Molecular Biology Of Drug Addiction

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Molecular Biology of Drug Addiction

Author : Rafael Maldonado
Publisher : Springer Science & Business Media
ISBN 13 : 1592593437
Total Pages : 344 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Molecular Biology of Drug Addiction by : Rafael Maldonado

Download or read book Molecular Biology of Drug Addiction written by Rafael Maldonado and published by Springer Science & Business Media. This book was released on 2002-09-12 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive multidisciplinary review of the most relevant molecular, genetic, and behavioral approaches used to investigate the neurobiological basis of drug addiction. The authors explore the latest findings on opioid, psychostimulant, cannabinoid, alcohol, and nicotine addiction, provide fresh insights into the genetic basis of drug addiction and the new therapeutic perspectives these have opened. They describe the technology available to generate conditional knockout mice and show how these mice can reveal the molecular basis of opioid, psychostimulant, and cannabinoid addiction. They also review the different behavioral models available to evaluate the rewarding effects of drugs and analyze the genes involved in alcohol dependence.

Drugs, Brains, and Behavior

Author :
Publisher :
ISBN 13 :
Total Pages : 76 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Drugs, Brains, and Behavior by :

Download or read book Drugs, Brains, and Behavior written by and published by . This book was released on 2007 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cell Biology of Addiction

Author : Bertha Madras
Publisher : CSHL Press
ISBN 13 : 0879697539
Total Pages : 478 pages
Book Rating : 4.8/5 (796 download)

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Book Synopsis Cell Biology of Addiction by : Bertha Madras

Download or read book Cell Biology of Addiction written by Bertha Madras and published by CSHL Press. This book was released on 2006 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph, written by experts in the field, is devoted to the molecular analysis of addiction pathways in the brain. It provides an intensive overview of the fundamentals, stateDSofDStheDSart advances, and major gaps in the cell and molecular biology of drug addiction within the broader context of neuroscience. Addiction research is a branch of neuroscience and psychology. The emphasis in this book is on hard science and the market for it will be found among research investigators and grad students within the field of neuroscience. The research presented is not only applicable to the study of drug abuse and addiction, but has clear implications for clarifying mechanisms of learning and memory, neuroadaptation, perception, volitional behavior, motivation, reward, and other disciplines of neuroscience.

Biological Research on Addiction

Author :
Publisher : Academic Press
ISBN 13 : 0123983606
Total Pages : 759 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Biological Research on Addiction by :

Download or read book Biological Research on Addiction written by and published by Academic Press. This book was released on 2013-05-17 with total page 759 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological Research on Addiction examines the neurobiological mechanisms of drug use and drug addiction, describing how the brain responds to addictive substances as well as how it is affected by drugs of abuse. The book's four main sections examine behavioral and molecular biology; neuroscience; genetics; and neuroimaging and neuropharmacology as they relate to the addictive process. This volume is especially effective in presenting current knowledge on the key neurobiological and genetic elements in an individual’s susceptibility to drug dependence, as well as the processes by which some individuals proceed from casual drug use to drug dependence. Biological Research on Addiction is one of three volumes comprising the 2,500-page series, Comprehensive Addictive Behaviors and Disorders. This series provides the most complete collection of current knowledge on addictive behaviors and disorders to date. In short, it is the definitive reference work on addictions. Each article provides glossary, full references, suggested readings, and a list of web resources Edited and authored by the leaders in the field around the globe – the broadest, most expert coverage available Discusses the genetic basis of addiction Covers basic science research from a variety of animal studies

The Biology of Desire

Author : Marc Lewis
Publisher : PublicAffairs
ISBN 13 : 1610394380
Total Pages : 256 pages
Book Rating : 4.6/5 (13 download)

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Book Synopsis The Biology of Desire by : Marc Lewis

Download or read book The Biology of Desire written by Marc Lewis and published by PublicAffairs. This book was released on 2015-07-14 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Through the vivid, true stories of five people who journeyed into and out of addiction, a renowned neuroscientist explains why the "disease model" of addiction is wrong and illuminates the path to recovery. The psychiatric establishment and rehab industry in the Western world have branded addiction a brain disease. But in The Biology of Desire, cognitive neuroscientist and former addict Marc Lewis makes a convincing case that addiction is not a disease, and shows why the disease model has become an obstacle to healing. Lewis reveals addiction as an unintended consequence of the brain doing what it's supposed to do-seek pleasure and relief-in a world that's not cooperating. As a result, most treatment based on the disease model fails. Lewis shows how treatment can be retooled to achieve lasting recovery. This is enlightening and optimistic reading for anyone who has wrestled with addiction either personally or professionally.

Addiction

Author : Avram Goldstein
Publisher : Oxford University Press
ISBN 13 : 0195146646
Total Pages : 368 pages
Book Rating : 4.1/5 (951 download)

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Book Synopsis Addiction by : Avram Goldstein

Download or read book Addiction written by Avram Goldstein and published by Oxford University Press. This book was released on 2001 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug addiction as a brain disease is this book's theme. In clear scientific terms it describes the nature of chemical addiction and addictive behaviour and the muddied effort to develop effective drug control policies and laws.

Never Enough

Author : Judith Grisel
Publisher : Anchor
ISBN 13 : 0525434909
Total Pages : 258 pages
Book Rating : 4.5/5 (254 download)

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Book Synopsis Never Enough by : Judith Grisel

Download or read book Never Enough written by Judith Grisel and published by Anchor. This book was released on 2020-01-14 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: A NEW YORK TIMES BESTSELLER From a renowned behavioral neuroscientist and recovering addict, a rare page-turning work of science that draws on personal insights to reveal how drugs work, the dangerous hold they can take on the brain, and the surprising way to combat today's epidemic of addiction. Judith Grisel was a daily drug user and college dropout when she began to consider that her addiction might have a cure, one that she herself could perhaps discover by studying the brain. Now, after twenty-five years as a neuroscientist, she shares what she and other scientists have learned about addiction, enriched by captivating glimpses of her personal journey. In Never Enough, Grisel reveals the unfortunate bottom line of all regular drug use: there is no such thing as a free lunch. All drugs act on the brain in a way that diminishes their enjoyable effects and creates unpleasant ones with repeated use. Yet they have their appeal, and Grisel draws on anecdotes both comic and tragic from her own days of using as she limns the science behind the love of various drugs, from marijuana to alcohol, opiates to psychedelics, speed to spice. With more than one in five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide, and Grisel delves with compassion into the science of this scourge. She points to what is different about the brains of addicts even before they first pick up a drink or drug, highlights the changes that take place in the brain and behavior as a result of chronic using, and shares the surprising hidden gifts of personality that addiction can expose. She describes what drove her to addiction, what helped her recover, and her belief that a “cure” for addiction will not be found in our individual brains but in the way we interact with our communities. Set apart by its color, candor, and bell-clear writing, Never Enough is a revelatory look at the roles drugs play in all of our lives and offers crucial new insight into how we can solve the epidemic of abuse.

Drug Addiction and Drug Policy

Author : William N. Brownsberger
Publisher : Harvard University Press
ISBN 13 : 0674038622
Total Pages : 284 pages
Book Rating : 4.6/5 (74 download)

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Book Synopsis Drug Addiction and Drug Policy by : William N. Brownsberger

Download or read book Drug Addiction and Drug Policy written by William N. Brownsberger and published by Harvard University Press. This book was released on 2009-06-30 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the culmination of five years of debate among distinguished scholars in law, public policy, medicine, and biopsychology, about the most difficult questions in drug policy and the study of addictions. Do drug addicts have an illness, or is the addiction under their control? Should they be treated as patients or as criminals? Challenging the conventional wisdom, the authors show that these standard dichotomies are false.

The Molecular Basis of Drug Addiction

Author : Shafiqur Rahman
Publisher : Academic Press
ISBN 13 : 0128038683
Total Pages : 279 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis The Molecular Basis of Drug Addiction by : Shafiqur Rahman

Download or read book The Molecular Basis of Drug Addiction written by Shafiqur Rahman and published by Academic Press. This book was released on 2016-01-28 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Progress in Molecular Biology and Translational Science focuses on the molecular basis of drug addiction. Contains contributions from leading authorities Informs and updates on all the latest developments in the field

Drug Addiction

Author : Rao S. Rapaka
Publisher : Springer Science & Business Media
ISBN 13 : 0387766782
Total Pages : 791 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Drug Addiction by : Rao S. Rapaka

Download or read book Drug Addiction written by Rao S. Rapaka and published by Springer Science & Business Media. This book was released on 2008-06-19 with total page 791 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of physiological, biochemical, and genetic pathways underlying drug addiction, and resultant efforts to develop novel treatment strategies dealing with drug addiction and other CNS disorders where the neurophysiological processes overlap, such as treatment of pain. The volume focuses on the translation of fundamental addiction research to a variety of treatments and brings together scientists with wide ranging expertise.

The Addicted Brain

Author : Michael J. Kuhar
Publisher : FT Press
ISBN 13 : 0132542501
Total Pages : 237 pages
Book Rating : 4.1/5 (325 download)

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Book Synopsis The Addicted Brain by : Michael J. Kuhar

Download or read book The Addicted Brain written by Michael J. Kuhar and published by FT Press. This book was released on 2012 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The Addicted Brain" explains clearly and vividly what has been learned about how and why some people become addicted and abuse drugs or other substances, the relatively long-term changes these substances can make in the brain, and the progress being made on treatments.

Addiction

Author : David Nutt
Publisher : Oxford University Press, USA
ISBN 13 : 0199685703
Total Pages : 102 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis Addiction by : David Nutt

Download or read book Addiction written by David Nutt and published by Oxford University Press, USA. This book was released on 2013-09-26 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential reference for psychiatrists, clinical psychologists, trainees, and specialist nurses, as well as primary care physicians/GPs with a special interest in mental health conditions and other healthcare professionals.

Pathways of Addiction

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309055334
Total Pages : 330 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Pathways of Addiction by : Institute of Medicine

Download or read book Pathways of Addiction written by Institute of Medicine and published by National Academies Press. This book was released on 1996-11-01 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug abuse persists as one of the most costly and contentious problems on the nation's agenda. Pathways of Addiction meets the need for a clear and thoughtful national research agenda that will yield the greatest benefit from today's limited resources. The committee makes its recommendations within the public health framework and incorporates diverse fields of inquiry and a range of policy positions. It examines both the demand and supply aspects of drug abuse. Pathways of Addiction offers a fact-filled, highly readable examination of drug abuse issues in the United States, describing findings and outlining research needs in the areas of behavioral and neurobiological foundations of drug abuse. The book covers the epidemiology and etiology of drug abuse and discusses several of its most troubling health and social consequences, including HIV, violence, and harm to children. Pathways of Addiction looks at the efficacy of different prevention interventions and the many advances that have been made in treatment research in the past 20 years. The book also examines drug treatment in the criminal justice setting and the effectiveness of drug treatment under managed care. The committee advocates systematic study of the laws by which the nation attempts to control drug use and identifies the research questions most germane to public policy. Pathways of Addiction provides a strategic outline for wise investment of the nation's research resources in drug abuse. This comprehensive and accessible volume will have widespread relevanceâ€"to policymakers, researchers, research administrators, foundation decisionmakers, healthcare professionals, faculty and students, and concerned individuals.

The Effects of Drug Abuse on the Human Nervous System

Author : Bertha Madras
Publisher : Elsevier
ISBN 13 : 0124186858
Total Pages : 625 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis The Effects of Drug Abuse on the Human Nervous System by : Bertha Madras

Download or read book The Effects of Drug Abuse on the Human Nervous System written by Bertha Madras and published by Elsevier. This book was released on 2013-11-15 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug use and abuse continues to thrive in contemporary society worldwide and the instance and damage caused by addiction increases along with availability. The Effects of Drug Abuse on the Human Nervous System presents objective, state-of-the-art information on the impact of drug abuse on the human nervous system, with each chapter offering a specific focus on nicotine, alcohol, marijuana, cocaine, methamphetamine, MDMA, sedative-hypnotics, and designer drugs. Other chapters provide a context for drug use, with overviews of use and consequences, epidemiology and risk factors, genetics of use and treatment success, and strategies to screen populations and provide appropriate interventions. The book offers meaningful, relevant and timely information for scientists, health-care professionals and treatment providers. A comprehensive reference on the effects of drug addiction on the human nervous system Focuses on core drug addiction issues from nicotine, cocaine, methamphetamine, alcohol, and other commonly abused drugs Includes foundational science chapters on the biology of addiction Details challenges in diagnosis and treatment options

How Tobacco Smoke Causes Disease

Author :
Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis How Tobacco Smoke Causes Disease by :

Download or read book How Tobacco Smoke Causes Disease written by and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Drugs, Addiction, and the Brain

Author : George F. Koob
Publisher : Academic Press
ISBN 13 : 0123869595
Total Pages : 351 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Drugs, Addiction, and the Brain by : George F. Koob

Download or read book Drugs, Addiction, and the Brain written by George F. Koob and published by Academic Press. This book was released on 2014-07-12 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems in the brain that are responsible for drug addiction. Common neurobiological elements are emphasized that provide novel insights into how the brain mediates the acute rewarding effects of drugs of abuse and how it changes during the transition from initial drug use to compulsive drug use and addiction. The book provides a detailed overview of the pathophysiology of the disease. The information provided will be useful for neuroscientists in the field of addiction, drug abuse treatment providers, and undergraduate and postgraduate students who are interested in learning the diverse effects of drugs of abuse on the brain. Full-color circuitry diagrams of brain regions implicated in each stage of the addiction cycle Actual data figures from original sources illustrating key concepts and findings Introduction to basic neuropharmacology terms and concepts Introduction to numerous animal models used to study diverse aspects of drug use. Thorough review of extant work on the neurobiology of addiction

The Neurobiology of Addiction

Author : Trevor W. Robbins
Publisher :
ISBN 13 : 0199562156
Total Pages : 327 pages
Book Rating : 4.1/5 (995 download)

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Book Synopsis The Neurobiology of Addiction by : Trevor W. Robbins

Download or read book The Neurobiology of Addiction written by Trevor W. Robbins and published by . This book was released on 2010 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past two decades, there have been astonishing advances in our understanding of the neurobiological basis and nature of drug addiction. We now know the initial molecular sites of action, at identified receptors, of virtually all of the major drugs of abuse including cocaine, heroin, and amphetamine, as well as legal drugs such as nicotine and alcohol. We also understand the main components of a 'reward system' and its connections to major brain regions involved in motivation and emotion, such as the amygdala, hippocampus, and prefrontal cortex. The Neurobiology of Addiction describes the latest advances in our understanding of addiction. It brings together world class researchers to debate the nature and extent of addiction, as well as its causes, consequences, and treatment. The focus of the book is on the brain processes underlying addiction, in terms of neural systems, neurochemical basis, and molecular changes. Several types of addiction are discussed ranging from illicit drugs - cocaine, amphetamine, and heroin to legal drugs - alcohol and nicotine. In addition, it explores increasingly common behavioural addictions such as gambling and obesity. Included are chapters on vulnerability to addiction, genetic factors, opponent motivational processes, animal models, relapse, cognitive deficits associated with drug abuse, new pharmacological treatments, and current controversies concerning different neuropsychological theories of addiction. Throughout, it reports on cutting edge research using brain imaging, and state of the art molecular methodology. The book will make fascinating reading for students and teachers in the field of neuroscience, pharmacology and psychology, as well as experts in the field.