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Molecular Chaperones And Folding Catalysts
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Book Synopsis Molecular Chaperones and Folding Catalysts by : Bernd Bakau
Download or read book Molecular Chaperones and Folding Catalysts written by Bernd Bakau and published by CRC Press. This book was released on 2003-09-02 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most intriguing discoveries in molecular biology in the last decade is the existence of an evolutionary conserved and essential system, consisting of molecular chaperones and folding catalysts, which promotes the folding of the proteins in the cell. This text summarizes our current knowledge of the cellular roles, the regulation and the mechanism of action of this system. It has a broad scope, covering cell biological, genetic and biochemical aspects of protein folding in cells from bacteria to man. Particularly appropriate to researchers working in basic and applied aspects of molecular medicine, this volume should also prove useful as an up-to-date reference book and as a textbook for specialized university courses.
Book Synopsis Guidebook to Molecular Chaperones and Protein-Folding Catalysts by : Mary-Jane Gething
Download or read book Guidebook to Molecular Chaperones and Protein-Folding Catalysts written by Mary-Jane Gething and published by OUP Oxford. This book was released on 1997-11-27 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: The precise shape of a protein is a crucial factor in its function. How do proteins become folded into the right conformation? Molecular chaperones and protein folding catalysts bind to developing polypeptides in the cytoplasm and ensure correct folding and transport. This Guidebook catalogues the latest information on nearly 200 of these molecules, including the important class of heat shock proteins; each entry is written by leading researchers in the field.
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book RNA Chaperones written by Tilman Heise and published by . This book was released on 2020 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a wide spectrum of methods to study RNA chaperones in vitro, at the single molecule level, and protocols useful for cell-based assays. Beginning with a section on a number of bacterial proteins for study, the volume also explores proteins from eukaryotic cells and how to delve into the complex interactions between RNA chaperones and the folding and unfolding of proteins. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, RNA Chaperones: Methods and Protocols serves as an ideal guide for scientists and students interested in RNA biology and RNA chaperones. Chapter 3 is available Open Access under a CC-BY 4.0 license via link.springer.com.
Download or read book Protein Folding in the Cell written by and published by Elsevier. This book was released on 2002-02-20 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Advances in Protein Chemistry provides a broad, yet deep look at the cellular components that assist protein folding in the cell. This area of research is relatively new--10 years ago these components were barely recognized, so this book is a particularly timely compilation of current information. Topics covered include a review of the structure and mechanism of the major chaperone components, prion formation in yeast, and the use of microarrays in studying stress response. Outlines preceding each chapter allow the reader to quickly access the subjects of greatest interest. The information presented in this book should appeal to biochemists, cell biologists, and structural biologists.
Book Synopsis Heat Shock Proteins in Cancer by : Stuart K. Calderwood
Download or read book Heat Shock Proteins in Cancer written by Stuart K. Calderwood and published by Springer Science & Business Media. This book was released on 2007-09-09 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heat shock proteins are emerging as important molecules in the development of cancer and as key targets in cancer therapy. These proteins enhance the growth of cancer cells and protect tumors from treatments such as drugs or surgery. However, new drugs have recently been developed particularly those targeting heat shock protein 90. As heat shock protein 90 functions to stabilize many of the oncogenes and growth promoting proteins in cancer cells, such drugs have broad specificity in many types of cancer cell and offer the possibility of evading the development of resistance through point mutation or use of compensatory pathways. Heat shock proteins have a further property that makes them tempting targets in cancer immunotherapy. These proteins have the ability to induce an inflammatory response when released in tumors and to carry tumor antigens to antigen presenting cells. They have thus become important components of anticancer vaccines. Overall, heat shock proteins are important new targets in molecular cancer therapy and can be approached in a number of contrasting approaches to therapy.
Book Synopsis Oxidative Folding of Peptides and Proteins by : Luis Moroder
Download or read book Oxidative Folding of Peptides and Proteins written by Luis Moroder and published by Royal Society of Chemistry. This book was released on 2009 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions from experts in the field, this book provides a comprehensive overview of the oxidative folding of cysteine-rich peptides.
Book Synopsis Post-Transcriptional Control of Gene Expression in Plants by : Witold Filipowicz
Download or read book Post-Transcriptional Control of Gene Expression in Plants written by Witold Filipowicz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: A recent volume of this series (Signals and Signal Transduction Pathways in Plants (K. Palme, ed.) Plant Molecular Biology 26, 1237-1679) described the relay races by which signals are transported in plants from the sites of stimuli to the gene expression machinery of the cell. Part of this machinery, the transcription apparatus, has been well studied in the last two decades, and many important mechanisms controlling gene expression at the transcriptional level have been elucidated. However, control of gene expression is by no means complete once the RNA has been produced. Important regulatory devices determine the maturation and usage of mRNA and the fate of its translation product. Post-transcriptional regulation is especially important for generating a fast response to environmental and intracellular signals. This book summarizes recent progress in the area of post-transcriptional regulation of gene expression in plants. 18 chapters of the book address problems of RNA processing and stability, regulation of translation, protein folding and degradation, as well as intracellular and cell-to-cell transport of proteins and nucleic acids. Several chapters are devoted to the processes taking place in plant organelles.
Book Synopsis Encyclopedia of Signaling Molecules by : Sangdun Choi
Download or read book Encyclopedia of Signaling Molecules written by Sangdun Choi and published by Springer. This book was released on 2012-07-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological processes are driven by complex systems of functionally interacting signaling molecules. Thus, understanding signaling molecules is essential to explain normal or pathological biological phenomena. A large body of clinical and experimental data has been accumulated over these years, albeit in fragmented state. Hence, systems biological approaches concomitant with the understanding of each molecule are ideal to delineate signaling networks/pathways involved in the biologically important processes. The control of these signaling pathways will enrich our healthier life. Currently, there are more than 30,000 genes in human genome. However, not all the proteins encoded by these genes work equally in order to maintain homeostasis. Understanding the important signaling molecules as completely as possible will significantly improve our research-based teaching and scientific capabilities. This encyclopedia presents 350 biologically important signaling molecules and the content is built on the core concepts of their functions along with early findings written by some of the world’s foremost experts. The molecules are described by recognized leaders in each molecule. The interactions of these single molecules in signal transduction networks will also be explored. This encyclopedia marks a new era in overview of current cellular signaling molecules for the specialist and the interested non-specialist alike During past years, there were multiple databases to gather this information briefly and very partially. Amidst the excitement of these findings, one of the great scientific tasks of the coming century is to bring all the useful information into a place. Such an approach is arduous but at the end will infuse the lacunas and considerably be a streamline in the understanding of vibrant signaling networks. Based on this easy-approach, we can build up more complicated biological systems.
Book Synopsis Macromolecular Protein Complexes II: Structure and Function by : J. Robin Harris
Download or read book Macromolecular Protein Complexes II: Structure and Function written by J. Robin Harris and published by Springer Nature. This book was released on 2020-01-14 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book follows on from Volume 83 in the SCBI series (“Macromolecular Protein Complexes”), and addresses several important topics (such as the Proteasome, Anaphase Promoting Complex, Ribosome and Apoptosome) that were not previously included, together with a number of additional exciting topics in this rapidly expanding field of study. Although the first SCBI Protein Complex book focused on soluble protein complexes, the second (Vol. 87)addressed Membrane Complexes, and the third (Vol. 88) put the spotlight on Viral Protein and Nucleoprotein Complexes, a number of membrane, virus and even fibrillar protein complexes have been be considered for inclusion in the present book. A further book is also under preparation that follows the same pattern, in an attempt to provide a thorough coverage of the subject. Chapter 9 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Book Synopsis The Chaperonins by : Robert L. Ellis
Download or read book The Chaperonins written by Robert L. Ellis and published by Elsevier. This book was released on 1996-04-01 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first of its kind, this volume presents the latest research findings on the chaperonins, the best studied family of a class of proteins known as molecular chaperones. These findings are changing our view of some fundamental cellular processes involving proteins, especially how proteins fold into their functional conformations. - Origins of the new view of protein folding - Prokaryotic chaperonins - Eukaryotic chaperonins - Evolution of the chaperonins - Refolding of denatured proteins - Organelle biosynthesis - Biomedical aspects
Book Synopsis Protein Folding by : Cláudio M. Gomes
Download or read book Protein Folding written by Cláudio M. Gomes and published by Springer. This book was released on 2019-02-25 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: This snapshot volume is designed to provide a smooth entry into the field of protein folding. Presented in a concise manner, each section introduces key concepts while providing a brief overview of the relevant literature. Outlook subsections will pinpoint specific aspects related to emerging methodologies, concepts and trends.
Book Synopsis Genetic Enhancement of Crops for Tolerance to Abiotic Stress: Mechanisms and Approaches, Vol. I by : Vijay Rani Rajpal
Download or read book Genetic Enhancement of Crops for Tolerance to Abiotic Stress: Mechanisms and Approaches, Vol. I written by Vijay Rani Rajpal and published by Springer. This book was released on 2019-04-24 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abiotic stresses such as drought (water deficit), extreme temperatures (cold, frost and heat), salinity (sodicity) and mineral (metal and metalloid) toxicity limit productivity of crop plants worldwide and are big threats to global food security. With worsening climate change scenarios, these stresses will further increase in intensity and frequency. Improving tolerance to abiotic stresses, therefore, has become a major objective in crop breeding programs. A lot of research has been conducted on the regulatory mechanisms, signaling pathways governing these abiotic stresses, and cross talk among them in various model and non-model species. Also, various ‘omics’ platforms have been utilized to unravel the candidate genes underpinning various abiotic stresses, which have increased our understanding of the tolerance mechanisms at structural, physiological, transcriptional and molecular level. Further, a wealth of information has been generated on the role of chromatin assembly and its remodeling under stress and on the epigenetic dynamics via histones modifications. The book consolidates outlooks, perspectives and updates on the research conducted by scientists in the abovementioned areas. The information covered in this book will therefore interest workers in all areas of plant sciences. The results presented on multiple crops will be useful to scientists in building strategies to counter these stresses in plants. In addition, students who are beginners in the areas of abiotic stress tolerance will find this book handy to clear their concepts and to get an update on the research conducted in various crops at one place
Book Synopsis Protein Refolding by : George Georgiou
Download or read book Protein Refolding written by George Georgiou and published by . This book was released on 1991 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: the refolding process is often the critical bottleneck in the production of high-value proteins, and recently acquired insights have yet to be translated into technological advantages. These proceedings bridge the gap between fundamental and applied studies, addressing such issues as in vivo protein folding, protein aggregation and inclusion body formation, elucidation of the folding pathway, characterization of folding intermediates, and practical considerations in protein renaturation. The symposium was part of the 199th ACS National Meeting, Boston, April 1990. Annotation copyrighted by Book News, Inc., Portland, OR
Book Synopsis Biology for AP ® Courses by : Julianne Zedalis
Download or read book Biology for AP ® Courses written by Julianne Zedalis and published by . This book was released on 2017-10-16 with total page 1923 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.
Book Synopsis The Exocrine Pancreas by : Stephen Pandol
Download or read book The Exocrine Pancreas written by Stephen Pandol and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 66 pages. Available in PDF, EPUB and Kindle. Book excerpt: The secretions of the exocrine pancreas provide for digestion of a meal into components that are then available for processing and absorption by the intestinal epithelium. Without the exocrine pancreas, malabsorption and malnutrition result. This chapter describes the cellular participants responsible for the secretion of digestive enzymes and fluid that in combination provide a pancreatic secretion that accomplishes the digestive functions of the gland. Key cellular participants, the acinar cell and the duct cell, are responsible for digestive enzyme and fluid secretion, respectively, of the exocrine pancreas. This chapter describes the neurohumoral pathways that mediate the pancreatic response to a meal as well as details of the cellular mechanisms that are necessary for the organ responses, including protein synthesis and transport and ion transports, and the regulation of these responses by intracellular signaling systems. Examples of pancreatic diseases resulting from dysfunction in cellular mechanisms provide emphasis of the importance of the normal physiologic mechanisms.
Book Synopsis Abiotic Stress Response in Plants by : Narendra Tuteja
Download or read book Abiotic Stress Response in Plants written by Narendra Tuteja and published by John Wiley & Sons. This book was released on 2016-01-08 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding abiotic stress responses in plants is critical for the development of new varieties of crops, which are better adapted to harsh climate conditions. The new book by the well-known editor team Narendra Tuteja and Sarvajeet Gill provides a comprehensive overview on the molecular basis of plant responses to external stress like drought or heavy metals, to aid in the engineering of stress resistant crops. After a general introduction into the topic, the following sections deal with specific signaling pathways mediating plant stress response. The last part covers translational plant physiology, describing several examples of the development of more stress-resistant crop varieties.
