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Author :
Publisher :
ISBN 13 :
Total Pages : 1072 pages
Book Rating : 4.B/5 (1 download)
Download or read book Congressional Record written by and published by . This book was released on 1891 with total page 1072 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : United States. Congress
Publisher :
ISBN 13 :
Total Pages : 1018 pages
Book Rating : 4.3/5 (121 download)
Download or read book Congressional Record written by United States. Congress and published by . This book was released on 1892 with total page 1018 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Henry Wilson Storey
Publisher :
ISBN 13 :
Total Pages : 948 pages
Book Rating : 4.:/5 (334 download)
Download or read book History of Cambria County, Pennsylvania written by Henry Wilson Storey and published by . This book was released on 1907 with total page 948 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Felipe Sierra
Publisher : Springer
ISBN 13 : 3319232460
Total Pages : 637 pages
Book Rating : 4.3/5 (192 download)
Download or read book Advances in Geroscience written by Felipe Sierra and published by Springer. This book was released on 2015-11-10 with total page 637 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the first comprehensive overview of a new scientific discipline termed Geroscience. Geroscience examines the molecular and cellular mechanisms that might explain why aging is the main risk factor for most chronic diseases affecting the elderly population. Over the past few decades, researchers have made impressive progress in understanding the genetics, biology and physiology of aging. This book presents vital research that can help readers to better understand how aging is a critical malleable risk factor in most chronic diseases, which, in turn, could lead to interventions that can help increase a healthy lifespan, or ‘healthspan.’ The book begins with an analysis of the Geroscience hypothesis, as well as the epidemiological underpinnings that define aging as a candidate main risk factor for most chronic diseases. Next, each chapter focuses on one particular disease, or group of diseases, with an emphasis on how basic molecular and cellular biology might explain why aging is a major risk factor for it. Coverage in the book includes: cancer, cardiovascular disease, dementias, stroke, Parkinson's and Alzheimer’s diseases, osteoporosis, arthritis, diabetes asthma, emphysema, kidney disease, vision impairment, and AIDS/HIV. It finishes with a chapter on pain in the elderly and an overview of future steps needed to bring the newly acquired knowledge into the clinic and the public at large.
Author : Salim Yusuf
Publisher : John Wiley & Sons
ISBN 13 : 0470986875
Total Pages : 1024 pages
Book Rating : 4.4/5 (79 download)
Download or read book Evidence-Based Cardiology written by Salim Yusuf and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 1024 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second editionis a ground-breaking clinical text with a strong emphasis on rigorous evidence. Leaders in the field discuss best practice in the light of systematic reviews and randomised control trials, and how best to treat where the information is less clear. Case histories provide intriguing discussions on how to apply the evidence in real life situations. Evidence-based Cardiology also includes free access to the latest evidence, which is automatically posted on a companion website.
Author : Fred E. Hahn
Publisher : Springer Science & Business Media
ISBN 13 : 3642464076
Total Pages : 484 pages
Book Rating : 4.6/5 (424 download)
Download or read book Mechanism of Action of Antieukaryotic and Antiviral Compounds written by Fred E. Hahn and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: When Antibiotics I was published in 1967, the teleological view was held by some that" antibiotics" were substances elaborated by certain microorgan isms for the purpose of competing with other microorganisms for survival in mixed ecological environments. However, not only had J. EHRLICH and his associates shown 15 years earlier that chloramphenicol was produced by Strepto myces venezuelae in cultures of sterilized soils but not in parallel cultures of the same soils which were not sterilized, but operationally, the search for anti cancer antibiotics was actively under way (Antibiotics I reporting on numerous such substances), although the concept of antibiosis could not logically justify such undertakings. This editor hesitates to accept the use of the term "antibiotic" for anti microbial agents of non microbiological origins which is sometimes encountered, but neither does he subscribe to the view that antibiotics are in some fundamental manner different from chemotherapeutic substances of other origins. Modes and mechanisms of action of chemotherapeutic compounds are not systematic functions of their origins nor of the taxonomical position of the target organisms. Consequently, in the selection of topics for Antibiotics III (published in 1975), synthetic drugs and natural products of higher plants (alkaloids) were represented, along with antibiotics in the strict sense of the definition. We now present Antibiotics V, for whose assembly the same selection criteria were applied as for Antibiotics Ill. The aggregate length of the contributions rendered it impractical to place the entire text between the covers of one book.
Author : Illinois. Court of Claims
Publisher :
ISBN 13 :
Total Pages : 154 pages
Book Rating : 4.3/5 (511 download)
Download or read book Reports of Cases Argued and Determined in the Court of Claims of the State of Illinois written by Illinois. Court of Claims and published by . This book was released on 1916 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : William R. Warnock
Publisher :
ISBN 13 :
Total Pages : 20 pages
Book Rating : 4.A/5 ( download)
Download or read book The Army Appropriation Bill written by William R. Warnock and published by . This book was released on 1902 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : International Atomic Energy Agency
Publisher : IAEA
ISBN 13 :
Total Pages : 704 pages
Book Rating : 4.3/5 (91 download)
Download or read book Radiation Oncology Physics written by International Atomic Energy Agency and published by IAEA. This book was released on 2005 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication is aimed at students and teachers involved in teaching programmes in field of medical radiation physics, and it covers the basic medical physics knowledge required in the form of a syllabus for modern radiation oncology. The information will be useful to those preparing for professional certification exams in radiation oncology, medical physics, dosimetry or radiotherapy technology.
Author : Fan Lin
Publisher : Springer
ISBN 13 : 1493915789
Total Pages : 756 pages
Book Rating : 4.4/5 (939 download)
Download or read book Handbook of Practical Immunohistochemistry written by Fan Lin and published by Springer. This book was released on 2015-02-21 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a conceptually current, quick-reference, Question & Answer format, the second edition of Handbook of Practical Immunohistochemistry: Frequently Asked Questions continues to provide a comprehensive and yet concise state-of-the-art overview of the major issues specific to the field of immunohistochemistry. With links to the authors Immunohistochemical Laboratory website, this volume creates a current and up-to-date information system on immunohistochemistry. This includes access to tissue microarrays (TMA) of over 10,000 tumors and normal tissue to validate common diagnostic panels and provide the best reproducible data for diagnostic purposes. Fully revised and updated from the first edition, the new features of the second edition include over 200 additional questions or revised questions with an IHC panel to answer each question; over 250 new color photos and illustrations; over 20 new useful biomarkers; hundreds of new references; several new chapters to cover phosphoproteins, rabbit monoclonal antibodies, multiplex IHC stains, overview of predictive biomarkers, and integration of IHC into molecular pathology; many new coauthors who are international experts in a related field; many updated IHC panels using Geisinger IHC data collected from over 10,000 tumors and normal tissues; and updated appendices containing detailed antibody information for both manual and automated staining procedures. Comprehensive yet practical and concise, the Handbook of Practical Immunohistochemistry: Frequently Asked Questions, Second Edition will be of great value for surgical pathologists, pathology residents and fellows, cytopathologists, and cytotechnologists.
Author : Scott M. Auerbach
Publisher : CRC Press
ISBN 13 : 1135538034
Total Pages : 527 pages
Book Rating : 4.1/5 (355 download)
Download or read book Handbook of Layered Materials written by Scott M. Auerbach and published by CRC Press. This book was released on 2004-03-23 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on layered compounds at the core of materials intercalation chemistry, this reference comprehensively explores clays and other classes of materials exhibiting the ability to pillar, or establish permanent intracrystalline porosity within layers. It offers an authoritative presentation of their fundamental properties as well as summaries of
Author : Jeffrey Wang
Publisher : Springer
ISBN 13 : 3319130811
Total Pages : 248 pages
Book Rating : 4.3/5 (191 download)
Download or read book Antibody-Drug Conjugates written by Jeffrey Wang and published by Springer. This book was released on 2015-03-05 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative volume provides a holistic picture of antibody-drug conjugates (ADCs). Fourteen comprehensive chapters are divided into six sections including an introduction to ADCs, the ADC construct, development issues, landscape, IP and pharmacoeconomics, case studies, and the future of the field. The book examines everything from the selection of the antibody, the drug, and the linker to a discussion of developmental issues such as formulations, bio-analysis, pharmacokinetic-pharmacodynamic relationships, and toxicological and regulatory challenges. It also explores pharmacoecomonics and intellectual properties, including recently issued patents and the cost analysis of drug therapy. Case studies are presented for the three ADCs that have received FDA approval: gemtuzumab ozogamicin (Mylotarg®), Brentuximab vedotin (Adcetris®), and ado-trastuzumab emtansine (Kadcyla®), as well as an ADC in late-stage clinical trials, glembatumumab vedotin (CDX-011). Finally, the volume presents a perspective by the editors on the future directions of ADC development and clinical applications. Antibody-Drug Conjugates is a practical and systematic resource for scientists, professors, and students interested in expanding their knowledge of cutting-edge research in this exciting field.
Author : National Library of Medicine (U.S.)
Publisher :
ISBN 13 :
Total Pages : 88 pages
Book Rating : 4.:/5 (319 download)
Download or read book National Library of Medicine Programs and Services written by National Library of Medicine (U.S.) and published by . This book was released on 1981 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Carsten B. Schmidt-Weber
Publisher : Springer
ISBN 13 : 3319699687
Total Pages : 251 pages
Book Rating : 4.3/5 (196 download)
Download or read book Allergy Prevention and Exacerbation written by Carsten B. Schmidt-Weber and published by Springer. This book was released on 2018-01-25 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Allergy is developing into one of the most prevalent diseases affecting individuals in the very early days of life. While the cause of this epidemic is still unclear, it appears that the westernized life style is playing an important role, which includes nutrition, possibly air pollution as well as hygienic conditions. While epidemiologic studies were able to narrow down these factors, basic research discovered novel mechanisms that control the organism ́s tolerance against allergens. Particularly interesting is the role of microorganisms that colonize or infect a host and thereby cause damage and immunological activation followed by sensitization or exacerbation of already existing sensitizations. However at the same time microbial activation of the immune system can help to generate a protective immunity that prevents allergen sensitization. The current book is collecting these evidences and connects epidemiologic and clinical mechanistic knowledge. Only the synthesis of this knowledge will help to find solutions to the ongoing allergy epidemic in terms of public health activities, prevention and therapy.
Author : Claus-M. Naske
Publisher :
ISBN 13 :
Total Pages : 368 pages
Book Rating : 4.3/5 (555 download)
Download or read book Paving Alaska's Trails written by Claus-M. Naske and published by . This book was released on 1986 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traces the development of the structure of the Road Commission and describes how Alaska's road system grew from less than a dozen miles of wagon road shortly after the turn of the century, to a network of 10,000 miles of roads by the time the Commission went out of existence in 1956.
Author : K.W.A. Wirtz
Publisher : Springer
ISBN 13 : 9781461362395
Total Pages : 318 pages
Book Rating : 4.3/5 (623 download)
Download or read book New Developments in Lipid-Protein Interactions and Receptor Function written by K.W.A. Wirtz and published by Springer. This book was released on 2012-10-24 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: A NATO Advanced Study Institute on "New Developments in Lipid-Protein Interactions and Receptor Function" was held on the Island of Spetsai, Greece, from August 16-27, 1992. This Institute was organized to bring together researchers in the field of membrane organization and dynamics with those actively involved in studies on receptor function, signal transduction mechanisms and gene regulation. 2 Presentations and discussions focussed on the regulation of intracellular Ca +-levels, on the second messengers derived from inositol lipids and on the specific phospholipase C isozymes involved in these processes. A major focus was on G-proteins and the effect of lipid anchors on their function. These principles of regulation were further discussed in the context of receptors for acetylcholine, lysophosphatidic acid and low-density lipoproteins. In addition, various aspects of the genomic regulation of cell growth and differentiation by transcription factors were presented. These topics were put into perspective by discussing the most recent developments in lipid-protein interactions, protein insertion into membranes, membrane lipid organization and lipid dynamics as mediated by phospholipid transfer proteins. This book presents the content of the major lectures and a selection of the most relevant of the most important topics posters. These proceedings offer a comprehensive account presented during the course of the Institute. The book is intended to make these proceedings accessible to a large audience.
Author : Duncan McDonald
Publisher :
ISBN 13 :
Total Pages : 336 pages
Book Rating : 4.:/5 (89 download)
Download or read book In Pursuit of the Nez Perces written by Duncan McDonald and published by . This book was released on 1993 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:
