Modeling Ring Cleaving Dioxygenases

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Comprehensive Inorganic Chemistry II

Author :
Publisher : Newnes
ISBN 13 : 0080965296
Total Pages : 7694 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Comprehensive Inorganic Chemistry II by :

Download or read book Comprehensive Inorganic Chemistry II written by and published by Newnes. This book was released on 2013-07-23 with total page 7694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Inorganic Chemistry II, Nine Volume Set reviews and examines topics of relevance to today’s inorganic chemists. Covering more interdisciplinary and high impact areas, Comprehensive Inorganic Chemistry II includes biological inorganic chemistry, solid state chemistry, materials chemistry, and nanoscience. The work is designed to follow on, with a different viewpoint and format, from our 1973 work, Comprehensive Inorganic Chemistry, edited by Bailar, Emeléus, Nyholm, and Trotman-Dickenson, which has received over 2,000 citations. The new work will also complement other recent Elsevier works in this area, Comprehensive Coordination Chemistry and Comprehensive Organometallic Chemistry, to form a trio of works covering the whole of modern inorganic chemistry. Chapters are designed to provide a valuable, long-standing scientific resource for both advanced students new to an area and researchers who need further background or answers to a particular problem on the elements, their compounds, or applications. Chapters are written by teams of leading experts, under the guidance of the Volume Editors and the Editors-in-Chief. The articles are written at a level that allows undergraduate students to understand the material, while providing active researchers with a ready reference resource for information in the field. The chapters will not provide basic data on the elements, which is available from many sources (and the original work), but instead concentrate on applications of the elements and their compounds. Provides a comprehensive review which serves to put many advances in perspective and allows the reader to make connections to related fields, such as: biological inorganic chemistry, materials chemistry, solid state chemistry and nanoscience Inorganic chemistry is rapidly developing, which brings about the need for a reference resource such as this that summarise recent developments and simultaneously provide background information Forms the new definitive source for researchers interested in elements and their applications; completely replacing the highly cited first edition, which published in 1973

Microbial Models: From Environmental to Industrial Sustainability

Author : Susana Castro-Sowinski
Publisher : Springer
ISBN 13 : 981102555X
Total Pages : 350 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Microbial Models: From Environmental to Industrial Sustainability by : Susana Castro-Sowinski

Download or read book Microbial Models: From Environmental to Industrial Sustainability written by Susana Castro-Sowinski and published by Springer. This book was released on 2016-11-17 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes selected microbial genera from the perspective of their environmentally and commercially sustainable use. By focusing on their physiology and metabolism and combining historical information with the latest developments, it presents a multidisciplinary portrait of microbial sustainability. The chapters provide readers descriptions of each genus in the form of microbial models that move us closer to the goal of sustainability; selected chapters also include worldwide market information and lists of corresponding patents.

Microbial Degradation of Xenobiotics

Author : Shree Nath Singh
Publisher : Springer Science & Business Media
ISBN 13 : 3642237894
Total Pages : 488 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Microbial Degradation of Xenobiotics by : Shree Nath Singh

Download or read book Microbial Degradation of Xenobiotics written by Shree Nath Singh and published by Springer Science & Business Media. This book was released on 2011-10-07 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our interest in the microbial biodegradation of xenobiotics has increased many folds in recent years to find out sustainable ways for environmental cleanup. Bioremediation and biotransformation processes harness the naturally occurring ability of microbes to degrade, transform or accumulate a wide range of organic pollutants. Major methodological breakthroughs in recent years through detailed genomic, metagenomic, proteomic, bioinformatic and other high-throughput analyses of environmentally relevant microorganisms have provided us unprecedented insights into key biodegradative pathways and the ability of organisms to adapt to changing environmental conditions. The degradation of a wide spectrum of organic pollutants and wastes discharged into the environment by anthropogenic activities is an emerging need today to promote sustainable development of our society with low environmental impact. Microbial processes play a major role in the removal of recalcitrant compounds taking advantage of the astonishing catabolic versatility of microorganisms to degrade or transform such compounds. New breakthroughs in sequencing, genomics, proteomics, bioinformatics and imaging are generating vital information which opens a new era providing new insights of metabolic and regulatory networks, as well as clues to the evolution of degradation pathways and to the molecular adaptation strategies to changing environmental conditions. Functional genomic and metagenomic approaches are increasing our understanding of the relative importance of different pathways and regulatory networks to carbon flux in particular environments and for particular compounds. New approaches will certainly accelerate the development of bioremediation technologies and biotransformation processes in coming years for natural attenuation of contaminated environments

Translational Immunotherapy of Brain Tumors

Author : John H. Sampson
Publisher : Academic Press
ISBN 13 : 0128026251
Total Pages : 406 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Translational Immunotherapy of Brain Tumors by : John H. Sampson

Download or read book Translational Immunotherapy of Brain Tumors written by John H. Sampson and published by Academic Press. This book was released on 2017-02-06 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Immunotherapy of Brain Tumors gives researchers and practitioners an up-to-date and comprehensive overview of the field. Chapters include adoptive immunotherapy, immunosuppression, CAR therapy of brain tumors, and dendritic cell therapy for brain tumors. Very few agents have been shown to be efficacious in the treatment of malignant gliomas. Recently, there have been a number of studies demonstrating the potential success of immunotherapy for brain tumors. Immunotherapeutics are becoming the most frequent drugs to be used in cancer therapy. These new breakthroughs, now approved by the FDA, are a part of multiple phase III international trials and ongoing research in malignant glioma, meaning that the information in this cutting-edge book will be of great importance to practitioners and researchers alike. 2018 BMA Medical Book Awards Highly Commended in Oncology - Comprehensive overview, providing an update on immunology, translational immunotherapy, and clinical trials relating to malignant gliomas - Edited by a prominent neurosurgeon with contributions by leading researchers in the field - Ideal resource for researchers and practitioners interested in learning about mechanisms that use the immune system to treat brain tumors

Comprehensive Natural Products Chemistry

Author : Derek Barton
Publisher : Newnes
ISBN 13 : 0080912834
Total Pages : 8492 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Comprehensive Natural Products Chemistry by : Derek Barton

Download or read book Comprehensive Natural Products Chemistry written by Derek Barton and published by Newnes. This book was released on 1999-02-18 with total page 8492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Natural Products Chemistry

Iron-containing Enzymes

Author : Sam P. De Visser
Publisher : Royal Society of Chemistry
ISBN 13 : 1849731810
Total Pages : 463 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Iron-containing Enzymes by : Sam P. De Visser

Download or read book Iron-containing Enzymes written by Sam P. De Visser and published by Royal Society of Chemistry. This book was released on 2011 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mononuclear iron containing enzymes are important intermediates in bioprocesses and have potential in the industrial biosynthesis of specific products. This book features topical review chapters by leaders in this field and its various sub-disciplines.

Natural Product Biosynthesis

Author : Christopher T. Walsh
Publisher : Royal Society of Chemistry
ISBN 13 : 1788010760
Total Pages : 787 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Natural Product Biosynthesis by : Christopher T. Walsh

Download or read book Natural Product Biosynthesis written by Christopher T. Walsh and published by Royal Society of Chemistry. This book was released on 2017-04-28 with total page 787 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook describes the types of natural products, the biosynthetic pathways that enable the production of these molecules, and an update on the discovery of novel products in the post-genomic era.

Computational Modeling of Biological Systems

Author : Nikolay V Dokholyan
Publisher : Springer Science & Business Media
ISBN 13 : 1461421454
Total Pages : 360 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Computational Modeling of Biological Systems by : Nikolay V Dokholyan

Download or read book Computational Modeling of Biological Systems written by Nikolay V Dokholyan and published by Springer Science & Business Media. This book was released on 2012-02-12 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational modeling is emerging as a powerful new approach to study and manipulate biological systems. Multiple methods have been developed to model, visualize, and rationally alter systems at various length scales, starting from molecular modeling and design at atomic resolution to cellular pathways modeling and analysis. Higher time and length scale processes, such as molecular evolution, have also greatly benefited from new breeds of computational approaches. This book provides an overview of the established computational methods used for modeling biologically and medically relevant systems.

2-Oxoglutarate-Dependent Oxygenases

Author : Christopher Schofield
Publisher : Royal Society of Chemistry
ISBN 13 : 1782621954
Total Pages : 508 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis 2-Oxoglutarate-Dependent Oxygenases by : Christopher Schofield

Download or read book 2-Oxoglutarate-Dependent Oxygenases written by Christopher Schofield and published by Royal Society of Chemistry. This book was released on 2015-04-23 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery of the first examples of 2-oxoglutarate-dependent oxygenase-catalysed reactions in the 1960s, a remarkably broad diversity of alternate reactions and substrates has been revealed, and extensive advances have been achieved in our understanding of the structures and catalytic mechanisms. These enzymes are important agrochemical targets and are being pursued as therapeutic targets for a wide range of diseases including cancer and anemia. This book provides a central source of information that summarizes the key features of the essential group of 2-oxoglutarate-dependent dioxygenases and related enzymes. Given the numerous recent advances and biomedical interest in the field, this book aims to unite the latest research for those already working in the field as well as to provide an introduction for those newly approaching the topic, and for those interested in translating the basic science into medicinal and agricultural benefits. The book begins with four broad chapters that highlight critical aspects, including an overview of possible catalytic reactions, structures and mechanisms. The following seventeen chapters focus on carefully selected topics, each written by leading experts in the area. Readers will find explanations of rapidly evolving research, from the chemistry of isopenicillin N synthase to the oxidation mechanism of 5-methylcytosine in DNA by ten-eleven-translocase oxygenases.

Models for Mononuclear Nonheme Iron Proteins

Author : Yu-Min Catherine Chiou
Publisher :
ISBN 13 :
Total Pages : 534 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Models for Mononuclear Nonheme Iron Proteins by : Yu-Min Catherine Chiou

Download or read book Models for Mononuclear Nonheme Iron Proteins written by Yu-Min Catherine Chiou and published by . This book was released on 1994 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Oxygenases and Model Systems

Author : T. Funabiki
Publisher : Springer Science & Business Media
ISBN 13 : 9401154422
Total Pages : 403 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Oxygenases and Model Systems by : T. Funabiki

Download or read book Oxygenases and Model Systems written by T. Funabiki and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxygenases have been the subject of much study and are of great interest and application. Biomimetic chemistry of oxygenases has yielded clarification of enzyme structures and reaction mechanisms and has also led to the development of synthetic oxygenation processes. This volume contains 8 chapters written by leading researchers which together present an overview of di- and mono-oxygenases and their model systems from the point of view of functions, structures and mechanisms. An up-to-date clarification of structures around active centres of heme- and nonheme-oxygenases is given with reference to the design of model complexes. Various contributions also discuss in detail the formation, structure and reactivity of metal-oxygen and metal-substrate species in both enzyme and model systems. The contents of the volume address the interface between bioinorganic chemistry and homogeneous catalysis and contains much to emphasize the importance of catalytic studies in bio- and biomimetic chemistry. Audience: Research chemists interested in the use of oxygenases in catalysis.

Biomimetic Oxidations Catalyzed By Transition Metal Complexes

Author : Bernard Meunier
Publisher : World Scientific
ISBN 13 : 1783262389
Total Pages : 697 pages
Book Rating : 4.7/5 (832 download)

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Book Synopsis Biomimetic Oxidations Catalyzed By Transition Metal Complexes by : Bernard Meunier

Download or read book Biomimetic Oxidations Catalyzed By Transition Metal Complexes written by Bernard Meunier and published by World Scientific. This book was released on 2000-03-08 with total page 697 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the classic work Metal-Catalyzed Oxidations of Organic Compounds (edited by R A Sheldon and J K Kochi, 1991), no book has been devoted to advances in the field of biomimetic oxidations, which was created nearly 18 years ago. This expanding research field is covered in this volume. All the different aspects of the modeling of oxidations catalyzed by metalloenzymes are dealt with.This invaluable book will be useful to postgraduates as well as researchers in academia and industry, and will also benefit second year university students.

Metalloenzymes

Author : Claudiu T. Supuran
Publisher : Elsevier
ISBN 13 : 0128242353
Total Pages : 636 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Metalloenzymes by : Claudiu T. Supuran

Download or read book Metalloenzymes written by Claudiu T. Supuran and published by Elsevier. This book was released on 2023-08-30 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metalloenzymes: From Bench to Bedside offers a thorough overview of metalloenzymes, spanning biochemical and structural features, pharmacology, and biotechnological applications. After a brief overview, international experts in the field discuss a wide range of magnesium, calcium, zinc, manganese, nickel, iron, copper, cadmium, molybdenum, and tungsten enzymes, along with catalytic roles within their active sites. With a uniform approach throughout, each chapter includes the structure and function of the enzyme, physiologic and pathologic roles, inhibitors and activators of the enzyme (and their design), and clinical agents or compounds applied in medicine and drug discovery. This book enables scientists across academia and industry to adopt ongoing metalloenzyme research, and continuous discovery of novel metalloenzymes, in new life science studies and clinical applications. - Examines a range of metalloenzymes, from biochemistry to pharmacology and drug design - Each chapter examines enzyme structure and function, physiologic and pathologic roles, inhibitors and activators, and clinical application - Features chapter contributions from international experts in the field

Enzymatic Reaction Mechanisms

Author : Perry A. Frey
Publisher : Oxford University Press
ISBN 13 : 0195352742
Total Pages : 852 pages
Book Rating : 4.1/5 (953 download)

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Book Synopsis Enzymatic Reaction Mechanisms by : Perry A. Frey

Download or read book Enzymatic Reaction Mechanisms written by Perry A. Frey and published by Oxford University Press. This book was released on 2007-01-27 with total page 852 pages. Available in PDF, EPUB and Kindle. Book excerpt: Books dealing with the mechanisms of enzymatic reactions were written a generation ago. They included volumes entitled Bioorganic Mechanisms, I and II by T.C. Bruice and S.J. Benkovic, published in 1965, the volume entitled Catalysis in Chemistry and Enzymology by W.P. Jencks in 1969, and the volume entitled Enzymatic Reaction Mechanisms by C.T. Walsh in 1979. The Walsh book was based on the course taught by W.P. Jencks and R.H. Abeles at Brandeis University in the 1960's and 1970's. By the late 1970's, much more could be included about the structures of enzymes and the kinetics and mechanisms of enzymatic reactions themselves, and less emphasis was placed on chemical models. Walshs book was widely used in courses on enzymatic mechanisms for many years. Much has happened in the field of mechanistic enzymology in the past 15 to 20 years. Walshs book is both out-of-date and out-of-focus in todays world of enzymatic mechanisms. There is no longer a single volume or a small collection of volumes to which students can be directed to obtain a clear understanding of the state of knowledge regarding the chemicals mechanisms by which enzymes catalyze biological reactions. There is no single volume to which medicinal chemists and biotechnologists can refer on the subject of enzymatic mechanisms. Practitioners in the field have recognized a need for a new book on enzymatic mechanisms for more than ten years, and several, including Walsh, have considered undertaking to modernize Walshs book. However, these good intentions have been abandoned for one reason or another. The great size of the knowledge base in mechanistic enzymology has been a deterrent. It seems too large a subject for a single author, and it is difficult for several authors to coordinate their work to mutual satisfaction. This text by Perry A. Frey and Adrian D. Hegeman accomplishes this feat, producing the long-awaited replacement for Walshs classic text.

Oxygen Atom Transfer Reactions

Author : Robert Bakhtchadjian
Publisher : Bentham Science Publishers
ISBN 13 : 9815050931
Total Pages : 137 pages
Book Rating : 4.8/5 (15 download)

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Book Synopsis Oxygen Atom Transfer Reactions by : Robert Bakhtchadjian

Download or read book Oxygen Atom Transfer Reactions written by Robert Bakhtchadjian and published by Bentham Science Publishers. This book was released on 2023-01-11 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces readers to the fundamentals of oxygen atom transfer reactions. It also gives mechanistic insights into the redox processes occurring through the oxygen atom transfer reactions. It also includes information about catalytic activation of oxygen through enzymes and oxo-metallic complexes. All topics are explored in separate chapters. Key features: - reviews the basic mechanisms in redox processes involving oxo-atom transfer reactions. - presents progress in the biomimetic activation of dioxygen related to the catalytic oxidations by synthetic metal organic complexes. - covers an important class of metal-organic compounds - nickel-oxygen species - generated in catalytic oxidation processes as oxygen atom transfer agents. - explains the mechanistic aspects of the heterogeneous photochemical redox processes via oxo-atom transfer reactions - provides references for further reading It is a reference for both professional scientists in the fields of chemistry, biology and applied sciences, and for graduate and undergraduate students interested in understanding reaction mechanisms involving oxygen.

Biotechnological Production and Conversion of Aromatic Compounds and Natural Products

Author : Nils Jonathan Helmuth Averesch
Publisher : Frontiers Media SA
ISBN 13 : 2889639134
Total Pages : 148 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Biotechnological Production and Conversion of Aromatic Compounds and Natural Products by : Nils Jonathan Helmuth Averesch

Download or read book Biotechnological Production and Conversion of Aromatic Compounds and Natural Products written by Nils Jonathan Helmuth Averesch and published by Frontiers Media SA. This book was released on 2020-07-31 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biocatalysis

Author : Qayyum Husain
Publisher : Springer Nature
ISBN 13 : 3030250237
Total Pages : 341 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Biocatalysis by : Qayyum Husain

Download or read book Biocatalysis written by Qayyum Husain and published by Springer Nature. This book was released on 2019-09-03 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces readers to industrially important enzymes and discusses in detail their structures and functions, as well as their manifold applications. Due to their selective biocatalytic capabilities, enzymes are used in a broad range of industries and processes. The book highlights selected enzymes and their applications in agriculture, food processing and discoloration, as well as their role in biomedicine. In turn, it discusses biochemical engineering strategies such as enzyme immobilization, metabolic engineering, and cross-linkage of enzyme aggregates, and critically weighs their pros and cons. Offering a wealth of information, and stimulating further research by presenting new concepts on enzymatic catalytic functions in basic and applied contexts, the book represents a valuable asset for researchers from academia and industry who are engaged in biochemical engineering, microbiology and biotechnology.