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Modelisation Flexible Du Risque Devenements Iatrogenes Radio Induits
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Book Synopsis Modélisation flexible du risque d'événements iatrogènes radio-induits by : Mohamed Amine Benadjaoud
Download or read book Modélisation flexible du risque d'événements iatrogènes radio-induits written by Mohamed Amine Benadjaoud and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: La radiothérapie occupe une place majeure dans l'arsenal thérapeutique des cancers.Malgré des progrès technologiques importants depuis près de vingt ans, des tissus sains au voisinage ou à distance de la tumeur cible continuent à être inévitablement irradiés à des niveaux de doses très différents. Ces doses sont à l'origine d'effets secondaires précoces (Œdème, radionécrose, Dysphagie, Cystite) ou tardifs (rectorragies, télangiectasie, effets carcinogènes, les pathologie cérébrovasculaires).Il est donc primordial de quantifier et de prévenir ces effets secondaires afin d'améliorer la qualité de vie des patients pendant et après leur traitement.La modélisation du risque d'événements iatrogènes radio-induits repose sur la connaissance précise de la distribution de doses au tissu sain d'intérêt ainsi que sur un modèle de risque capable d'intégrer un maximum d'informations sur le profil d'irradiation et des autres facteurs de risques non dosimétriques. L'objectif de ce travail de thèse a été de développer des méthodes de modélisation capables de répondre à des questions spécifiques aux deux aspects, dosimétriques et statistiques, intervenant dans la modélisation du risque de survenue d'événements iatrogènes radio-induits.Nous nous sommes intéressé dans un premier temps au développement d'un modèle de calcul permettant de déterminer avec précision la dose à distance due au rayonnements de diffusion et de fuite lors d'un traitement par radiothérapie externe et ce, pour différentes tailles des champs et à différentes distances de l'axe du faisceau. Ensuite, nous avons utilisé des méthodes d'analyse de données fonctionnelles pour développer un modèle de risque de toxicité rectales après irradiation de la loge prostatique. Le modèle proposé a montré des performances supérieures aux modèles de risque existants particulièrement pour décrire le risque de toxicités rectales de grade 3. Dans le contexte d'une régression de Cox flexible sur données réelles, nous avons proposé une application originale des méthodes de statistique fonctionnelle permettant d'améliorer les performances d'une modélisation via fonctions B-splines de la relation dose-effet entre la dose de radiation à la thyroïde.Nous avons également proposé dans le domaine de la radiobiologie une méthodes basée sur l'analyse en composantes principales multiniveau pour quantifier la part de la variabilité expérimentale dans la variabilité des courbes de fluorescence mesurées.
Download or read book Hypnosis written by Léon Chertok and published by Pergamon. This book was released on 1966 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Dental Biomaterials by : Edward Sacher
Download or read book Dental Biomaterials written by Edward Sacher and published by World Scientific. This book was released on 2018-12-18 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: The contents of this book touch on the all major dental biomaterials: polymers, composites, ceramics and metals. The first part introduces the readers to the surface physicochemical and mechanical characterizations at the nanoscopic level, and the use of finite element analysis. The second part discusses dental adhesion, resin-based composites, polymerization contraction stress, impression materials and soft liners for total prosthesis. The third part deals with ceramics in restorative dentistry: zirconia and lithium disilicate, the fractography of dental ceramics, as well as bioglass for bone growth. The fourth part discusses the toxicity of mercury in dentistry, and the use of preventive materials for dental diseases. The concluding part identifies imminent techniques for dental biomaterials, such as additive manufacturing (3D printing), and bioprinting in dentistry.
Book Synopsis Mathematical Foundations of Network Analysis by : Paul Slepian
Download or read book Mathematical Foundations of Network Analysis written by Paul Slepian and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book we attempt to develop the fundamental results of resistive network analysis, based upon a sound mathematical structure. The axioms upon which our development is based are Ohm's Law, Kirchhoff's Voltage Law, and Kirchhoff's Current Law. In order to state these axioms precisely, and use them in the development of our network analysis, an elaborate mathematical structure is introduced, involving concepts of graph theory, linear algebra, and one dimensional algebraic topology. The graph theory and one dimensional algebraic topology used are developed from first principles; the reader needs no background in these subjects. However, we do assume that the reader has some familiarity with elementary linear algebra. It is now stylish to teach elementary linear algebra at the sophomore college level, and we feel that the require ment that the reader should be familiar with elementary linear algebra is no more demanding than the usual requirement in most electrical engineering texts that the reader should be familiar with calculus. In this book, however, no calculus is needed. Although no formal training in circuit theory is needed for an understanding of the book, such experience would certainly help the reader by presenting him with familiar examples relevant to the mathematical abstractions introduced. It is our intention in this book to exhibit the effect of the topological properties of the network upon the branch voltages and branch currents, the objects of interest in network analysis.
Book Synopsis Leptin and Reproduction by : Michael C. Henson
Download or read book Leptin and Reproduction written by Michael C. Henson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The isolation of leptin in 1994 and its characterization as a factor influencing appetite, energy balance, and adiposity, immediately thrust the polypeptide into the rapidly growing body of literature centered on the physiology of obesity. The growing clinical awareness of obesity as a major health risk in developed societies dovetailed perfectly with any of a number of roles that leptin might play in this abenant physiological condition. Almost unnoticed amidst the excitement generated by early leptin publications was the suggestion that the "fat hormone" might also regulate a wide range of systems and events important to reproduction, including pubertal development, gonadal endocrinology, fettility, and pregnancy. Recognizing this potential, a relatively small cadre of researchers began to examine leptin specifically as a reproductive hormone, thus creating a new and fertile field of investigation. Interest in this area has since gained momentum and an increased number of participants have now made significant contributions to our understanding of many leptin-related mechanisms that are relevant to reproductive biology. Leptin and Reproduction is the first major volume to specifically address leptin as a reproductive hormone and closely examines the advances made in the short time since this field of interest developed. Preeminent researchers ti'om many of the subdisciplines working within this area present a welcomed compendium of the wealth of related literature and voice novel interpretations of cun'ent advances.
Book Synopsis Side Effects of Drugs Annual by : Jeffrey K. Aronson
Download or read book Side Effects of Drugs Annual written by Jeffrey K. Aronson and published by Elsevier. This book was released on 2011-08-19 with total page 715 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Side Effects of Drugs Annual was first published in 1977. It has been continually published since then, as a yearly update to the voluminous encyclopedia Meyler's Side Effects of Drugs. Each new Annual continues to provide clinicians and medical investigators with a reliable and critical yearly survey of new data and trends in the area of Adverse Drug Reactions and Interactions. An international team of specialists has contributed to the Annuals by selecting critically from each year's writing all that is truly new and informative, by critically interpreting it, and by pointing to whatever is misleading. Provides a critical yearly survey of new data and trends Includes an essay that describes the modern approach to classifying adverse drug reactions Special reviews in this Annual include, among other topics: Antipsychotic drugs and now-onset diabetes mellitus, Treating asthma during pregnancy, and MMR vaccine and autism
Book Synopsis Hypnosis in Anaesthesiology by : Jean Lassner
Download or read book Hypnosis in Anaesthesiology written by Jean Lassner and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 58 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the First European Congress of Anesthesiology, held in Vienna, Austria, in September, 1962, panel discussions on nineteen different subjects were held, each lasting approxi mately three hours. One, concerning Controversial Aspects of Resuscitation, was later edited by its chairman, PETER SAFAR, and published in 1963. At the request of the publisher, the discussion on hypnosis has been edited in a similar manner. The participants in the discussion on Hypnosis in Anes thesiology had agreed, prior to the meeting, on a list of questions to be debated, and Dr. STOKVIS' introductory statement on the nature of hypnosis was circulated among them in appropriate translations in order to give the debate a starting point. It had also been agreed that no formal papers should be read after this introduction, and that the participants should use at will the German, English or French language. Following each contribution it was the chairman's task to give a brief summary in the two other languages. Discussion was therefore somewhat slowed down and occasionally rendered difficult by misunderstandings or the omission of details. Drs. GUEGUEN, MOSCONI, and VOLGYESI, who were not able. to attend, had sent written contributions which the chairman presented briefly during the discussion. The present text has been worked out of the tape recording of the discussion and the chairman's correspondence with the panelists some time after the meeting. Whenever the original contributions were in French or German, the English translation has been the chairman's.
Download or read book La Suggestibilite written by Alfred Binet and published by . This book was released on 2015-12-17 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Notice: This Book is published by Historical Books Limited (www.publicdomain.org.uk) as a Public Domain Book, if you have any inquiries, requests or need any help you can just send an email to [email protected] This book is found as a public domain and free book based on various online catalogs, if you think there are any problems regard copyright issues please contact us immediately via [email protected]
Book Synopsis The Pharmaceutical Industry by : Labour Party (Great Britain). Executive Committee
Download or read book The Pharmaceutical Industry written by Labour Party (Great Britain). Executive Committee and published by . This book was released on 1976 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Finite Graphs and Networks by : Robert G. Busacker
Download or read book Finite Graphs and Networks written by Robert G. Busacker and published by . This book was released on 1965 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Homoeopathic Pharmacy by : Steven B. Kayne
Download or read book Homoeopathic Pharmacy written by Steven B. Kayne and published by . This book was released on 1997 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Immunology of Human Reproduction by : James S. Scott
Download or read book Immunology of Human Reproduction written by James S. Scott and published by . This book was released on 1976 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Untoward Effects of Drugs by : Louis Lewin
Download or read book The Untoward Effects of Drugs written by Louis Lewin and published by . This book was released on 1905 with total page 1068 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Homeopathic Prescribing Pocket Companion by : Steven B. Kayne
Download or read book Homeopathic Prescribing Pocket Companion written by Steven B. Kayne and published by . This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A pocket book which offers the basic information that a pharmacist need regarding homeopathic remedies. It provides a general introduction on homoeopathy and the related disciplines of anthroposophy, Biochemic Salt and flower therapy.
Book Synopsis Side Effects of Drugs by : L. Meyler
Download or read book Side Effects of Drugs written by L. Meyler and published by . This book was released on 1952 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Issues and Reviews in Teratology by : Harold Kalter
Download or read book Issues and Reviews in Teratology written by Harold Kalter and published by Springer. This book was released on 2012-11-05 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Teratology is at once among the oldest and youngest of human preoccupations. Coincident with man's first observations of the stars were his recordings of human and animal deformities. But, such aberrancies must have occurred even earlier, for although it is one of those things-like evolution-that cannot be proven, it is nevertheless indisputable that dysmorphogenesis must have occurred from the time complex forms of life first arose on our planet; and that from the beginnings of human awareness our species was conscious of such happenings. From the earliest recordings of this fascination with the form and meaning of abnormality a tortuous but continuous line extends to modern struggles to understand and control these manifestations. And now, after long occupying an honorable but peripheral place in the halls of philosophical and scientific pursuits, teratology has quite suddenly come to take a prominent position at the hub of a complex crossroads of human concerns. This shift in its fortune has taken several forms. Fetal maldevelopment has become the concern of environmentalists, activists of various persuasions, indus trial organizations, government agencies, ethicists, parents-i. e. , individuals and groups whose actions are impelled by apprehension. Such motives are of course not without basis; the trauma of thalidomide left a scar yet raw. For still others clinicians, academics, experimentalists-the upsurge in the interest in fetal mal development is at a different level, and their pursuits are broad, taking external agents as but one of the causes of defective development.
Book Synopsis Complementary Therapies for Pharmacists by : Steven B. Kayne
Download or read book Complementary Therapies for Pharmacists written by Steven B. Kayne and published by . This book was released on 2002 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written for pharmacists, this is an introduction to the most commonly used complementary disciplines. The book covers theory, practical aspects and current scientific thinking.
