Molecular Basis of Reproductive Endocrinology

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Publisher : Springer Science & Business Media
ISBN 13 : 1461392608
Total Pages : 412 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Molecular Basis of Reproductive Endocrinology by : Peter C.K. Leung

Download or read book Molecular Basis of Reproductive Endocrinology written by Peter C.K. Leung and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in molecular biology have provided new dimensions in the study of the reproductive system. There has been major progress in our understanding of the molecular mechanisms of hormone action in the past few' years. The symposium on "Molecular Basis of Reproductive Endocrinology" was organized to highlight new research findings on the regulation of the hypothalamic-pituitary-gonadal axis. The emphasis of the symposium was on physiological questions answered by the molecular biology approach. Studies on the functional relevance of gonadotropin releasing hormone and LH and FSH gene expression were presented, together with research on the molecular biology of ovarian and testicular steroidogenic enzymes and protein hormones. Also, several novel aspects of hormone gene expression in placental tissues were reviewed. The symposium was held July 25 to 26, 1991, immediately prior to the 24th Annual Meeting of the Society for the Study of Reproduction, on the campus of the University of British Columbia in Vancouver. Serono Symposia, USA generously financed and coordinated the meeting. We are indebted to Dr. Bruce K. Burnett and Dr. L. Lisa Kern for their professional assistance in the organization of the symposium. We would also like to thank Drs. Victor Gomel, Basil Ho Yuen, and John Challis, who served as session moderators. Most of all, we truly appreciate the efforts of all the invited speakers, poster presenters, and discussants in making this a memorable event as the largest one-day meeting of the Serono Symposia USA, series.

Molecular Basis of Reproductive Endocrinology

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Author :
Publisher : Springer
ISBN 13 : 9780387978611
Total Pages : 311 pages
Book Rating : 4.9/5 (786 download)

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Book Synopsis Molecular Basis of Reproductive Endocrinology by : Peter C.K. Leung

Download or read book Molecular Basis of Reproductive Endocrinology written by Peter C.K. Leung and published by Springer. This book was released on 1992-12-18 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in molecular biology have provided new dimensions in the study of the reproductive system. There has been major progress in our understanding of the molecular mechanisms of hormone action in the past few' years. The symposium on "Molecular Basis of Reproductive Endocrinology" was organized to highlight new research findings on the regulation of the hypothalamic-pituitary-gonadal axis. The emphasis of the symposium was on physiological questions answered by the molecular biology approach. Studies on the functional relevance of gonadotropin releasing hormone and LH and FSH gene expression were presented, together with research on the molecular biology of ovarian and testicular steroidogenic enzymes and protein hormones. Also, several novel aspects of hormone gene expression in placental tissues were reviewed. The symposium was held July 25 to 26, 1991, immediately prior to the 24th Annual Meeting of the Society for the Study of Reproduction, on the campus of the University of British Columbia in Vancouver. Serono Symposia, USA generously financed and coordinated the meeting. We are indebted to Dr. Bruce K. Burnett and Dr. L. Lisa Kern for their professional assistance in the organization of the symposium. We would also like to thank Drs. Victor Gomel, Basil Ho Yuen, and John Challis, who served as session moderators. Most of all, we truly appreciate the efforts of all the invited speakers, poster presenters, and discussants in making this a memorable event as the largest one-day meeting of the Serono Symposia USA, series.

Reproductive Endocrinology

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Publisher : Springer Science & Business Media
ISBN 13 : 0387881867
Total Pages : 355 pages
Book Rating : 4.3/5 (878 download)

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Book Synopsis Reproductive Endocrinology by : P. Jorge Chedrese

Download or read book Reproductive Endocrinology written by P. Jorge Chedrese and published by Springer Science & Business Media. This book was released on 2009-06-13 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular biology emerged from advances in biochemistry during the 1940s and 1950s, when the structure of the nucleic acids and proteins were elucidated. Beginning in the 1970s, with nucleic acid enzymology and the discovery of the restriction enzymes, the tools of molecular biology became widely available and applied in cell biology to study how genes are regulated. This new knowledge impacted endocrinology and reproductive biology since it was largely known that the secretion of the internal glands affected the phenotypes, and expression of genes. Modern reproductive biology encompasses every level of biological study from genomics to ecology, encompassing cell biology, biochemistry, endocrinology and general physiology. All of these disciplines require a basic knowledge, both as a tool and as an essential aid to a fundamental understanding of the principles of life in health and disease. Overall, molecular biology is central to scientific studies in all living matter, impacting disciplines such as medicine, related health sciences, veterinary, agriculture and environmental sciences. In this book, the basic biochemistry of nucleic acids and proteins are reviewed. Methodologies used to study signaling and gene regulation in the endocrine/reproductive system are also discussed. Topics include mechanisms of hormone action and several endocrine disorders affecting the reproductive system. Professionals in the medical, veterinary and animal sciences fields will find exciting and stimulating material enhancing the breadth and quality of their research.

Molecular Biology in Reproductive Medicine

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Author :
Publisher : CRC Press
ISBN 13 : 9781850709947
Total Pages : 540 pages
Book Rating : 4.7/5 (99 download)

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Book Synopsis Molecular Biology in Reproductive Medicine by : Bart C.J.M. Fauser

Download or read book Molecular Biology in Reproductive Medicine written by Bart C.J.M. Fauser and published by CRC Press. This book was released on 1999-04-26 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an exceptionally comprehensive, color-illustrated clinical reference work of great authority thoroughly covering the basic science and clinical applications of molecular biology in reproductive medicine. It is written clearly and definitively for practicing physicians needing a reader-friendly textbook on this new and important area of clinical practice. Its noted authors are among the world s leading experts in molecular and cell biology, pharmacology, human and clinical genetics, obstetrics and gynecology and women's health, reproductive endocrinology and fertility, physiology, and medical ethics. The book contains 23 chapters in six sections on molecular genetics, cell biology, hormone syntheses and action and signal transduction, gamete and embryo biology, clinical genetics, and the genetics of female and male reproductive dysfunction.

Yen & Jaffe's Reproductive Endocrinology E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 1455759724
Total Pages : 1232 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Yen & Jaffe's Reproductive Endocrinology E-Book by : Jerome F. Strauss

Download or read book Yen & Jaffe's Reproductive Endocrinology E-Book written by Jerome F. Strauss and published by Elsevier Health Sciences. This book was released on 2013-08-28 with total page 1232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Yen & Jaffe’s Reproductive Endocrinology helps you successfully diagnose and manage the spectrum of female and male reproductive system diseases, from impaired fertility, infertility, and recurrent pregnancy loss through problems of sexual development, puberty, menstrual disturbances, fibroids, endometriosis, and reproductive aging. This trusted endocrinology reference book is ideal for studying or as a quick reference when making daily diagnostic and therapeutic decisions, ensuring it's just the resource you need to offer your patients the best possible care. Apply the latest reproductive endocrinology advances in basic and clinical science, including molecular, cellular, and genetic concepts, and grasp their relevance to pathophysiology, diagnosis, and therapy. Maximize fertility in women and men undergoing chemotherapy and other cancer treatments, and counsel patients on environmental factors affecting reproduction. Stay on top of recent developments including the impact of obesity on fertility; ovarian tissue banking; cryopreservation; pre-implantation genetic diagnosis; ovulation induction; and risks and treatments for steroid hormone-responsive cancers. View basic anatomic structures, endocrine processes, and cell function and dysfunction with absolute clarity through full-color illustrations and new images throughout. Confidently perform procedures through expanded coverage of reproductive and infertility surgery. Apply the latest reproductive endocrinology advances in basic and clinical science, including molecular, cellular, and genetic concepts, and grasp their relevance to pathophysiology, diagnosis, and therapy. Maximize fertility in women and men undergoing chemotherapy and other cancer treatments, and counsel patients on environmental factors affecting reproduction. Stay on top of recent developments including the impact of obesity on fertility; ovarian tissue banking; cryopreservation; pre-implantation genetic diagnosis; ovulation induction; and risks and treatments for steroid hormone-responsive cancers. View basic anatomic structures, endocrine processes, and cell function and dysfunction with absolute clarity through full-color illustrations and new images throughout.

Yen & Jaffe's Reproductive Endocrinology

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 145572758X
Total Pages : 1232 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Yen & Jaffe's Reproductive Endocrinology by : Jerome F. Strauss, III MD, PhD

Download or read book Yen & Jaffe's Reproductive Endocrinology written by Jerome F. Strauss, III MD, PhD and published by Elsevier Health Sciences. This book was released on 2013-09-13 with total page 1232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Yen Jaffe's Reproductive Endocrinology helps you successfully diagnose and manage the spectrum of female and male reproductive system diseases, from impaired fertility, infertility, and recurrent pregnancy loss through problems of sexual development, puberty, menstrual disturbances, fibroids, endometriosis, and reproductive aging. This trusted endocrinology reference book is ideal for fellows, endocrinologists, or as a quick reference when making daily diagnostic and therapeutic decisions. It is just the resource you need to offer your patients the best possible reproductive care. "This new edition helps the reader to stay on top of recent developments. It is a must for subspecialists in reproductive medicine and a valuable source of information in the library of any department and clinical unit involved in reproductive medicine." Reviewed by Acta Obstetricia et Gynecologica Scandinavica February 2015 "It is a must for subspecialists in reproductive medicine and a valuable source of information in the library of any department and clinical unit involved in reproductive medicine." Reviewed by Acta Obstetricia et Gynecologica Scandinavica , March 2015 Get unmatched guidance you can trust, such as fresh insights into today's field and future advances, through the knowledge gleaned from worldwide fertility experts in reproductive medicine. Further your study of Reproductive Endocrinology with a list of suggested readings at the end of each chapter. Conveniently access the fully searchable text and view all of the images online at Expert Consult. Apply the latest reproductive endocrinology advances in basic and clinical science, including molecular, cellular, and genetic concepts, and grasp their relevance to pathophysiology, diagnosis, and therapy. Maximize fertility in women and men undergoing chemotherapy and other cancer treatments, and counsel patients on environmental factors affecting reproduction. Stay on top of recent developments including the impact of obesity on fertility; ovarian tissue banking; cryopreservation; pre-implantation genetic diagnosis; ovulation induction; and risks and treatments for steroid hormone-responsive cancers. View basic anatomic structures, endocrine processes, and cell function and dysfunction with absolute clarity through full-color illustrations and new images throughout. Confidently perform procedures through expanded coverage of reproductive and infertility surgery and online videos demonstrating key techniques.

Yen & Jaffe's Reproductive Endocrinology E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 032358232X
Total Pages : 1379 pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis Yen & Jaffe's Reproductive Endocrinology E-Book by : Jerome F. Strauss

Download or read book Yen & Jaffe's Reproductive Endocrinology E-Book written by Jerome F. Strauss and published by Elsevier Health Sciences. This book was released on 2017-12-23 with total page 1379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now celebrating its 40th anniversary, Yen & Jaffe's Reproductive Endocrinology, 8th Edition, by Drs. Jerome F. Strauss III, Robert L. Barbieri, and Antonio R. Gargiulo, keeps you up to date with the latest information on the diagnosis and management of the full range of female and male reproductive disorders. This cornerstone text thoroughly covers both basic science and clinical practice, making it a one-stop reference for all reproductive issues, including impaired fertility, infertility, recurrent pregnancy loss, problems of sexual development, menstrual disturbances, fibroids, endometriosis, female and male reproductive aging, fertility preservation, assisted reproduction technologies including ovarian stimulation and ovulation induction, transgender hormonal treatment, and contraception. Every chapter has been completely revised and updated to reflect important changes in this fast-moving field. - Covers key topics such as the role of genetics in reproductive endocrinology, environmental factors in reproductive endocrinology, and recent advances in surgical procedures. - Features full-color, high-quality illustrations that clearly depict basic anatomic structures, endocrine processes, and cell function and dysfunction. - Provides the knowledge and expertise of global experts who draw on the latest developments in the field to keep you abreast of current science and practice in endocrinology. Coverage includes molecular, cellular, and genetic concepts and their relevance to pathophysiology, diagnosis, and therapy. - Features new bulleted lists under major headings in each chapter for quick, at-a-glance summaries of every section. - Includes a new online video library that highlights surgical procedures, diagnostic imaging, and functional ultrasound imaging. Videos cover Disorders of Sex Development, Endometriosis, Benign Uterine Disorders, Gamete and Embryo Manipulation, and Fertility Preservation. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Reproductive Endocrinology and Biology

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Author :
Publisher : Elsevier
ISBN 13 : 0080544584
Total Pages : 355 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Reproductive Endocrinology and Biology by : Edward Bittar

Download or read book Reproductive Endocrinology and Biology written by Edward Bittar and published by Elsevier. This book was released on 1998-07-27 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: We have now reached the mid-point of our editorial task of putting together the compendium, Principles of Medical Biology, which is supposed to be composed of twenty-five modules. The present single-volume module on reproductive endocrinology and biology is in more than one respect a continuation of Module 10 (in two volumes) dealing with molecular and cellular endocrinology. In addition, it intersects, as it should, with various parts of obstetrics and gynaecology, both of which are abetted by technology. One has only to recall that the practical benefits of ultrasound in perinatal medicine and in vitro fertilisation are the outcome of the technological revolution in biomedicine. Whether we are approaching a new era in reproductive biology following the invention of animal cloning is still hard to tell. For some people, it remains an article of faith that cloning of the human being is highly probable. For others, asexual reproduction is anathema. It should surely be obvious to us all that somatic cell nuclear transfer technology (SCNTT) is going to be at its strongest in dealing with husbandry. Whether this and several social forces will alter our modern outlook, there can be little doubt.As in diverse clinical and basic research, so in obstetrics, animals are used as a model. The data thus obtained is extrapolated, if valid, to the mother and foetus. The success of this approach is exemplified in studies carried out on sheep as a model. On the whole, it is also quite apparent that progress in the field of reproductive biology is to a large extent ascribable to the discovery in other disciplines of new hormones, as well as the introduction of new tools and recent improvements in laboratory methods including measurement of hormones.

Molecular Biology of the Cell

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Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Polycystic Ovary Syndrome

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Publisher : Cambridge University Press
ISBN 13 : 9780521660730
Total Pages : 240 pages
Book Rating : 4.6/5 (67 download)

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Book Synopsis Polycystic Ovary Syndrome by : Gabor T. Kovacs

Download or read book Polycystic Ovary Syndrome written by Gabor T. Kovacs and published by Cambridge University Press. This book was released on 2000-07-20 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polycystic ovary syndrome (PCO) is one of the most common reproductive health problems of women. However, its effective treatment remains a significant challenge to the medical profession. This new publication provides an essential guide to the diagnosis of the syndrome, its etiology, pathology, and effective medical management. An important theme throughout the book is the role of PCO as a major cause of infertility, and the use of new assisted reproductive technologies to overcome this problem. In addition, this comprehensive account summarizes the most recent advances in the molecular basis of the syndrome, its genetic basis, and long-term health effects. Given the significant new developments in all these areas, this up-to-date account is the definitive guide to effective clinical practice in an area where consensus has previously been lacking. It will appeal to all doctors with an interest in reproductive endocrinology, including gynecologists, IVF specialists, and obstetricians.

Genetics of Human Infertility

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Author :
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318060984
Total Pages : 190 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Genetics of Human Infertility by : P.H. Vogt

Download or read book Genetics of Human Infertility written by P.H. Vogt and published by Karger Medical and Scientific Publishers. This book was released on 2017-09-12 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infertility affects more than one in ten couples worldwide and is related to highly heterogeneous pathologies sometimes only discernible in the germ line. Its complex etiology often, but not always, includes genetic factors besides anatomical defects, immunological interference, and environmental aspects. Nearly 30% of infertility cases are probably caused only by genetic defects. Thereby experimental animal knockout models convincingly show that infertility can be caused by single or multiple gene defects. Translating those basic research findings into clinical studies is challenging, leaving genetic causes for the vast majority of infertility patients unexplained. Nevertheless, a large number of candidate genes have been revealed by sophisticated molecular methods. This book provides a comprehensive overview on the subject of infertility written by the leading authorities in this field. It covers topics including basic biological, cytological, and molecular studies, as well as common and uncommon syndromes. It is a must-read for human geneticists, endocrinologists, epidemiologists, zoologists, and counsellors in human genetics, infertility, and assisted reproduction.

Recent updates in molecular Endocrinology and Reproductive Physiology of Fish

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Author :
Publisher : Springer
ISBN 13 : 9789811583711
Total Pages : 0 pages
Book Rating : 4.5/5 (837 download)

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Book Synopsis Recent updates in molecular Endocrinology and Reproductive Physiology of Fish by : Jitendra Kumar Sundaray

Download or read book Recent updates in molecular Endocrinology and Reproductive Physiology of Fish written by Jitendra Kumar Sundaray and published by Springer. This book was released on 2022-01-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is dedicated to present different aspects of reproductive physiology and molecular endocrinology of commercially important as well as potential aquaculture fish species. The existing aquaculture generation is looking for species diversification for efficient utilization of available diverse water resources. The knowledge of reproductive physiology of fish will help in development of breeding strategy for use in commercial aquaculture. Reproductive system is highly coordinated and governed by means of complex network of nervous, endocrine system and environmental factor as well. This book emphasize on different key aspects of reproductive endocrine system such as basic gonadal biology in the events of climate vulnerability, sex determination, sex reversal, stimulatory hormones, inhibitory hormones and receptors, environmental and chemical factor guiding reproduction, puberty, neuroendocrine regulation of reproduction etc. This book further describes how reproduction is not just indispensable for the existence or survival of an individual, but it is important for the survival of species. Chapters also address the concerns of anthropogenic activities on fish and the aquatic environment lead main trouble on physiological and reproductive processes of aquatic animals. This book offers an attractive compilation of highly relevant aspects of current and future of aquaculture, especially in view of the growing awareness of aquaculture, to food scientists working on commercial fish, animal biologists, fish geneticists etc. This book is very timely, and relevant to the sustainable development goals. The contents would be relevant to policy makers, working towards blue revolution and blue economy.

Speroff's Clinical Gynecologic Endocrinology and Infertility

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Author :
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1496350758
Total Pages : 1488 pages
Book Rating : 4.4/5 (963 download)

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Book Synopsis Speroff's Clinical Gynecologic Endocrinology and Infertility by : Hugh S. Taylor

Download or read book Speroff's Clinical Gynecologic Endocrinology and Infertility written by Hugh S. Taylor and published by Lippincott Williams & Wilkins. This book was released on 2019-07-11 with total page 1488 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the world's most widely read gynecology texts for nearly 50 years, Speroff ’s Clinical Gynecologic Endocrinology and Infertility provides a complete explanation of the female endocrine system and offers practical guidance for evaluation and treatment of common disorders. In this fully revised ninth edition, the editorial and author team from Yale School of Medicine have assumed the reins of Dr. Speroff’s landmark work, retaining the clear, concise writing style and illustrations that clarify and explain complex concepts. This classic text remains indispensable for students, residents, and clinicians working in reproductive endocrinology and infertility, bringing readers up to date with recent advances that have occurred in this fast-changing field.

Endocrine and Reproductive Physiology E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 032359574X
Total Pages : 288 pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis Endocrine and Reproductive Physiology E-Book by : Bruce White

Download or read book Endocrine and Reproductive Physiology E-Book written by Bruce White and published by Elsevier Health Sciences. This book was released on 2018-10-05 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Helps you easily master the material in a systems-based curriculum with learning objectives, Clinical Concept boxes, highlighted key words and concepts, chapter summaries, self-study questions, and a comprehensive exam. Includes nearly 200 clear, 2-color diagrams that simplify complex concepts. Features clinical commentaries that show you how to apply what you've learned to real-life clinical situations. Keeps you current with recent advances in endocrine physiology with expanded material on reproductive endocrinology and metabolism, and many updates at the molecular and cellular level. Covers the latest developments in fertilization, pregnancy, and lactation, as well as fetal development, puberty, and the decline of reproductive function with age. Complete the Mosby Physiology Series! Systems-based and portable, these titles are ideal for integrated programs. Blaustein, Kao, & Matteson: Cellular Physiology and Neurophysiology Johnson: Gastrointestinal Physiology Koeppen & Stanton: Renal Physiology Cloutier: Respiratory Physiology Pappano & Weir: Cardiovascular Physiology Hudnall: Hematology: A Pathophysiologic Approach

Clinical Gynecology

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Publisher : Cambridge University Press
ISBN 13 : 1107040396
Total Pages : 1127 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Clinical Gynecology by : Eric J. Bieber

Download or read book Clinical Gynecology written by Eric J. Bieber and published by Cambridge University Press. This book was released on 2015-04-23 with total page 1127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings.

Textbook of Clinical Embryology

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Publisher : Cambridge University Press
ISBN 13 : 110727625X
Total Pages : 408 pages
Book Rating : 4.1/5 (72 download)

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Book Synopsis Textbook of Clinical Embryology by : Kevin Coward

Download or read book Textbook of Clinical Embryology written by Kevin Coward and published by Cambridge University Press. This book was released on 2013-10-31 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: The success of Assisted Reproductive Technology is critically dependent upon the use of well optimized protocols, based upon sound scientific reasoning, empirical observations and evidence of clinical efficacy. Recently, the treatment of infertility has experienced a revolution, with the routine adoption of increasingly specialized molecular biological techniques and advanced methods for the manipulation of gametes and embryos. This textbook – inspired by the postgraduate degree program at the University of Oxford – guides students through the multidisciplinary syllabus essential to ART laboratory practice, from basic culture techniques and micromanipulation to laboratory management and quality assurance, and from endocrinology to molecular biology and research methods. Written for all levels of IVF practitioners, reproductive biologists and technologists involved in human reproductive science, it can be used as a reference manual for all IVF labs and as a textbook by undergraduates, advanced students, scientists and professionals involved in gamete, embryo or stem cell biology.

GnRH: The Master Molecule of Reproduction

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1475735650
Total Pages : 338 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis GnRH: The Master Molecule of Reproduction by : Andrea C. Gore

Download or read book GnRH: The Master Molecule of Reproduction written by Andrea C. Gore and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gonadotropin-releasing hormone (GnRH) cells are the key regulators of reproductive function in all vertebrate organisms. The GnRH molecule is synthesized in a small number of neurons in rostral hypothalamic regions of the brain. In mammals, these neurons release the GnRH decapeptide into the portal capillary system leading to the anterior pituitary gland. There, GnRH causes the release of the gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn act upon the gonads to stimulate their maturation, and to cause synthesis of sex steroid hormones, estrogen, progesterone and testosterone. Although each of the levels of the hypothalamic-pituitary-gonadal axis is critical for reproductive function, GnRH neurons play the primary role in the control of reproductive maturation and adult reproductive function, and may even play a role in reproductive senescence. Since its discovery in 1970, there has been intense interest in GnRH-producing neurons, with more than 8000 papers and chapters in the last decade alone. Despite this activity of research in basic and clinical science, there has never been a book written specifically on GnRH neurons. GnRH: The Master Molecule of Reproduction aims to bring together the large and diverse literature of both laboratory and applied research that focuses on these unique cells. This book will provide basic background into reproductive neuroendocrinology, as well as specifics regarding the role of GnRH neurons in the control of reproduction. Students studying endocrinology, reproduction, neuroendocrinology or molecular endocrinology will benefit from this book. In addition, this book will take a multi-species approach which will be useful both to basic researchers as well as clinicians. Whenever possible, species differences and similarities will be presented, and if possible, studies on humans, or the clinical relevance of basic research findings to humans will be discussed (such as the treatment of reproductive disorders such as abnormalities in pubertal development, or infertility).