Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Molecular Mechanisms Of Oxygen Activation
Download Molecular Mechanisms Of Oxygen Activation full books in PDF, epub, and Kindle. Read online Molecular Mechanisms Of Oxygen Activation ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Molecular Mechanisms Of Oxygen Activation by : Osamu Hayaishi
Download or read book Molecular Mechanisms Of Oxygen Activation written by Osamu Hayaishi and published by Elsevier. This book was released on 2012-12-02 with total page 697 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Mechanisms of Oxygen Activation reviews some of the major advances that have been made in our understanding of the molecular mechanisms underlying oxygen activation, with emphasis on the role of oxygen activation in contemporary biological processes. The biological role of oxygenases in the metabolism of fatty acids and steroids is discussed, along with the functions of heme-containing dioxygenases, a-ketoglutarate-coupled dioxygenases, and pterin-requiring aromatic amino acid hydroxylases. This book is comprised of 14 chapters and begins with an overview of the general properties and biological functions of oxygenases, along with the chemical aspects of oxygen fixation reactions. The reader is then introduced to research concerning fatty acid and steroid oxygenases which has appeared in the literature since 1962, paying particular attention to the mechanism of oxygenation and the biosynthesis and metabolism of steroids. Subsequent chapters explore the biological functions of a variety of oxygenases such as heme-containing dioxygenases, copper-containing oxygenases, flavoprotein oxygenases, and pterin-requiring aromatic amino acid hydroxylases. Superoxide dismutase, cytochrome c oxidase, peroxidase, and bacterial monoxygenases are also considered. This monograph should serve as a valuable reference for biochemists as well as undergraduate and graduate students of biochemistry.
Book Synopsis Molecular Mechanisms of Oxygen Activation by : O Hayaishi (Ed)
Download or read book Molecular Mechanisms of Oxygen Activation written by O Hayaishi (Ed) and published by . This book was released on 1974 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Oxygen Complexes and Oxygen Activation by Transition Metals by : Arthur Martell
Download or read book Oxygen Complexes and Oxygen Activation by Transition Metals written by Arthur Martell and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph consists of manuscripts, summary statements, and poster abstracts submitted by invited speakers and poster contributors who participated in the symposium "Oxygen Complexes and Oxygen Activation by Transition Metals," held March 23-26, 1987, at Texas A&M University. This meeting was the fifth annual international symposium sponsored by the Texas A&M Industry-University Cooperative Chemistry Program (IUCCP). The co chairmen of the conference were Professors Arthur E. Martell and Donald T. Sawyer of the Texas A&M University Chemistry Department. The program was developed by an academic-industrial steering committee consisting of the co-chairmen and members appointed by the sponsoring chemical companies Dr. James F. Bradzil, The Standard Oil Company, Ohio; Dr. Jerry R. Ebner, Monsanto Company; Dr. Craig Murchison, Dow Chemical Company; Dr. Donald C. Olsen, Shell Development Company; Dr. Tim R. Ryan, Celanese Chemical Company; and Dr. Ron Sanderson, Texaco Chemical Company. The subject of this conference reflects the intense interest that has developed in academic institutions and industry on several aspects of dioxygen chemistry. These include the formation of dioxygen complexes and their applications in facilitated transport and oxygen separation; homo geneous and heterogeneous catalysis of oxidation; and oxygenation of organic substrates by molecular oxygen. The conference differs in two respects from several other symposia on dioxygen chemistry held during the past few years. First, there is extensive industrial participation, especially with respect to oxygen activation.
Book Synopsis Flavin-Dependent Enzymes: Mechanisms, Structures and Applications by :
Download or read book Flavin-Dependent Enzymes: Mechanisms, Structures and Applications written by and published by Academic Press. This book was released on 2020-09-21 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Enzymes, Volume 47, highlights new advances in the field, with this new volume presenting interesting chapters on The Multipurpose Family of Oxidases, Vanillyl alcohol oxidase, Choline oxidases, Aryl alcohol oxidase, D- and L-amino acid oxidases, Sugar oxidases, Phenolic Compounds hydroxylases, Baeyer-Villiger Monooxygenases, Flavin-dependent halogenases, Flavin-dependent dehalogenases, Styrene Monooxygenases, Bacterial luciferases, Cellobiose Dehydrogenases, Prenylated flavoenzymes, Ene-reductases, Flavoenzymes in Biocatalysis. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in The Enzymes series
Book Synopsis Regulation of Tissue Oxygenation, Second Edition by : Roland N. Pittman
Download or read book Regulation of Tissue Oxygenation, Second Edition written by Roland N. Pittman and published by Biota Publishing. This book was released on 2016-08-18 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Book Synopsis MECHANISM OF OXYGEN ACTIVATION AND HYDROXYLATION BY THE AROMATIC AMINO ACID HYDROXYLASES by : Jorge A. Pavon
Download or read book MECHANISM OF OXYGEN ACTIVATION AND HYDROXYLATION BY THE AROMATIC AMINO ACID HYDROXYLASES written by Jorge A. Pavon and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The aromatic amino acid hydroxylases phenylalanine hydroxylase (PheH), tyrosine hydroxylase (TyrH) and tryptophan hydroxylase (TrpH) utilize tetrahydropterin and molecular oxygen to catalyze aromatic hydroxylation. All three enzymes have similar active sites and contain an iron atom facially coordinated by two histidines and a glutamate. The three enzymes also catalyze the benzylic hydroxylation of 4- methylphenylalanine. The intrinsic primary and?-secondary isotope effects for benzylic hydroxylation and their temperature dependences are nearly identical for the three enzymes, suggesting that the transition states, the tunneling contributions and the reactivities of the iron centers are the same. When molecular oxygen and the tetrahydropterin are replaced by hydrogen peroxide (H2O2), these enzymes catalyze the hydroxylation of phenylalanine to form tyrosine and meta-tyrosine with nearly identical second order rate constants. When the H2O2-dependent reaction is carried out with cyclohexylalanine or 4-methylphenylalanine, the products are 4-HO-cyclohexylalanine and 4-hydroxymethylphenylalanine, respectively. These experiments provide further evidence that the intrinsic reactivities of the iron centers in these enzymes are the same. Wild-type PheH and the uncoupled mutant protein V379D exhibit normal and inverse isotope effects, respectively, with deuterated phenylalanines. When the reaction is monitored by stopped-flow absorbance spectroscopy, three steps are visible. The first step is the reversible binding of O2, the second step is 5-7 fold faster than the turnover number, setting a limiting value for the rate constant for O2 activation, and the last step is non-enzymatic. There is no burst in the pre-steady state formation of tyrosine. These results are consistent with formation of the new C-O bond to form tyrosine as the ratelimiting step of the reaction. The reaction of TrpH with both tryptophan and phenylalanine was studied by stopped-flow absorbance spectroscopy and rapid-quench product analysis. With either amino acid as substrate, four steps can be distinguished. The first step is the reversible binding of O2 to the Fe(II) center; this results in an absorbance signature with a maximum at 420 nm. This O2 complex decays with a rate constant that is 18-22 fold faster than the turnover number with either amino acid, setting a the lower limit for the rate constant for O2 activation. The rate constant for the third step agrees well with the pre-steady state of formation of 5-hydroxytryptophan or tyrosine from rapid-quench product analysis. The rate constant for the fourth step agrees well with the turnover number. Overall, these results show that O2 activation is fast and turnover with each amino acid is limited by hydroxylation and release of a product, with the former step being about 4-fold faster than the latter.
Book Synopsis Active Oxygen in Biochemistry by : Valentine Angelou
Download or read book Active Oxygen in Biochemistry written by Valentine Angelou and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of "Oxygen Activation" has attracted considerable interest recently, not only because it presents challenges in those fields of basic research that aim to understand the fundamental aspects of chemical and biological reactions that involve dioxygen, but also because of its wide range of practical implications in such diverse fields as medicine, synthesis of pharmaceuticals and other organic compounds, materials science, and atmospheric science. This is the second of two volumes that focus on the subject of oxygen activation, the first slanted toward chemistry and the second toward biological chemistry. We planned these volumes to be more general than many monographs of this sort, not as detailed summaries of the authors' own research but rather as general overviews of the field. Our choice of topics was strongly influenced by our syllabus for a course entitled "Oxygen Chemistry," which two of us have twice taught jointly at UCLA. Definition of important issues, horizons, and future prospects was an important goal, and, although totally comprehensive coverage was not possible, we believe that we have chosen a representative selection of research topics current to the field. We have targeted this work to a diverse audience ranging from professionals in fields from physics to medicine to beginning graduate students who are interested in rapidly acquiring the basics of this field.
Book Synopsis Singlet Molecular Oxygen by : Arthur P. Schaap
Download or read book Singlet Molecular Oxygen written by Arthur P. Schaap and published by . This book was released on 1976 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Molecular Mechanisms of Oxygen Toxicity by : EEC Concerted Action on Extracorporeal Oxygenation
Download or read book Molecular Mechanisms of Oxygen Toxicity written by EEC Concerted Action on Extracorporeal Oxygenation and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Antioxidants in Sport Nutrition by : Manfred Lamprecht
Download or read book Antioxidants in Sport Nutrition written by Manfred Lamprecht and published by CRC Press. This book was released on 2014-09-17 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.
Book Synopsis Comprehensive Natural Products III by :
Download or read book Comprehensive Natural Products III written by and published by Elsevier. This book was released on 2020-07-22 with total page 4266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Natural Products III, Third Edition, Seven Volume Set updates and complements the previous two editions, including recent advances in cofactor chemistry, structural diversity of natural products and secondary metabolites, enzymes and enzyme mechanisms and new bioinformatics tools. Natural products research is a dynamic discipline at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids and enzymes. This book reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine and to stimulate new ideas among the established natural products community. Provides readers with an in-depth review of current natural products research and a critical insight into the future direction of the field Bridges the gap in knowledge by covering developments in the field since the second edition published in 2010 Split into 7 sections on key topics to allow students, researchers and professionals to find relevant information quickly and easily Ensures that the knowledge within is easily understood by and applicable to a large audience
Book Synopsis Comprehensive Organic Synthesis by :
Download or read book Comprehensive Organic Synthesis written by and published by Newnes. This book was released on 2014-02-14 with total page 9815 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Comprehensive Organic Synthesis—winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers—builds upon the highly respected first edition in drawing together the new common themes that underlie the many disparate areas of organic chemistry. These themes support effective and efficient synthetic strategies, thus providing a comprehensive overview of this important discipline. Fully revised and updated, this new set forms an essential reference work for all those seeking information on the solution of synthetic problems, whether they are experienced practitioners or chemists whose major interests lie outside organic synthesis. In addition, synthetic chemists requiring the essential facts in new areas, as well as students completely new to the field, will find Comprehensive Organic Synthesis, Second Edition, Nine Volume Set an invaluable source, providing an authoritative overview of core concepts. Winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers Contains more than170 articles across nine volumes, including detailed analysis of core topics such as bonds, oxidation, and reduction Includes more than10,000 schemes and images Fully revised and updated; important growth areas—including combinatorial chemistry, new technological, industrial, and green chemistry developments—are covered extensively
Book Synopsis Thermodynamic, Kinetic and Mechanistic Investigations of Binding and Activation of Molecular Oxygen and Mesityl Nitrile Oxide by : Xiaochen Cai
Download or read book Thermodynamic, Kinetic and Mechanistic Investigations of Binding and Activation of Molecular Oxygen and Mesityl Nitrile Oxide written by Xiaochen Cai and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxygen activation and binding to two transition-metal systems: late transition-metal system Pd(L1)(L2) (L1= NHC, L2= NHC or PR3) and early transition-metal system V(N(tBu)Ar)3 (Ar = 3,5-Me2C6H3) was explored in order to gain information about the thermodynamics, kinetics and mechanism of O2 binding to metal complexes. In this work, a novel oxygen binding mode was discovered and the resulting complex Pd(IPr)2([eta]1-O2)2 was reported as the first [eta]1 oxygenation palladium complex. This reaction was further studied and a plausible mechanism of O2 binding to Pd(L1)(L2) system was proposed, in which the effect of ligands bulkiness and an equilibrium between [eta]1-Pd and [eta]2-Pd were highlighted. In addition, an early transition-metal peroxo complex V(N(tBu)Ar)3([eta]2-O2) has been prepared directly by reaction with O2. Its equilibrium with V(N(tBu)Ar)3([eta]1-O2) and its reactivity were investigated. Finally the binding and activation of a potent oxygen atom transfer reagent MesCNO were studied.
Book Synopsis Molecular Mechanisms of Reactive Oxygen Species and Antioxidants in Signal Transduction by : Waleed Miazy Mohamed Hassan
Download or read book Molecular Mechanisms of Reactive Oxygen Species and Antioxidants in Signal Transduction written by Waleed Miazy Mohamed Hassan and published by . This book was released on 1999 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Liquid Phase Aerobic Oxidation Catalysis by : Shannon S. Stahl
Download or read book Liquid Phase Aerobic Oxidation Catalysis written by Shannon S. Stahl and published by John Wiley & Sons. This book was released on 2016-10-10 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book to place recent academic developments within the context of real life industrial applications, this is a timely overview of the field of aerobic oxidation reactions in the liquid phase that also illuminates the key challenges that lie ahead. As such, it covers both homogeneous as well as heterogeneous chemocatalysis and biocatalysis, along with examples taken from various industries: bulk chemicals and monomers, specialty chemicals, flavors and fragrances, vitamins, and pharmaceuticals. One chapter is devoted to reactor concepts and engineering aspects of these methods, while another deals with the relevance of aerobic oxidation catalysis for the conversion of renewable feedstock. With chapters written by a team of academic and industrial researchers, this is a valuable reference for synthetic and catalytic chemists at universities as well as those working in the pharmaceutical and fine chemical industries seeking a better understanding of these reactions and how to design large scale processes based on this technology.
Book Synopsis Insight Into the Oxygen Activation Mechanism by Rieske Dioxygenases Through Kinetic, Spectroscopic and Mutagenesis Studies by : Sarmistha Chakrabarty
Download or read book Insight Into the Oxygen Activation Mechanism by Rieske Dioxygenases Through Kinetic, Spectroscopic and Mutagenesis Studies written by Sarmistha Chakrabarty and published by . This book was released on 2010 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt:
