Molecular Mechanisms of Inflammation: Induction, Resolution and Escape by Helicobacter pylori

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Publisher : Springer
ISBN 13 : 3030151387
Total Pages : 359 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Molecular Mechanisms of Inflammation: Induction, Resolution and Escape by Helicobacter pylori by : Steffen Backert

Download or read book Molecular Mechanisms of Inflammation: Induction, Resolution and Escape by Helicobacter pylori written by Steffen Backert and published by Springer. This book was released on 2019-05-23 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on immune reactions and interactions of humans with Helicobacter pylori - a human pathogen connected to gastritis, peptic ulcers and even gastric cancer. With nearly half of the world’s population colonized, it has been characterized as one of the most successful pathogens for more than 100,000 years of co-evolution with its host. The respective chapters discuss not only how H. pylori infection is considered a paradigm for persistent bacterial infection and chronic inflammation, but also how the infection might be connected to host protection against gastro-esophageal diseases, asthma, and other allergic disease manifestations. Readers will gain essential insights into the roles of specific factors in the immune response and learn about the impact of genetic polymorphisms on the risk of gastric carcinogenesis. In addition, the book discusses the strategies used by this bacterium, which allow it to colonize specific sites in the stomach, interact with the microbiome, evade immune surveillance and undermine the resolution of inflammation during persistent infection. This volume presents a concise summary of recent advances in the areas of induction, resolution and escape of inflammation, innate and adaptive immunity, gastric disease development, as well as treatment and vaccination against H. pylori. Accordingly, it offers a valuable asset for scientists and clinicians alike.

Helicobacter pylori Infection

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Publisher : BoD – Books on Demand
ISBN 13 : 1837681708
Total Pages : 126 pages
Book Rating : 4.8/5 (376 download)

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Book Synopsis Helicobacter pylori Infection by : Daniela Lazar

Download or read book Helicobacter pylori Infection written by Daniela Lazar and published by BoD – Books on Demand. This book was released on 2024-06-12 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents a comprehensive effort to investigate the complexity of Helicobacter pylori infection. As editors and contributors, we aim to provide a thorough exploration of the pathogenesis, diagnostic approaches, and contemporary clinical strategies in managing H. pylori-associated diseases. This book takes us through the multifaceted world of H. pylori infection. The first section provides thorough insights into the most recent knowledge of the pathogenesis, virulence factors, and complex adaptive modalities of H. pylori that allow it to colonize the stomach, evade our immune defenses, and trigger inflammation. This book’s forefront lies in the evolution of diagnosis and clinical management. The book presents modern indications and treatment regimens for H. pylori infection, taking on the emerging challenges posed by antibiotic resistance and exploring the promise of future therapeutic strategies. An increasing number of investigations suggest that H. pylori infection might be involved in many extra gastric disorders such as cardiovascular, metabolic, neurological, dermatological, hematologic, ophthalmic, hepatobiliary, or even allergic diseases. The second section of our book provides the latest information on the potential role of this bacterium in different extra gastric conditions. Doctors of all specialties should take into consideration the possible presence and implications of H. pylori infection. This book is more than just a scientific treatise, it is a testimony to the enduring quest for knowledge and the impact it has on human health. It is addressed to a diverse audience, including healthcare professionals, researchers, students, and individuals intrigued by the fascinating world of microbes and their influence on our well-being. As you turn the pages, prepare to unravel the mysteries of H. pylori infection. This book will equip you with the latest knowledge, ignite your curiosity, and inspire you to contribute to the ongoing battle against this enigmatic foe. Join us on this journey and let us unlock the secrets of H. pylori together.

Gastritis and Gastric Cancer

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Publisher : BoD – Books on Demand
ISBN 13 : 9533073756
Total Pages : 312 pages
Book Rating : 4.5/5 (33 download)

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Book Synopsis Gastritis and Gastric Cancer by : Paola Tonino

Download or read book Gastritis and Gastric Cancer written by Paola Tonino and published by BoD – Books on Demand. This book was released on 2011-09-15 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive overview of invited contributions on Helicobacter pylori infection in gastritis and gastric carcinogenesis. The first part of the book covers topics related to the pathophysiology of gastric mucosal defense system and gastritis including the gastroprotective function of the mucus, the capsaicin-sensitive afferent nerves and the oxidative stress pathway involved in inflammation, apoptosis and autophagy in H. pylori related gastritis. The next chapters deal with molecular pathogenesis and treatment, which consider the role of neuroendocrine cells in gastric disease, DNA methylation in H. pylori infection, the role of antioxidants and phytotherapy in gastric disease. The final part presents the effects of cancer risk factors associated with H. pylori infection. These chapters discuss the serum pepsinogen test, K-ras mutations, cell kinetics, and H. pylori lipopolysaccharide, as well as the roles of several bacterial genes (cagA, cagT, vacA and dupA) as virulence factors in gastric cancer, and the gastrokine-1 protein in cancer progression.

Inflammation and Cancer

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Publisher : Springer
ISBN 13 : 3034808372
Total Pages : 489 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Inflammation and Cancer by : Bharat B. Aggarwal

Download or read book Inflammation and Cancer written by Bharat B. Aggarwal and published by Springer. This book was released on 2014-05-12 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.

Vascular Responses to Pathogens

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Publisher : Academic Press
ISBN 13 : 0128013257
Total Pages : 254 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Vascular Responses to Pathogens by : Felicity N.E. Gavins

Download or read book Vascular Responses to Pathogens written by Felicity N.E. Gavins and published by Academic Press. This book was released on 2015-10-31 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vascular Responses to Pathogens focuses on the growing research from leaders in the field for both the short and long-term impact of pathogens on the vasculature. It discusses various organisms, including bacteria, parasites, and viruses, and their role in key events leading to vascular disease. Formatted to discuss the topic of the interaction of pathogens with the vascular rather than individual diseases described separately, this reference demonstrates that common mechanisms are at play in many different diseases because they have a similar context, their vasculature. This all-inclusive reference book is a must-have tool for researchers and practicing clinicians in the areas of vascular biology, microvasculature, cardiology, and infectious disease. - Covers a wide spectrum of organisms and provides analysis of pathogens and current therapeutic strategies in the context of their vasculature - Provides detailed perspectives on key components contributing to vascular pathogens from leaders in the field - Interfaces between both vascular biology and microbiology by encompassing information on how pathogens affect both macro and microvasculature - Includes coverage of the clinical aspects of sepsis and current therapeutic strategies and anti-sepsis drugs

Ending the War Metaphor

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Publisher : National Academies Press
ISBN 13 : 0309096014
Total Pages : 306 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Ending the War Metaphor by : Institute of Medicine

Download or read book Ending the War Metaphor written by Institute of Medicine and published by National Academies Press. This book was released on 2006-07-09 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases have existed longer than us, as long as us, or are relatively newer than us. It may be the case that a disease has existed for many, many years but has only recently begun affecting humans. At the turn of the century the number of deaths caused by infections in the United States had been falling steadily but since the '80s has seen an increase. In the past 30 years alone 37 new pathogens have been identified as human disease threats and 12% of known human pathogens have been classified as either emerging or remerging. Whatever the story, there is currently a "war" on infectious diseases. This war is simply the systematic search for the microbial "cause" of each disease, followed by the development of antimicrobial therapies. The "war" on infectious diseases, however, must be revisited in order to develop a more realistic and detailed picture of the dynamic interactions among and between host organisms and their diverse populations of microbes. Only a fraction of these microbes are pathogens. Thus, in order to explore the crafting of a new metaphor for host-microbe relationships, and to consider how such a new perspective might inform and prioritize biomedical research, the Forum on Microbial Threats of the Institute of Medicine (IOM) convened the workshop, Ending the War Metaphor: The Changing Agenda for Unraveling the Host-Microbe Relationship on March 16-17, 2005. Workshop participants examined knowledge and approaches to learning about the bacterial inhabitants of the human gut, the best known host-microbe system, as well as findings from studies of microbial communities associated with other mammals, fish, plants, soil, and insects. The perspective adopted by this workshop is one that recognizes the breadth and diversity of host-microbe relationships beyond those relative few that result in overt disease. Included in this summary are the reports and papers of individuals participating in the Forum as well as the views of the editors.

Molecular Mechanisms of Pathogen-Driven Infectious and Neoplastic Diseases

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Publisher : Frontiers Media SA
ISBN 13 : 2889710661
Total Pages : 214 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Molecular Mechanisms of Pathogen-Driven Infectious and Neoplastic Diseases by : Giulia De Falco

Download or read book Molecular Mechanisms of Pathogen-Driven Infectious and Neoplastic Diseases written by Giulia De Falco and published by Frontiers Media SA. This book was released on 2021-07-21 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Epidemiology

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Publisher : Academic Press
ISBN 13 : 0323138578
Total Pages : 609 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Molecular Epidemiology by : Paul A. Schulte

Download or read book Molecular Epidemiology written by Paul A. Schulte and published by Academic Press. This book was released on 2012-12-02 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will serve as a primer for both laboratory and field scientists who are shaping the emerging field of molecular epidemiology. Molecular epidemiology utilizes the same paradigm as traditional epidemiology but uses biological markers to identify exposure, disease or susceptibility. Schulte and Perera present the epidemiologic methods pertinent to biological markers. The book is also designed to enumerate the considerations necessary for valid field research and provide a resource on the salient and subtle features of biological indicators.

Molecular Pathogenesis and Signal Transduction by Helicobacter pylori

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Author :
Publisher : Springer
ISBN 13 : 3319505203
Total Pages : 364 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Molecular Pathogenesis and Signal Transduction by Helicobacter pylori by : Nicole Tegtmeyer

Download or read book Molecular Pathogenesis and Signal Transduction by Helicobacter pylori written by Nicole Tegtmeyer and published by Springer. This book was released on 2017-01-23 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume reviews the current state of research concerning bacterial virulence factors and the infection biology of Helicobacter pylori, which is the leading cause of peptic ulcers and gastric cancer worldwide. The chapters include cutting-edge findings on this fascinating microbe and discuss the general strategies of H. pylori infection and persistence, news on important H. pylori virulence factors, crosstalk with the microbiota, hot novel models and signaling mechanisms, risk factors of gastric disease and stomach cancer, and the impact of H. pylori infection on non-gastric diseases. Written by internationally respected scientists, this book will appeal to clinicians, researchers and advanced students alike.

Bioinorganic Photochemistry

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Publisher : John Wiley & Sons
ISBN 13 : 9781405193276
Total Pages : 398 pages
Book Rating : 4.1/5 (932 download)

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Book Synopsis Bioinorganic Photochemistry by : Grazyna Stochel

Download or read book Bioinorganic Photochemistry written by Grazyna Stochel and published by John Wiley & Sons. This book was released on 2009-06-10 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinorganic photochemistry is a rapidly evolving field integrating inorganic photochemistry with biological, medical and environmental sciences. The interactions of light with inorganic species in natural systems, and the applications in artificial systems of medical or environmental importance, form the basis of this challenging inter-disciplinary research area. Bioinorganic Photochemistry provides a comprehensive overview of the concepts and reactions fundamental to the field, illustrating important applications in biological, medical and environmental sciences. Topics covered include: Cosmic and environmental photochemistry Photochemistry of biologically relevant nanoassemblies Molecular aspects of photosynthesis Photoinduced electron transfer in biosystems Modern therapeutic strategies in photomedicine The book concludes with an outlook for the future of environmental protection, discussing emerging techniques in the field of pollution abatement, and the potential for bioinorganic photochemistry as a pathway to developing cheap, environmentally friendly sources of energy. Written as an authoritative guide for researchers involved in the development of bioinorganic photochemical processes, Bioinorganic Photochemistry is also accessible to scientists new to the field, and will be a key reference source for advanced courses in inorganic, and bioinorganic chemistry.

Immunology and Evolution of Infectious Disease

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Publisher : Princeton University Press
ISBN 13 : 9780691095950
Total Pages : 364 pages
Book Rating : 4.0/5 (959 download)

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Book Synopsis Immunology and Evolution of Infectious Disease by : Steven A. Frank

Download or read book Immunology and Evolution of Infectious Disease written by Steven A. Frank and published by Princeton University Press. This book was released on 2002-07-21 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher Description

Pathogenesis of Shigellosis

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Publisher : Springer Science & Business Media
ISBN 13 : 3642772382
Total Pages : 151 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Pathogenesis of Shigellosis by : P.J. Sansonetti

Download or read book Pathogenesis of Shigellosis written by P.J. Sansonetti and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shigellosis is present all over the world. Anyone traveling in developing countries knows that the control of this invasive disease of the intestine is a priority task for physicians and public health authorities. Victims are essentially young children, and complications such as the hemolytic uremic syndrome make shigellosis a systemic disease rather than simply an infection of the colonic mucosa. However, "Westerners" should not consider shigeJlosis as an unlikely threat of the tropics. The disease arises in industrialized countries as soon as breaches in sanitation appear. A few months ago, at least 500 people developed shigellosis in northern France in an outbreak of Shigella sonnei infection due to accidental contamination of an urban water delivery system. The pathogenesis of shigellosis is an extraordinary topic of research because study of the invasion of the colonic mucosa addresses fundamental questions on. the molecular and cellular mechanisms by which a bacterial pathogen can pene trate non phagocytic cells, survive, multiply, spread in the intra cellular compartment, and eventually kill host cells. Further development of the infection within subepithelial tissues as well as the mechanisms that contribute to the eradication of this process have barely been studied.

The Immune Response

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Publisher : Academic Press
ISBN 13 : 0080534481
Total Pages : 1217 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis The Immune Response by : Tak W. Mak

Download or read book The Immune Response written by Tak W. Mak and published by Academic Press. This book was released on 2005-11-11 with total page 1217 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Immune Response is a unique reference work covering the basic and clinical principles of immunology in a modern and comprehensive fashion. Written in an engaging conversational style, the book conveys the broad scope and fascinating appeal of immunology. The book is beautifully illustrated with superb figures as well as many full color plates. This extraordinary work will be an invaluable resource for lecturers and graduate students in immunology, as well as a vital reference for research scientists and clinicians studying related areas in the life and medical sciences. - Current and thorough 30 chapter reference reviewed by luminaries in the field - Unique 'single voice' ensures consistency of definitions and concepts - Comprehensive and elegant illustrations bring key concepts to life - Provides historical context to allow fuller understanding of key issues - Introductory chapters 1-4 serve as an 'Immunology Primer' before topics are discussed in more detail

The Perfect Slime

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Publisher : IWA Publishing
ISBN 13 : 1780407416
Total Pages : 336 pages
Book Rating : 4.7/5 (84 download)

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Book Synopsis The Perfect Slime by : Hans-Curt Flemming

Download or read book The Perfect Slime written by Hans-Curt Flemming and published by IWA Publishing. This book was released on 2016-09-15 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Perfect Slime presents the latest state of knowledge and all aspects of the Extracellular Polymeric Substances, (EPS) matrix – from the ecological and health to the antifouling perspectives. The book brings together all the current material in order to expand our understanding of the functions, properties and characteristics of the matrix as well as the possibilities to strengthen or weaken it. The EPS matrix represents the immediate environment in which biofilm organisms live. From their point of view, this matrix has paramount advantages. It allows them to stay together for extended periods and form synergistic microconsortia, it retains extracellular enzymes and turns the matrix into an external digestion system and it is a universal recycling yard, it protects them against desiccation, it allows for intense communication and represents a huge genetic archive. They can remodel their matrix, break free and eventually, they can use it as a nutrient source. The EPS matrix can be considered as one of the emergent properties of biofilms and are a major reason for the success of this form of life. Nevertheless, they have been termed the “black matter of biofilms” for good reasons. First of all: the isolation methods define the results. In most cases, only water soluble EPS components are investigated; insoluble ones such as cellulose or amyloids are much less included. In particular in environmental biofilms with many species, it is difficult to impossible isolate, separate the various EPS molecules they are encased in and to define which species produced which EPS. The regulation and the factors which trigger or inhibit EPS production are still very poorly understood. Furthermore: bacteria are not the only microorganisms to produce EPS. Archaea, Fungi and algae can also form EPS. This book investigates the questions, What is their composition, function, dynamics and regulation? What do they all have in common?

Oral Health in America

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Publisher :
ISBN 13 :
Total Pages : 336 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis Oral Health in America by :

Download or read book Oral Health in America written by and published by . This book was released on 2000 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Concepts and Principles of Pharmacology

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Publisher : Springer Nature
ISBN 13 : 3030353621
Total Pages : 466 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Concepts and Principles of Pharmacology by : James E. Barrett

Download or read book Concepts and Principles of Pharmacology written by James E. Barrett and published by Springer Nature. This book was released on 2019-12-24 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Celebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years. These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape discovery of new medicinies. Newly evolving technologies will similarly be discussed as they will shape the future of the pharmacology and, accordingly, medical therapy.

Physics of Cancer

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Publisher : Iph001
ISBN 13 : 9780750317511
Total Pages : 500 pages
Book Rating : 4.3/5 (175 download)

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Book Synopsis Physics of Cancer by : Claudia Mierke

Download or read book Physics of Cancer written by Claudia Mierke and published by Iph001. This book was released on 2018-10-24 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised second edition is improved linguistically with multiple increases of the number of figures and the inclusion of several novel chapters such as actin filaments during matrix invasion, microtubuli during migration and matrix invasion, nuclear deformability during migration and matrix invasion, and the active role of the tumor stroma in regulating cell invasion.