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Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Derek J. Sullivan
Publisher : Caister Academic Press Limited
ISBN 13 : 9781908230447
Total Pages : 0 pages
Book Rating : 4.2/5 (34 download)
Download or read book Human Pathogenic Fungi written by Derek J. Sullivan and published by Caister Academic Press Limited. This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungi cause a spectrum of diseases in humans, ranging from comparatively innocuous superficial skin diseases caused by dermatophytes to invasive life-threatening infections caused by species such as Candida albicans, or Cryptococcus neoformans. Due to the opportunistic nature of most invasive mycoses, fungal pathogenicity has proven difficult to define. However, the application of new genomic and other molecular techniques in recent years has revolutionized the field, revealing fascinating new insights into the mechanisms of fungal pathogenesis. In this book, a panel of high profile contributors critically review the most important research to provide a timely overview. The book is divided into two sections. The first six chapters review the transformative effect of applying state-of-the-art tools and innovative approaches to research, particularly in the area of comparative biology. The second section consists of eight chapters, each dedicated to the molecular and cellular biology of a major fungal pathogen of humans: Candida, Aspergillus, Cryptococcus, Dermatophytes, Histoplasma, Blastomyces, Pneumocystis, and Paracoccidoides. These chapters provide a timely snapshot of the current state of research. The book will be an essential reference for students, researchers, and clinicians with an interest in fungal pathogenesis. [Subject: Molecular Biology, Epidemiology, Life Science
Author : Gioconda San-Blas
Publisher : Caister Academic Press Limited
ISBN 13 :
Total Pages : 392 pages
Book Rating : 4.3/5 (91 download)
Download or read book Pathogenic Fungi written by Gioconda San-Blas and published by Caister Academic Press Limited. This book was released on 2004 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past decade has witnessed a mushrooming of research in the area of medical mycology. San-Blas (Venezuela Institute of Scientific Investigation) and Calderone (Georgetown University) present recent work in the field. Papers on fungal dimorphism and pathogenicity focus on morphogenesis, the cell cycle, and the cell wall of human pathogens, while.
Author : Gioconda San-Blas
Publisher : Caister Academic Press Limited
ISBN 13 : 9781904455325
Total Pages : 0 pages
Book Rating : 4.4/5 (553 download)
Download or read book Pathogenic Fungi written by Gioconda San-Blas and published by Caister Academic Press Limited. This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the development of new molecular biology tools and the elucidation of whole genome sequences have revolutionized research on pathogenic fungi. Such advances have led to the development of faster, more reliable, diagnostic techniques for medically important pathogens such as Candida albicans, Aspergillus fumigatus, and Cryptococcus neoformans. In addition, they have led to a major breakthrough in the approach for the generation of novel anti-fungal agents. Now it is possible to search for agents that target essential genes. Research in this area has never been more exciting. In this book, a panel of expert international mycologists critically review the most important cutting-edge topics. Chapters are written from a molecular and genomic perspective, and through the provision of extensive reference sections positively encourage readers to pursue the subject in greater detail. Topics include: gene expression and regulation, heterozygosity in Candida, molecular diagnosis, regulation of the host-fungal interaction, the development of anti-fungals, signal transduction, and mechanisms of multi-drug resistance. The book will be essential reading for everyone with an interest in pathogenic fungi including mycologists, biotechnologists, molecular biologists, and pharmaceutical and biotechnology companies.
Author : Bruno Maresca
Publisher : Telos Press, Limited
ISBN 13 :
Total Pages : 612 pages
Book Rating : 4.F/5 ( download)
Download or read book Molecular Biology of Pathogenic Fungi written by Bruno Maresca and published by Telos Press, Limited. This book was released on 1994 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Heinz D. Osiewacz
Publisher : CRC Press
ISBN 13 : 9780203910719
Total Pages : 632 pages
Book Rating : 4.9/5 (17 download)
Download or read book Molecular Biology of Fungal Development written by Heinz D. Osiewacz and published by CRC Press. This book was released on 2002-05-07 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing an overview of the fundamental aspects of molecular fungal development, this book covers different elements in the maturational and reproductive cycles of selected fungal taxa. Illustrating various molecular pathways in parasites and hosts, the book explores the development of interventional strategies for combating disease. Highlights in
Author : José Pérez Martín
Publisher : Springer Science & Business Media
ISBN 13 : 3642229158
Total Pages : 294 pages
Book Rating : 4.6/5 (422 download)
Download or read book Morphogenesis and Pathogenicity in Fungi written by José Pérez Martín and published by Springer Science & Business Media. This book was released on 2012-01-07 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious fungal diseases continue to take their toll in terms of human suffering and enormous economic losses. Invasive infections by opportunistic fungal pathogens are a major cause of morbidity and mortality in immuno-compromised individuals. At the same time, plant pathogenic fungi have devastating effects on crop production and human health. New strategies for antifungal control are required to meet the challenges posed by these agents, and such approaches can only be developed through the identification of novel biochemical and molecular targets. However, in contrast to bacterial pathogens, fungi display a wealth of “lifestyles” and modes of infection. This diversity makes it extremely difficult to identify individual, evolutionarily conserved virulence determinants and represents a major stumbling block in the search for common antifungal targets. In order to activate the infection programme, all fungal pathogens must undergo appropriate developmental transitions that involve cellular differentiation and the introduction of a new morphogenetic programme. How growth, cell cycle progression and morphogenesis are co-ordinately regulated during development has been an active area of research in fungal model systems such as budding and fission yeast. By contrast, we have only limited knowledge of how these developmental processes shape fungal pathogenicity, or of the role of the cell cycle and morphogenesis regulators as true virulence factors. This book combines state-of-the-art expertise from diverse pathogen model systems to update our current understanding of the regulation of fungal morphogenesis as a key determinant of pathogenicity in fungi.
Author : John A. Bailey
Publisher : Springer Science & Business Media
ISBN 13 : 3642828493
Total Pages : 404 pages
Book Rating : 4.6/5 (428 download)
Download or read book Biology and Molecular Biology of Plant-Pathogen Interactions written by John A. Bailey and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collection of papers presented at a NATO Advanced Research Workshop on "Biology and Molecular Biology of Plant-Pathogen Interactions" which was held at Dillington College, Ilminster, UK, 1-6 September 1985. It had been preceded by Advanced Study Institutes at Porte Conte, Sardinia in 1975 and at Cape Sounion, Greece in 1981. In recent years, methods for the manipulation and transfer of genes have revolutionized our understanding of gene structure and function. It was thus opportune to bring together scientists from distinct disciplines, e. g. plant pathology, cytology, biochemistry and molecular biology to discuss our present understanding of cellular interactions between plants. We also explored how the potential offered by the newer molecular technologies could best be realized. It soon became evident at the Workshop, and is a repeated theme of this publication, that future research will need concentrated multi disciplinary programmes. Many of the new approaches will be valuable. For example, immunocytochemistry does, for the first time, allow molecules to be located precisely within infected tissues. Equally, the methods of DNA isolation and gene transformation will facilitate the isolation and characterization of genes associated with pathogenesis and specificity. The description at the Workshop of immunocytochemical protocols and of transformation systems for pathogenic fungi have already stimulated an upsurge in research on plant-pathogen relationships. The papers discuss many interactions between plants and fungal and bacterial pathogens, but also provide a comparison with mycorrhizal and symbiotic relationships, and those involving mycoparasites.
Author : D. Kerridge
Publisher : Springer Science & Business Media
ISBN 13 : 1461528348
Total Pages : 414 pages
Book Rating : 4.4/5 (615 download)
Download or read book Dimorphic Fungi in Biology and Medicine written by D. Kerridge and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungal dimorphism is a topic that sounds inherently too rarified to attract more than a specialist audience. Yet some 230 individuals representing an eclectic mixture of interests, from basic science to medical practice, gathered in Churchill College, Cambridge in Semptember 1992 for a meeting devoted only to this subject. The symposium was the fourth in a series "Topics in Mycology" to be jointly organized by the Janssen Research Foundation and the International Society for Human and Animal Mycology. The participants enjoyed a rich and varied diet of oral presentations and poster displays in the field of fungal morphogenesis. This book sets down in print the material presented at the dimorphism symposium. We think that the high quality of these papers conveys very well the flavor of what was an excellent meeting. The selection of contributions in this volume covers very wide ground indeed. Chapters devoted to some non-pathogenic fungi are included, because the scientific basis of morphological development belongs to the fields of cellular and molecular biology: it does not recognize the boundary imposed by considerations of virulence of a fungus for a human host. Yet morphogenetic change in those fungi that do cause human disease frequently appears to be a component of the pathological process: many important pathogens change from a hyphal form in the external environment to a round form in infected tissues. This relationship between dimorphism and pathogenicity is the point of contact between pure biology and medicine.
Author : Alexandra C. Brand
Publisher : Humana Press
ISBN 13 : 9781617795381
Total Pages : 597 pages
Book Rating : 4.7/5 (953 download)
Download or read book Host-Fungus Interactions written by Alexandra C. Brand and published by Humana Press. This book was released on 2012-02-09 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbiologists, medical mycologists, immunologists, and biochemists are increasingly working together to focus on the processes involved in the progression and treatment of fungal disease. Host-Fungus Interactions: Methods and Protocols is designed for research scientists who are involved in this work and interested in undertaking new or comparative studies of interactions between the mammalian host and clinically important fungal pathogens. Aiming to combine approaches for reverse genetics in pathogenic fungi with methods for their application in in vitro and in vivo models of disease, the book includes methods for the culture and genetic manipulation of the primary fungal pathogens and the opportunistic pathogens, as well as methods for investigating host-fungus interactions in model systems. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, Host-Fungus Interactions: Methods and Protocols describes available molecular methods and fungal infection models in great detail in order to encourage researchers to try new approaches to investigating host-fungus interactions with added levels of confidence.
Author : Rajendra Prasad
Publisher : Springer Science & Business Media
ISBN 13 : 3642752535
Total Pages : 273 pages
Book Rating : 4.6/5 (427 download)
Download or read book Candida Albicans written by Rajendra Prasad and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Candida, which was discovered more than a century ago as a causative organism of oral thrush, is now thought to potentially infect almost every tissue of the human body. Although we still do not have a safe anti-candida drug, the growing pace of progess of research on Candida albicans holds promise that a breakthrough is imminent. Though many monographs and articles on candida and candidoses have appeared in recent years, they mostly cover the clinical aspects. This particular text, however, explains the more basic features of candida including the molecular genetics, molecular biology and immunology of the cell wall, the molecular basis of morphogenesis and the structure and function of the plasma membrane. The role of anti-candida drugs and their mechanism of action are also discussed.
Author : WA Shipton
Publisher : PartridgeIndia
ISBN 13 : 1482894769
Total Pages : 311 pages
Book Rating : 4.4/5 (828 download)
Download or read book The Biology of Fungi Impacting Human Health written by WA Shipton and published by PartridgeIndia. This book was released on 2014 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungi have become increasingly significant determinants of human health and may cause as heavy a burden to health as viruses, bacteria and parasites. This outcome has occurred on account of the rise in diseases affecting the immune system and in the risk factors associated with advances in technologies used to treat various diseases and human conditions. These trends are no more evident than in tropical locations. This text emphasizes the biology of fungi impacting human health, with an emphasis on the Asia-Pacific region. The author draws on his own experience working in tropical Australia, Papua New Guinea and Thailand. A range of information is presented on the natural relationships of fungi, which helps the reader to understand the interactions these microbes engage in with other living organisms including plants and microfauna. Highlighted are the abilities of fungi to survive in soil, on plants and animals and their capacity to adapt to changing conditions and evade attempts to control them. The successes and problems encountered in controlling fungi biologically are outlined, including the development of vaccines. Practical methods to limit the impact of mycotoxins produced by fungi are suggested, including moderating plant growth conditions and being aware of human nutritional status.
Author : Joseph Heitman
Publisher : John Wiley & Sons
ISBN 13 : 1555819583
Total Pages : 1136 pages
Book Rating : 4.5/5 (558 download)
Download or read book The Fungal Kingdom written by Joseph Heitman and published by John Wiley & Sons. This book was released on 2020-07-10 with total page 1136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungi research and knowledge grew rapidly following recent advances in genetics and genomics. This book synthesizes new knowledge with existing information to stimulate new scientific questions and propel fungal scientists on to the next stages of research. This book is a comprehensive guide on fungi, environmental sensing, genetics, genomics, interactions with microbes, plants, insects, and humans, technological applications, and natural product development.
Author : Rajendra Prasad
Publisher : CRC Press
ISBN 13 : 9780849347948
Total Pages : 306 pages
Book Rating : 4.3/5 (479 download)
Download or read book Lipids of Pathogenic Fungi written by Rajendra Prasad and published by CRC Press. This book was released on 1996-08-06 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increases in various fungal infections due to Candida, Aspergillus, Blastomyces, Histoplasma spp., and Dermatophytes have attracted interest in the biochemistry of the fungal pathogens responsible. This book discusses the importance of lipids in pathogenic fungi and how they are involved in infections that pose serious health problems. The role of lipids in dimorphism, adherence, and virulence of fungi is investigated as is their composition and metabolism. Several chapters are devoted to examinations of specific pathogenic fungi, which will be particularly useful to researchers studying the clinical manifestations of infections caused by these factors. Later chapters present possible antifungal agents and nonconventional agents that target the organisms discussed earlier. Collectively, the contributions to this volume provide an excellent overview of this field. This text is essential for practicing clinicians and for everyone involved in the important task of resolving the problems associated with fungal pathogenicity.
Author : Ulf Stahl
Publisher : Wiley-VCH
ISBN 13 :
Total Pages : 296 pages
Book Rating : 4.3/5 (91 download)
Download or read book Molecular Biology of Filamentous Fungi written by Ulf Stahl and published by Wiley-VCH. This book was released on 1992 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: From an August 1991 workshop in Berlin under the auspices of the European Molecular Biology Organization, 19 papers focus on two major topics: the molecular biology of pathogenic fungi, including a session on new molecular tools available for studying fungal systems; and gene expression in fungal systems, including the complex regulation of metabolic pathways, applied aspects of expression signals, and the regulation of development, mating, and reproduction. Reproduced typescripts. Annotation copyright by Book News, Inc., Portland, OR
Author : Oliver Kurzai
Publisher : Springer Science & Business Media
ISBN 13 : 3642394329
Total Pages : 312 pages
Book Rating : 4.6/5 (423 download)
Download or read book Human Fungal Pathogens written by Oliver Kurzai and published by Springer Science & Business Media. This book was released on 2013-11-29 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Whereas plant and insect infections are commonly caused by fungi, only a small minority of the vast diversity of fungal species is pathogenic to humans. Despite this, fungal infections cause considerable morbidity and mortality worldwide. This volume is dedicated to the biology, clinical presentation and management of invasive fungal infections. Major pathogenic fungi are introduced by world-leading experts and the basic principles of fungal virulence are reviewed in the light of new results and experimental technologies that offer unprecedented insights into invasive infections caused by Aspergillus, Candida, Cryptococcus, Pneumocystis and Mucorales. In parallel, the clinical presentation of invasive fungal infections and current approaches to their diagnosis and treatment are summarized to provide an overview of human pathogenic fungi, linking pathogen biology to the clinical presentation of disease.
Author : Thomas Lion
Publisher : Humana
ISBN 13 : 9781493965137
Total Pages : 0 pages
Book Rating : 4.9/5 (651 download)
Download or read book Human Fungal Pathogen Identification written by Thomas Lion and published by Humana. This book was released on 2016-11-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume presents timely and authoritative content offering a comprehensive overview of the current state of the art in fungal diagnostics. Moreover, it addresses on-going developments expected to provide a basis for targeted treatment strategies resulting in improved outcome of invasive mycoses. The knowledge of host-related predisposing factors and stratified treatment options facilitating timely onset of adequate antifungal therapy are critical for successful clinical management and outcome of invasive fungal disease (IFD), requiring not only rapid diagnosis of a fungal infection and identification of the causative species, but also assessment of pathogen/host factors related to pathogenicity, susceptibility, and response to treatment. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Human Fungal Pathogen Identification: Methods and Protocols serves as an ideal reference for researchers investigating the ever-growing worldwide healthcare problems involving fungal infections.
