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Modulation Of Inflammatory Responses By Green And Black Tea In Lps Induced Raw 2647 Cells
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Book Synopsis Modulation of Inflammatory Responses by Green and Black Tea in LPS-induced RAW 264.7 Cells by : Caroline Rueda Summers
Download or read book Modulation of Inflammatory Responses by Green and Black Tea in LPS-induced RAW 264.7 Cells written by Caroline Rueda Summers and published by . This book was released on 2009 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Keywords: LPS, tea, mouse macrophage, inflammation.
Book Synopsis Modulation of Inflammatory Responses by Green and Black Tea in LPS-induced RAW 264.7 Cells by :
Download or read book Modulation of Inflammatory Responses by Green and Black Tea in LPS-induced RAW 264.7 Cells written by and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently, the World Health Organization estimated that chronic diseases are responsible for 46% of disease occurrence and 59% of all deaths worldwide. Growing evidence suggests that increasing chronic disease incidence is dependent upon several factors, including inadequate consumption of antioxidant-rich fruits and vegetables and chronic inflammation. Many researchers have previously investigated potential health benefits associated with consuming plant-based foods, and the ability of these foods to prevent or suppress the pathologies linked to chronic diseases. Specifically, plant-based bioactive compounds called polyphenols have been widely studied, and show promise as a therapeutic agent against chronic diseases. Tea is produced from the leaves of the Camellia sinensis plant and, aside from water, is the most popular beverage in the world. Green tea, black tea, and oolong tea are the three major types of commercially produced tea. Black tea comprises over 75% of global tea production and consumption, followed by green tea at approximately 20%, and oolong tea at less than 2%. For centuries, tea has been known for its health effects. It has historically been used as a medicine in China and Japan. Tea polyphenols are particularly thought to have chemopreventive and cardioprotective effects due to their antioxidant and anti-inflammatory properties. Previous in vitro and animal studies have analyzed the anti-inflammatory activity of polyphenols, and the specific mechanisms by which these compounds suppress inflammation. But, to our knowledge, few studies have investigated teaâ€"! anti-inflammatory capacity as a whole food, or compared the potential anti-inflammatory effects of different tea types. Therefore, the objectives of the following study were to evaluate total phenol content in green tea (GT) and black tea (BT); to assess viability of cells exposed to GT, BT, and LPS; and to measure the modulation of inflammatory responses in lipopolysaccharide (LPS)-induced.
Book Synopsis Mammalian Transient Receptor Potential (TRP) Cation Channels by : Bernd Nilius
Download or read book Mammalian Transient Receptor Potential (TRP) Cation Channels written by Bernd Nilius and published by Springer. This book was released on 2014-06-24 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression. Thereby this volume on Transient Receptor Potential (TRP) Channels provides valuable information for readers with different expectations and backgrounds, for those who are approaching this field of research as well as for those wanting to make a trip to TRPs.
Book Synopsis Fascinating Facts About Phytonutrients in Spices and Healthy Food by : Louis S. Premkumar
Download or read book Fascinating Facts About Phytonutrients in Spices and Healthy Food written by Louis S. Premkumar and published by Xlibris Corporation. This book was released on 2014-03-25 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: For centuries, there have been claims that healthy food garnished with exotic spices and condiments provides vital nutrients that help ward off diseases, especially preventable diseases such as diabetes and heart disease (hypertension, coronary artery disease) and promote longevity. The purpose of writing this book is to update the public about the health benefits of ingredients (phytochemicals) in spices and healthy food using existing scientific evidence. The ultimate proof of health benefits will be deciphered by the isolation and identification of specific phytochemicals acting on specific receptors in the body exerting their biological effects. The important point being emphasized is that if the physiological effect of an ingredient is glaring, it is considered to elicit a significant response. However, when the effect of an ingredient is significant, yet the effect is not readily perceivable then the usefulness goes unnoticed and can be questioned as a myth. For example, coffee has several ingredients, but only caffeine acting on the adenosine receptors stimulates the central nervous system and promotes wakefulness. Similarly, the specific active ingredient in hot chili pepper, capsaicin, activates a member of a recently identified family of receptors called transient receptor potential (TRP) channels. TRP vanilloid 1 (TRPV1), which is involved in certain modalities of pain, promotes the release of hormones in the gastrointestinal (GI) tract. Although, the bioavailability of the active ingredients is low, it is important to realize that these ingredients can cause significant local effects in the GI tract by preventing cholesterol regeneration by subduing microbiota, inhibiting precancerous growth by promoting calcium influx and stimulating nerve endings to transmit information and to release of gut hormones that are involved in regulating a variety of functions including appetite and satiety.
Book Synopsis Recent Advances in Glucocorticoid Receptor Action by : A. Cato
Download or read book Recent Advances in Glucocorticoid Receptor Action written by A. Cato and published by Springer. This book was released on 2014-03-12 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Microbial Inoculants in Sustainable Agricultural Productivity by : Dhananjaya Pratap Singh
Download or read book Microbial Inoculants in Sustainable Agricultural Productivity written by Dhananjaya Pratap Singh and published by Springer. This book was released on 2016-02-22 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: How to achieve sustainable agricultural production without compromising environmental quality, agro-ecosystem function and biodiversity is a serious consideration in current agricultural practices. Farming systems’ growing dependency on chemical inputs (fertilizers, pesticides, nutrients etc.) poses serious threats with regard to crop productivity, soil fertility, the nutritional value of farm produce, management of pests and diseases, agro-ecosystem well-being, and health issues for humans and animals. At the same time, microbial inoculants in the form of biofertilizers, plant growth promoters, biopesticides, soil health managers, etc. have gained considerable attention among researchers, agriculturists, farmers and policy makers. The first volume of the book Microbial Inoculants in Sustainable Agricultural Productivity - Research Perspectives highlights the efforts of global experts with regard to various aspects of microbial inoculants. Emphasis is placed on recent advances in microbiological techniques for the isolation, characterization, identification and evaluation of functional properties using biochemical and molecular tools. The taxonomic characterization of agriculturally important microorganisms is documented, along with their applications in field conditions. The book exploresthe identification, characterization and diversity analysis of endophytic microorganisms in various crops including legumes/ non-legumes, as well as the assessment of their beneficial impacts in the context of promotingplant growth. Moreover, it provides essential updates onthe diversity and role of plant growth promoting rhizobacteria (PGPR) and arbuscular mycorrhizal mycorrhizal fungi (AMF). Further chaptersexamine in detailbiopesticides, thehigh-density cultivation of bioinoculants in submerged culture, seed biopriming strategies for abiotic and biotic stress tolerance, andPGPR as abio-control agent. Given its content,the book offers a valuable resource for researchers involved in research and development concerningPGPR, biopesticides and microbial inoculants.
Book Synopsis Bioactive Molecules in Food by : Jean-Michel Mérillon
Download or read book Bioactive Molecules in Food written by Jean-Michel Mérillon and published by Springer Nature. This book was released on 2019-01-25 with total page 2353 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference work provides comprehensive information about the bioactive molecules presented in our daily food and their effect on the physical and mental state of our body. Although the concept of functional food is new, the consumption of selected food to attain a specific effect existed already in ancient civilizations, namely of China and India. Consumers are now more attentive to food quality, safety and health benefits, and the food industry is led to develop processed- and packaged-food, particularly in terms of calories, quality, nutritional value and bioactive molecules. This book covers the entire range of bioactive molecules presented in daily food, such as carbohydrates, proteins, lipids, isoflavonoids, carotenoids, vitamin C, polyphenols, bioactive molecules presented in wine, beer and cider. Concepts like French paradox, Mediterranean diet, healthy diet of eating fruits and vegetables, vegan and vegetarian diet, functional foods are described with suitable case studies. Readers will also discover a very timely compilation of methods for bioactive molecules analysis. Written by highly renowned scientists of the field, this reference work appeals to a wide readership, from graduate students, scholars, researchers in the field of botany, agriculture, pharmacy, biotechnology and food industry to those involved in manufacturing, processing and marketing of value-added food products.
Book Synopsis Pharmacology and Applications of Naturally Occurring Iridoids by : Biswanath Dinda
Download or read book Pharmacology and Applications of Naturally Occurring Iridoids written by Biswanath Dinda and published by Springer. This book was released on 2019-03-26 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, the author provides expert analysis on naturally occurring iridoids, their chemistry and their distribution in plants and insects. Particular attention is given to the pharmacology of iridoids and their prospective applications in pharmaceutical and agricultural industries. Iridoids are found in a wide variety of plants and some insects, and they are structurally derived from monoterpenoid natural products. In the first two chapters of this book, the author describes the iridoids classification, occurrence and distribution in plants and insects. The following chapters cover different chromatographic and spectroscopic techniques that can be used to identify and quantify iridoids in herbal formulations, and also the biosynthesis of iridoids, in which the reader will discover a metabolomics and transcriptomics analysis to identify the genes involved in the biosynthesis. The final chapters provide insights on several pharmacological activities of iridoids, their physiological role in insects, pharmacokinetics in mammals, insects and microorganisms, and their applications in medicine and agriculture. This book will engage students and researchers interested in the chemistry of natural products, and it will also appeal to medicinal chemists and practitioners working in the design of new herbal drugs with bioactive pure iridoids.
Book Synopsis Plant and Human Health, Volume 1 by : Munir Ozturk
Download or read book Plant and Human Health, Volume 1 written by Munir Ozturk and published by Springer. This book was released on 2018-10-02 with total page 805 pages. Available in PDF, EPUB and Kindle. Book excerpt: Early anthropological evidence for plant use as medicine is 60,000 years old as reported from the Neanderthal grave in Iraq. The importance of plants as medicine is further supported by archeological evidence from Asia and the Middle East. Today, around 1.4 billion people in South Asia alone have no access to modern health care, and rely instead on traditional medicine to alleviate various symptoms. On a global basis, approximately 50 to 80 thousand plant species are used either natively or as pharmaceutical derivatives for life-threatening conditions that include diabetes, hypertension and cancers. As the demand for plant-based medicine rises, there is an unmet need to investigate the quality, safety and efficacy of these herbals by the “scientific methods”. Current research on drug discovery from medicinal plants involves a multifaceted approach combining botanical, phytochemical, analytical, and molecular techniques. For instance, high throughput robotic screens have been developed by industry; it is now possible to carry out 50,000 tests per day in the search for compounds, which act on a key enzyme or a subset of receptors. This and other bioassays thus offer hope that one may eventually identify compounds for treating a variety of diseases or conditions. However, drug development from natural products is not without its problems. Frequent challenges encountered include the procurement of raw materials, the selection and implementation of appropriate high-throughput bioassays, and the scaling-up of preparative procedures. Research scientists should therefore arm themselves with the right tools and knowledge in order to harness the vast potentials of plant-based therapeutics. The main objective of Plant and Human Health is to serve as a comprehensive guide for this endeavor. Volume 1 highlights how humans from specific areas or cultures use indigenous plants. Despite technological developments, herbal drugs still occupy a preferential place in a majority of the population in the third world and have slowly taken roots as alternative medicine in the West. The integration of modern science with traditional uses of herbal drugs is important for our understanding of this ethnobotanical relationship. Volume 2 deals with the phytochemical and molecular characterization of herbal medicine. Specifically, it focuess on the secondary metabolic compounds, which afford protection against diseases. Lastly, Volume 3 discusses the physiological mechanisms by which the active ingredients of medicinal plants serve to improve human health. Together this three-volume collection intends to bridge the gap for herbalists, traditional and modern medical practitioners, and students and researchers in botany and horticulture.
Book Synopsis Antioxidant Properties of Spices, Herbs and Other Sources by : Denys J. Charles
Download or read book Antioxidant Properties of Spices, Herbs and Other Sources written by Denys J. Charles and published by Springer Science & Business Media. This book was released on 2012-11-27 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: The scientific world and modern society today is experiencing the dawning of an era of herbal medicine. Extensive research has shown that aromatic plants are important anti-inflammatory, antioxidant, anti aging and immune boosting delectable foods, with the magic and miracle to boost our immune system providing us with extended and an improved quality of life. Apart from making bland recipes into welcoming or interesting victories, herbs and spices have stirred the minds of the research community to look deeper into its active components from a functional perspective. It is essential to present the scientific and medicinal aspect of herbs and spices together with the analysis of constituents, its medicinal application, toxicology and its physiological effects. Herbs and spices with high levels of antioxidants are in great demand as they tend to promote health and prevent diseases naturally assuring increased safety and reliability for consumers. Herbs and spices are not only known for taste and flavor, but today research has opened up a new realm in which the antioxidant properties of these aromatic plants provide preservation for foods and health benefits for consumers who look forward to concrete scientific research to guide them further and explore herbal medicine. The aim of this book is to create awareness in society about the reliability of medicinal properties of certain herbs and spices through scientific and scholarly research.
Download or read book Bee Products written by Avshalom Mizrahi and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nature .and diversity of presentations at the conference on: "Bee Products: Prop erties, Applications and Apitherapy" held at Tel-Aviv on May 26--30, 1996, emphasize the increasing interest of physicians, practitioners, scientists, herbalists, dieticians, cosmeti cians, microbiologists, and beekeepers in different facets of bee products. This volume consists of a selection of 31 contributions presented at the conference and which provide information on the present status of our knowledge in this area. In spite of their diversity, they reflect the mainstream of the conference, namely: "Imported" Prod ucts (honey, pollen and propolis), Exocrine Secretions of Workers (venom, royal jelly). Toxicity and Contaminants, Quality Control, Marketing, Apitherapy, Cosmetics, etc. Since antiquity, honey as well as other bee products were used as food, as a cure for ailments of humans and animals, and as cosmetics. We hope that this volume will contribute to interdisciplinary studies on chemical composition, pharmacological effects, nutrition, and other aspects of bee products. Critical and unbiased experimental research may unravel the yet unknown composition and mode of action of bee products and elucidate many unanswered questions. The noteworthy features of this conference were the participants from all parts of the world and of different cultural backgrounds, who shared their keen interest and curios ity regarding honey bees and their products. We thank all of them for their personal con tribution to the success of this conference.
Book Synopsis Oxidants and Antioxidants by : Lester Packer
Download or read book Oxidants and Antioxidants written by Lester Packer and published by Gulf Professional Publishing. This book was released on 1999 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: General Description of the Series: The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences. Key Features * Total Antioxidant Activity * Vitamin C * Polyphenols and Flavanoids * Thiols * Vitamin E and Coenzyme Q10 * Carotenoids and Retinoids.
Book Synopsis Evidence-Based Validation of Herbal Medicine by : Pulok K. Mukherjee
Download or read book Evidence-Based Validation of Herbal Medicine written by Pulok K. Mukherjee and published by Elsevier. This book was released on 2022-07-12 with total page 858 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evidence-Based Validation of Herbal Medicines: Translational Research on Botanicals brings together current thinking and practice in the characterization and validation of natural products. The book describes different approaches and techniques for evaluating the quality, safety and efficacy of herbal medicine, particularly methods to assess their activity and understand compounds responsible and their probable underlying mechanisms of action. This book brings together the views, expertise and experiences of scientific experts in the field of medicinal plant research, hence it will be useful for researcher who want to know more about the natural lead with their validation and also useful to exploit traditional medicines. - Includes state-of-the-art methods for detecting, isolating and performing structure elucidation by degradation and spectroscopic techniques - Highlights the trends in validation and value addition of herbal medicine with different scientific approaches used in therapeutics - Contains several all-new chapters on topics such as traditional-medicine-inspired drug development to treat emerging viral diseases, medicinal plants in antimicrobial resistance, TLC bio profiling, botanicals as medicinal foods, bioprospecting and bioassay-guided isolation of medicinal plants, immunomodulators from medicinal plants, and more
Book Synopsis Anticancer plants: Properties and Application by : Mohd Sayeed Akhtar
Download or read book Anticancer plants: Properties and Application written by Mohd Sayeed Akhtar and published by Springer. This book was released on 2018-06-29 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is one of the leading death cause of human population increasingly seen in recent times. Plants have been used for medicinal purposes since immemorial times. Though, several synthetic medicines are useful in treating cancer, they are inefficient and unsafe. However, plants have proved to be useful in cancer cure. Moreover, natural compounds from plants and their derivatives are safe and effective in treatment and management of several cancer types. The anticancer plants such as Catharanthus roseus, Podophyllum peltatum, Taxus brevifolia, Camptotheca acuminate, Andrographis paniculata, Crateva nurvala, Croton tonkinensis, Oplopanax horridus etc., are important source of chemotherapeutic compounds. These plants have proven their significance in the treatment of cancer and various other infectious diseases. Nowadays, several well-known anticancer compounds such as taxol, podophyllotoxins, camptothecin, vinblastine, vincristine, homoharringtonine etc. have been isolated and purified from these medicinal plants. Many of them are used effectively to combat cancer and other related diseases. The herbal medicine and their products are the most suitable and safe to be used as an alternative medicine. Based on their traditional uses and experimental evidences, the anticancer products or compounds are isolated or extracted from the medicinally important plants. Many of these anticancer plants have become endangered due to ruthless harvesting in nature. Hence, there is a need to conserve these species and to propagate them in large scale using plant tissue culture. Alternatively, plant cell tissue and organ culture biotechnology can be adopted to produce these anticancer compounds without cultivation. The proper knowledge and exploration of these isolated molecules or products could provide an alternative source to reduce cancer risk, anti-tumorigenic properties, and suppression of carcinogen activities. Anticancer plants: Volume 1, Properties and Application is a very timely effort in this direction. Discussing the various types of anticancer plants as a source of curative agent, their pharmacological and neutraceutical properties, cryo-preservations and recent trends to understand the basic cause and consequences involved in the diseases diagnosis. We acknowledge the publisher, Springer for their continuous inspiration and valuable suggestions to improvise the content of this book. We further extend our heartfelt gratitude to all our book contributors for their support, and assistance to complete this assignment. I am sure that these books will benefit the scientific communities including academics, pharmaceuticals, nutraceuticals and medical practitioners.
Book Synopsis Protein Tyrosine Kinases by : Doriano Fabbro
Download or read book Protein Tyrosine Kinases written by Doriano Fabbro and published by Springer Science & Business Media. This book was released on 2007-11-13 with total page 599 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading researchers, from the Novartis group that pioneered Gleevec/GlivecTM and around the world, comprehensively survey the state of the art in the drug discovery processes (bio- and chemoinformatics, structural biology, profiling, generation of resistance, etc.) aimed at generating PTK inhibitors for the treatment of various diseases, including cancer. Highlights include a discussion of the rationale and the progress made towards generating "selective" low molecular-weight kinase inhibitors; an analysis of the normal function, role in disease, and application of platelet-derived growth factor antagonists; and a summary of the factors involved in successful structure-based drug design. Additional chapters address the advantages and disadvantages of in vivo preclinical models for testing protein kinase inhibitors with antitumor activity and the utility of different methods in the drug discovery and development process for determining "on-target" vs "off-target" effects of kinase inhibitors.
Book Synopsis Edible Medicinal And Non-Medicinal Plants by : T. K. Lim
Download or read book Edible Medicinal And Non-Medicinal Plants written by T. K. Lim and published by Springer Science & Business Media. This book was released on 2012-06-11 with total page 1037 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book continues as volume 4 of a multi-compendium on Edible Medicinal and Non-Medicinal Plants. It covers edible fruits/seeds used fresh or processed, as vegetables, spices, stimulants, edible oils and beverages. It encompasses selected species from the following families: Fagaceae, Grossulariaceae, Hypoxidaxeae, Myrsinaceae Olacaceae, Oleaceae, Orchidaceae, Oxalidaceae, Pandanaceae, Passifloraceae, Pedaliaceae, Phyllanthaceae, Pinaceae, Piperaceae, Rosaceae and Rutaceae . This work will be of significant interest to scientists, researchers, medical practitioners, pharmacologists, ethnobotanists, horticulturists, food nutritionists, agriculturists, botanists, conservationists, lecturers, students and the general public. Topics covered include: taxonomy; common/English and vernacular names; origin and distribution; agroecology; edible plant parts and uses; botany; nutritive and pharmacological properties, medicinal uses and research findings; nonedible uses; and selected references.
Book Synopsis Toxicological Profile for Nickel by : Syracuse Research Corporation
Download or read book Toxicological Profile for Nickel written by Syracuse Research Corporation and published by . This book was released on 2005 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt:
