Molecular Considerations and Evolving Surgical Management Issues in the Treatment of Patients with a Brain Tumor

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 953512031X
Total Pages : 436 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Molecular Considerations and Evolving Surgical Management Issues in the Treatment of Patients with a Brain Tumor by : Terry Lichtor

Download or read book Molecular Considerations and Evolving Surgical Management Issues in the Treatment of Patients with a Brain Tumor written by Terry Lichtor and published by BoD – Books on Demand. This book was released on 2015-03-25 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: A dramatic increase in knowledge regarding the molecular biology of brain tumors has been established over the past few years. In particular, recent new avenues regarding the role of microRNAs along with further understanding of the importance of angiogenesis, immunotherapy and explanations for the resistance of the tumors to radiation therapy have been developed. A discussion of certain surgical management issues including improvements in imaging along with issues concerning tumor induced epilepsy is included. It is hopeful that this new information will lead to efficacious treatment strategies for these tumors which remain a challenge. In this book, a review of the latest information on these topics along with a variety of new therapeutic treatment strategies with an emphasis on molecular targeted therapies is provided.

Clinical Management and Evolving Novel Therapeutic Strategies for Patients with Brain Tumors

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9535110586
Total Pages : 656 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Clinical Management and Evolving Novel Therapeutic Strategies for Patients with Brain Tumors by : Terry Lichtor

Download or read book Clinical Management and Evolving Novel Therapeutic Strategies for Patients with Brain Tumors written by Terry Lichtor and published by BoD – Books on Demand. This book was released on 2013-04-10 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: A dramatic increase in knowledge regarding the molecular biology of brain tumors has been established over the past few years, and this has lead to the development of novel therapeutic strategies for these patients. In this book a review of the options available for the clinical management of patients with these tumors are outlined. In addition advances in radiology both for pre-operative diagnostic purposes along with surgical planning are described. Furthermore a review of newer developments in chemotherapy along with the evolving field of photodynamic therapy both for intra-operative management and subsequent therapy is provided. A discussion of certain surgical management issues along with tumor induced epilepsy is included. Finally a discussion of the management of certain unique problems including brain metastases, brainstem glioma, central nervous system lymphoma along with issues involving patients with a brain tumor and pregnancy is provided.

Evolution of the Molecular Biology of Brain Tumors and the Therapeutic Implications

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Publisher : BoD – Books on Demand
ISBN 13 : 9535109898
Total Pages : 652 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Evolution of the Molecular Biology of Brain Tumors and the Therapeutic Implications by : Terry Lichtor

Download or read book Evolution of the Molecular Biology of Brain Tumors and the Therapeutic Implications written by Terry Lichtor and published by BoD – Books on Demand. This book was released on 2013-02-27 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: A dramatic increase in knowledge regarding the molecular biology of brain tumors has been established over the past few years. In particular recent new avenues regarding the role of stem cells and microRNAs along with further understanding of the importance of angiogenesis, immunotherapy and explanations for the resistance of the tumors to chemotherapeutic agents and radiation therapy has been developed. It is hopeful that this new information will lead to efficacious treatment strategies for these tumors which remain a challenge. In this book a review of the latest information on these topics along with a variety of new therapeutic treatment strategies with an emphasis on molecular targeted therapies is provided.

Clinical Management and Evolving Novel Therapeutic Strategies for Patients with Brain Tumors

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Author :
Publisher : IntechOpen
ISBN 13 : 9789535110583
Total Pages : 654 pages
Book Rating : 4.1/5 (15 download)

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Book Synopsis Clinical Management and Evolving Novel Therapeutic Strategies for Patients with Brain Tumors by : Terry Lichtor

Download or read book Clinical Management and Evolving Novel Therapeutic Strategies for Patients with Brain Tumors written by Terry Lichtor and published by IntechOpen. This book was released on 2013-04-10 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: A dramatic increase in knowledge regarding the molecular biology of brain tumors has been established over the past few years, and this has lead to the development of novel therapeutic strategies for these patients. In this book a review of the options available for the clinical management of patients with these tumors are outlined. In addition advances in radiology both for pre-operative diagnostic purposes along with surgical planning are described. Furthermore a review of newer developments in chemotherapy along with the evolving field of photodynamic therapy both for intra-operative management and subsequent therapy is provided. A discussion of certain surgical management issues along with tumor induced epilepsy is included. Finally a discussion of the management of certain unique problems including brain metastases, brainstem glioma, central nervous system lymphoma along with issues involving patients with a brain tumor and pregnancy is provided.

Glioblastoma, Part I: Surgical Management and Adjuncts, An Issue of Neurosurgery Clinics of North America, E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 032379095X
Total Pages : 169 pages
Book Rating : 4.3/5 (237 download)

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Book Synopsis Glioblastoma, Part I: Surgical Management and Adjuncts, An Issue of Neurosurgery Clinics of North America, E-Book by : Michael A Vogelbaum

Download or read book Glioblastoma, Part I: Surgical Management and Adjuncts, An Issue of Neurosurgery Clinics of North America, E-Book written by Michael A Vogelbaum and published by Elsevier Health Sciences. This book was released on 2020-12-04 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Neurosurgery Clinics, guest edited by Dr. Michael A. Vogelbaum, is devoted to Glioblastoma, Part I: Surgical Management and Adjuncts. This is one of four issues selected each year by the series Consulting Editors, Russell R. Lonser and Daniel K. Resnick. Articles in this issue include: Perioperative Management of Patients with Glioblastoma, Role of Resection in Glioblastoma Management, Advancing Imaging to Enhance Surgery, Intraoperative Imaging for High-Grade Glioma Surgery, Use of Intraoperative Fluorophores, Extent of Resection of Glioblastoma, Functional Mapping for Glioma Surgery: Preoperative Mapping Tools, Functional Mapping for Glioma Surgery: Intraoperative Mapping Tools, Surgical Adjuncts for Glioblastoma, Window of Opportunity Clinical Trials to Evaluate Novel Therapies for Brain Tumors, Stereotactic Laser Ablation of Glioblastoma, Radiosurgery for Glioblastoma, Challenges Associated with Reoperation in Patients with Glioma, and Surgery for Glioblastoma in Elderly Patients.

Clinical Management and Evolving Novel Therapeutic Strategies for Patients with Brain Tumors

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Author :
Publisher : IntechOpen
ISBN 13 : 9789535110583
Total Pages : 654 pages
Book Rating : 4.1/5 (15 download)

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Book Synopsis Clinical Management and Evolving Novel Therapeutic Strategies for Patients with Brain Tumors by : Terry Lichtor

Download or read book Clinical Management and Evolving Novel Therapeutic Strategies for Patients with Brain Tumors written by Terry Lichtor and published by IntechOpen. This book was released on 2013-04-10 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: A dramatic increase in knowledge regarding the molecular biology of brain tumors has been established over the past few years, and this has lead to the development of novel therapeutic strategies for these patients. In this book a review of the options available for the clinical management of patients with these tumors are outlined. In addition advances in radiology both for pre-operative diagnostic purposes along with surgical planning are described. Furthermore a review of newer developments in chemotherapy along with the evolving field of photodynamic therapy both for intra-operative management and subsequent therapy is provided. A discussion of certain surgical management issues along with tumor induced epilepsy is included. Finally a discussion of the management of certain unique problems including brain metastases, brainstem glioma, central nervous system lymphoma along with issues involving patients with a brain tumor and pregnancy is provided.

Glioblastoma, Part II: Molecular Targets and Clinical Trials, An Issue of Neurosurgery Clinics of North America

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323813062
Total Pages : 208 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Glioblastoma, Part II: Molecular Targets and Clinical Trials, An Issue of Neurosurgery Clinics of North America by : Linda M. Liau

Download or read book Glioblastoma, Part II: Molecular Targets and Clinical Trials, An Issue of Neurosurgery Clinics of North America written by Linda M. Liau and published by Elsevier Health Sciences. This book was released on 2021-04-08 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Neurosurgery Clinics, guest edited by Dr. Linda M. Liau, is dedicated to Glioblastoma: Molecular and Clinical Trials. This issue is one of four selected each year by the series consulting editors, Drs. Russell R. Lonser and Daniel K. Resnick. Topics will include—but are not limited to—Pathology & Molecular Markers, Cellular States & Genetic Diversity in Glioblastoma, Mismatch Repair in Glioblastoma Resistance, Genetic Susceptibility in Brain Cancer, Pediatric Gliomas: Molecular Landscape & Emerging Targets, Molecularly Targeted Clinical Trials, Novel Radiation Sensitizers, Immunotherapy Checkpoint Inhibitors, Brain Tumor Vaccines, CAR T Cells, Oncolytic Virotherapy, Targeting Cancer Stem Cells, Therapeutic Delivery to CNS, Theranostics: Dual Modality PET Tracers, and Neuroimaging & Novel Response Assessments.

Brain Tumor Invasion

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Author :
Publisher : Wiley-Liss
ISBN 13 :
Total Pages : 494 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Brain Tumor Invasion by : Tom Mikkelsen

Download or read book Brain Tumor Invasion written by Tom Mikkelsen and published by Wiley-Liss. This book was released on 1998-05-05 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Tumor Invasion Biological, Clinical, and Therapeutic Considerations Edited by Tom Mikkelsen Rolf Bjerkvig Ole Didrik Laerum Mark L. Rosenblum Recent advances in molecular biology have given us profound new insights into the behavior of primary brain tumors. Not only are such tumors more diffuse in their infiltration of brain tissue and therefore less amenable to surgery than brain tumors originating elsewhere in the body—it now appears that the central nervous system and the normal brain itself constitute a biological environment conducive to the uncontrolled spread of primary tumors. Brain Tumor Invasion is the first comprehensive reference devoted to the invasive behavior of primary brain tumors. It examines the biological mechanisms responsible for the increased ability of gliomas to metastasize in the central nervous system, and discusses the role of chemical carcinogens, growth factors, oncogenes, and tumor suppressors in the progression of such metastases. This book surveys the latest research in the field, reviews present and future prospects of anti-invasive brain tumor therapy, and even translates preclinical trials and other research results into potential new therapies. The material is divided into five main categories: Developmental biology and molecular neuro-oncology Pathological and clinical features of malignant brain tumors Models for the study of brain tumor invasion in vivo and in vitro Mechanisms of invasion New therapeutic strategies Brain Tumor Invasion offers dozens of maps and photographs that illustrate topics under discussion. This in-depth introduction to one of the most difficult problems in the management of brain tumors is indispensable to neuro-oncologists involved in brain tumor research and therapy. It is also useful to researchers in cancer biology, neuroscience, cell biology, and molecular genetics.

Resistance to Targeted Therapies Against Adult Brain Cancers

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Publisher : Springer
ISBN 13 : 3319465058
Total Pages : 267 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Resistance to Targeted Therapies Against Adult Brain Cancers by : Amanda Tivnan

Download or read book Resistance to Targeted Therapies Against Adult Brain Cancers written by Amanda Tivnan and published by Springer. This book was released on 2016-11-26 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume will bring together a review of research being carried out by international experts in this field, detailing treatment and research approaches in several forms of malignant brain tumors. These include glioblastoma (GBM), a highly aggressive and fatal form of astrocytoma which accounts for 80% of newly diagnosed brain tumor patients per year, and meningioma, of which 10% are malignant and extremely resistant to targeted therapies. The volume will also include a discussion of methods to overcome blood-brain barrier exclusion for more efficient targeted drug delivery in all forms of brain cancer treatment. The volume will include information on the repurposing of drugs in an attempt to circumvent drug resistance, use of small molecule inhibitors in GBM treatment, mechanisms of secondary brain metastasis, drug resistance, and state-of-the-art imaging of targeted therapies.

Cannabis

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Author :
Publisher : CRC Press
ISBN 13 : 1315350599
Total Pages : 543 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Cannabis by : Ernest Small

Download or read book Cannabis written by Ernest Small and published by CRC Press. This book was released on 2016-10-14 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cannabis sativa is best known as the source of marijuana, the world’s most widely consumed illicit recreational drug. However, the plant is also extremely useful as a source of stem fiber, edible seed oil, and medicinal compounds, all of which are undergoing extremely promising research, technological applications, and business investment. Indeed, despite its capacity for harm as a recreational drug, cannabis has phenomenal potential for providing new products to benefit society and for generating extensive employment and huge profits. Misguided policies, until recently, have prevented legitimate research on the beneficial properties of cannabis, but there is now an explosion of societal, scientific, and political support to reappraise and remove some of the barriers to usage. Unfortunately, there is also a corresponding dearth of objective analysis. Towards redressing the limitation of information, Cannabis: A Complete Guide is a comprehensive reference summarizing botanical, business, chemical, ecological, genetic, historical, horticultural, legal, and medical considerations that are critical for the wise advancement and management of cannabis in its various forms. This book documents both the risks and benefits of what is indisputably one of the world’s most important species. The conflicting claims for medicinal virtues and toxicological vices are examined, based mainly on the most recent authoritative scientific reviews. The attempt is made consistently to reflect majority scientific opinion, although many aspects of cannabis are controversial. Aside from the relevance to specialists, the general public should find the presentation attractive because of the huge interest today in marijuana. Unfortunately, society has become so specialized and compartmentalized that most people have limited appreciation of the importance of science to their lives, except when a topic like marijuana becomes sensationalized. This review of cannabis can serve as a vehicle for public education in the realm of science and technology. Indeed, towards the goal of disseminating the important information in this book to a wide audience, the presentation is user-friendly, concise, and well-illustrated in the hope that non-specialists will find the topics both informative and entertaining.

Computational Diffusion MRI

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Author :
Publisher : Springer Nature
ISBN 13 : 3030528936
Total Pages : 210 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Computational Diffusion MRI by : Elisenda Bonet-Carne

Download or read book Computational Diffusion MRI written by Elisenda Bonet-Carne and published by Springer Nature. This book was released on 2020-11-06 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume gathers papers presented at the Workshop on Computational Diffusion MRI (CDMRI 2019), held under the auspices of the International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI), which took place in Shenzhen, China on October 17, 2019. This book presents the latest advances in the rapidly expanding field of diffusion MRI. It shares new perspectives on the latest research challenges for those currently working in the field, but also offers a valuable starting point for anyone interested in learning about computational techniques in diffusion MRI. The book includes rigorous mathematical derivations, a wealth of rich, full-colour visualisations and extensive clinically relevant results. As such, it will be of interest to researchers and practitioners in the fields of computer science, MRI physics and applied mathematics. Readers will find contributions covering a broad range of topics, from the mathematical foundations of the diffusion process and signal generation, to new computational methods and estimation techniques for the in vivo recovery of microstructural and connectivity features, as well as diffusion-relaxometry and frontline applications in research and clinical practice. This edition includes invited works from high-profile researchers with a specific focus on three new and important topics that are gaining momentum within the diffusion MRI community, including diffusion MRI signal acquisition and processing strategies, machine learning for diffusion MRI, and diffusion MRI outside the brain and clinical applications.

Tumors of the Brain and Spine

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Publisher : Springer Science & Business Media
ISBN 13 : 0387292020
Total Pages : 368 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Tumors of the Brain and Spine by : Franco DeMonte

Download or read book Tumors of the Brain and Spine written by Franco DeMonte and published by Springer Science & Business Media. This book was released on 2007-05-10 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumors of the Brain and Spine focuses primarily on approaches to the treatment of benign, primary low-grade to high-grade, and metastatic tumors in the brain and spine, as practiced by surgeons and clinicians at the University of Texas M. D. Anderson Cancer Center. The book is written mainly for the primary care oncologist, general neurologist, and general neurosurgeon. Discussion of treatment coverage focuses on neurosurgery, chemotherapy, and radiation therapy, singly and in combination. Also included are chapters on symptom management, molecular genetics and neuropathology of intracranial tumors, leptomeningeal dissemination of systemic cancer, epidemiology of brain tumors, and innovative treatment strategies.

Glioblastoma: State of the Art and Future Perspectives

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Author :
Publisher : MDPI
ISBN 13 : 3039282603
Total Pages : 784 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Glioblastoma: State of the Art and Future Perspectives by : Ghazaleh Tabatabai

Download or read book Glioblastoma: State of the Art and Future Perspectives written by Ghazaleh Tabatabai and published by MDPI. This book was released on 2020-12-10 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glioblastoma is an aggressive incurable primary tumor of the central nervous system. Median overall survival is in the range of 1.5 years even in selected clinical trials populations. Many features contribute to this therapeutic challenge including high intratumoral and intertumoral heterogeneity, resistance to therapy, migration and invasion, immunosuppression. With the access of novel highthroughput technologies, significant progress has been made to understand molecular and immunological signatures underlying the pathology of glioblastoma. Clinical trial designs have shifted from investigating broad “one-for-all” treatment approaches to precision oncology designs. The collection of contributions in this book aim at providing researchers and clinicians an update on different aspects of glioblastoma, i.e. progress in basic, preclinical and clinical research.

Cause of Death: Ballistic Trauma

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Author :
Publisher : FriesenPress
ISBN 13 : 173900180X
Total Pages : 209 pages
Book Rating : 4.7/5 (39 download)

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Book Synopsis Cause of Death: Ballistic Trauma by : Scott D. Young

Download or read book Cause of Death: Ballistic Trauma written by Scott D. Young and published by FriesenPress. This book was released on 2024-06-04 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: On August 1, 1966, the United States and the rest of the world witnessed a mass shooting at the University of Texas at Austin that is still considered one of the most shocking and impactful mass murders in that country’s recent history. Charles Joseph Whitman was a twenty-five-year-old married student and ex-Marine who truly went “ballistic” on that day. Sniping from the domineering UT Tower he killed or wounded more than forty victims before being shot and killed by police. As a former Marine and excellent marksman, Whitman had extensive experience with firearms but had no history of criminal activity or mental illness. The shooting spree, therefore, left many scrambling for answers. A clue emerged from Whitman’s suicide note. In it, he said that he knew something was wrong with himself and requested that an autopsy be performed after his death. A malignant tumour was found deep in his brain, which ignited a fierce debate amongst medical experts about its role in Whitman’s final violent actions. Cause of Death: Ballistic Trauma seeks to settle this debate by explaining the mechanisms of how the tumour was instrumental in influencing Whitman’s behaviour. The book explores how obstructive hydrocephalus and temporal lobe seizures may have led to the destructive events on that fateful day. Written by retired medical oncologist, Dr. Scott Young, who spent more than twenty years caring for patients with brain tumours, this book explores the neuroscience behind this mass murder. Drawing upon problem-solving techniques used in forensics, and supported with extensive references and images, Young puts forth an argument that Charles Whitman was probably not legally responsible for his actions. This is his first book.

Molecular Markers of Brain Tumor Cells

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9781402027819
Total Pages : 396 pages
Book Rating : 4.0/5 (278 download)

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Book Synopsis Molecular Markers of Brain Tumor Cells by : Bela Bodey

Download or read book Molecular Markers of Brain Tumor Cells written by Bela Bodey and published by Springer Science & Business Media. This book was released on 2004-09-14 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Childhood brain tumors are a diverse group of diseases characterized by the abnormal growth of tissue contained within the skull. Other than leukemia and lymphoma, brain tumors are the most common type of neoplasms that occur in children. The leading cause of death from childhood neoplasms among persons up to 19 years is brain tumors. As such, this book is a review of the most recent molecular biological research concerning brain tumors with references and comparisons to a variety of neoplastic disorders. The book then uses this information to foreshadow the direction that future anti-neoplastic therapies will take. Because of the wide spectrum of the objectives of the book, any individual involved in cancer research will greatly benefit from the work. Histopathologists, neuropathologists, clinical and research oncologists, and medical students will find this book to be an invaluable resource as a reference guide. Patients and their families will also find the book useful as it offers a comprehensive update on new, non-classical therapeutic modality options and contains a detailed description and analysis of brain tumors. Such an endeavor has yet to be undertaken by any other book and may prove to be the most comprehensive book on brain tumors thus far.

Cardiorespiratory Fitness in Cardiometabolic Diseases

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Author :
Publisher : Springer
ISBN 13 : 3030048160
Total Pages : 443 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Cardiorespiratory Fitness in Cardiometabolic Diseases by : Peter Kokkinos

Download or read book Cardiorespiratory Fitness in Cardiometabolic Diseases written by Peter Kokkinos and published by Springer. This book was released on 2019-03-18 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the links between physical activity (PA), cardiorespiratory fitness (CRF), and cardiovascular and metabolic diseases. It presents an overview of the role of PA and CRF in the prevention and management of risk factors associated with cardiometabolic diseases such as hypertension, peripheral vascular disease, stroke, type 2 diabetes, metabolic syndrome, dyslipidemia, obesity, and atherosclerosis. In addition, it explores how these risks vary with different populations such as the elderly and people of various racial backgrounds. The book also highlights risks associated with exercise and presents a prescription for appropriate and efficacious exercise to minimize risk and maximize health benefits for the heart. Cardiorespiratory Fitness in Prevention and Management of Cardiometabolic Disease is an essential resource for physicians, exercise physiologists, medical students, residents, fellows, nurses, and researchers in cardiology, cardiorespiratory fitness, exercise science, health promotion and disease prevention, public health, and epidemiology.

Clinical Management and Evolving Novel Therapeutic Strategies for Patients with Brain Tumors

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Author :
Publisher : IntechOpen
ISBN 13 : 9789535110583
Total Pages : 654 pages
Book Rating : 4.1/5 (15 download)

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Book Synopsis Clinical Management and Evolving Novel Therapeutic Strategies for Patients with Brain Tumors by : Terry Lichtor

Download or read book Clinical Management and Evolving Novel Therapeutic Strategies for Patients with Brain Tumors written by Terry Lichtor and published by IntechOpen. This book was released on 2013-04-10 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: A dramatic increase in knowledge regarding the molecular biology of brain tumors has been established over the past few years, and this has lead to the development of novel therapeutic strategies for these patients. In this book a review of the options available for the clinical management of patients with these tumors are outlined. In addition advances in radiology both for pre-operative diagnostic purposes along with surgical planning are described. Furthermore a review of newer developments in chemotherapy along with the evolving field of photodynamic therapy both for intra-operative management and subsequent therapy is provided. A discussion of certain surgical management issues along with tumor induced epilepsy is included. Finally a discussion of the management of certain unique problems including brain metastases, brainstem glioma, central nervous system lymphoma along with issues involving patients with a brain tumor and pregnancy is provided.