Modulation of Nocturnin Phosphatase Activity Through the Disordered Amino Terminus

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (139 download)

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Book Synopsis Modulation of Nocturnin Phosphatase Activity Through the Disordered Amino Terminus by : Anushka Christobel Wickramaratne

Download or read book Modulation of Nocturnin Phosphatase Activity Through the Disordered Amino Terminus written by Anushka Christobel Wickramaratne and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Lipid Transfer in Lipoprotein Metabolism and Cardiovascular Disease

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Publisher : Springer Nature
ISBN 13 : 981156082X
Total Pages : 235 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Lipid Transfer in Lipoprotein Metabolism and Cardiovascular Disease by : Xian-Cheng Jiang

Download or read book Lipid Transfer in Lipoprotein Metabolism and Cardiovascular Disease written by Xian-Cheng Jiang and published by Springer Nature. This book was released on 2020-07-23 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an up-to-date review of the fundamentals of lipid metabolism and its role in cardiovascular diseases. Focusing on lipid transfer proteins in the circulation and cells, the role of important lipid transporters, the effect of recently discovered lipid binding proteins, and the link between lipid metabolism disorders and cardiovascular diseases, it covers phospholipid transfer protein, cholesteryl ester transfer protein, lipopolysaccharide binding protein, microsomal triglyceride transfer protein, ABC binding cassette members, and more. The book offers graduate students and researchers a coherent overview of lipid transfer and transport, as well as the limitations of current research in the field, and promotes further studies on cardiovascular diseases, as well as pharmaceutical research on drug discovery based on lipid transfer, transport, and binding.

The Circadian Clock

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Publisher : Springer Science & Business Media
ISBN 13 : 1441912622
Total Pages : 306 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis The Circadian Clock by : Urs Albrecht

Download or read book The Circadian Clock written by Urs Albrecht and published by Springer Science & Business Media. This book was released on 2010-01-23 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the invitation to edit this volume, I wanted to take the opportunity to assemble reviews on different aspects of circadian clocks and rhythms. Although most c- tributions in this volume focus on mammalian circadian clocks, the historical int- duction and comparative clocks section illustrate the importance of various other organisms in deciphering the mechanisms and principles of circadian biology. Circadian rhythms have been studied for centuries, but only recently, a mole- lar understanding of this process has emerged. This has taken research on circadian clocks from mystic phenomenology to a mechanistic level; chains of molecular events can describe phenomena with remarkable accuracy. Nevertheless, current models of the functioning of circadian clocks are still rudimentary. This is not due to the faultiness of discovered mechanisms, but due to the lack of undiscovered processes involved in contributing to circadian rhythmicity. We know for example, that the general circadian mechanism is not regulated equally in all tissues of m- mals. Hence, a lot still needs to be discovered to get a full understanding of cir- dian rhythms at the systems level. In this respect, technology has advanced at high speed in the last years and provided us with data illustrating the sheer complexity of regulation of physiological processes in organisms. To handle this information, computer aided integration of the results is of utmost importance in order to d- cover novel concepts that ultimately need to be tested experimentally.

Circadian Clocks: Role in Health and Disease

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Publisher : Springer
ISBN 13 : 1493934503
Total Pages : 382 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Circadian Clocks: Role in Health and Disease by : Michelle L. Gumz

Download or read book Circadian Clocks: Role in Health and Disease written by Michelle L. Gumz and published by Springer. This book was released on 2016-02-29 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book sheds new light on the molecular mechanisms that generate circadian rhythms. It examines how biological rhythms influence physiological processes such as sleep, hormone synthesis and secretion, immunity, kidney function, the cardiovascular system, blood pressure, and the digestive system. Clinical implications are considered while exploring the impact of rhythms on neuropsychiatric disorders and chronotherapy’s potential for reducing cardiovascular risk. Offering a cross-section of expertise in both basic and translational (bench-to-bedside) research, this book serves as a guide for physicians and scientists who wish to learn more about the impact of circadian rhythms on physiological processes in health and disease.

Circadian Rhythms and Their Impact on Aging

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Publisher : Springer
ISBN 13 : 3319645439
Total Pages : 367 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Circadian Rhythms and Their Impact on Aging by : S. Michal Jazwinski

Download or read book Circadian Rhythms and Their Impact on Aging written by S. Michal Jazwinski and published by Springer. This book was released on 2017-10-24 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological rhythms time the ebb and flow of virtually every physiological process, and their mutual coordination guarantees the integrity of the organism over space and time. Aging leads to the disintegration of this coordination, as well as to changes in the amplitude and/or frequency of the underlying rhythms. The results of this are accelerated loss of health during aging, and in experimental model systems curtailed lifespan occurs. This book will examine the machinery that constitutes circadian systems and how they impact physiologic processes. It will also discuss how disturbances of circadian rhythms can lead to complex diseases associated with aging. Much of this treatment will focus on metabolism and genome stability. Importantly, the chapters in this book will encompass work in several different models, in addition to human. The book will conclude with a discussion of modeling approaches to biologic cycles and chronotherapy, for future research and translation.

Circadian Medicine

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Publisher : John Wiley & Sons
ISBN 13 : 1118467787
Total Pages : 405 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis Circadian Medicine by : Christopher S. Colwell

Download or read book Circadian Medicine written by Christopher S. Colwell and published by John Wiley & Sons. This book was released on 2015-07-07 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Circadian rhythms, the biological oscillations based around our 24-hour clock, have a profound effect on human physiology and healthy cellular function. Circadian Rhythms: Health and Disease is a wide-ranging foundational text that provides students and researchers with valuable information on the molecular and genetic underpinnings of circadian rhythms and looks at the impacts of disruption in our biological clocks in health and disease. Circadian Rhythms opens with chapters that lay the fundamental groundwork on circadian rhythm biology. Section II looks at the impact of circadian rhythms on major organ systems. Section III then turns its focus to the central nervous system. The book then closes with a look at the role of biological rhythms in aging and neurodegeneration. Written in an accessible and informative style, Circadian Rhythms: Health and Disease,will be an invaluable resource and entry point into this fascinating interdisciplinary field that brings together aspects of neuroscience, cell and molecular biology, and physiology.

Chronobiology and Obesity

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Publisher : Springer Science & Business Media
ISBN 13 : 1461450829
Total Pages : 199 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Chronobiology and Obesity by : Marta Garaulet

Download or read book Chronobiology and Obesity written by Marta Garaulet and published by Springer Science & Business Media. This book was released on 2012-11-13 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: Circadian rhythms are such an innate part of our lives that we rarely pause to speculate why they even exist. Some studies have suggested that the disruption of the circadian system may be causal for obesity and manifestations of Metabolic Syndrome (MetS). Shift-work, sleep-deprivation and bright-light-exposure at night are related to increased adiposity (obesity) and prevalence of MetS. It has been provided evidence of clock genes expression in human adipose tissue and demonstrated its association with different components of the MetS. Moreover, current studies are illustrating the particular role of different clock genes variants and their predicted haplotypes in MetS. The purpose of “Chronobiology and Obesity” is to describe the mechanisms implicated in the interaction between chonodisruption and metabolic-related illnesses, such as obesity and MetS, with different approaches.

Redox Biochemistry

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Publisher : John Wiley & Sons
ISBN 13 : 9780470177327
Total Pages : 350 pages
Book Rating : 4.1/5 (773 download)

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Book Synopsis Redox Biochemistry by : Ruma Banerjee

Download or read book Redox Biochemistry written by Ruma Banerjee and published by John Wiley & Sons. This book was released on 2007-12-04 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the premier, single-source reference on redox biochemistry, a rapidly emerging field. This reference presents the basic principles and includes detailed chapters focusing on various aspects of five primary areas of redox biochemistry: antioxidant molecules and redox cofactors; antioxidant enzymes; redox regulation of physiological processes; pathological processes related to redox; and specialized methods. This is a go-to resource for professionals in pharmaceuticals, medicine, immunology, nutrition, and environmental fields and an excellent text for upper-level students.

Glial ⇔ Neuronal Signaling

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Publisher : Springer Science & Business Media
ISBN 13 : 9781402079368
Total Pages : 460 pages
Book Rating : 4.0/5 (793 download)

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Book Synopsis Glial ⇔ Neuronal Signaling by : Glenn I. Hatton

Download or read book Glial ⇔ Neuronal Signaling written by Glenn I. Hatton and published by Springer Science & Business Media. This book was released on 2004-05-31 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glial Neuronal Signaling fills a need for a monograph/textbook to be used in advanced courses or graduate seminars aimed at exploring glial-neuronal interactions. Even experts in the field will find useful the authoritative summaries of evidence on ion channels and transporters in glia, genes involved in signaling during development, metabolic cross talk and cooperation between astrocytes and neurons, to mention but a few of the timely summaries of a wide range of glial-neuronal interactions. The chapters are written by the top researchers in the field of glial-neuronal signaling, and cover the most current advances in this field. The book will also be of value to the workers in the field of cell biology in general. When we think about the brain we usually think about neurons. Although there are 100 billion neurons in mammalian brain, these cells do not constitute a majority. Quite the contrary, glial cells and other non-neuronal cells are 10-50 times more numerous than neurons. This book is meant to integrate the emerging body of information that has been accumulating, revealing the interactive nature of the brain's two major neural cell types, neurons and glia, in brain function.

Intestinal Lipid Metabolism

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Publisher : Springer Science & Business Media
ISBN 13 : 9780306462412
Total Pages : 464 pages
Book Rating : 4.4/5 (624 download)

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Book Synopsis Intestinal Lipid Metabolism by : Charles M. Mansbach

Download or read book Intestinal Lipid Metabolism written by Charles M. Mansbach and published by Springer Science & Business Media. This book was released on 2000-11-30 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book was stimulated by the enthusiasm shown by attendees at the meetings in Saxon River, VT, sponsored by the Federation ofAmerican Societies for Experimental Biology (FASEB), on the subject of the intestinal processing of lipids. When these meetings were first started in 1990, the original organizers, two of whom are editors ofthis volume (CMM and PT), had two major goals. The first was to bring together a diverse group ofinvestiga tors who had the common goal of gaining a better understanding of how the intestine ab sorbs lipids. The second was to stimulate the interest of younger individuals whom we wished to recruit into what we believed was an exciting and fruitful area ofresearch. Since that time, the field has opened up considerably with new questions being asked and new an swers obtained, suggesting that our original goals for the meetings were being met. In the same spirit, it occurred to us that there has not been a recentbook that draws to gethermuch ofthe informationavailableconcerninghow the intestineprocesses lipids. This book is intended to reach investigators with an interest in this area and their pre- and post doctoral students. The chapters are written by individuals who have a long-term interest in the areas about which they write, and many have been speakers at the subsequent FASEB conferences that have followed on the first.

The Rhythms Of Life

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Publisher : Profile Books
ISBN 13 : 1847653723
Total Pages : 288 pages
Book Rating : 4.8/5 (476 download)

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Book Synopsis The Rhythms Of Life by : Leon Kreitzman

Download or read book The Rhythms Of Life written by Leon Kreitzman and published by Profile Books. This book was released on 2011-09-30 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Popular science at its most exciting: the breaking new world of chronobiology - understanding the rhythm of life in humans and all plants and animals. The entire natural world is full of rhythms. The early bird catches the worm -and migrates to an internal calendar. Dormice hibernate away the winter. Plants open and close their flowers at the same hour each day. Bees search out nectar-rich flowers day after day. There are cicadas that can breed for only two weeks every 17 years. And in humans: why are people who work anti-social shifts more illness prone and die younger? What is jet-lag and can anything help? Why do teenagers refuse to get up in the morning, and are the rest of us really 'larks' or 'owls'? Why are most people born (and die) between 3am-5am? And should patients be given medicines (and operations) at set times of day, because the body reacts so differently in the morning, evening and at night? The answers lie in our biological clocks the mechanisms which give order to all living things. They impose a structure that enables us to change our behaviour in relation to the time of day, month or year. They are reset at sunrise and sunset each day to link astronomical time with an organism's internal time.

Dualities and Representations of Lie Superalgebras

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Publisher : American Mathematical Soc.
ISBN 13 : 0821891189
Total Pages : 323 pages
Book Rating : 4.8/5 (218 download)

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Book Synopsis Dualities and Representations of Lie Superalgebras by : Shun-Jen Cheng

Download or read book Dualities and Representations of Lie Superalgebras written by Shun-Jen Cheng and published by American Mathematical Soc.. This book was released on 2012 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives a systematic account of the structure and representation theory of finite-dimensional complex Lie superalgebras of classical type and serves as a good introduction to representation theory of Lie superalgebras. Several folklore results are rigorously proved (and occasionally corrected in detail), sometimes with new proofs. Three important dualities are presented in the book, with the unifying theme of determining irreducible characters of Lie superalgebras. In order of increasing sophistication, they are Schur duality, Howe duality, and super duality. The combinatorics of symmetric functions is developed as needed in connections to Harish-Chandra homomorphism as well as irreducible characters for Lie superalgebras. Schur-Sergeev duality for the queer Lie superalgebra is presented from scratch with complete detail. Howe duality for Lie superalgebras is presented in book form for the first time. Super duality is a new approach developed in the past few years toward understanding the Bernstein-Gelfand-Gelfand category of modules for classical Lie superalgebras. Super duality relates the representation theory of classical Lie superalgebras directly to the representation theory of classical Lie algebras and thus gives a solution to the irreducible character problem of Lie superalgebras via the Kazhdan-Lusztig polynomials of classical Lie algebras.

Mechanisms of Transcription

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Publisher : CSHL Press
ISBN 13 : 9780879695507
Total Pages : 724 pages
Book Rating : 4.6/5 (955 download)

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Book Synopsis Mechanisms of Transcription by : Bruce Stillman

Download or read book Mechanisms of Transcription written by Bruce Stillman and published by CSHL Press. This book was released on 1998 with total page 724 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of a summer 1998 meeting, presenting results of recent studies in gene transcription. Covers events ranging from activation, through promoter recognition, repression, chromosome structure, chromatin remodeling, initiation and elongation, and regulatory complexes and pathways. Subjects include targeting sir proteins to sites of action, the yeast RNA polymerase III transcription machinery, nuclear matrix attachment regions to confer long-range function on immunoglobulin, ATP-dependent remodeling of chromatin, and the transcriptional basis of steroid physiology. Annotation copyrighted by Book News, Inc., Portland, OR.

Life Extension

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Publisher : Springer
ISBN 13 : 3319183265
Total Pages : 351 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Life Extension by : Alexander M. Vaiserman

Download or read book Life Extension written by Alexander M. Vaiserman and published by Springer. This book was released on 2015-06-09 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: ​This book looks at aging through research on Drosophila, the fruit fly that is one of the most widely used model organisms in bio gerontology. Work in model organisms can expand the theoretical knowledge of aging: it yields valuable insight into the molecular and cellular processes that underlie aging process, and it can perhaps provide new therapeutic targets for the treatment of age-related disorders in humans. Drosophila models have been developed for a large variety of aging-related processes and diseases, and this book provides readers with an overview of current research on the use of the Drosophila model to understand the genetic, molecular and physiological mechanisms that underlie the aging process. Themes of health span, life extension and longevity-associated genes emerge in this collation of international research on Drosophila that is of relevance to geriatrics and gerontology, animal genetics and genomics, and biomedicine. This fascinating, illustrated book will be of interest to a wide audience, ranging from academic researchers to the general reader.

Animal Physiology

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Publisher :
ISBN 13 : 9781605357379
Total Pages : 828 pages
Book Rating : 4.3/5 (573 download)

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Book Synopsis Animal Physiology by : Richard W. (Michigan State University) Hill

Download or read book Animal Physiology written by Richard W. (Michigan State University) Hill and published by . This book was released on 2017-10-05 with total page 828 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published by Sinauer Associates, an imprint of Oxford University Press.

The Physiological Clock

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Publisher :
ISBN 13 :
Total Pages : 284 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis The Physiological Clock by : Erwin Bünning

Download or read book The Physiological Clock written by Erwin Bünning and published by . This book was released on 1973 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Inorganic Polyphosphates

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Publisher : Springer Science & Business Media
ISBN 13 : 3642584446
Total Pages : 325 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Inorganic Polyphosphates by : Heinz C. Schröder

Download or read book Inorganic Polyphosphates written by Heinz C. Schröder and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inorganic polyphosphates - polymers of orthophosphate linked by high-energy phosphoanhydride bonds - have been found in apparently all forms of life, from bacteria, yeasts and fungi to higher plants and animals. These polymers, which had been neglected for a long time, have become a fascinating area of research in the last few years. This volume summarizes the present state of knowledge about the metabolism and function of inorganic polyphosphates. In addition, the methods to study these polymers as well as the biotechnological applications of inorganic polyphosphates are described. The 15 chapters of this volume, dealing with different aspects of polyphosphate research, are written by experts in the field. This book represents a valuable source of information not only for researchers working on this subject, but also for scientists interested in fundamental aspects of cell and energy metabolism.