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Molecular Biology In Blood Transfusion
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Book Synopsis Molecular Biology in Blood Transfusion by : Cees Smit Sibinga
Download or read book Molecular Biology in Blood Transfusion written by Cees Smit Sibinga and published by Springer Science & Business Media. This book was released on 2000-09-30 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: The international symposia on blood transfusion in Groningen have taken place without interruption since 1976. Each year Dr. Smit-Sibinga and his team have not only organized a meeting on timely topics in blood transfusion, but also succeeded in attracting prominent chairmen and speakers. The subject of the 24th Symposium was Molecular Biology in Blood Transfusion and it was chaired by Dr. Harvey G. Klein, National Institutes of Health, USA. In this book of proceedings an extraordinary range of subjects is covered, including diagnostic aspects, virology, quality control, cell and protein processing as well as a section on new horizons in clinical medicine.
Book Synopsis Molecular Protocols in Transfusion Medicine by : Gregory A. Denomme
Download or read book Molecular Protocols in Transfusion Medicine written by Gregory A. Denomme and published by Elsevier. This book was released on 2000-04-27 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: This essential methods manual for immunohematologists (or hematologists and immunohematologists) provides information on genes that encode antigens on red blood cells, platelets and neutrophils. The book begins by covering general concepts in molecular biology and specific protocols such as DNA preparation, PCR-RFLP and allele-specific PCR. Information on the erythrocyte, platelet and neutrophil antigen systems and the molecular basis of polymorphisms are presented clearly in a gene facts sheet format. Database accession numbers and useful adjuncts such as Request forms, worksheets for PCR/enzyme digests also serve to benefit the user. The information is clearly presented and easily accessible and is complemented by the excellent diagrams and tabular material. This book is invaluable for both new and experienced researchers in the field and other related disciplines. - Essential for hematologists and those involoved in tissue typing and the study of human genetic polymorphisms - Presents clearly and concisely the information on a particular variant and the technique used to detect it - Organized by antigen and provides sequences of polymorphisms and primers - Details the general concepts and critical information on genes, their products, and sources of relevant nucleic acids - Includes protocols that allow investigators to set up assays with minimal effort (protocols include primers, reagents, reaction conditions, sizes of amplified products, restriction fragment digests, and the relevant safety information) - Provides information that helps interpret results in clinical settings - Contains additional sources of information (e.g., key references, web site addresses, glossary, Database accession numbers, request forms, and worksheets for PCR/enzyme digests)
Book Synopsis Applications of Molecular Biology to Blood Transfusion Medicine by : George Garratty
Download or read book Applications of Molecular Biology to Blood Transfusion Medicine written by George Garratty and published by American Association of Blood Banks (AABB). This book was released on 1997 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Applications of Molecular Biology to Blood Transfusion Medicine by : G. Garratly
Download or read book Applications of Molecular Biology to Blood Transfusion Medicine written by G. Garratly and published by S Karger Ag. This book was released on 1997-08-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Biotechnology in blood transfusion by : C.Th. Smit Sibinga
Download or read book Biotechnology in blood transfusion written by C.Th. Smit Sibinga and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: This symposium is devoted to Biotechnology in Blood Transfusion; there are 22 experts discussing the state of the art in the application of monoclonal anti bodies, recombinant DNA technologies and heterologous expression systems to the improvement and sometimes replacement of blood products, charac terization of blood constituents, and the effect of these developments on blood transfusion procedures. Ten and maybe five years ago the title of a symposium such as this would have been Biosciences in blood transfusion, informing what basic developments in molecular biology, biochemistry and human physiology might pertain to blood transfusion in the distant future. That future is getting closer, and not only one is interested in basic developments in immunology, recognition and identification of viral and bacterial components and products, tissue and blood bloodgroup blood group typing, typing, but also in the potential application of these developments and their economic perspectives. That is what biotechnology is all alI about: basic science telIs tells us where and how we might look for new technologies, and the development of such tech nologies is only possible if there is a perspective for improvement in quality, safety, acceptance or performance to cost ratio.
Book Synopsis Blood Banking and Transfusion Medicine by : Christopher D. Hillyer
Download or read book Blood Banking and Transfusion Medicine written by Christopher D. Hillyer and published by Elsevier Health Sciences. This book was released on 2006-10-18 with total page 910 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ever since the discovery of blood types early in the last century, transfusion medicine has evolved at a breakneck pace. This second edition of Blood Banking and Transfusion Medicine is exactly what you need to keep up. It combines scientific foundations with today's most practical approaches to the specialty. From blood collection and storage to testing and transfusing blood components, and finally cellular engineering, you'll find coverage here that's second to none. New advances in molecular genetics and the scientific mechanisms underlying the field are also covered, with an emphasis on the clinical implications for treatment. Whether you're new to the field or an old pro, this book belongs in your reference library. Integrates scientific foundations with clinical relevance to more clearly explain the science and its application to clinical practice. Highlights advances in the use of blood products and new methods of disease treatment while providing the most up-to-date information on these fast-moving topics Discusses current clinical controversies, providing an arena for the discussion of sensitive topics. Covers the constantly changing approaches to stem cell transplantation and brings you the latest information on this controversial topic.
Book Synopsis Blood Groups and Red Cell Antigens by : Laura Dean
Download or read book Blood Groups and Red Cell Antigens written by Laura Dean and published by . This book was released on 2005 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis BeadChip Molecular Immunohematology by : JoAnn M. Moulds
Download or read book BeadChip Molecular Immunohematology written by JoAnn M. Moulds and published by Springer Science & Business Media. This book was released on 2010-11-25 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text is a review of molecular immunohematology (MI). It draws from analyses and case studies around the world and details many techniques used in many labs. It is aimed at anyone interested in how MI is changing blood bank and transfusion medicine.
Book Synopsis Immunology and Blood Transfusion by : C.Th. Smit Sibinga
Download or read book Immunology and Blood Transfusion written by C.Th. Smit Sibinga and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: In transfusion medicine the scientific fundamentals of immunology have had a considerable clinical impact. Transfusion may suppress the immunity but some patients could suffer disadvantages including GvHD, alloimmunisation and possible cancer, where white cells (WBC) play pivotal roles in this phenomenon, presenting antigens and producing cytokines. A clinical application of this practice is LAK-cells targeted against cancer. MHC on the WBC may provide additional immunological modulations through series of secondary messengers. Thus reduction of WBC in the blood and bone marrow may be advantageous for patients. On the other hand, sharing a part of MHC or making the transplanted white cells anergic by storage may be even more advantageous for patients. CMV infection could mimic part of this MHC. UV radiation is effective in the inactivation of the WBC although filters are easy means for such removal. However, their accurate quantification requires flow cytometry that has considerable potential application in blood transfusions. Idiotypic antibody could play an important role in platelet theory. However, the potential infection risks in transfusion like HIV and HCV remain, but application of molecular biological methods like PCR or RT/PCR has great potentials in detection of infectious diseases, transplantation and genetic disorders. Immuno affinity purified concentrates, like factor IX and protein C, could reduce patients' immune functions, where in the future protein C could be derived from transgenic animals. Advances are sure to emerge through adoptive immunotherapy and gene therapies are exciting prospects when genes transferred into lymphocytes could be used to correct cell mediated immune deficiency, as in ADA.
Book Synopsis White cells and platelets in blood transfusion by : C.Th. Smit Sibinga
Download or read book White cells and platelets in blood transfusion written by C.Th. Smit Sibinga and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a clinical discipline blood transfusion encompasses enormous vista, vary ing from biotechnology to molecular biology, from plasma products, cell biology and growth factors to interleukines. Growth of knowledge in this field has been rapid, and expertise is now required to be mastered and renewed in translating these ideas for patient care. Various types of cells could be harvested - progenitor stem cells derived from bone marrow or from circulating blood as a source for transplants; in the hemostatic armoury platelets could be used prophylactically; granulocytes and mononuclear cells are available for treatment of infections or immune modulations. However, their therapeutic use carries potential complications including graft versus host disease and CMV-infection. Prevention of such complications by irradiation and by removal of immunocompetent leukocytes are important issues. Thus, production of such therapeutic materials ought to address the issues at the earliest, to eliminate those problems while adhering to the con cept of high quality; the impact of storing platelets for longer periods by using improved plastic containers or storing almost indefinitely in frozen state should be explored. Rapid progress in cell culture techniques and bio technology have enriched the transfusion medicine armoury with lympho kines, interferons and cell colony growth factors which have great potentials for enhancement of basic knowledge as well as considerable therapeutic applications in patients.
Book Synopsis Essential Guide to Blood Groups by : Geoff Daniels
Download or read book Essential Guide to Blood Groups written by Geoff Daniels and published by John Wiley & Sons. This book was released on 2013-08-29 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential Guide to Blood Groups is the only pocket sized guide to provide essential information on blood group systems. The main aim of the blood transfusion laboratory is to promote safe blood transfusion. The avoidance of errors, from sample receipt and laboratory testing through to the release of blood for transfusion, is of paramount importance. Knowledge of immunohaematology theory and its application to blood transfusion together with the principles of good laboratory practice are essential. This handbook helps to address these important issues and also covers: • the serology, inheritance, biochemistry, and molecular genetics of the most important blood group systems • their clinical importance • techniques used in blood grouping, troubleshooting, and quality assurance This unique and practical guide: • is written by leaders in the field, including the author of the best seller Human Blood Groups • provides the basic knowledge of blood groups needed by all those working in the important fields of transfusion medicine and science. • helps in resolving commonly encountered problems Essential Guide to Blood Groups will be valuable for undergraduate medical laboratory scientists and for postgraduate scientists and medical practitioners training to specialise in transfusion and transplantation. As a pocket edition, it will also be a useful addition to other reference works on blood groups for quick access to information for medical practitioners and in red cell immunohaematology laboratories.
Book Synopsis Human Blood Groups by : Geoff Daniels
Download or read book Human Blood Groups written by Geoff Daniels and published by John Wiley & Sons. This book was released on 2013-01-16 with total page 950 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Blood Groups is a comprehensive and fully referenced text covering both the scientific and clinical aspects of red cell surface antigens, including: serology, inheritance, biochemistry, molecular genetics, biological functions and clinical significance in transfusion medicine. Since the last edition, seven new blood group systems and over 60 new blood group antigens have been identified. All of the genes representing those systems have now been cloned and sequenced. This essential new information has made the launch of a third edition of Human Blood Groups, now in four colour, particularly timely. This book continues to be an essential reference source for all those who require clinical information on blood groups and antibodies in transfusion medicine and blood banking.
Book Synopsis Introduction to Molecular Immunohematology by : Tony S. Casina
Download or read book Introduction to Molecular Immunohematology written by Tony S. Casina and published by . This book was released on 2020 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "The book will be an approachable guide to learning about molecular testing as it relates to blood banking and Immunohematology. Methods will be discussed, allele tables explained, and nuances taught, so that the reader will feel comfortable understanding and using the resources that are available. It will be a useful tool to the SBB student or pathology resident studying for exams"--Provided by publisher.
Book Synopsis Modern Blood Banking and Transfusion Practices by : Denise Harmening
Download or read book Modern Blood Banking and Transfusion Practices written by Denise Harmening and published by F.A. Davis. This book was released on 2018-11-30 with total page 1475 pages. Available in PDF, EPUB and Kindle. Book excerpt: Join the generations of students who have embarked on successful careers with a firm foundation in the theory and practice of blood banking and transfusion practices. Denise Harmening’s classic text teaches you not only how to perform must-know tests and tasks, but to understand the scientific principles behind them. You’ll begin with a review of the basic concepts of red blood cell and platelet preservation, genetics, immunology, and molecular biology. Then you’ll move to the hows and whys of clinical practice. And, you’ll be prepared for new advances in the field.
Book Synopsis Screening Donated Blood for Transfusion-transmissible Infections by : World Health Organization
Download or read book Screening Donated Blood for Transfusion-transmissible Infections written by World Health Organization and published by World Health Organization. This book was released on 2010 with total page 73 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Blood transfusion is a life-saving intervention that has an essential role in patient management within health care systems. All Member States of the World Health Organization (WHO) endorsed World Health Assembly resolutions WHA28.72 (1) in 1975 and WHA58.13 (2) in 2005. These commit them to the provision of adequate supplies of safe blood and blood products that are accessible to all patients who require transfusion either to save their lives or promote their continuing or improving health." --Preface.
Book Synopsis Cryopreservation and low temperature biology in blood transfusion by : C.Th. Smit Sibinga
Download or read book Cryopreservation and low temperature biology in blood transfusion written by C.Th. Smit Sibinga and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: The theme of this 14th International Symposium on Blood Transfusion is closely related to the work and scientific contributions of the Dutch cryobiology pioneer Dr. Herman W. Krijnen of the Dutch Red Cross Central Laboratory. Dr. Krijnen was known and respected in the national and interna tional blood transfusion community as an extremely competent scientist and a beloved and admired colleague. Dr. Krijnen was intentionally honoured with the invitation to open this symposium on cryopreservation and low temperature biology in blood transfusion and be the guest of honour at this event. Unfortunately, Dr. Krijnen suddenly died on the first of June 1989. In honour and mem ory of Dr. Krijnen this symposium will therefore be dedicated to him. Since the lOth International Symposium on Blood Transfusion in 1985 highlighted the theme of "Future developments in blood banking", major changes have occurred in the blood banking world. Most of these changes were forced upon the Blood Banks by the fear of spreading AIDS through contaminated donations. This not only led to the wide spread testing of blood, but also to a more appropriate counselling of the community and the blood donors in specific. Additionally, virus inacti vation techniques were introduced for those components derived from multiple donations and intended for a regular transfusion in haemophi lia patients and others.
Book Synopsis The Blood Group Antigen FactsBook by : Marion E. Reid
Download or read book The Blood Group Antigen FactsBook written by Marion E. Reid and published by Academic Press. This book was released on 2012-11-07 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Blood Group Antigen FactsBook has been an essential resource in the hematology, transfusion and immunogenetics fields since its first publication in the late 1990s.The third edition of The Blood Group Antigen FactsBook has been completely revised, updated and expanded to cover all 32 blood group systems. It blends scientific background and clinical applications and provides busy researchers and clinicians with at-a-glance information on over 330 blood group antigens, including history and information on terminology, expression, chromosomal assignment, carrier molecular description, functions, molecular bases of antigens and phenotypes, effect of enzymes/chemicals, clinical significance, disease associations and key references. Includes over 330 entries on blood group antigens in individual factsheetsOffers a logical and concise catalogue structure for each antigen in an improved interior design for quick reference. Written by 3 international experts from the field of immunohematology and transfusion medicine.
