Modeling of Physiological Flows

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Publisher : Springer Science & Business Media
ISBN 13 : 8847019354
Total Pages : 418 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis Modeling of Physiological Flows by : Davide Ambrosi

Download or read book Modeling of Physiological Flows written by Davide Ambrosi and published by Springer Science & Business Media. This book was released on 2012-10-31 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a mathematical update of the state of the art of the research in the field of mathematical and numerical models of the circulatory system. It is structured into different chapters, written by outstanding experts in the field. Many fundamental issues are considered, such as: the mathematical representation of vascular geometries extracted from medical images, modelling blood rheology and the complex multilayer structure of the vascular tissue, and its possible pathologies, the mechanical and chemical interaction between blood and vascular walls, and the different scales coupling local and systemic dynamics. All of these topics introduce challenging mathematical and numerical problems, demanding for advanced analysis and efficient simulation techniques, and pay constant attention to applications of relevant clinical interest. This book is addressed to graduate students and researchers in the field of bioengineering, applied mathematics and medicine, wishing to engage themselves in the fascinating task of modeling the cardiovascular system or, more broadly, physiological flows.

Applied Mathematical Models in Human Physiology

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Publisher : SIAM
ISBN 13 : 0898715393
Total Pages : 304 pages
Book Rating : 4.8/5 (987 download)

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Book Synopsis Applied Mathematical Models in Human Physiology by : Johnny T. Ottesen

Download or read book Applied Mathematical Models in Human Physiology written by Johnny T. Ottesen and published by SIAM. This book was released on 2004-02-01 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces mathematicians to real applications from physiology. Using mathematics to analyze physiological systems, the authors discuss models reflecting current research in cardiovascular and pulmonary physiology. In particular, they present models describing blood flow in the heart and the cardiovascular system, as well as the transport of oxygen and carbon dioxide through the respiratory system and a model for baroreceptor regulation. This is the only book available that analyzes up-to-date models of the physiological system at several levels of detail; both simple 'real-time' models that can be directly used in larger systems, and more detailed 'reference' models that show the underlying physiological mechanisms and provide parameters for and validation of simpler models. The book also covers two-dimensional modeling of the fluid dynamics in the heart and its ability to pump, and includes a discussion of modeling wave-propagation throughout the systemic arteries.

Mathematical and Computer Modeling of Physiological Systems

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Publisher :
ISBN 13 :
Total Pages : 296 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Mathematical and Computer Modeling of Physiological Systems by : Vincent C. Rideout

Download or read book Mathematical and Computer Modeling of Physiological Systems written by Vincent C. Rideout and published by . This book was released on 1991 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Computer Code for Modeling Physiological Flows

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Author :
Publisher :
ISBN 13 :
Total Pages : 376 pages
Book Rating : 4.:/5 (57 download)

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Book Synopsis A Computer Code for Modeling Physiological Flows by : Byron Lavon Hansen

Download or read book A Computer Code for Modeling Physiological Flows written by Byron Lavon Hansen and published by . This book was released on 2002 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Wall-Fluid Interactions in Physiological Flows

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Publisher : WIT Press
ISBN 13 : 1853128996
Total Pages : 205 pages
Book Rating : 4.8/5 (531 download)

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Book Synopsis Wall-Fluid Interactions in Physiological Flows by : M.W. Collins

Download or read book Wall-Fluid Interactions in Physiological Flows written by M.W. Collins and published by WIT Press. This book was released on 2004-05-19 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: All fluid flow problems in the human body involve interaction with the vessel wall. This volume presents a number of studies where primarily mathematical modelling has been applied to a variety of medical wall-fluid interaction problems. The medical applications discussed are highly varied, while some key clinical areas are also addressed. Unusually, a number of important medical challenges involving fluid flow are considered in combination with the relevant solid mechanics. The complexity of addressing combined fluid flow and solid behaviour is viewed positively by the book’s distinguished contributors. For the researcher it offers new scope for developing and demonstrating a mastery of the scientific principles involved.

Physics, Pharmacology and Physiology for Anaesthetists

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Publisher : Cambridge University Press
ISBN 13 : 1107615887
Total Pages : 439 pages
Book Rating : 4.1/5 (76 download)

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Book Synopsis Physics, Pharmacology and Physiology for Anaesthetists by : Matthew E. Cross

Download or read book Physics, Pharmacology and Physiology for Anaesthetists written by Matthew E. Cross and published by Cambridge University Press. This book was released on 2014-03-06 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: A quick reference to basic science for anaesthetists, containing all the key information needed for FRCA exams.

Hemodynamical Flows

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Publisher : Springer Science & Business Media
ISBN 13 : 3764378069
Total Pages : 512 pages
Book Rating : 4.7/5 (643 download)

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Book Synopsis Hemodynamical Flows by : Giovanni P. Galdi

Download or read book Hemodynamical Flows written by Giovanni P. Galdi and published by Springer Science & Business Media. This book was released on 2008-04-17 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book surveys research results on the physical and mathematical modeling, as well as the numerical simulation of complex fluid and structural mechanical processes occurring in the human blood circulation system. Topics treated include continuum mechanical description; choice of suitable liquid and wall models; mathematical analysis of coupled models; numerical methods for flow simulation; parameter identification and model calibration; fluid-solid interaction; mathematical analysis of piping systems; particle transport in channels and pipes; artificial boundary conditions, and many more. The book was developed from lectures presented by the authors at the Oberwolfach Research Institute (MFO), in Oberwolfach-Walke, Germany, November, 2005.

Mathematical Modeling and Validation in Physiology

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Author :
Publisher : Springer
ISBN 13 : 3642328822
Total Pages : 270 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Mathematical Modeling and Validation in Physiology by : Jerry J. Batzel

Download or read book Mathematical Modeling and Validation in Physiology written by Jerry J. Batzel and published by Springer. This book was released on 2012-12-14 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume synthesizes theoretical and practical aspects of both the mathematical and life science viewpoints needed for modeling of the cardiovascular-respiratory system specifically and physiological systems generally. Theoretical points include model design, model complexity and validation in the light of available data, as well as control theory approaches to feedback delay and Kalman filter applications to parameter identification. State of the art approaches using parameter sensitivity are discussed for enhancing model identifiability through joint analysis of model structure and data. Practical examples illustrate model development at various levels of complexity based on given physiological information. The sensitivity-based approaches for examining model identifiability are illustrated by means of specific modeling examples. The themes presented address the current problem of patient-specific model adaptation in the clinical setting, where data is typically limited.

Simulation of Physiological Flows

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Publisher :
ISBN 13 :
Total Pages : 146 pages
Book Rating : 4.:/5 (891 download)

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Book Synopsis Simulation of Physiological Flows by : Alejandro Roldán-Alzate

Download or read book Simulation of Physiological Flows written by Alejandro Roldán-Alzate and published by . This book was released on 2008 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biology and Mechanics of Blood Flows

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Publisher : Springer Science & Business Media
ISBN 13 : 0387748490
Total Pages : 468 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Biology and Mechanics of Blood Flows by : Marc Thiriet

Download or read book Biology and Mechanics of Blood Flows written by Marc Thiriet and published by Springer Science & Business Media. This book was released on 2007-12-20 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative book presents the basic knowledge and state-of-the-art techniques necessary to carry out investigations of the cardiovascular system using modeling and simulation. This volume contains chapters on anatomy, physiology, continuum mechanics, as well as pathological changes in the vasculature walls including the heart and their treatments. Methods of numerical simulations are given and illustrated in particular by application to wall diseases.

Modelling Methodology for Physiology and Medicine

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Author :
Publisher : Newnes
ISBN 13 : 0124095259
Total Pages : 589 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Modelling Methodology for Physiology and Medicine by : Ewart Carson

Download or read book Modelling Methodology for Physiology and Medicine written by Ewart Carson and published by Newnes. This book was released on 2013-12-05 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modelling Methodology for Physiology and Medicine, Second Edition, offers a unique approach and an unprecedented range of coverage of the state-of-the-art, advanced modeling methodology that is widely applicable to physiology and medicine. The second edition, which is completely updated and expanded, opens with a clear and integrated treatment of advanced methodology for developing mathematical models of physiology and medical systems. Readers are then shown how to apply this methodology beneficially to real-world problems in physiology and medicine, such as circulation and respiration. The focus of Modelling Methodology for Physiology and Medicine, Second Edition, is the methodology that underpins good modeling practice. It builds upon the idea of an integrated methodology for the development and testing of mathematical models. It covers many specific areas of methodology in which important advances have taken place over recent years and illustrates the application of good methodological practice in key areas of physiology and medicine. It builds on work that the editors have carried out over the past 30 years, working in cooperation with leading practitioners in the field. - Builds upon and enhances the reader's existing knowledge of modeling methodology and practice - Editors are internationally renowned leaders in their respective fields - Provides an understanding of modeling methodologies that can address real problems in physiology and medicine and achieve results that are beneficial either in advancing research or in providing solutions to clinical problems

Three-dimensional Physiological Flow Simulation on Multi-box Computational Domains

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (544 download)

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Book Synopsis Three-dimensional Physiological Flow Simulation on Multi-box Computational Domains by :

Download or read book Three-dimensional Physiological Flow Simulation on Multi-box Computational Domains written by and published by . This book was released on 2003 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The fluid flow phenomena in biological systems are typically complex. The complexity is originated from, for example, non-Newtonian behavior of body fluids, complicated geometry, as well as the interaction of muscle and fluid. With the advent of modern computational technology, both in hardware and software, gradually these problems can be resolved. The present research illustrates two such examples. Grid generation is a branch of applied mathematics that is essential for conducting numerical simulation of fluid flow. In this research, a new grid generation technique is developed and implemented in a flow solver. This technique enables one to perform grid generation for complex geometry using only a single computational zone. Fluid flow can then be analyzed without iteration between zones. The scheme is based on the composite transformation of an algebraic mapping and a mapping governed by the Laplace equation. The governing equations for the grid generation are derived first and then solved numerically. The scheme used for solving the grid generating equations is an extension of the traditional three-dimensional Douglass-Gunn scheme. Areas of extension include the inclusion of mixed derivative terms as well as first-order derivative terms. A unique feature of the proposed grid generation scheme is the concept of multi-box computational domains. In this scheme, the physical domain is mapped onto a geometry composed of many boxes in the computational space, rather than a single box as the traditional method does. The numerical solution routine is adjusted accordingly to accommodate this new feature. Grids were generated for two model geometries using the proposed grid generation software. The graft model features one inflow conduit and two outflow conduits, while the left atrium (LA) model has four inflow conduits and one outflow conduit. Flow simulation was performed using the research code INS3D, which employs the method of artificial compressibility. This method transforms the Navier-Stokes equations into a hyperbolic-parabolic set by adding to them pseudo-pressure gradient terms. The scheme is then marched along the pseudo-time axis, until the velocity field becomes divergence-free. For the flow simulation in side the graft, the effect of Reynolds number and flow-division ratio is examined ... In summary, the present research demonstrates applications of computational fluid dynamics technique in the analysis of flow in biological system. A new grid generation technique is realized, and proved to be very useful in simulating these flows. Flow simulation results provide insights into the system and may be of use for clinic reference.

Introduction to Modeling in Physiology and Medicine

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Publisher : Academic Press
ISBN 13 : 0128158050
Total Pages : 384 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Introduction to Modeling in Physiology and Medicine by : Claudio Cobelli

Download or read book Introduction to Modeling in Physiology and Medicine written by Claudio Cobelli and published by Academic Press. This book was released on 2019-08-01 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Modeling in Physiology and Medicine, Second Edition, develops a clear understanding of the fundamental principles of good modeling methodology. Sections show how to create valid mathematical models that are fit for a range of purposes. These models are supported by detailed explanation, extensive case studies, examples and applications. This updated edition includes clearer guidance on the mathematical prerequisites needed to achieve the maximum benefit from the material, a greater detail regarding basic approaches to modeling, and discussions on non-linear and stochastic modeling. The range of case study material has been substantially extended, with examples drawn from recent research experience. Key examples include a cellular model of insulin secretion and its extension to the whole-body level, a model of insulin action during a meal/oral glucose tolerance test, a large-scale simulation model of type 1 diabetes and its use in in silico clinical trials and drug trials. Covers the underlying principles of good quantitative modeling methodology, with applied biomedical engineering and bioscience examples to ensure relevance to students, current research and clinical practice Includes modeling data, modeling systems, linear and non-linear systems, model identification, parametric and non-parametric models, and model validation Presents clear, step-by-step working plus examples and extensive case studies that relate concepts to real world applications Provides end-of-chapter exercises and assignments to reinforce learning

Signals and Systems in Biomedical Engineering

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Publisher : Springer Science & Business Media
ISBN 13 : 1461542995
Total Pages : 348 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Signals and Systems in Biomedical Engineering by : Suresh R. Devasahayam

Download or read book Signals and Systems in Biomedical Engineering written by Suresh R. Devasahayam and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past few years Biomedical Engineering has received a great deal of attention as one of the emerging technologies in the last decade and for years to come, as witnessed by the many books, conferences, and their proceedings. Media attention, due to the applications-oriented advances in Biomedical Engineering, has also increased. Much of the excitement comes from the fact that technology is rapidly changing and new technological adventures become available and feasible every day. For many years the physical sciences contributed to medicine in the form of expertise in radiology and slow but steady contributions to other more diverse fields, such as computers in surgery and diagnosis, neurology, cardiology, vision and visual prosthesis, audition and hearing aids, artificial limbs, biomechanics, and biomaterials. The list goes on. It is therefore hard for a person unfamiliar with a subject to separate the substance from the hype. Many of the applications of Biomedical Engineering are rather complex and difficult to understand even by the not so novice in the field. Much of the hardware and software tools available are either too simplistic to be useful or too complicated to be understood and applied. In addition, the lack of a common language between engineers and computer scientists and their counterparts in the medical profession, sometimes becomes a barrier to progress.

Tissue Functioning and Remodeling in the Circulatory and Ventilatory Systems

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Publisher : Springer Science & Business Media
ISBN 13 : 1461459664
Total Pages : 976 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Tissue Functioning and Remodeling in the Circulatory and Ventilatory Systems by : Marc Thiriet

Download or read book Tissue Functioning and Remodeling in the Circulatory and Ventilatory Systems written by Marc Thiriet and published by Springer Science & Business Media. This book was released on 2013-01-11 with total page 976 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. Volume 5 is devoted to cells, tissues, and organs of the cardiovascular and ventilatory systems with an emphasis on mechanotransduction-based regulation of flow. The blood vessel wall is a living tissue that quickly reacts to loads applied on it by the flowing blood. In any segment of a blood vessel, the endothelial and smooth muscle cells can sense unusual time variations in small-magnitude wall shear stress and large-amplitude wall stretch generated by abnormal hemodynamic stresses. These cells respond with a short-time scale (from seconds to hours) to adapt the vessel caliber. Since such adaptive cell activities can be described using mathematical models, a key objective of this volume is to identify the mesoscopic agents and nanoscopic mediators required to derive adequate mathematical models. The resulting biomathematical models and corresponding simulation software can be incorporated into platforms developed in virtual physiology for improved understanding and training.

Mathematical Modeling of Unsteady Inviscid Flows

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Publisher : Springer
ISBN 13 : 303018319X
Total Pages : 461 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Mathematical Modeling of Unsteady Inviscid Flows by : Jeff D. Eldredge

Download or read book Mathematical Modeling of Unsteady Inviscid Flows written by Jeff D. Eldredge and published by Springer. This book was released on 2019-07-22 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book builds inviscid flow analysis from an undergraduate-level treatment of potential flow to the level required for research. The tools covered in this book allow the reader to develop physics-based mathematical models for a variety of flows, including attached and separated flows past wings, fins, and blades of various shapes undergoing arbitrary motions. The book covers all of the ingredients of these models: the solution of potential flows about arbitrary body shapes in two- and three-dimensional contexts, with a particular focus on conformal mapping in the plane; the decomposition of the flow into contributions from ambient vorticity and body motion; generalized edge conditions, of which the Kutta condition is a special case; and the calculation of force and moment, with extensive treatments of added mass and the influence of fluid vorticity. The book also contains an extensive primer with all of the necessary mathematical tools. The concepts are demonstrated on several example problems, both classical and modern.

Control of Cell Fate in the Circulatory and Ventilatory Systems

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Publisher : Springer Science & Business Media
ISBN 13 : 1461403294
Total Pages : 540 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Control of Cell Fate in the Circulatory and Ventilatory Systems by : Marc Thiriet

Download or read book Control of Cell Fate in the Circulatory and Ventilatory Systems written by Marc Thiriet and published by Springer Science & Business Media. This book was released on 2011-11-01 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to nano- and microscopic events in a corrector scheme of regulated mechanisms. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning. Volumes 1 and 2 are devoted to cell organization and fate, as well as activities that are autoregulated and/or controlled by the cell environment. Volume 1 examined cellular features that allow adaptation to environmental conditions. Volume 2 begins with a survey of the cell types of the nervous and endocrine systems involved in the regulation of the vasculature and respiratory tract and growth factors. It then describes major cell events in the circulatory and ventilatory systems, such as cell growth, proliferation, migration, and death. Circadian cycles that drive rhythmic gene transcription are also covered.