the time and resources to find, appraise and interpret this evidence and incorporate it into healthcare decisions. Cochrane Reviews respond to this challenge by identifying, appraising and synthesizing research-based evidence and presenting it in a standardized format, published in The Cochrane Library (www.thecochranelibrary.com). The Cochrane Handbook for Systematic Reviews of Interventions contains methodological guidance for the preparation and maintenance of Cochrane intervention reviews. Written in a clear and accessible format, it is the essential manual for all those preparing, maintaining and reading Cochrane reviews. Many of the principles and methods described here are appropriate for systematic reviews applied to other types of research and to systematic reviews of interventions undertaken by others. It is hoped therefore that this book will be invaluable to all those who want to understand the role of systematic reviews, critically appraise published reviews or perform reviews themselves.

Missing Data in Clinical Studies

Author : Geert Molenberghs
Publisher : John Wiley & Sons
ISBN 13 : 9780470510438
Total Pages : 526 pages
Book Rating : 4.5/5 (14 download)

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Book Synopsis Missing Data in Clinical Studies by : Geert Molenberghs

Download or read book Missing Data in Clinical Studies written by Geert Molenberghs and published by John Wiley & Sons. This book was released on 2007-04-04 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: Missing Data in Clinical Studies provides a comprehensive account of the problems arising when data from clinical and related studies are incomplete, and presents the reader with approaches to effectively address them. The text provides a critique of conventional and simple methods before moving on to discuss more advanced approaches. The authors focus on practical and modeling concepts, providing an extensive set of case studies to illustrate the problems described. Provides a practical guide to the analysis of clinical trials and related studies with missing data. Examines the problems caused by missing data, enabling a complete understanding of how to overcome them. Presents conventional, simple methods to tackle these problems, before addressing more advanced approaches, including sensitivity analysis, and the MAR missingness mechanism. Illustrated throughout with real-life case studies and worked examples from clinical trials. Details the use and implementation of the necessary statistical software, primarily SAS. Missing Data in Clinical Studies has been developed through a series of courses and lectures. Its practical approach will appeal to applied statisticians and biomedical researchers, in particular those in the biopharmaceutical industry, medical and public health organisations. Graduate students of biostatistics will also find much of benefit.