Molecular and Cell Biology of Pain

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Author :
Publisher : Academic Press
ISBN 13 : 0128014326
Total Pages : 663 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Molecular and Cell Biology of Pain by :

Download or read book Molecular and Cell Biology of Pain written by and published by Academic Press. This book was released on 2015-03-02 with total page 663 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pain is the number one reason that people seek medical attention but pain is still under- and poorly-treated world-wide. The purpose of this book is to give an up to date picture of what causes pain, how pain becomes chronic and what pharmacological targets might be manipulated to alleviate acute and chronic pain. The book will cover a wide array of topics from gene polymorphisms to voltage-gated ion channels moving from cellular biology to whole animal physiology. Written by future leaders in the pain field Covers a wide range of targets Contains provocative ideas about the future direction of the pain field.

The Neurobiology of Pain

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Author :
Publisher : Molecular and Cellular Neurobi
ISBN 13 : 9780198515616
Total Pages : 422 pages
Book Rating : 4.5/5 (156 download)

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Book Synopsis The Neurobiology of Pain by : Stephen P. Hunt

Download or read book The Neurobiology of Pain written by Stephen P. Hunt and published by Molecular and Cellular Neurobi. This book was released on 2005 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last decade has seen major advances in the neurobiology of pain, primarily resulting from a deeper understanding of the way in which pain signals are coded and processed in the nervous system. This volume in the Molecular and Cellular Neurobiology is the first book for many years to present an integrated overview of the current state of research into the neurobiology of chronic and acute pain. While recent molecular aspects of nociception are covered in some detail, the book also emphasises the importance of viewing the pain experience as the co-ordinated response of many different areas of the nervous system. The molecular advances are set in the context of the neurobiological system of pain processing. The appropriate behavioural response to injury can therefore be thought of as the result of the integration of information processed within areas of the brain concerned with cognition, affect, sensory discrimination and movement. Chapters cover recent advances in nociceptor transduction mechanisms, nociceptor plasticity and the biochemical anatomy of pain pathways. Other contributions are concerned with the development of pain systems and with the central processing of nociceptive information studied with brain imaging techniques. Several chapters additionally cover the mechanisms of clinically important pain states such as neuropathic pain, cancer related pain and migraine. A new volume in the Molecular and Cellular Neurobiology series, this volume presents a state-of-the-art account of the neurobiological basis of pain, edited and written by the leading scientists in this field.

The Brain and Pain

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Publisher : Columbia University Press
ISBN 13 : 0231555717
Total Pages : 287 pages
Book Rating : 4.2/5 (315 download)

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Book Synopsis The Brain and Pain by : Richard Ambron

Download or read book The Brain and Pain written by Richard Ambron and published by Columbia University Press. This book was released on 2022-03-01 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pain is an inevitable part of existence, but severe debilitating or chronic pain is a pathological condition that diminishes the quality of life. The Brain and Pain explores the present and future of pain management, providing a comprehensive understanding based on the latest discoveries from many branches of neuroscience. Richard Ambron—the former director of a neuroscience lab that conducted leading research in this field—explains the science of how and why we feel pain. He describes how the nervous system and brain process information that leads to the experience of pain, detailing the cellular and molecular functions that are responsible for the initial perceptions of an injury. He discusses how pharmacological agents such as opiates affect the duration and intensity of pain. Ambron examines new evidence showing that discrete circuits in the brain modulate the experience of pain in response to a placebo, fear, anxiety, belief, or other circumstances, as well as how pain can be relieved by activating these circuits using mindfulness training and other nonpharmacological treatments. The book also evaluates the prospects of procedures such as deep brain stimulation and optogenetics. Current and thorough, The Brain and Pain will be invaluable for a range of people seeking to understand their options for treatment as well as students in neuroscience and medicine.

Molecular Basis of Pain Induction

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Author :
Publisher : Wiley-Liss
ISBN 13 :
Total Pages : 328 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Molecular Basis of Pain Induction by : John N. Wood

Download or read book Molecular Basis of Pain Induction written by John N. Wood and published by Wiley-Liss. This book was released on 2000-02-11 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: The scientific understanding of pain mechanisms has increased dramatically in the last few years, and, in turn, so has the need for a comprehensive volume on the molecular biology of pain and the development of analgesic drugs. Molecular Basis of Pain Induction provides a much-needed reference that covers a broad spectrum of issues while focusing on the molecular aspects of pain and the most recent genetic studies. This volume reviews the numerous recent advances in the molecular aspects of pain that have aided in the development of analgesic drugs. In such a rapidly growing area of biology, it is essential to thoroughly comprehend how genes involved in pain are identified and whether any new drugs have resulted from pain studies. The development and function of nociceptors is one of the outcomes of these vital molecular genetic studies, and this text reviews the activation of nociceptors by a variety of chemical, thermal, and mechanical stimuli. Some of the other fascinating topics discussed in Molecular Basis of Pain Induction are: * Properties and advances in the study of pain-sensing sensory neurons (nociceptors) * The use of mouse null mutants for the study of problems in genetic background and behavioral research * Insights gained from genetic studies in worms and flies that have aided in the understanding of human sensory neuron function * The detection of noxious mechanical damage * Bradykinin, which evokes pain, and opioid peptides, which block pain Containing an abundance of useful illustrations and photos to accompany this indispensable text, Molecular Basis of Pain Induction is a resourceful guide for cell and molecular biologists, researchers in pharmaceutical companies, and neuroscientists alike.

Novel Molecular Targets for the Treatment of Pain

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889664422
Total Pages : 164 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Novel Molecular Targets for the Treatment of Pain by : Tally Largent-Milnes

Download or read book Novel Molecular Targets for the Treatment of Pain written by Tally Largent-Milnes and published by Frontiers Media SA. This book was released on 2021-02-02 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topic Editor John Streicher is a co-founder and equity partner of Teleport Pharmaceuticals, LLC. All other Topic Editors declare no competing interests with regards to the Research Topic subject.

Pathological Pain

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Publisher : John Wiley & Sons
ISBN 13 : 0470869119
Total Pages : 282 pages
Book Rating : 4.4/5 (78 download)

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Book Synopsis Pathological Pain by : Derek J. Chadwick

Download or read book Pathological Pain written by Derek J. Chadwick and published by John Wiley & Sons. This book was released on 2005-01-28 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together contributions from key investigators in the area of pathological pain. It covers the molecular basis of receptors and channels involved in nociception, the possible messages that cause neuropathic plasticity, spinal plasticity in neuropathy, plastic changes in opioid systems in neuropathy and opioid tolerance, and plastic changes related to pathological pain.

Molecular Pain

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Author :
Publisher :
ISBN 13 : 9781282005228
Total Pages : pages
Book Rating : 4.0/5 (52 download)

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Book Synopsis Molecular Pain by : Min Zhuo

Download or read book Molecular Pain written by Min Zhuo and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Pain is a major health concern and a growing field of research. Molecular biologists have made rapid progress in finding relationships between genetics and pain, and ""Molecular Pain"" is the first book specifically written to bring this research to doctors and pain scientists. Unlike traditional textbooks, this book utilizes basic neuroscience to explain the mechanisms of pain. It explores current pain medicine as well as alternative treatments for chronic pain, such as acupuncture. Edited by a leading neuroscientist and written by international experts, ""Molecular Pain"" is a concise and co.

Sickle Cell Pain

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1496331834
Total Pages : 1004 pages
Book Rating : 4.4/5 (963 download)

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Book Synopsis Sickle Cell Pain by : Samir K. Ballas

Download or read book Sickle Cell Pain written by Samir K. Ballas and published by Lippincott Williams & Wilkins. This book was released on 2015-06-01 with total page 1004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sickle Cell Pain is a panoramic, in-depth exploration of every scientific, human, and social dimension of this cruel disease. This comprehensive, definitive work is unique in that it is the only book devoted to sickle cell pain, as opposed to general aspects of the disease. The 752-page book links sickle cell pain to basic, clinical, and translational research, addressing various aspects of sickle pain from molecular biology to the psychosocial aspects of the disease. Supplemented with patient narratives, case studies, and visual art, Sickle Cell Pain’s scientific rigor extends through its discussion of analgesic pharmacology, including abuse-deterrent formulations. The book also addresses in great detail inequities in access to care, stereotyping and stigmatization of patients, the implications of rapidly evolving models of care, and recent legislation and litigation and their consequences.

Acute Pain

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Publisher : Oxford University Press
ISBN 13 : 0199234728
Total Pages : 205 pages
Book Rating : 4.1/5 (992 download)

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Book Synopsis Acute Pain by : Lesley Bromley

Download or read book Acute Pain written by Lesley Bromley and published by Oxford University Press. This book was released on 2010-06-03 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text covers the fundamentals of pain, the pharmacology of drugs used, and summarises the current evidence base for the management of acute pain. It provides practical direct clinical applications and strategies for the management of specific medical conditions in patient groups such as the elderly

Immune and Glial Regulation of Pain

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Publisher :
ISBN 13 :
Total Pages : 464 pages
Book Rating : 4.8/5 (121 download)

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Book Synopsis Immune and Glial Regulation of Pain by : Joyce A. De Leo

Download or read book Immune and Glial Regulation of Pain written by Joyce A. De Leo and published by . This book was released on 2007 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Review of immune and glial factors within the peripheral and central nervous systems that relate to chronic pain states. Discussion of novel immune and glial targets for clinical pain control that may yield new analgesic drugs"--Provided by publisher.

TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades

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Publisher : CRC Press
ISBN 13 : 1420005847
Total Pages : 502 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades by : Wolfgang B. Liedtke, MD, PH.D.

Download or read book TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades written by Wolfgang B. Liedtke, MD, PH.D. and published by CRC Press. This book was released on 2006-09-29 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st

Hypnosis for Chronic Pain Management : Workbook

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Publisher : Oxford University Press, USA
ISBN 13 : 0199857571
Total Pages : 161 pages
Book Rating : 4.1/5 (998 download)

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Book Synopsis Hypnosis for Chronic Pain Management : Workbook by : Harborview Medical Center Mark P. Jensen Professor and Vice Chair for Research Department of Rehabilitation Medicine

Download or read book Hypnosis for Chronic Pain Management : Workbook written by Harborview Medical Center Mark P. Jensen Professor and Vice Chair for Research Department of Rehabilitation Medicine and published by Oxford University Press, USA. This book was released on 2011-04-02 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: If you suffer from chronic pain, whether as a result of an injury, illness, or accident, you know it can interfere with every aspect of your life. You may also know the medical treatments currently available are limited and, for many, ineffective. Current research has shown hypnosis to be an effective treatment for managing chronic pain, and almost all patients who learn self-hypnosis skills benefit from this approach. The hypnosis treatment found in this workbook has been scientifically tested and proven effective for reducing the intensity of chronic pain, including migraines, back pain, and tension headaches, among others. This workbook explains how to use these techniques to manage your chronic pain and take back control of your life and your health. Used in combination with the program described in the corresponding therapist guide, this workbook teaches you self-hypnosis skills for lessening your pain, enhancing your sleep, and improving your mood. The first chapters will help you understand how hypnosis works by changing how your brain deals with information it receives from the body. The complete hypnosis treatment described in this book, alongside the treatment you receive from your clinician, will ultimately teach you skills for pain management that you can use at any time, and for the rest of your life. "An excellent blueprint to understanding pain and the fundamentals of how hypnosis combined with CBT can offer pain amelioration. Perfect, even for uninitiated practitioners who wish to use empirically based scripts."--Jeffrey Zeig, Ph.D., The Milton Erickson Foundation "Pain can too easily enslave people, holding them captive in many different ways. It is a liberating theme of empowerment that echoes throughout Dr. Jensen's work: he empowers clinicians to work more knowledgeably and skillfully with people who suffer painful conditions using his therapist guide, and he encourages the suffering individual to break free from pain's grip with the practical pain management skills taught in his workbook. Dr. Jensen's vision for the many ways hypnosis can help reduce the debilitating effects of painful conditions is fresh, inspiring and should be regularly integrated into every pain management program."--Michael D. Yapko, Ph.D., Clinical Psychologist and author of Trancework: An Introduction to the Practice of Clinical Hypnosis (Third Edition) and Treating Depression with Hypnosis

Acute Pain Management

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Publisher : Cambridge University Press
ISBN 13 : 0521874912
Total Pages : 729 pages
Book Rating : 4.5/5 (218 download)

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Book Synopsis Acute Pain Management by : Raymond S. Sinatra

Download or read book Acute Pain Management written by Raymond S. Sinatra and published by Cambridge University Press. This book was released on 2009-04-27 with total page 729 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides an overview of pain management useful to specialists as well as non-specialists, surgeons, and nursing staff.

Mechanisms of Vascular Disease

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Publisher : University of Adelaide Press
ISBN 13 : 1922064009
Total Pages : 589 pages
Book Rating : 4.9/5 (22 download)

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Book Synopsis Mechanisms of Vascular Disease by : Robert Fitridge

Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

The Oxford Handbook of the Neurobiology of Pain

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Publisher : Oxford University Press, USA
ISBN 13 : 0190860502
Total Pages : 939 pages
Book Rating : 4.1/5 (98 download)

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Book Synopsis The Oxford Handbook of the Neurobiology of Pain by : John N. Wood

Download or read book The Oxford Handbook of the Neurobiology of Pain written by John N. Wood and published by Oxford University Press, USA. This book was released on 2020 with total page 939 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook is currently in development, with individual articles publishing online in advance of print publication. At this time, we cannot add information about unpublished articles in this handbook, however the table of contents will continue to grow as additional articles pass through the review process and are added to the site. Please note that the online publication date for this handbook is the date that the first article in the title was published online.

Sodium Channels, Pain, and Analgesia

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Publisher : Springer Science & Business Media
ISBN 13 : 376437411X
Total Pages : 204 pages
Book Rating : 4.7/5 (643 download)

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Book Synopsis Sodium Channels, Pain, and Analgesia by : Kevin Coward

Download or read book Sodium Channels, Pain, and Analgesia written by Kevin Coward and published by Springer Science & Business Media. This book was released on 2006-01-17 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sodium channels confer excitability on neurons in nociceptive pathways and exhibit neuronal tissue specific and injury regulated expression. This volume provides recent insights into the control of expression, functioning and membrane trafficking of nervous system sodium channels and reviews why sodium channel sub-types are potentially important drug targets in the treatment of pain. The roles of sodium channels in dental and visceral pain are also addressed. The emerging role of sodium channel Nav1.3 in neuropathic states is another important theme. Authors from the pharmaceutical industry discuss pharmacological approaches to the drug targeting of sodium channels, and in particular Nav1.8, exclusively expressed in nociceptive neurons. The final chapter highlights the functional diversity of sodium channels in part provided by post-transcriptional processing and the insights into sodium channel function that are being provided by tissue specific and inducible gene knock-out technology.

The Neuron

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Publisher : Oxford University Press, USA
ISBN 13 : 9780195145236
Total Pages : 640 pages
Book Rating : 4.1/5 (452 download)

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Book Synopsis The Neuron by : Irwin B. Levitan

Download or read book The Neuron written by Irwin B. Levitan and published by Oxford University Press, USA. This book was released on 2002 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intended for use by advanced undergraduate, graduate and medical students, this book presents a study of the unique biochemical and physiological properties of neurons, emphasising the molecular mechanisms that generate and regulate their activity.