Modeling Dynamic Phenomena in Molecular and Cellular Biology

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Publisher : Cambridge University Press
ISBN 13 : 9780521274777
Total Pages : 326 pages
Book Rating : 4.2/5 (747 download)

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Book Synopsis Modeling Dynamic Phenomena in Molecular and Cellular Biology by : Lee A. Segel

Download or read book Modeling Dynamic Phenomena in Molecular and Cellular Biology written by Lee A. Segel and published by Cambridge University Press. This book was released on 1984-03-30 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: The dynamic development of various processes is a central problem of biology and indeed of all the sciences. The mathematics describing that development is, in general, complicated, because the models that are realistic are usually nonlinear. Consequently many biologists may not notice a possible application of theory. They may be unable to decide whether a particular model captures the essence of a system, or to appreciate that analysis of a model can reveal important aspects of biological problems and may even describe in detail how a system works. The aim of this textbook is to remedy the situation by adopting a general approach to model analysis and applying it several times to problems (drawn primarily from molecular and cellular biology) of gradually increasing biological and mathematical complexity. Although material of considerable sophistication is included, little mathematical background is required - only some exposure to elementary calculus; appendixes supply the necessary mathematics and the author concentrates on concepts rather than techniques. He also emphasizes the role of computers in giving a full picture of model behavior and complementing more qualitative analysis. Some problems suitable for computer analysis are also included. This is a class-tested textbook suitable for a one-semester course for advanced undergraduate and beginning graduate students in biology or applied mathematics. It can also be used as a source book for teachers and a reference for specialists.

Quantitative Fundamentals of Molecular and Cellular Bioengineering

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Publisher : MIT Press
ISBN 13 : 0262042657
Total Pages : 593 pages
Book Rating : 4.2/5 (62 download)

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Book Synopsis Quantitative Fundamentals of Molecular and Cellular Bioengineering by : K. Dane Wittrup

Download or read book Quantitative Fundamentals of Molecular and Cellular Bioengineering written by K. Dane Wittrup and published by MIT Press. This book was released on 2020-01-07 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive presentation of essential topics for biological engineers, focusing on the development and application of dynamic models of biomolecular and cellular phenomena. This book describes the fundamental molecular and cellular events responsible for biological function, develops models to study biomolecular and cellular phenomena, and shows, with examples, how models are applied in the design and interpretation of experiments on biological systems. Integrating molecular cell biology with quantitative engineering analysis and design, it is the first textbook to offer a comprehensive presentation of these essential topics for chemical and biological engineering. The book systematically develops the concepts necessary to understand and study complex biological phenomena, moving from the simplest elements at the smallest scale and progressively adding complexity at the cellular organizational level, focusing on experimental testing of mechanistic hypotheses. After introducing the motivations for formulation of mathematical rate process models in biology, the text goes on to cover such topics as noncovalent binding interactions; quantitative descriptions of the transient, steady state, and equilibrium interactions of proteins and their ligands; enzyme kinetics; gene expression and protein trafficking; network dynamics; quantitative descriptions of growth dynamics; coupled transport and reaction; and discrete stochastic processes. The textbook is intended for advanced undergraduate and graduate courses in chemical engineering and bioengineering, and has been developed by the authors for classes they teach at MIT and the University of Minnesota.

Dynamical Systems for Biological Modeling

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Publisher : CRC Press
ISBN 13 : 1498774040
Total Pages : 482 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Dynamical Systems for Biological Modeling by : Fred Brauer

Download or read book Dynamical Systems for Biological Modeling written by Fred Brauer and published by CRC Press. This book was released on 2015-12-23 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dynamical Systems for Biological Modeling: An Introduction prepares both biology and mathematics students with the understanding and techniques necessary to undertake basic modeling of biological systems. It achieves this through the development and analysis of dynamical systems.The approach emphasizes qualitative ideas rather than explicit computa

Cellular Biophysics and Modeling

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Publisher : Cambridge University Press
ISBN 13 : 1107005361
Total Pages : 395 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Cellular Biophysics and Modeling by : Greg Conradi Smith

Download or read book Cellular Biophysics and Modeling written by Greg Conradi Smith and published by Cambridge University Press. This book was released on 2019-03-14 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: What every neuroscientist should know about the mathematical modeling of excitable cells, presented at an introductory level.

Mathematical Models in Biology

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Publisher : SIAM
ISBN 13 : 9780898719147
Total Pages : 629 pages
Book Rating : 4.7/5 (191 download)

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Book Synopsis Mathematical Models in Biology by : Leah Edelstein-Keshet

Download or read book Mathematical Models in Biology written by Leah Edelstein-Keshet and published by SIAM. This book was released on 1988-01-01 with total page 629 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical Models in Biology is an introductory book for readers interested in biological applications of mathematics and modeling in biology. A favorite in the mathematical biology community, it shows how relatively simple mathematics can be applied to a variety of models to draw interesting conclusions. Connections are made between diverse biological examples linked by common mathematical themes. A variety of discrete and continuous ordinary and partial differential equation models are explored. Although great advances have taken place in many of the topics covered, the simple lessons contained in this book are still important and informative. Audience: the book does not assume too much background knowledge--essentially some calculus and high-school algebra. It was originally written with third- and fourth-year undergraduate mathematical-biology majors in mind; however, it was picked up by beginning graduate students as well as researchers in math (and some in biology) who wanted to learn about this field.

Advances in Systems Biology

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Publisher : Springer Science & Business Media
ISBN 13 : 1441972102
Total Pages : 679 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Advances in Systems Biology by : Igor I. Goryanin

Download or read book Advances in Systems Biology written by Igor I. Goryanin and published by Springer Science & Business Media. This book was released on 2011-12-09 with total page 679 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Society for Systems Biology (ISSB) is a society aimed at advancing world-wide systems biology research by providing a forum for scientific discussions and various academic services. The ISSB helps coordinate researchers to form alliances for meeting the unique needs of multidisciplinary and international systems biology research. The annual International Conference on Systems Biology (ICSB) serves as the main meeting for the society and is one of the largest academic and commercial gatherings under the broad heading of ‘Systems Biology’.

Modeling Biomolecular Networks in Cells

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Publisher : Springer Science & Business Media
ISBN 13 : 1849962146
Total Pages : 343 pages
Book Rating : 4.8/5 (499 download)

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Book Synopsis Modeling Biomolecular Networks in Cells by : Luonan Chen

Download or read book Modeling Biomolecular Networks in Cells written by Luonan Chen and published by Springer Science & Business Media. This book was released on 2010-07-05 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modeling Biomolecular Networks in Cells shows how the interaction between the molecular components of basic living organisms can be modelled mathematically and the models used to create artificial biological entities within cells. Such forward engineering is a difficult task but the nonlinear dynamical methods espoused in this book simplify the biology so that it can be successfully understood and the synthesis of simple biological oscillators and rhythm-generators made feasible. Such simple units can then be co-ordinated using intercellular signal biomolecules. The formation of such man-made multicellular networks with a view to the production of biosensors, logic gates, new forms of integrated circuitry based on "gene-chips" and even biological computers is an important step in the design of faster and more flexible "electronics". The book also provides theoretical frameworks and tools with which to analyze the nonlinear dynamical phenomena which arise from the connection of building units in a biomolecular network.

A Course in Mathematical Biology

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Publisher : SIAM
ISBN 13 : 0898718252
Total Pages : 307 pages
Book Rating : 4.8/5 (987 download)

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Book Synopsis A Course in Mathematical Biology by : Gerda de Vries

Download or read book A Course in Mathematical Biology written by Gerda de Vries and published by SIAM. This book was released on 2006-07-01 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the only book that teaches all aspects of modern mathematical modeling and that is specifically designed to introduce undergraduate students to problem solving in the context of biology. Included is an integrated package of theoretical modeling and analysis tools, computational modeling techniques, and parameter estimation and model validation methods, with a focus on integrating analytical and computational tools in the modeling of biological processes. Divided into three parts, it covers basic analytical modeling techniques; introduces computational tools used in the modeling of biological problems; and includes various problems from epidemiology, ecology, and physiology. All chapters include realistic biological examples, including many exercises related to biological questions. In addition, 25 open-ended research projects are provided, suitable for students. An accompanying Web site contains solutions and a tutorial for the implementation of the computational modeling techniques. Calculations can be done in modern computing languages such as Maple, Mathematica, and MATLAB?.

Mathematical Modelling

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Publisher : SIAM
ISBN 13 : 0898712041
Total Pages : 346 pages
Book Rating : 4.8/5 (987 download)

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Book Synopsis Mathematical Modelling by : Murray S. Klamkin

Download or read book Mathematical Modelling written by Murray S. Klamkin and published by SIAM. This book was released on 1987-01-01 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematics of Computing -- Miscellaneous.

Synthetic Biology

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Publisher : John Wiley & Sons
ISBN 13 : 3527668551
Total Pages : 762 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Synthetic Biology by : Robert A. Meyers

Download or read book Synthetic Biology written by Robert A. Meyers and published by John Wiley & Sons. This book was released on 2015-05-18 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: These two volumes contain a selection of updated articles from the acclaimed Meyers Encyclopedia of Molecular Cell Biology and Molecular Medicine, the most authoritative resource in cell and molecular biology, combined with new articles by "founding fathers" in the field. The work is divided into six sections: + Biological Basis + Modeling + Modular Parts and Circuits + Synthetic Genomes + Diseases and Therapeutics + Chemicals Production. Ideally suited as advanced reading for students and postdocs, and with all current research trends covered by an impressive number of leading figures in the field, this is the first choice reference for research institutions.

Dynamical Systems and Population Persistence

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Publisher : American Mathematical Soc.
ISBN 13 : 082184945X
Total Pages : 426 pages
Book Rating : 4.8/5 (218 download)

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Book Synopsis Dynamical Systems and Population Persistence by : Hal L. Smith

Download or read book Dynamical Systems and Population Persistence written by Hal L. Smith and published by American Mathematical Soc.. This book was released on 2011 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a self-contained treatment of persistence theory that is accessible to graduate students, this monograph includes chapters on infinite-dimensional examples including an SI epidemic model with variable infectivity, microbial growth in a tubular bioreactor, and an age-structured model of cells growing in a chemostat.

Modeling Neural Development

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Publisher : MIT Press
ISBN 13 : 0262220660
Total Pages : 348 pages
Book Rating : 4.2/5 (622 download)

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Book Synopsis Modeling Neural Development by : Arjen Van Ooyen

Download or read book Modeling Neural Development written by Arjen Van Ooyen and published by MIT Press. This book was released on 2003 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: An important collection showing how computational and mathematical modeling can be used to study the complexities of neural development.

Introduction to Polyphasic Dispersed Systems Theory

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Publisher : Springer
ISBN 13 : 3319278533
Total Pages : 210 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Introduction to Polyphasic Dispersed Systems Theory by : Jacques Thierie

Download or read book Introduction to Polyphasic Dispersed Systems Theory written by Jacques Thierie and published by Springer. This book was released on 2015-12-30 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces a new paradigm in system description and modelling. The author shows the theoretical and practical successes of his approach, which involves replacing a traditional uniform description with a polyphasic description. This change of perspective reveals new fluxes that are cryptic in the classical description. Several case studies are given in this book, which is of interest of those working with biotechnology and green chemistry.

Structuring Biological Systems

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Publisher : CRC Press
ISBN 13 : 9780849379611
Total Pages : 296 pages
Book Rating : 4.3/5 (796 download)

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Book Synopsis Structuring Biological Systems by : S. Sitharama Iyengar

Download or read book Structuring Biological Systems written by S. Sitharama Iyengar and published by CRC Press. This book was released on 1992-04-30 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structuring Biological Systems focuses on the important components of biological systems in order to develop genetic algorithms for modeling purposes. The book considers the characteristics of biological systems from the artificial intelligence point of view, examines modeling examples of complex biological systems (such as molecular level modeling, a model of renal hemodynamics, and cognitive aspects of modeling), describes the entropy-based probability distribution for modeling of environmental and biological systems, and presents a detailed analysis of modeling cancer phenomena. Structuring Biologic Systems will benefit students and researchers interested in an interdisciplinary approach to complex problems of biological systems, as well as biologists, chemists, engineers, research physicians, and computer scientists.

Mathematical Methods for the Natural and Engineering Sciences

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Publisher : World Scientific
ISBN 13 : 9789812387509
Total Pages : 544 pages
Book Rating : 4.3/5 (875 download)

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Book Synopsis Mathematical Methods for the Natural and Engineering Sciences by : Ronald E. Mickens

Download or read book Mathematical Methods for the Natural and Engineering Sciences written by Ronald E. Mickens and published by World Scientific. This book was released on 2004 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a variety of methods required for the analysis and solution of equations which arise in the modeling of phenomena from the natural and engineering sciences. It can be used productively by both undergraduate and graduate students, as well as others who need to learn and understand these techniques. A detailed discussion is also presented for several topics that are usually not included in standard textbooks at this level: qualitative methods for differential equations, dimensionalization and scaling, elements of asymptotics, difference equations, and various perturbation methods. Each chapter contains a large number of worked examples and provides references to the appropriate literature.

Biograph

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Publisher : CUP Archive
ISBN 13 : 9780521339735
Total Pages : 260 pages
Book Rating : 4.3/5 (397 download)

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Book Synopsis Biograph by : Garrett M. Odell

Download or read book Biograph written by Garrett M. Odell and published by CUP Archive. This book was released on 1987-11-26 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Professor Segel, author of the highly acclaimed Modeling Dynamic Phenomena in Molecular and Cellular Biology, in conjunction with Professor Odell, has now produced on disc a series of programs which, together with the accompanying manual, will form an invaluable teaching and research tool, designed to integrate computer usage into a course on mathematical modelling for biologists. They will not only introduce students to the subject, but also enable them to conduct their own computer simulations. Written in the powerful programming language 'C' and able to run on IBMAT equipped with a mathematics co-processor, the programs art- designed to allow students to choose from a variety of options at each stage. No previous programming experience is required. Included in each book is a form which can be returned to obtain a free copy of the disc.

Mathematical Biophysics

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Publisher : Springer Science & Business Media
ISBN 13 : 1461487021
Total Pages : 274 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Mathematical Biophysics by : Andrew Rubin

Download or read book Mathematical Biophysics written by Andrew Rubin and published by Springer Science & Business Media. This book was released on 2013-11-26 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents concise descriptions and analysis of the classical and modern models used in mathematical biophysics. The authors ask the question "what new information can be provided by the models that cannot be obtained directly from experimental data?" Actively developing fields such as regulatory mechanisms in cells and subcellular systems and electron transport and energy transport in membranes are addressed together with more classical topics such as metabolic processes, nerve conduction and heart activity, chemical kinetics, population dynamics, and photosynthesis. The main approach is to describe biological processes using different mathematical approaches necessary to reveal characteristic features and properties of simulated systems. With the emergence of powerful mathematics software packages such as MAPLE, Mathematica, Mathcad, and MatLab, these methodologies are now accessible to a wide audience.