Mitochondria And The Future Of Medicine

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Mitochondria and the Future of Medicine

Author : Lee Know
Publisher : Chelsea Green Publishing
ISBN 13 : 1603587675
Total Pages : 274 pages
Book Rating : 4.6/5 (35 download)

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Book Synopsis Mitochondria and the Future of Medicine by : Lee Know

Download or read book Mitochondria and the Future of Medicine written by Lee Know and published by Chelsea Green Publishing. This book was released on 2018 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: With information for patients and practitioners on optimizing mitochondrial function for greater health and longevity Why do we age? Why does cancer develop? What's the connection between heart failure and Alzheimer's disease, or infertility and hearing loss? Can we extend lifespan, and if so, how? What is the Exercise Paradox? Why do antioxidant supplements sometimes do more harm than good? Many will be amazed to learn that all these questions, and many more, can be answered by a single point of discussion: mitochondria and bioenergetics. In Mitochondria and the Future of Medicine, Naturopathic Doctor Lee Know tells the epic story of mitochondria, the widely misunderstood and often-overlooked powerhouses of our cells. The legendary saga began over two billion years ago, when one bacterium entered another without being digested, which would evolve to create the first mitochondrion. Since then, for life to exist beyond single-celled bacteria, it's the mitochondria that have been responsible for this life-giving energy. By understanding how our mitochondria work, in fact, it is possible to add years to our lives, and life to our years. Current research, however, has revealed a dark side: many seemingly disconnected degenerative diseases have tangled roots in dysfunctional mitochondria. However, modern research has also endowed us with the knowledge on how to optimize its function, which is of critical importance to our health and longevity. Lee Know offers cutting-edge information on supplementation and lifestyle changes for mitochondrial optimization, such as CoQ10, D-Ribose, cannabinoids, and ketogenic dietary therapy, and how to implement their use successfully. Mitochondria and the Future of Medicine is an invaluable resource for practitioners interested in mitochondrial medicine and the true roots of chronic illness and disease, as well as anyone interested in optimizing their health.

Clinical Mitochondrial Medicine

Author : Patrick F. Chinnery
Publisher : Cambridge University Press
ISBN 13 : 0521132983
Total Pages : 229 pages
Book Rating : 4.5/5 (211 download)

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Book Synopsis Clinical Mitochondrial Medicine by : Patrick F. Chinnery

Download or read book Clinical Mitochondrial Medicine written by Patrick F. Chinnery and published by Cambridge University Press. This book was released on 2018-05-17 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: This interactive clinical textbook takes a system- and case-based approach in understanding mitochondrial disorders in clinical practice.

Life - The Epic Story of Our Mitochondria

Author : Lee Know ND
Publisher : FriesenPress
ISBN 13 : 1460251814
Total Pages : 266 pages
Book Rating : 4.4/5 (62 download)

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Book Synopsis Life - The Epic Story of Our Mitochondria by : Lee Know ND

Download or read book Life - The Epic Story of Our Mitochondria written by Lee Know ND and published by FriesenPress. This book was released on 2014-08-19 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Why do we age? Why does cancer develop? What's the connection between heart failure and Alzheimer's disease, or infertility and hearing loss? Can we extend lifespan, and if so, how? What is the Exercise Paradox? Why do antioxidant supplements sometimes do more harm than good? Many will be amazed to learn that all these questions, and many more, can be answered by a single point of discussion-mitochondria and bioenergetics. This legendary saga began over two billion years ago, when one bacterium entered another without being digested, ultimately creating the first mitochondrion. Since then, for life to exist beyond single-celled bacteria, it's the mitochondria that are responsible for this life-giving energy. Yet, current research has also revealed a dark side; many seemingly unconnected degenerative diseases have their roots in dysfunctional mitochondria. Modern research, however, has also endowed us with the knowledge on how to optimize its function, which is of critical importance to our health and longevity. By reading this book, you are about to dive into this epic story, and learn how to add years to your life, and life to your years."--Back cover.

Mitochondrial Replacement Techniques

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309388708
Total Pages : 201 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Mitochondrial Replacement Techniques by : National Academies of Sciences, Engineering, and Medicine

Download or read book Mitochondrial Replacement Techniques written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-04-17 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondrial replacement techniques (MRTs) are designed to prevent the transmission of mitochondrial DNA (mtDNA) diseases from mother to child. While MRTs, if effective, could satisfy a desire of women seeking to have a genetically related child without the risk of passing on mtDNA disease, the technique raises significant ethical and social issues. It would create offspring who have genetic material from two women, something never sanctioned in humans, and would create mitochondrial changes that could be heritable (in female offspring), and therefore passed on in perpetuity. The manipulation would be performed on eggs or embryos, would affect every cell of the resulting individual, and once carried out this genetic manipulation is not reversible. Mitochondrial Replacement Techniques considers the implications of manipulating mitochondrial content both in children born to women as a result of participating in these studies and in descendants of any female offspring. This study examines the ethical and social issues related to MRTs, outlines principles that would provide a framework and foundation for oversight of MRTs, and develops recommendations to inform the Food and Drug Administration's consideration of investigational new drug applications.

Mitochondrial Dysfunction

Author : Lawrence H. Lash
Publisher : Elsevier
ISBN 13 : 1483218619
Total Pages : 527 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Mitochondrial Dysfunction by : Lawrence H. Lash

Download or read book Mitochondrial Dysfunction written by Lawrence H. Lash and published by Elsevier. This book was released on 2013-10-22 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.

Mitochondria Diet

Author : Jeffrey Winzant
Publisher : Independently Published
ISBN 13 :
Total Pages : 56 pages
Book Rating : 4.5/5 (463 download)

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Book Synopsis Mitochondria Diet by : Jeffrey Winzant

Download or read book Mitochondria Diet written by Jeffrey Winzant and published by Independently Published. This book was released on 2021-07-30 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: Did you know that mitochondrial health is an essential key to longevity and overall well-being? Mitochondria are often overlooked in the body's complex cellular structure. They may not get as much attention as the brain or heart, but they are integral to overall health just like any other organ, and your health can be affected by the inner workings of these tiny organelles. For example, when your cells don't use energy properly from food because they cannot metabolize glucose (a type of sugar), your mitochondria cellular structures stop functioning efficiently, resulting in insulin resistance as well-both upstream triggers for health problems like cardiovascular disease, diabetes, cancer, Alzheimer's Disease, Parkinson's Disease and much more. Fortunately, there are many steps that you can take to manage these mitochondrial dysfunctions through nutrition. That's why we have outlined a 3-weeks meal plan designed with your mitochondria in mind. First things first, it's a good idea to understand what mitochondria are and why they are vital for optimal health. Stay tuned for a deep dive into what they do, why you should care about them, and how you can take better care of them through nutrition. In this guide, you'll discover: What are mitochondria Diet tips to help improve your mitochondria function Symptoms you can tell your cellular structures are not working properly A seven-day weekly plan Sample recipes to follow Imagine what changes you can see in your life if you take action today. Scroll up and click buy now to get started.

Mitochondria

Author : Douglas C. Wallace
Publisher : Cold Spring Harbor Perspective
ISBN 13 : 9781936113354
Total Pages : 0 pages
Book Rating : 4.1/5 (133 download)

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Book Synopsis Mitochondria by : Douglas C. Wallace

Download or read book Mitochondria written by Douglas C. Wallace and published by Cold Spring Harbor Perspective. This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondria are intracellular organelles that power the cell by metabolizing glucose and other energy sources to generate ATP. They are also critical in programmed cell death, and dysfunction of mitochondrial components is implicated in numerous muscle and neurodegenerative disorders, including Parkinson's disease. This volume contains contributions examining the evolution and normal function of mitochondria in cells, as well as their roles in various pathologies.

Your Mitochondria

Author : Warren L. Cargal, L. Ac.
Publisher : Acupuncture Atlanta, Inc.
ISBN 13 : 1950282562
Total Pages : 293 pages
Book Rating : 4.9/5 (52 download)

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Book Synopsis Your Mitochondria by : Warren L. Cargal, L. Ac.

Download or read book Your Mitochondria written by Warren L. Cargal, L. Ac. and published by Acupuncture Atlanta, Inc.. This book was released on 2019-07-17 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The book provides a well-researched and proven plan to increase your mitochondria's energy levels naturally to enjoy a healthy aging process." — Dr. Robyn Benson, DOM, Author, The Healthy Conscious Traveler and founder of The Self Care Revolution "This information will be invaluable for those who would like to use mitochondrial enhancement therapies to improve their general health and to extend their longevity." — Dr. Thomas N. Seyfried, Author, Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer Want to live a longer, healthier life? Want to stave off age-related diseases? Want to look younger and maintain vitality? Then you must respect your mitochondria—your key to health and longevity. The powerhouses of the cell, mitochondria take in nutrients, break them down, and create energy-rich molecules that drive cellular processors in the body. Knowing how your mitochondria work is essential to your well-being. This book takes a deep dive into the relationship between mitochondrial health, overall health, and aging. Dr. Warren Cargal, a multi-book author, board-certified Acupuncturist, and an expert on Chinese medicine with over 20 years of experience will show you: - How unhealthy mitochondria can cause cardiovascular diseases, cardiometabolic syndrome, neurodegenerative diseases, arthritis, cancer, and aging effects on the skin, eyes, and muscles. - How to take control of and increase your energy reserves to make them efficient. - How to restore your mitochondria so you can combat increased body fat and reduced lean muscle mass, inefficient metabolism, increased low-grade inflammation, inadequate performance, accelerating aging, and, unfortunately for some, premature death. Your Mitochondria: Key to Health and Longevity is a must-read for anyone who wants to live an abundant and healthy life.

Mitochondrial Dysfunction: A Functional Medicine Approach to Diagnosis and Treatment: Get Rid of Fat, Fatigue, and Brain Fog

Author : Michael T. Chang
Publisher :
ISBN 13 : 9781733397315
Total Pages : 194 pages
Book Rating : 4.3/5 (973 download)

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Book Synopsis Mitochondrial Dysfunction: A Functional Medicine Approach to Diagnosis and Treatment: Get Rid of Fat, Fatigue, and Brain Fog by : Michael T. Chang

Download or read book Mitochondrial Dysfunction: A Functional Medicine Approach to Diagnosis and Treatment: Get Rid of Fat, Fatigue, and Brain Fog written by Michael T. Chang and published by . This book was released on 2019-09-08 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Are of sick and tired of being tired, overweight, brain fogged and depressed? You have tried everything and nothing makes a difference. The answer may lie deep inside your cells called the mitochondria, the energy factories that power the cell. By rebooting them in a proven treatment method, you can not only get rid of your symptoms but also prevent chronic degenerative diseases like cancer and Alzheimer's and even slow the aging process. Functional medicine can help you diagnose and treat mitochondrial dysfunction.Dr. Michael Chang, MD, CFMP, Board certified in Pathology and Laboratory Medicine, draws from his experience at Healed and Whole Clinic using a validated treatment approach to this condition. He has also personally experienced mitochondrial fatigue stemming from biomechanical leg pain from which he has now recovered by applying the same treatments as outlined in this book.

Mitochondria in Health and Diseases

Author : Sabzali Javadov
Publisher :
ISBN 13 : 9783039363841
Total Pages : 434 pages
Book Rating : 4.3/5 (638 download)

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Book Synopsis Mitochondria in Health and Diseases by : Sabzali Javadov

Download or read book Mitochondria in Health and Diseases written by Sabzali Javadov and published by . This book was released on 2020-09-04 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondria are subcellular organelles evolved by the endosymbiosis of bacteria with eukaryotic cells. They are the main source of ATP in the cell and engaged in other aspects of cell metabolism and cell function, including the regulation of ion homeostasis, cell growth, redox status, and cell signaling. Due to their central role in cell life and death, mitochondria are also involved in the pathogenesis and progression of human diseases/conditions, including neurodegenerative and cardiovascular disorders, cancer, diabetes, inflammation, and aging. However, despite the increasing number of studies, precise mechanisms whereby mitochondria are involved in the regulation of basic physiological functions, as well as their role in the cell under pathophysiological conditions, remain unknown. A lack of in-depth knowledge of the regulatory mechanisms of mitochondrial metabolism and function, as well as interplay between the factors that transform the organelle from its role in pro-survival to pro-death, have hindered the development of new mitochondria-targeted pharmacological and conditional approaches for the treatment of human diseases. This book highlights the latest achievements in elucidating the role of mitochondria under physiological conditions, in various cell/animal models of human diseases, and in patients.

Mitochondrial Function In Vivo Evaluated by NADH Fluorescence

Author : Avraham Mayevsky
Publisher : Springer
ISBN 13 : 3319166824
Total Pages : 285 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Mitochondrial Function In Vivo Evaluated by NADH Fluorescence by : Avraham Mayevsky

Download or read book Mitochondrial Function In Vivo Evaluated by NADH Fluorescence written by Avraham Mayevsky and published by Springer. This book was released on 2015-06-20 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers both the technological development and biomedical applications of NADH fluorescence. Topics covered include perspectives on the history of monitoring NADH fluorescence, the relationship between mitochondrial function and other functions at the tissue level, responses of NADH to physiological and pathophysiological conditions, monitoring of NADH in the human brain and other organs, and metabolism. It also includes an in-depth look at flavoprotein (Fp) fluorescence and NADH in relation to redox state. This is an ideal book for biomedical engineers, researchers, and graduate students interested in learning the biomedical applications of NADH fluorescence. This book also: Covers multisite monitoring of NADH, as well as multiparametric responses of NADH to physiological and pathophysiological conditions, and monitoring of various organs in various animal models Describes the relationship between brain activation (i.e. epileptic activity and cortical spreading depression) and NADH redox state Presents the effects of hypoxia,hyperbaric hyperoxia, and ischemia on brain NADH fluorescence and other tissue physiological parameters About the Author Avraham Mayevsky, Ph.D. is a Professor Emeritus in theFaculty of Life Sciences and the Brain Research Center at Bar Ilan University, Israel. He has published more than two hundred papers in the field of mitochondrial function and tissue physiology in vivo under pathophysiological conditions.

Organelle Contact Sites

Author : Mitsuo Tagaya
Publisher : Springer
ISBN 13 : 9811045674
Total Pages : 254 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Organelle Contact Sites by : Mitsuo Tagaya

Download or read book Organelle Contact Sites written by Mitsuo Tagaya and published by Springer. This book was released on 2017-08-16 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the first comprehensive coverage of the quickly evolving research field of membrane contact sites (MCS). A total of 16 chapters explain their organization and role and unveil the significance of MCS for various diseases. MCS, the intracellular structures where organellar membranes come in close contact with one another, mediate the exchange of proteins, lipids, and ions. Via these functions, MCS are critical for the survival and the growth of the cell. Owing to that central role in the functioning of cells, MCS dysfunctions lead to important defects of human physiology, influence viral and bacterial infection, and cause disease such as inflammation, type II diabetes, neurodegenerative disorders, and cancer. To approach such a multifaceted topic, this volume assembles a series of chapters dealing with the full array of research about MCS and their respective roles for diseases. Most chapters also introduce the history and the state of the art of MCS research, which will initiate discussion points for the respective types of MCS for years to come. This work will appeal to all cell biologists as well as researchers on diseases that are impacted by MCS dysfunction. Additionally, it will stimulate graduate students and postdocs who will energize, drive, and develop the research field in the near future.

Plant Mitochondria

Author : Olivier Van Aken
Publisher : Humana
ISBN 13 : 9781071616529
Total Pages : 342 pages
Book Rating : 4.6/5 (165 download)

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Book Synopsis Plant Mitochondria by : Olivier Van Aken

Download or read book Plant Mitochondria written by Olivier Van Aken and published by Humana. This book was released on 2021-10-15 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume presents a wide range of techniques for plant mitochondrial analysis, ranging from tried-and-tested work horse techniques to the latest innovations. Within its pages, it explores subjects such as affinity-based isolation of mitochondria with magnetic beads, mitochondrial quality assessment protocols, measurement of uptake and release of specific metabolites, mitochondrial protein identification and visualization, as well as gene splicing and editing, and much more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Plant Mitochondria: Methods and Protocols provides a highly useful set of methodologies for the plant mitochondrial community to help discover more interesting aspects of plant mitochondria in the years to come.

Sarcopenia

Author : Alfonso J. Cruz-Jentoft
Publisher : John Wiley & Sons
ISBN 13 : 1119597900
Total Pages : 464 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Sarcopenia by : Alfonso J. Cruz-Jentoft

Download or read book Sarcopenia written by Alfonso J. Cruz-Jentoft and published by John Wiley & Sons. This book was released on 2021-06-15 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: SARCOPENIA An in-depth examination of sarcopenia’s underexplored yet widespread impact within the field of gerontology Sarcopenia is common in older men and women, and yet awareness of its clinical relevance is still relatively low. Only formally included in the International Classification of Diseases in 2016, the condition may impact societies with serious health-related and financial consequences unless consistent, effective methods of identification and management are adopted. This second edition of Sarcopenia provides geriatricians and other healthcare professionals with a revised and expanded examination of this understudied and underdiagnosed condition. Edited by two leading authorities on the subject, it covers the epidemiology and diagnosis of sarcopenia, as well as treatment options and possible prevention strategies. Eight newly written chapters build upon existing knowledge with fresh data on topics including sarcopenia’s biomarkers and its impact on the healthcare economy. This important text: Defines sarcopenia and explains its clinical relevance Covers all recent scientific evidence Outlines treatment options Considers prevention strategies Discusses sarcopenia as a public health priority Features eight new chapters covering topics such as sarcopenia’s clinical management, its biomarkers, and its financial impact Containing vital information for clinicians and other professionals working in geriatric care, nursing homes, nutrition, cancer, endocrinology, surgery, sports medicine and many other specialties, Sarcopenia, second edition, is a groundbreaking and essential new resource.

Understanding the Process of Aging

Author : Lester Packer
Publisher : CRC Press
ISBN 13 : 9780824717230
Total Pages : 388 pages
Book Rating : 4.7/5 (172 download)

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Book Synopsis Understanding the Process of Aging by : Lester Packer

Download or read book Understanding the Process of Aging written by Lester Packer and published by CRC Press. This book was released on 1999-01-12 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: This innovative reference explores a wide selection of topics associated with aging, providing a solid understanding of the significance and molecular basis of the aging process and charting the course of future research in the area. Stresses the interplay of mitochondria, mitochondrial DNA, oxidants, and antioxidants! Featuring the research of over 55 experts in the area, Understanding the Process of Aging covers the functions of nitric oxide and peroxynitrite in mitochondria integrates several views on the role of mitochondria in the development of apoptosis gives a quantitative analysis of mutations of mitochondrial DNA during human aging highlights mitochondrial free radical production introduces new roles of ubiquinone in mitochondrial functions offers new antioxidant-based complementary therapeutic strategies details aspects of intact cells and whole organisms in health and disease and more! Featuring over 1800 references, tables, drawings, and photographs, Understanding the Process of Aging benefits nutritionists and dieticians, geriatricians, cell and molecular biologists, chemists and biochemists, pharmacologists, biotechnologists, neurologists, cardiologists, oncologists, dermatologists, and graduate and medical school students in these disciplines.

Diagnosis and Treatment of Chronic Fatigue Syndrome and Myalgic Encephalitis

Author : Sarah Myhill
Publisher : Chelsea Green Publishing
ISBN 13 : 160358787X
Total Pages : 434 pages
Book Rating : 4.6/5 (35 download)

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Book Synopsis Diagnosis and Treatment of Chronic Fatigue Syndrome and Myalgic Encephalitis by : Sarah Myhill

Download or read book Diagnosis and Treatment of Chronic Fatigue Syndrome and Myalgic Encephalitis written by Sarah Myhill and published by Chelsea Green Publishing. This book was released on 2018 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Original edition published in 2017 by Hammersmith Books, London, United Kingdom"--T.p. verso.

Goodman's Medical Cell Biology

Author : Steven R. Goodman
Publisher : Academic Press
ISBN 13 : 0128179287
Total Pages : 444 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Goodman's Medical Cell Biology by : Steven R. Goodman

Download or read book Goodman's Medical Cell Biology written by Steven R. Goodman and published by Academic Press. This book was released on 2020-06-11 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Goodman's Medical Cell Biology, Fourth Edition, has been student tested and approved for decades. This updated edition of this essential textbook provides a concise focus on eukaryotic cell biology (with a discussion of the microbiome) as it relates to human and animal disease. This is accomplished by explaining general cell biology principles in the context of organ systems and disease.This new edition is richly illustrated in full color with both descriptive schematic diagrams and laboratory findings obtained in clinical studies. This is a classic reference for moving forward into advanced study. - Includes five new chapters: Mitochondria and Disease, The Cell Biology of the Immune System, Stem Cells and Regenerative Medicine, Omics, Informatics, and Personalized Medicine, and The Microbiome and Disease - Contains over 150 new illustrations, along with revised and updated illustrations - Maintains the same vision as the prior editions, teaching cell biology in a medically relevant manner in a concise, focused textbook