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Molecular Cloning Of Hormone Genes
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Book Synopsis Molecular Cloning of Hormone Genes by : Joel F. Habener
Download or read book Molecular Cloning of Hormone Genes written by Joel F. Habener and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: The peptide hormones are small proteins that regulate cellular metabolism through their specific interactions with tissues of the endocrine, nervous, and immune systems, as well as in embry onic development. During the past ten years, refinements in the techniques of recombinant DNA technology have resulted in the cloning of genes encoding approximately 50 different hormonal and regulatory peptides, including those in which the peptides themselves and the mRNAs encoding the peptides are present in only trace amounts in the tissues of origin. In addition to provid ing the coding sequences of recognized hormonal and regulatory peptides, gene sequencing has uncovered new bioactive peptides encoded in the precursor pro hormones that are then liberated along with the hormonal peptides during cellular cleavages of the precursors. The encoding of multiple peptides in a single mono cistronic mRNA appears to be a genetic mechanism for the gener ation of biologic diversification without requiring amplification of gene sequences. Two of the objectives in the assembly of this book are to pre sent, in one volume, the known primary structures of the genes encoding several of the polypeptide hormones and related regulatory peptides, and to provide an account of the various ap proaches that have been used to identify and select the cloned genes encoding these polypeptides. The contents of the two in troductory chapters are intended to provide the reader with a brief background of the approaches to gene cloning and the struc ture and expression of hormone-encoding genes.
Book Synopsis Molecular Biology of The Cell by : Bruce Alberts
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis New Directions for Biosciences Research in Agriculture by : National Research Council
Download or read book New Directions for Biosciences Research in Agriculture written by National Research Council and published by National Academies Press. This book was released on 1985-01-01 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authored by an integrated committee of plant and animal scientists, this review of newer molecular genetic techniques and traditional research methods is presented as a compilation of high-reward opportunities for agricultural research. Directed to the Agricultural Research Service and the agricultural research community at large, the volume discusses biosciences research in genetic engineering, animal science, plant science, and plant diseases and insect pests. An optimal climate for productive research is discussed.
Book Synopsis Gene Regulation by Steroid Hormones III by : Arun K. Roy
Download or read book Gene Regulation by Steroid Hormones III written by Arun K. Roy and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of steroid hormone action has continued to expand into the realm of molecular biology at a pace even faster than most of us ever imagined. techniques of molecular biology have made it possible to clone The hormone-regulated genes and to examine steroid-receptor interactions with these genes. Nucleotide sequences of these genes, which show preferential binding of steroid receptors, have been identified. These results are complemented by the identification of chromatin acceptor proteins, which also show preferential binding for steroid-receptor complexes. Thus, one can envision the day when cloned genes, purified acceptor proteins, and receptor-steroid complexes will be recombined in vitro to form a functional unit. Cellular localization of steroid receptors has undergone recent revision, and it now appears that receptors are localized primarily in the nuclear compartment. These findings, although controversial, will lead to a reassessment of many of the previous concepts of steroid-receptor interactions and regulation. The way in which these observations at the of physiology, molecular and cellular levels fit into the overall scheme development, and evolution are continuing to progress, and the future promises some very exciting syntheses of understanding at all levels of biological organization. The third Meadow Brook Conference on hormones was held in order to bring together investigators who will undoubtedly contribute heavily to this future synthesis and to permit a free exchange of ideas and concepts as they relate to the current state-of-the-art in molecular endocrinology. Spring 1986 ARUN K. Roy JAMES H. CLARK Contents Preface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Download or read book Plant Hormones written by P.J. Davies and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 843 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant hormones play a crucial role in controlling the way in which plants growand develop. Whilemetabolism providesthepowerand buildingblocks for plant life, it is the hormones that regulate the speed of growth of the individual parts and integrate these parts to produce the form that we recognize as a plant. In addition, theyplayacontrolling role inthe processes of reproduction. This book is a description ofthese natural chemicals: how they are synthesizedand metabolized; howthey work; whatwe knowoftheir molecular biology; how we measure them; and a description ofsome ofthe roles they play in regulating plant growth and development. Emphasis has also been placed on the new findings on plant hormones deriving from the expanding use ofmolecular biology as a tool to understand these fascinating regulatory molecules. Even at the present time, when the role of genes in regulating all aspects of growth and development is considered of prime importance, it is still clear that the path of development is nonetheless very much under hormonal control, either via changes in hormone levels in response to changes in gene transcription, or with the hormones themselves as regulators ofgene transcription. This is not a conference proceedings, but a selected collection ofnewly written, integrated, illustrated reviews describing our knowledge of plant hormones, and the experimental work that is the foundation of this knowledge.
Book Synopsis Molecular Endocrinology by : Gill Rumsby
Download or read book Molecular Endocrinology written by Gill Rumsby and published by Garland Science. This book was released on 2020-07-26 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume in the Human Molecular Genetics series is an invaluable text for endocrinologists wishing to update their knowledge. It also provides an excellent grounding in the basic genetics of molecular endocrinology and relevant analytical techniques.
Book Synopsis Laboratory Methods in Enzymology: DNA by :
Download or read book Laboratory Methods in Enzymology: DNA written by and published by Elsevier. This book was released on 2013-09-02 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Enzymology volumes provide an indispensable tool for the researcher. Each volume is carefully written and edited by experts to contain state-of-the-art reviews and step-by-step protocols. In this volume, we have brought together a number of core protocols concentrating on DNA, complementing the traditional content that is found in past, present and future Methods in Enzymology volumes. Indispensable tool for the researcher Carefully written and edited by experts to contain step-by-step protocols In this volume we have brought together a number of core protocols concentrating on DNA
Author :National Institute of Arthritis, Metabolism, and Digestive Diseases (U.S.) Publisher : ISBN 13 : Total Pages :12 pages Book Rating :4.:/5 (319 download)
Book Synopsis Human Growth Hormone by : National Institute of Arthritis, Metabolism, and Digestive Diseases (U.S.)
Download or read book Human Growth Hormone written by National Institute of Arthritis, Metabolism, and Digestive Diseases (U.S.) and published by . This book was released on 1979 with total page 12 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Gene Cloning written by Julia Lodge and published by Garland Science. This book was released on 2007-01-24 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ability to successfully clone genes underlies the majority of our knowledge in molecular and cellular biology. Gene Cloning introduces the diverse array of techniques available to clone genes and how they can be used effectively both in the research laboratory, to gain knowledge about the gene, and for use in biotechnology, medicine, the pharmaceutical industry, and agriculture. It shows how cloning genes is an integral part of genomics and underlines its relevance in the post-genomic age, as a tool required to test predictions of gene regulation and function made through bioinformatics. Applications of gene cloning in medicine, both for diagnosis and treatment, and in the pharmaceutical industry and agriculture, are also covered in the book. Gene Cloning takes a fresh approach to teaching molecular and cellular biology and will be a valuable resource to both undergraduates and lecturers of biological and biomedical science courses.
Book Synopsis Safety of Genetically Engineered Foods by : National Research Council
Download or read book Safety of Genetically Engineered Foods written by National Research Council and published by National Academies Press. This book was released on 2004-07-08 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assists policymakers in evaluating the appropriate scientific methods for detecting unintended changes in food and assessing the potential for adverse health effects from genetically modified products. In this book, the committee recommended that greater scrutiny should be given to foods containing new compounds or unusual amounts of naturally occurring substances, regardless of the method used to create them. The book offers a framework to guide federal agencies in selecting the route of safety assessment. It identifies and recommends several pre- and post-market approaches to guide the assessment of unintended compositional changes that could result from genetically modified foods and research avenues to fill the knowledge gaps.
Download or read book Gene Cloning written by Lesley Tillman and published by Scientific e-Resources. This book was released on with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene cloning is the act of making copies, or clones, of a single gene. Once a gene is identified, clones can be used in many areas of biomedical and industrial research. Genetic engineering is the process of cloning genes into new organisms for altering the DNA sequence to change the protein product. Genetic engineering depends on our ability to perform the following essential procedures. Molecular cloning takes advantage of the fact that the chemical structure of DNA is fundamentally the same in all living organisms. The available information on gene cloning and transgenic development in horticulture crops has been compiled and it is hoped that this would be very useful to students and researchers in the field of biotechnology of horticulture crops. Therefore, if any segment of DNA from any organism is inserted into a DNA segment containing the molecular sequences required for DNA replication, and the resulting recombinant DNA is introduced into the organism from which the replication sequences were obtained, then the foreign DNA will be replicated along with the host cell's DNA in the transgenic organism. The book has been designed for students, research scholars and teachers involved in the field
Book Synopsis Gene Regulation by Steroid Hormones by : A.K. Roy
Download or read book Gene Regulation by Steroid Hormones written by A.K. Roy and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Within the last two decades endocrinological research has taken a definite tum toward biochemistry and molecular biology. This has resulted in a new discipline called' 'molecular endocrinology. " Studies on the mechanism of hormone action have continued to make headlines with fundamental discov eries in receptor action and gene regulation. Recently the insect endocrino logists have also begun to explore the molecular mechanism of steroid hor mone action taking advantage of the vast number of Drosophila mutants, the library of Drosophila gene, and several well-characterized cell-lines. The availability ofthe recombinant DNA technology has provided a truly revolu tionary tool in the hands of the molecular endocrinologists. "Gene Regula tion by Steroid Hormones" is compiled and presented in this frontier spirit, and we hope that this volume will serve not only the active investigators in the field but will also be very useful to students and researchers with a gen eral interest in regulatory biology. The book is an offshoot of the Conference on Molecular Mechanism of Steroid Hormone Action held at the Meadow Brook Mansion of Oakland University in the fall of 1978. We wish to acknowledge the financial assist ance from the National Science Foundation and Oakland University. The conferees will never forget the warmest hospitality of Dr. LOWELL EKLUND and his staff at the Meadow Brook center and we also wish to express per sonal gratitude to many of our students and colleagues for helping us to make the conference a great success.
Book Synopsis Genetic Engineering of Plants by : National Research Council
Download or read book Genetic Engineering of Plants written by National Research Council and published by National Academies Press. This book was released on 1984-02-01 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The book...is, in fact, a short text on the many practical problems...associated with translating the explosion in basic biotechnological research into the next Green Revolution," explains Economic Botany. The book is "a concise and accurate narrative, that also manages to be interesting and personal...a splendid little book." Biotechnology states, "Because of the clarity with which it is written, this thin volume makes a major contribution to improving public understanding of genetic engineering's potential for enlarging the world's food supply...and can be profitably read by practically anyone interested in application of molecular biology to improvement of productivity in agriculture."
Download or read book Gene Cloning written by David M. Glover and published by Springer. This book was released on 2013-12-19 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book was originallyconceived in the form ofa second edition ofa volume published in 1980 in Chapman and Hall's 'OutllneStudies in Biology' series and entitled Genetic Engineering - Cloning DNA. It very rapidly became apparent that with the impact ofrecombinant DNA techniques being feIt in so many areas ofblology, it was going to be difficultifnotimpossible to keepthe bookwithin the space confines of these little monographs. The stays were therefore loosened and the book expanded comfortably to its present size. I hope that this extra space has allowed me to clarify sections ofthe text that were 'heavy going' in the earlierversion. Theextraspace has certainlyallowed me to cover topics that were not mentioned at all in the earlier book. These are primarily to be found in Chapters 7 and 8, which cover the rapid advances that have been recently made in the use ofplantand animal cells as hosts for recombinant DNAmolecules. The develop ment ofother vectors has certainly not stood still over the past four years. This has necessitated a thorough revision ofChapters 3 and 4, which deal with bacteriophage and bacterial plasmid vectors. Numerous techniques for in vitromutagenesis have now been tried and tested allowing me to givecomprehensive coverage ofthisarea in Chapter 2 along with the biochemical techniques used to construct recombinant DNA molecules. Readers with some background knowledge of the approaches to gene cloning will be able to go straight toapart ofthe book in whichthey are specificallyinterested.
Book Synopsis Sources of Medical Technology by : Institute of Medicine
Download or read book Sources of Medical Technology written by Institute of Medicine and published by National Academies Press. This book was released on 1995-01-01 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evidence suggests that medical innovation is becoming increasingly dependent on interdisciplinary research and on the crossing of institutional boundaries. This volume focuses on the conditions governing the supply of new medical technologies and suggest that the boundaries between disciplines, institutions, and the private and public sectors have been redrawn and reshaped. Individual essays explore the nature, organization, and management of interdisciplinary R&D in medicine; the introduction into clinical practice of the laser, endoscopic innovations, cochlear implantation, cardiovascular imaging technologies, and synthetic insulin; the division of innovating labor in biotechnology; the government- industry-university interface; perspectives on industrial R&D management; and the growing intertwining of the public and proprietary in medical technology.
Book Synopsis Molecular Biology of Steroid and Nuclear Hormone Receptors by : Leonard Freedman
Download or read book Molecular Biology of Steroid and Nuclear Hormone Receptors written by Leonard Freedman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intracellular Receptors: New Instruments for a Symphony of Signals In the late eighteenth century, it was proposed on theoretical grounds that each of the body's organs, beginning with the brain, must be "a factory and laboratory of a specific humor which it returns to the blood", and that these circulating signals "are indispensable for the life of the whole" (Bordeu 1775). During the nineteenth cen tury, some remarkable physiological experiments revealed the actions of humoral factors that affected the for and function of multiple tissues, organs and organ sys tems within the body (Berthold 1849); much later, the chemical and molecular na ture of some of those factors was determined. Against this deep historical backdrop of the founding studies of intercellular signaling, molecular biology sprang into existence a mere forty years ago, rooted in the revelation of regulable gene expression in bacteria. But contemporaneous with those classical analyses of transcriptional regulation of the lactose operon, the mod em era of signal transduction was inaugurated by the identification of cAMP as a second messenger -- an intracellular mediator of hormonal activation of glycogen catabolism (Sutherland and RaIl 1960). Later in that same decade, it emerged that cAMP is a critical signal not only in metazoans, but even in bacteria, where it serves an analogous function as a critical switch that activates expression of genes re quired for catabolism of complex carbon sources, including those of the lactose operon.
Book Synopsis Guide to Biochemistry by : James C. Blackstock
Download or read book Guide to Biochemistry written by James C. Blackstock and published by Butterworth-Heinemann. This book was released on 2014-06-28 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Guide to Biochemistry provides a comprehensive account of the essential aspects of biochemistry. This book discusses a variety of topics, including biological molecules, enzymes, amino acids, nucleic acids, and eukaryotic cellular organizations. Organized into 19 chapters, this book begins with an overview of the construction of macromolecules from building-block molecules. This text then discusses the strengths of some weak acids and bases and explains the interaction of acids and bases involving the transfer of a proton from an acid to a base. Other chapters consider the effectiveness of enzymes, which can be appreciated through the comparison of spontaneous chemical reactions and enzyme-catalyzed reactions. This book discusses as well structure and function of lipids. The final chapter deals with the importance and applications of gene cloning in the fundamental biological research, which lies in the preparation of DNA fragments containing a specific gene. This book is a valuable resource for biochemists and students.
