Molecular Diagnosis And Targeting For Gynecologic Malignancy

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Molecular Diagnosis and Targeting for Gynecologic Malignancy

Author : Seiji Isonishi
Publisher : Springer Nature
ISBN 13 : 9813360135
Total Pages : 171 pages
Book Rating : 4.8/5 (133 download)

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Book Synopsis Molecular Diagnosis and Targeting for Gynecologic Malignancy by : Seiji Isonishi

Download or read book Molecular Diagnosis and Targeting for Gynecologic Malignancy written by Seiji Isonishi and published by Springer Nature. This book was released on 2021-03-05 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the important developments in the field of cancer research, specifically uterine cervical/endometrial cancer and ovarian cancer. It highlights the recent advances in gynecologic cancer, such as next generation models of genetically engineered animal models or cancer cell lines, focusing on their significance for advancing our understanding of gynecologic cancer biology, prevention and treatment, and drug response and resistance. Cancer research in the area of gynecologic tumors has undergone an enormous transformation over the past decade, with a greater understanding of tumor biology, elucidation of novel targets for therapeutic intervention, and better recognition of genetic predisposition syndromes. At the same time, the recent advances in basic cancer research have provided key insights into all aspects of gynecologic cancer biology, including developmental pathways and the impact of lineage plasticity, understanding metastatic progression, uncovering the roles of the tumor microenvironment , exploring tumor evolution, and discovering new therapeutic approaches and mechanisms of drug sensitivity and adaptive response. Molecular Diagnosis and Targeting for Gynecologic Malignancy appeals to investigators, clinicians, residents and postdocs who are curious about new research on gynecologic malignancies. It not only presents basic and translational research, but also explores the generalizability of the evidence covering the interface between basic and clinical science. Furthermore, a number of the topics offer the basis for new ideas that have the potential to advance into the gynecologic malignancies. This book provides readers with state-of-the-art information that will help improve the lives of patients with these challenging diseases.

Noninvasive Molecular Markers in Gynecologic Cancers

Author : Debmalya Barh
Publisher : CRC Press
ISBN 13 : 1466569395
Total Pages : 516 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Noninvasive Molecular Markers in Gynecologic Cancers by : Debmalya Barh

Download or read book Noninvasive Molecular Markers in Gynecologic Cancers written by Debmalya Barh and published by CRC Press. This book was released on 2015-01-22 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: Early detection is critical for any given cancer. With the advent of the latest omics technologies, molecular markers in combination with conventional diagnostic and screening methods are emerging as next-generation early diagnostic and prognostic strategies that can allow early-stage diagnosis, resulting in more effective treatment and patient car

Diagnosis and Treatment of Rare Gynecologic Cancers

Author : Michael Frumovitz
Publisher : Elsevier Health Sciences
ISBN 13 : 0323829392
Total Pages : 387 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Diagnosis and Treatment of Rare Gynecologic Cancers by : Michael Frumovitz

Download or read book Diagnosis and Treatment of Rare Gynecologic Cancers written by Michael Frumovitz and published by Elsevier Health Sciences. This book was released on 2022-05-10 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering a one-stop guide to recognition and therapeutic decision making, Diagnosis and Treatment of Rare Gynecologic Cancers fills a gap in the medical literature on uncommon ovarian, uterine, cervical, and vulvovaginal cancers and trophoblastic diseases. This authoritative text, edited by Drs. Michael Frumovitz, Mario Leitao, and Preetha Ramalingam, has been authored by internationally recognized experts from top institutions such as MD Anderson Cancer Center and Memorial Sloan Kettering Cancer Center. Each chapter covers different cancer subtypes and has been reviewed by an oncologist and a pathologist. Provides up-to-date clinical guidance on assessment and therapeutic options for patients with rare gynecologic malignancies. Presents information in a templated, easy-to-read format. Each chapter includes an introductory clinical case followed by epidemiology of disease, pathologic assessment, basic science/molecular/translational research, work-up of newly diagnosed disease, staging, treatment of newly diagnosed disease, treatment of recurrent disease, potential therapeutic targets, and a case resolution. Includes diagnostic and treatment algorithms for each form of cancer. Contains numerous anatomical figures, radiographs, photographs, and tables for quick visual reference.

Gynecological Cancers

Author : Antonio Giordano
Publisher : Springer
ISBN 13 : 3319329073
Total Pages : 176 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Gynecological Cancers by : Antonio Giordano

Download or read book Gynecological Cancers written by Antonio Giordano and published by Springer. This book was released on 2016-07-12 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: Facilitating the collaboration between the basic, translational, and clinical sciences, this book provides an overview of the genetic and epigenetic mechanisms underlying the formation and progression of gynecological cancers. Gynecological Cancers: Genetic and Epigenetic Targets and Drug Development gathers all of the molecular and cellular aspects of gynecological cancer together within one volume, providing detailed and up-to-date information on the etiology, diagnosis, and treatment of gynecological cancers. Gynecological Cancers: Genetic and Epigenetic Targets and Drug Development also discusses the racial and ethnic disparities in the treatment of gynecological cancers through cost effective modalities like single visit screening and diagnosis, well women clinics, and mobile clinics. Written and edited by leaders in the field, this volume within the Current Clinical Oncology series is an indispensable resource for today’s practicing oncologist.

Gynecologic Cancers

Author : Kunle Odunsi, MD
Publisher : Demos Medical Publishing
ISBN 13 : 1617051519
Total Pages : 315 pages
Book Rating : 4.6/5 (17 download)

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Book Synopsis Gynecologic Cancers by : Kunle Odunsi, MD

Download or read book Gynecologic Cancers written by Kunle Odunsi, MD and published by Demos Medical Publishing. This book was released on 2013-10-09 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the course of the last decade, the treatment of gynecologic cancer has evolved quite rapidly. New scientific and clinical advances have modified the standard of care and led to improved patient outcomes. At the same time, the treatment of gynecologic cancer has become increasingly complex, requiring the comprehensive review and assessment of multiple issues including genetics, radiology, surgery, molecular diagnostics, chemotherapy, and more. As a result, the harmony and open communication between these specialties facilitated by a multidisciplinary team approach are crucial in providing the best care to patients and ensuring successful treatment. Gynecologic Cancers: A Multidisciplinary Approach to Diagnosis and Management, written by a multidisciplinary team of authors representing a range of disciplines, is a valuable resource for physicians, fellows, nurses, physician assistants, physical therapists, and all health care providers involved in the treatment of gynecologic cancer. Gynecologic Cancers: A Multidisciplinary Approach to Diagnosis and Management summarizes the state-of-the-art issues related to the treatment of gynecologic cancer and describes an approach for optimal multidisciplinary care for women who have been diagnosed with or who are at higher risk to develop gynecologic cancer. About the Series: The Current Multidisciplinary Oncology series, edited by Charles R. Thomas, consolidates and integrates the varied aspects of multidisciplinary care for major topics in oncology, including breast, lung, prostrate, head and neck and more. The volumes in the Current Multidisciplinary Oncology series represent all related topic areas, including oncology, radiation oncology, pain, pathology, imaging, psychological support and the primary disease. In addition, each volume includes a chapter focusing on special populations and the disease's impact / difference on them, and discussion of future directions and quality of life issues. In addition each volume has a chapter written by a private practice oncologist. All Current Multidisciplinary Oncology titles provide: Consolidation and integration of the varied aspects of multidisciplinary care for major topics in oncology Coverage of all related topic areas, including medical and surgical oncology, radiation oncology, pain, pathology, imaging, psychological support, and the primary disease A chapter focusing on special populations and the disease's differing impact on them Discussion of quality-of-life issues

Molecular Diagnosis of Cancer

Author : Joseph E. Roulston
Publisher : Springer Science & Business Media
ISBN 13 : 1592597602
Total Pages : 389 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Molecular Diagnosis of Cancer by : Joseph E. Roulston

Download or read book Molecular Diagnosis of Cancer written by Joseph E. Roulston and published by Springer Science & Business Media. This book was released on 2008-02-01 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: We are currently experiencing a fundamental shift in the way in which we approach the characterization of cancer. Never before has the make up of cancer tissues and individual cells been so exhaustively researched and char- terized. We are now capable of producing molecular “fingerprints” that ch- acterize the expression of all known and unknown genes within tumors and their surrounding tissues. More than 30,000 different genes may be measured in each patient’s tumor in a single experiment. Simultaneously, novel therapies that exploit the molecular roadmap have been developed and are now being offered to patients. These novel agents, such as Glivec, Herceptin, Iressa, and others, specifically target individual genes within tumors and can produce d- matic responses in some patients. These drugs are only the forerunners of a coming tidal wave of novel therapeutics that individually target specific m- ecules within cancer cells—more than 300 such agents are currently in phase I or II clinical trials. This is an exciting time for cancer specialists and patients alike. However, if we have learned anything from the past 50 or more years of research into cancer, it is that Lord Beaverbrook, in founding the British national health service in the 1950s, was frighteningly prescient when he defined the primary goal of health care to be “Diagnosis, Diagnosis, Diag- sis. ” Now, more than ever, it is essential that appropriate diagnostic methods and approaches are applied to the selection of patients for treatment.

Principles and Practice of Gynecologic Oncology

Author : Dennis S. Chi
Publisher : LWW
ISBN 13 : 9781496340023
Total Pages : 0 pages
Book Rating : 4.3/5 (4 download)

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Book Synopsis Principles and Practice of Gynecologic Oncology by : Dennis S. Chi

Download or read book Principles and Practice of Gynecologic Oncology written by Dennis S. Chi and published by LWW. This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sect. I: Etiology, prevention, and molecular biology -- Epidemiology of gynecologic cancers -- Molecular pathogenesis of gynecologic cancers -- Hereditary gynecologic cancers -- Invasion, metastasis, and angiogenesis -- Development and identification of tumor serum markers -- Cancer prevention strategies -- Preinvasive disease of the lower genital tract -- Sect. II: Diagnostic and therapeutic modalities -- Perioperative and critical care -- Surgical principles in gynecologic oncology -- Diagnostic imaging -- Biologic and physical principles of radiation oncology -- Targeted therapies in gynecologic cancers -- Principles of chemotherapy in gynecologic cancer -- Pharmacology and therapeutics in gynecologic cancer -- Immunotherapy of gynecologic malignancies -- Clinical trials methodology and biostatistics -- Cost-effective and value-based gynecologic cancer care -- Sect. III: Disease sites -- Vulva -- Vaginal cancer -- Cervix uteri -- Corpus: epithelial tumors -- Corpus: mesenchymal tumors -- Epithelial ovarian cancer -- Overian germ cell tumors -- Overian sex cord-stromal tumors -- Gestational trophoblastic disease: molar pregnancy and gestational trophoblastic neoplasia -- Sect. IV: Special management topics -- Breast cancer -- Management of infection in patients with gynecologic malignancy -- Management of surgical complications of gynecologic cancer treatment -- Management of pain -- Nutrition support of patients with gynecologic cancer -- Palliative and supportive care

Ovarian Cancers

Author : Eric Pujade-Lauraine
Publisher : Springer
ISBN 13 : 3319321102
Total Pages : 288 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Ovarian Cancers by : Eric Pujade-Lauraine

Download or read book Ovarian Cancers written by Eric Pujade-Lauraine and published by Springer. This book was released on 2016-10-17 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of the latest developments in the concepts and management of ovarian cancer. The new data presented throughout opens the way to radically different therapeutic approaches. Surgery remains the core of ovarian cancer treatment, but its ultimate goal and the standard surgical procedure have evolved, giving rise to the question of how to label expert centers for debulking surgery. Neo-adjuvant chemotherapy is becoming more popular and is also a new field for testing novel drug combinations. Over recent years, ovarian cancer management has embraced molecular biology. It is now more correct to talk about cancers of the ovary rather than ovarian cancer, since it is not a unique disease but several entities with different molecular drivers. The significant advances in drugs targeting the microenvironment or the tumor cell DNA repair mechanisms are presented in detail together with exciting future perspectives. All these advances would not have been possible without collaborative groups such as the GINECO group in France and their integration in wider clinical research networks at the European (ENGOT) and international (GCIG) level.

Ovarian Cancer Biomarkers

Author : Khalid El Bairi
Publisher : Springer Nature
ISBN 13 : 9811618739
Total Pages : 236 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Ovarian Cancer Biomarkers by : Khalid El Bairi

Download or read book Ovarian Cancer Biomarkers written by Khalid El Bairi and published by Springer Nature. This book was released on 2021-10-09 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively summarizes the biology, etiology, and pathology of ovarian cancer and explores the role of deep molecular and cellular profiling in the advancement of precision medicine. The initial chapter discusses our current understanding of the origin, development, progression and tumorigenesis of ovarian cancer. In turn, the book highlights the development of resistance, disease occurrence, and poor prognosis that are the hallmarks of ovarian cancer. The book then reviews the role of deep molecular and cellular profiling to overcome challenges that are associated with the treatment of ovarian cancer. It explores the use of genome-wide association analysis to identify genetic variants for the evaluation of ovarian carcinoma risk and prognostic prediction. Lastly, it highlights various diagnostic and prognostic ovarian cancer biomarkers for the development of molecular-targeted therapy.

Gynecologic Oncology Handbook

Author : Michelle F. Benoit, MD
Publisher : Springer Publishing Company
ISBN 13 : 0826155987
Total Pages : 595 pages
Book Rating : 4.8/5 (261 download)

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Book Synopsis Gynecologic Oncology Handbook by : Michelle F. Benoit, MD

Download or read book Gynecologic Oncology Handbook written by Michelle F. Benoit, MD and published by Springer Publishing Company. This book was released on 2023-01-20 with total page 595 pages. Available in PDF, EPUB and Kindle. Book excerpt: Known as the “blue book”, the Gynecologic Oncology Handbook: An Evidence-Based Clinical Guide is an invaluable resource for fellows, residents, and clinicians in the diagnosis and management of gynecologic cancers. Retaining the format and features that have made it a leading practical reference, this new edition has been thoroughly updated and reflects the latest advances in surgical techniques, chemotherapy protocols, breakthroughs in immunotherapies and targeted therapies, and much more. The handbook covers the full scope of disease management in a concise and accessible format. Its compact size allows it to be easily taken with the busy practitioner on the ward or in the clinic. Clear illustrations that reinforce key concepts and essential algorithms for diagnostic techniques help clinicians to a quick and accurate diagnosis. Evidence-based practices for managing gynecologic cancers are emphasized throughout the handbook including for surgical care, and for all adjuvant therapies including chemotherapy, biologics, targeted therapies, immunotherapies, and combination radiation therapy. Detailed sections on survivorship care, palliative care, and management of reproductive function and other comorbid medical conditions round out the book’s comprehensive scope. Its extensive coverage of current breakthroughs in treatment, references to critical clinical studies, and breakdown of directed gynecologic cancer workups and treatments make the Gynecologic Oncology Handbook, 3rd Edition a go-to resource within the field—including in preparation for the gynecologic oncology subspecialty certification oral board exam. Key Features: Covers all fundamentals of gynecologic oncology including workup, AJCC and FIGO staging, surgical management, chemotherapy, targeted therapy, immunotherapy, and radiation therapy treatment, comorbidity diagnosis and management, and background study data Contains insight into recently approved immunotherapies for recurrent advanced and metastatic cervical and uterine disease Provides Gynecologic Oncology Referral Parameters, Performance Status Scales, Adverse Event Grading, RECIST evaluation criteria, chemotherapy protocols, statistics, and other useful formulas Includes clinical study references, medical comorbidity algorithms, directed workups, and treatment guidelines

Translational Advances in Gynecologic Cancers

Author : Michael Birrer
Publisher : Academic Press
ISBN 13 : 0128037989
Total Pages : 356 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Translational Advances in Gynecologic Cancers by : Michael Birrer

Download or read book Translational Advances in Gynecologic Cancers written by Michael Birrer and published by Academic Press. This book was released on 2017-01-25 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Advances in Gynecologic Cancers straddles the bench and bed divide by highlighting important and interesting research that is translatable to the clinic. The contents of this book cover the entire spectrum, from promising laboratory based research, to clinical trial efforts. Further, new therapeutic indications based upon randomized phase III trials are also included. Clinicians will learn about lab-based science that is about to enter the clinic, along with the rationale behind translational endpoints in trials. Researchers will be able to identify and understand the clinical needs of patients with these types of tumors to improve their research focus. Provides a comprehensive description of all evolving translational gynecologic cancer research for clinicians Identifies knowledge gaps to inform the next research direction Ties together clinical research and patient needs to help both the researcher and clinician Addresses genomics, new target therapies, novel tools, and more for ovarian, endometrial, and cervical cancer

Management of Endometrial Cancer

Author : Mansoor R. Mirza
Publisher : Springer
ISBN 13 : 3319645137
Total Pages : 324 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Management of Endometrial Cancer by : Mansoor R. Mirza

Download or read book Management of Endometrial Cancer written by Mansoor R. Mirza and published by Springer. This book was released on 2019-08-26 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical reference book provides up-to-date, evidence-based multidisciplinary guidelines on the epidemiology, biology, diagnosis, and treatment of endometrial cancer. Individual chapters focus on topics such as hormonal interactions, cancer prevention, genetic classification and its clinical applications. Recent advances in diagnostic methods are described. The treatment-oriented chapters include coverage of the roles of lymphadenectomy and sentinel node dissection, surgical complications, radiation techniques, and chemotherapy in early-stage disease. Treatment options in advanced disease, including hormonal therapy and targeted therapy, are considered separately, as is the management of rare tumor types. The authors are international key opinion leaders. Summaries of the ESMO/ESGO/ESTRO guidelines on management are included. Each clinical chapter ends with a summary of recommendations with the level of evidence.

Ovarian Cancers

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309380499
Total Pages : 397 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Ovarian Cancers by : National Academies of Sciences, Engineering, and Medicine

Download or read book Ovarian Cancers written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-04-25 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: In an era of promising advances in cancer research, there are considerable and even alarming gaps in the fundamental knowledge and understanding of ovarian cancer. Researchers now know that ovarian cancer is not a single disease-several distinct subtypes exist with different origins, risk factors, genetic mutations, biological behaviors, and prognoses. However, persistent questions have impeded progress toward improving the prevention, early detection, treatment, and management of ovarian cancers. Failure to significantly improve morbidity and mortality during the past several decades is likely due to several factors, including the lack of research being performed by specific disease subtype, lack of definitive knowledge of the cell of origin and disease progression, and incomplete understanding of genetic and non-genetic risk factors. Ovarian Cancers examines the state of the science in ovarian cancer research, identifies key gaps in the evidence base and the challenges to addressing those gaps, considers opportunities for advancing ovarian cancer research, and examines avenues for translation and dissemination of new findings and communication of new information to patients and others. This study makes recommendations for public- and private-sector efforts that could facilitate progress in reducing the incidence of morbidity and mortality from ovarian cancers.

Endometrial Cancer: Current Epidemiology, Detection and Management (Second Edition)

Author : Samir A. Farghaly
Publisher : Nova Medicine & Health
ISBN 13 : 9781685079642
Total Pages : 0 pages
Book Rating : 4.0/5 (796 download)

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Book Synopsis Endometrial Cancer: Current Epidemiology, Detection and Management (Second Edition) by : Samir A. Farghaly

Download or read book Endometrial Cancer: Current Epidemiology, Detection and Management (Second Edition) written by Samir A. Farghaly and published by Nova Medicine & Health. This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The purpose of this book is to provide a broad background of several aspects of basic sciences, clinical, therapeutic aspects, and management of endometrial cancer. It provides state-of-the-art information on the molecular genetics, biology, and clinical aspects of premalignant lesions of the endometrium and endometrial cancer. Also, the book chapters provide better understanding of the molecular and cellular events that underlie endometrial cancer. The descriptive and analytical epidemiology of endometrial cancer are presented in Chapter 1. The pathology and molecular diagnosis of endometrial cancer are discussed in Chapter 2. The molecular pathology of endometrial cancer is detailed in Chapter 3. The hereditary aspect of endometrial cancer is highlighted in Chapter 4. Precancerous lesions of the endometrium are reviewed in detail in Chapter 5. Endometrial biomarkers are detailed in Chapter 6. Lymphatic mapping of endometrial cancer is discussed in Chapter 7. Sentinel lymph nodes in endometrial cancer are highlighted in Chapter 8. The current strategies and approaches to treat patients with endometrial cancer are detailed in Chapter 9. Surgical techniques for endometrial cancer are reviewed in Chapter 10. The current treatment of advanced endometrial cancer is discussed in Chapter 11. Adjuvant medical therapeutic modalities are reviewed in Chapter 12. Targeted therapies for advanced endometrial cancer are presented in Chapter 13. The role of ErbB targeted therapy in treating endometrial cancer is discussed in Chapter 14. Finally, the quality of life of women with endometrial cancer is reviewed in Chapter 15. This book is intended for all clinicians and basic medical scientists caring for women with endometrial cancer, including attending surgeons and physicians, clinical fellows, and residents in the disciplines of gynecologic oncology, medical oncology, and surgical oncology, as well as PhD students and post-doctoral fellows in the basic medical sciences"--

Clinical Gynecologic Oncology E-Book

Author : Philip J. DiSaia
Publisher : Elsevier Health Sciences
ISBN 13 : 0323443168
Total Pages : 893 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Clinical Gynecologic Oncology E-Book by : Philip J. DiSaia

Download or read book Clinical Gynecologic Oncology E-Book written by Philip J. DiSaia and published by Elsevier Health Sciences. This book was released on 2017-02-04 with total page 893 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most readable, most comprehensive book in its field, Clinical Gynecologic Oncology, 9th Edition is the leading reference for diagnosis and treatment of gynecologic cancers – a must-have reference for improving outcomes and providing effective care. A "who’s who" list of contributing authors, under the editorial direction of Drs. Philip DiSaia and William Creasman, provides expert guidance on clinical presentations and management, now fully up to date with a brand-new design for faster, easier reference. Contains useful appendices covering staging, screening, nutritional therapy, toxicity criteria, blood component therapy, and radiation therapy. Covers hot topics such as multi-panel genetic testing, target therapies, sentinel node concept in endometrial cancer and vulvar cancer, and robotic surgery. Updates include new quick-reference features such as key point boxes with bulleted lists, highlighted key text, enhanced chapter outlines, and a brand-new design throughout. Includes up-to-date references and algorithms, making this text a comprehensive resource for clinical practice, personal study, and exam review. Helps you take advantage of the latest advances in early detection and improved treatment options for gynecologic cancers, especially uterine and cervical cancers.

Principles of Molecular Diagnostics and Personalized Cancer Medicine

Author : Dongfeng Tan
Publisher : LWW
ISBN 13 : 9781451131970
Total Pages : 0 pages
Book Rating : 4.1/5 (319 download)

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Book Synopsis Principles of Molecular Diagnostics and Personalized Cancer Medicine by : Dongfeng Tan

Download or read book Principles of Molecular Diagnostics and Personalized Cancer Medicine written by Dongfeng Tan and published by LWW. This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Molecular Diagnostics and Personalized Cancer Medicine The role of molecular genetics in the treatment of malignancy continues to grow at an astonishing rate. Today's subspecialized multidisciplinary approach to oncology has incorporated advances in targeted molecular therapy, prognosis, risk assessment, and prevention--all based at least in part on molecular diagnostics and imaging. Inside this cutting-edge resource, readers will explore broad, comprehensive perspectives on the current trends in molecular diagnosis of cancer and personalized cancer medicine. Authoritative discussions share insights from noted experts in cancer research, clinical trials, molecular diagnostics, personalized therapy, bioinformatics, and federal regulations. From the basic mechanisms of carcinogenesis to the most advanced molecular screening, staging, and treatment technologies, readers will discover clear and straightforward discussions directly relevant to patient diagnosis and care. Improve your understanding of... - The basic mechanisms of carcinogenesis-- including material on cell proliferation, signal transduction pathways, cancer stem cells, and the interaction between genetics and environmental factors. - The most current molecular techniques --including polymerase chain reaction (PCR) technique, single nucleotide polymorphisms, cancer cytogenomics and epigenetics, whole-genome assessments, and next- generation sequencing. - Molecular tests --including molecular screening, minimal residual disease detection, circulating tumor cell tests, molecular tumor staging, and molecular cancer prognosis assessment. - Imaging and screening technologies --including molecular imaging, genetic tests, biostatistics, and bioinformatics. - The molecular basis of therapy --including critical molecules as special treatment targets, particularly genes/DNA, RNA, micro RNAs, proteins/antibodies, and nanoparticles. - Molecular diagnostics - including updated molecular diagnostic approaches to common malignancies and role of pathology in targeted cancer management. - Targeted treatment - including personalized medicine and targeted therapy for commonly occurring malignancies-- plus insights on new approaches to targeted drug discovery and the future of molecular oncology!

Recent Advances in Endometrial Cancer

Author : Sumita Mehta
Publisher : Springer Nature
ISBN 13 : 9811553173
Total Pages : 306 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Recent Advances in Endometrial Cancer by : Sumita Mehta

Download or read book Recent Advances in Endometrial Cancer written by Sumita Mehta and published by Springer Nature. This book was released on 2020-07-23 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses in detail the recent advances in the management of endometrial cancer, including the latest therapies and diagnostic methods. The book focuses on treatment-oriented topics such as the role of lymphadenectomy and sentinel node dissection, surgical complications, radiation techniques, and chemotherapy in endometrial cancer, and also explores treatment options in advanced disease stages, including hormonal therapy and targeted therapy. Providing insights into the evidence-based management guidelines for endometrial cancer, this book is a valuable resource for students, trainees and practitioners in the field of gynecology and gyne-oncology.