MicroRNAs in malignant tumors of the skin

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Author :
Publisher : Springer
ISBN 13 : 3658127945
Total Pages : 251 pages
Book Rating : 4.6/5 (581 download)

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Book Synopsis MicroRNAs in malignant tumors of the skin by : Michael Sand

Download or read book MicroRNAs in malignant tumors of the skin written by Michael Sand and published by Springer. This book was released on 2016-05-30 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Michael Sand gives the reader an overview of current techniques in expression profiling of miRNAs and their maturation machinery in the skin. This book is a postdoctoral thesis on miRNAs in cutaneous malignant melanoma and non-melanoma skin cancer with a focus on the miRNA processing machinery and miRNA expression profiling. The research presented in this book was performed in the Dermatologic Surgery Section at the Department of Dermatology, Venereology and Allergology of the Ruhr-University Bochum, Germany and gives the reader an overview of current techniques in expression profiling of miRNAs and their maturation machinery in the skin.

MicroRNA Cancer Regulation

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Publisher : Springer Science & Business Media
ISBN 13 : 9400755902
Total Pages : 352 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis MicroRNA Cancer Regulation by : Ulf Schmitz

Download or read book MicroRNA Cancer Regulation written by Ulf Schmitz and published by Springer Science & Business Media. This book was released on 2013-02-03 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited reflects the current state of knowledge about the role of microRNAs in the formation and progression of solid tumours. The main focus lies on computational methods and applications, together with cutting edge experimental techniques that are used to approach all aspects of microRNA regulation in cancer. We are sure that the emergence of high-throughput quantitative techniques will make this integrative approach absolutely necessary in the near future. This book will be a resource for researchers starting out with cancer microRNA research, but is also intended for the experienced researcher who wants to incorporate concepts and tools from systems biology and bioinformatics into his work. Bioinformaticians and modellers are provided with a general perspective on microRNA biology in cancer, and the state-of-the-art in computational microRNA biology.

Histological Diagnosis of Nevi and Melanoma

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Publisher : Springer Science & Business Media
ISBN 13 : 3642373119
Total Pages : 764 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Histological Diagnosis of Nevi and Melanoma by : Guido Massi

Download or read book Histological Diagnosis of Nevi and Melanoma written by Guido Massi and published by Springer Science & Business Media. This book was released on 2013-09-16 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt: The interpretation of melanocytic tumors represents probably the most difficult task in the field of dermatopathology. The second edition of this text and atlas depicts a broad range of the most important and most challenging melanocytic lesions. Each individual case is illustrated with at least three high-quality color photographs and is commented on at length, highlighting the diagnostic clues. The goal of the authors is to assist the ordinary pathologist in making a precise workable diagnosis in their daily practice. They achieve this by providing simple criteria that will serve as a sound basis for an unequivocal diagnosis of either a benign or a malignant melanocytic neoplasm. The reader will find Histological Diagnosis of Nevi and Melanoma to be an invaluable guide to correct diagnosis even in difficult or rare cases.

Handbook of Nutrition, Diet, and Epigenetics

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Publisher : Springer
ISBN 13 : 9783319555294
Total Pages : 0 pages
Book Rating : 4.5/5 (552 download)

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Book Synopsis Handbook of Nutrition, Diet, and Epigenetics by : Vinood B. Patel

Download or read book Handbook of Nutrition, Diet, and Epigenetics written by Vinood B. Patel and published by Springer. This book was released on 2019-02-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This multivolume reference work addresses the fact that the well being of humankind is predicated not only on individuals receiving adequate nutrition but also on their genetic makeup. The work includes more than 100 chapters organized in the following major sections: Introduction and Overview; Epigenetics of Organs and Diseases in Relation to Diet and Nutrition; Detailed Processes in Epigenetics of Diet and Nutrition; Modulating Epigenetics with Diet and Nutrition; and Practical Techniques. While it is well known that genes may encode proteins responsible for structural and dynamic components, there is an increasing body of evidence to suggest that nutrition itself may alter the way in which genes are expressed via the process of epigenetics. This is where chemically imposed alteration in the DNA sequence occurs or where the functional expression of DNA is modulated. This may include changes in DNA methylation, non-coding RNA, chromatin, histone acetylation or methylation, and genomic imprinting. Knowledge regarding the number of dietary components that impact on epigenetic processes is increasing almost daily. Marshalling all the information on the complex relationships between diet, nutrition, and epigenetic processes is somewhat difficult due to the wide myriad of material. It is for this reason that the present work has been compiled.

Textbook of Aging Skin

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Publisher : Springer Science & Business Media
ISBN 13 : 3540896554
Total Pages : 1255 pages
Book Rating : 4.5/5 (48 download)

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Book Synopsis Textbook of Aging Skin by : Miranda A. Farage

Download or read book Textbook of Aging Skin written by Miranda A. Farage and published by Springer Science & Business Media. This book was released on 2009-12-02 with total page 1255 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive ‘Major Reference Book’ compiles all current and latest information on aging skin in a two-volume set. Highly structured with a reader-friendly format, it covers a wide range of areas such as basic sciences, the different diseases and conditions which occur with aging (from malignant to non-malignant), the latest techniques and methods being used such as bioengineering methods and biometrics as well as toxicological and safety considerations for the elderly population. It also illustrates the global consumers’ sociological and psychological implications, ethnicity and gender differences and includes marketing considerations for this elderly group. This unique and comprehensive guide will become the main reference textbook on this topic.

MicroRNAs

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Publisher : Cambridge University Press
ISBN 13 : 9780521118552
Total Pages : 580 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis MicroRNAs by : Krishnarao Appasani

Download or read book MicroRNAs written by Krishnarao Appasani and published by Cambridge University Press. This book was released on 2009-08-20 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: MicroRNAs (miRNAs) are RNA molecules, conserved by evolution, that regulate gene expressions and their recent discovery is revolutionising both basic biomedical research and drug discovery. Expression levels of MiRNAs have been found to vary between tissues and with developmental stages and hence evaluation of the global expression of miRNAs potentially provides opportunities to identify regulatory points for many different biological processes. This wide-ranging reference work, written by leading experts from both academia and industry, will be an invaluable resource for all those wishing to use miRNA techniques in their own research, from graduate students, post-docs and researchers in academia to those working in R&D in biotechnology and pharmaceutical companies who need to understand this emerging technology. From the discovery of miRNAs and their functions to their detection and role in disease biology, this volume uniquely integrates the basic science with industry application towards drug validation, diagnostic and therapeutic development. Forewords by: Sidney Altman, Yale University, Winner of the Nobel Prize in Chemistry, 1989 and Victor R. Ambros, Dartmouth Medical School, Co-discoverer of MicroRNAs

MicroRNA in Solid Tumor and Hematological Diseases

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Publisher :
ISBN 13 : 9783036530895
Total Pages : 226 pages
Book Rating : 4.5/5 (38 download)

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Book Synopsis MicroRNA in Solid Tumor and Hematological Diseases by : Francesca Lovat

Download or read book MicroRNA in Solid Tumor and Hematological Diseases written by Francesca Lovat and published by . This book was released on 2022 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: MicroRNAs (miRNAs), which are a type of short non-coding RNA, are involved in number of processes, such as differentiation, development, inflammation, immune response, and cancer. miRNAs, which act as oncogenes or tumor suppressor genes, can control and regulate the translation and stability of target messenger RNA, contributing to cancer pathogenesis. Despite the progress that has been made in discovering the mechanisms of how miRNAs function in tumors, many questions and aspects of miRNA biology and processing still remain to be determined. This Special Issue, titled “MicroRNA in Solid Tumor and Hematological Diseases”, provides a panorama of the existing knowledge gaps and potential uses of microRNAs to predict clinical outcome or response to therapies and provides evidence to explain their role as biomarkers to modulate the biological pathways that are critical for cancer development and progression. It includes eleven peer-reviewed papers that cover the role of microRNAs in different tumor types and their potential applications in diagnosis and clinical approaches.

Cutaneous Melanoma

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Publisher : Springer
ISBN 13 : 9783030050689
Total Pages : 0 pages
Book Rating : 4.0/5 (56 download)

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Book Synopsis Cutaneous Melanoma by : Charles M. Balch

Download or read book Cutaneous Melanoma written by Charles M. Balch and published by Springer. This book was released on 2020-01-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the leading melanoma experts from the United States, Australia, and Europe, this new edition incorporates the clinical outcomes of more than 70,000 patients treated at major melanoma centers throughout the world and is the definitive and most authoritative textbook on melanoma used worldwide. Providing the most up-to-date and comprehensive information needed for the clinical management and scientific study of melanoma, Cutaneous Melanoma, 6th edition covers everything from precursors of melanoma to advanced stages of metastatic disease.

MicroRNAs in Cancer

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Publisher : CRC Press
ISBN 13 : 1466576774
Total Pages : 426 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis MicroRNAs in Cancer by : Cesar Lopez-Camarillo

Download or read book MicroRNAs in Cancer written by Cesar Lopez-Camarillo and published by CRC Press. This book was released on 2013-02-22 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: MicroRNA (miRNA) biology is a cutting-edge topic in basic as well as biomedical research. This is a specialized book focusing on the current understanding of the role of miRNAs in the development, progression, invasion, and metastasis of diverse types of cancer. It also reviews their potential for applications in cancer diagnosis, prognosis, and th

The Drosophila Model in Cancer

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Publisher : Springer Nature
ISBN 13 : 3030236293
Total Pages : 251 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis The Drosophila Model in Cancer by : Wu-Min Deng

Download or read book The Drosophila Model in Cancer written by Wu-Min Deng and published by Springer Nature. This book was released on 2019-09-13 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a series of review articles that capture the advances in using the fruit fly, Drosophila melanogaster, model system to address a wide range of cancer-related topics. Articles in this book provide case studies that shed light on the intricate cellular and molecular mechanisms underlying tumor formation and progression. Readers will discover the beauty of the fly model’s genetic simplicity and the vast arsenal of powerful genetic tools enabling its efficient and adaptable use. This model organism has provided a unique opportunity to address questions regarding cancer initiation and development that would be extremely challenging in other model systems. This book provides a useful resource for a researcher who wishes to learn about and apply the Drosophila model to tackle fundamental questions in cancer biology, and to find new ways to fight against this devastating disease.

Vasculogenic Mimicry

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Publisher : Springer Nature
ISBN 13 : 1071624032
Total Pages : 180 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Vasculogenic Mimicry by : Emily Marques dos Reis

Download or read book Vasculogenic Mimicry written by Emily Marques dos Reis and published by Springer Nature. This book was released on 2022-06-30 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides detailed protocols for the identification and understanding of vasculogenic mimicry process in vitro and in vivo, in addition to protocols for microscopy and histology. Chapters guide readers through different materials, commercial and homemade scaffolds, Matrigel, cancer spheroids, 3D tissue constructs, vasculogenic processes, and mathematical model building. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Vasculogenic Mimicry: Methods and Protocols aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.

MicroRNA in Cancer

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Publisher : Springer Science & Business Media
ISBN 13 : 9400746555
Total Pages : 149 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis MicroRNA in Cancer by : Suresh Alahari

Download or read book MicroRNA in Cancer written by Suresh Alahari and published by Springer Science & Business Media. This book was released on 2012-08-01 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of microRNA biology is really emerging in the last couple of years. Several investigators highlighted the importance of miRNAs in cancer. Although there is so much literature on microRNAs exist, a comprehensive book is still not available. Thus this book will be a great use to the scientists in the field of cancer biology. In addition, this book will be a good source of information for undergraduate, graduate students who want to develop their research careers in cancer biology.

Oncogene and Cancer

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Publisher : Inst za onkologiju i radiol
ISBN 13 : 9535108581
Total Pages : 497 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Oncogene and Cancer by : Yahwardiah Siregar

Download or read book Oncogene and Cancer written by Yahwardiah Siregar and published by Inst za onkologiju i radiol. This book was released on 2013-01-24 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes a course of cancer growth starting from normal cells to cancerous form and the genomic instability, the cancer treatment as well as its prevention in form of the invention of a vaccine. Some diseases are also discussed in detail, such as breast cancer, leucaemia, cervical cancer, and glioma. Understanding cancer through its molecular mechanism is needed to reduce the cancer incidence. How to treat cancer more effectively and the problems like drug resistance and metastasis are very clearly illustrated in this publication as well as some research result that could be used to treat the cancer patients in the very near future. The book was divided into six main sections: 1. HER2 Carcinogenesis: Etiology, Treatment and Prevention; 2. DNA Repair Mechanism and Cancer; 3. New Approach to Cancer Mechanism; 4. New Role of Oncogenes and Tumor Suppressor Genes; 5. Non Coding RNA and Micro RNA in Tumorigenesis; 6. Oncogenes for Transcription Factors

Human Skin Cancers

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Publisher : BoD – Books on Demand
ISBN 13 : 1789230942
Total Pages : 214 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Human Skin Cancers by : Miroslav Blumenberg

Download or read book Human Skin Cancers written by Miroslav Blumenberg and published by BoD – Books on Demand. This book was released on 2018-05-02 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human skin cancers, the most common type of tumors, represent a significant health burden. The deadliest is unquestionably melanoma. Half of melanomas have an activating mutation in the BRAF gene, prompting development of novel drugs, vemurafenib and dabrafenib, specifically targeting mutated BRAF. Trametinib and cobimetinib, which block MEK, a BRAF effector protein, have been used in combination with BRAF inhibitors. A promising new melanoma treatment is immunotherapy, approach that boosts patient's own immune system to attack cancer. Pembrolizumab and nivolumab inhibit PD-1, whereas Ipilimumab targets CTLA-4, another immunity check point, to boost the immune response. Here we focus on pathways, mechanisms, targets and treatments of human skin cancers, with particular emphasis on the new developments in the research on melanomas.

Arsenic

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Publisher : John Wiley & Sons
ISBN 13 : 111851114X
Total Pages : 584 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis Arsenic by : J. Christopher States

Download or read book Arsenic written by J. Christopher States and published by John Wiley & Sons. This book was released on 2015-11-02 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates the chemistry, toxicology, and health effects of arsenic using novel modeling techniques, case studies, experimental data, and future perspectives. • Covers exposure sources, health risks, and mechanisms of one of the most toxic minerals in the world • Helps readers understand potential health effects of arsenic, using population studies, mammalian and invertebrate models, and pharmacokinetic and toxicokinetic models • Discusses outcomes, epidemiology, real-life examples, and modes of action for arsenic-induced diseases, like lung cancer, diabetes, cardiovascular and pulmonary diseases, and immunotoxicity • Acts as a reference for toxicologists, environmental chemists, and risk assessors and includes up-to-date, novel modeling techniques for scientists • Includes future perspectives on special topics, like extrapolation from experimental models to human exposures, biomarkers for phenotypic anchoring, and pathology of chronic exposure

Current Advances on Non-Melanoma Skin Cancer

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Author :
Publisher : MDPI
ISBN 13 : 3036508902
Total Pages : 124 pages
Book Rating : 4.0/5 (365 download)

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Book Synopsis Current Advances on Non-Melanoma Skin Cancer by : Constantin Caruntu

Download or read book Current Advances on Non-Melanoma Skin Cancer written by Constantin Caruntu and published by MDPI. This book was released on 2021-09-02 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book is devoted to the design, application and characterization of thin films and structures, with special emphasis on optical applications. It comprises ten papers—five featured and five regular—authored by scientists all over the world. Diverse materials are studied and their possible applications are demonstrated and discussed—transparent conductive coatings and structures from ZnO doped with Al and Ga and Ti-doped SnO2, polymers and nanosized zeolite thin films for optical sensing, TiO2 with linear and nonlinear optical properties, organic diamagnetic materials, broadband optical coatings, CrWN glass molding coatings, and silicon on insulator waveguides.

Cell Cycle Regulation

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Author :
Publisher : Results and Problems in Cell Differentiation
ISBN 13 :
Total Pages : 400 pages
Book Rating : 4.X/5 (3 download)

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Book Synopsis Cell Cycle Regulation by : Philipp Kaldis

Download or read book Cell Cycle Regulation written by Philipp Kaldis and published by Results and Problems in Cell Differentiation. This book was released on 2006-06-26 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a state-of-the-art summary of the latest achievements in cell cycle control research with an outlook on the effect of these findings on cancer research. The chapters are written by internationally leading experts in the field. They provide an updated view on how the cell cycle is regulated in vivo, and about the involvement of cell cycle regulators in cancer.