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Microrheology
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Download or read book Microrheology written by Eric M. Furst and published by Oxford University Press. This book was released on 2017 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rheology is the study of the flow of matter. It is an important and active field of research that spans numerous disciplines and technological applications. The aim of this work is to provide an introduction to the theory and practice of microrheology, a relatively new area of rheology.
Book Synopsis Microrheology with Optical Tweezers by : Manlio Tassieri
Download or read book Microrheology with Optical Tweezers written by Manlio Tassieri and published by CRC Press. This book was released on 2016-10-14 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thanks to the pioneering works of Ashkin and coworkers, optical tweezers (OTs) have become an invaluable tool for myriad studies throughout the natural sciences. Their success relies on the fact that they can be considered as exceptionally sensitive transducers that are able to resolve pN forces and nm displacements, with high temporal resolution, down to μs. Hence their application to study a wide range of biological phenomena such as measuring the compliance of bacterial tails, the forces exerted by a single motor protein, and the mechanical properties of human red blood cells and of individual biological molecules. The number of articles related to them totals to a whopping 58,000 (source Google Scholar)! Microrheology is a branch of rheology, but it works at micrometer length scales and with microliter sample volumes. Therefore, microrheology techniques have been revealed to be very useful tools for all those rheological/mechanical studies where rare or precious materials are employed, such as in biological and biomedical studies. The aim of this book is to provide a pedagogical introduction to the physics principles governing both the optical tweezers and their application in the field of microrheology of complex materials. This is achieved by following a linear path that starts from a narrative introduction of the "nature of light," followed by a rigorous description of the fundamental equations governing the propagation of light through matter. Moreover, some of the many possible instrumental configurations are presented, especially those that better adapt to perform microrheology measurements. In order to better appreciate the microrheological methods with optical tweezers explored in this book, informative introductions to the basic concepts of linear rheology, statistical mechanics, and the most popular microrheology techniques are also given. Furthermore, an enlightening prologue to the general applications of optical tweezers different from rheological purposes is provided at the end of the book.
Book Synopsis Microrheology with Optical Tweezers by : Manlio Tassieri
Download or read book Microrheology with Optical Tweezers written by Manlio Tassieri and published by CRC Press. This book was released on 2016-10-14 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thanks to the pioneering works of Ashkin and coworkers, optical tweezers (OTs) have become an invaluable tool for myriad studies throughout the natural sciences. Their success relies on the fact that they can be considered as exceptionally sensitive transducers that are able to resolve pN forces and nm displacements, with high temporal resolution, down to μs. Hence their application to study a wide range of biological phenomena such as measuring the compliance of bacterial tails, the forces exerted by a single motor protein, and the mechanical properties of human red blood cells and of individual biological molecules. The number of articles related to them totals to a whopping 58,000 (source Google Scholar)! Microrheology is a branch of rheology, but it works at micrometer length scales and with microliter sample volumes. Therefore, microrheology techniques have been revealed to be very useful tools for all those rheological/mechanical studies where rare or precious materials are employed, such as in biological and biomedical studies. The aim of this book is to provide a pedagogical introduction to the physics principles governing both the optical tweezers and their application in the field of microrheology of complex materials. This is achieved by following a linear path that starts from a narrative introduction of the "nature of light," followed by a rigorous description of the fundamental equations governing the propagation of light through matter. Moreover, some of the many possible instrumental configurations are presented, especially those that better adapt to perform microrheology measurements. In order to better appreciate the microrheological methods with optical tweezers explored in this book, informative introductions to the basic concepts of linear rheology, statistical mechanics, and the most popular microrheology techniques are also given. Furthermore, an enlightening prologue to the general applications of optical tweezers different from rheological purposes is provided at the end of the book.
Book Synopsis Microscale Diagnostic Techniques by : Kenny Breuer
Download or read book Microscale Diagnostic Techniques written by Kenny Breuer and published by Springer Science & Business Media. This book was released on 2005-12-06 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microscale Diagnostic Techniques highlights the most innovative and powerful developments in microscale diagnostics. It provides a resource for scientists and researchers interested in learning about the techniques themselves, including their capabilities and limitations. The fields of Micro- and Nanotechnology have emerged over the past decade as a major focus of modern scientific and engineering research and technology. Driven by advances in microfabrication, the investigation, manipulation and engineering of systems characterized by micrometer and, more recently, nanometer scales have become commonplace throughout all technical disciplines. With these developments, an entirely new collection of experimental techniques has been developed to explore and characterize such systems.
Download or read book Cell Mechanics written by Yu-Li Wang and published by Academic Press. This book was released on 2007-07-05 with total page 629 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell mechanics is the field of study that looks at how cells detect, modify, and respond to the physical properties of the cell environment. Cells communicate with each other through chemical and physical signals which are involved in a range of process from embryogenesis and wound healing to pathological conditions such as cancerous invasion. Similar principles are also likely to be critical for success in regenerative medicine. Cell mechanics is thus central to understanding these principles. As cell mechanics draws from the fields of biology, chemistry, physics, engineering, and mathematics, this book aims not only to provide a collection of research methods, but also to develop a common language among scientists who share the interest in cell mechanics but enter the field with diverse backgrounds. To this end all of the contributing authors have sought to explain in plain language the nature of the biological problems, the rationale for the approaches, in addition to the methods themselves. In addition, to balance practical utility against conceptual advances, Cell Mechanics has intentionally included both chapters that provide detailed recipes and those that emphasize basic principles. - Presents a distinctive emphasis on matrix mechanics and their interplay with cell functions - Includes highly significant topics relevant to basic and translational research, as well as tissue engineering - Emphasizes mechanical input and output of cells
Book Synopsis Complex Fluids in Biological Systems by : Saverio E. Spagnolie
Download or read book Complex Fluids in Biological Systems written by Saverio E. Spagnolie and published by Springer. This book was released on 2014-11-27 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as an introduction to the continuum mechanics and mathematical modeling of complex fluids in living systems. The form and function of living systems are intimately tied to the nature of surrounding fluid environments, which commonly exhibit nonlinear and history dependent responses to forces and displacements. With ever-increasing capabilities in the visualization and manipulation of biological systems, research on the fundamental phenomena, models, measurements, and analysis of complex fluids has taken a number of exciting directions. In this book, many of the world’s foremost experts explore key topics such as: Macro- and micro-rheological techniques for measuring the material properties of complex biofluids and the subtleties of data interpretation Experimental observations and rheology of complex biological materials, including mucus, cell membranes, the cytoskeleton, and blood The motility of microorganisms in complex fluids and the dynamics of active suspensions Challenges and solutions in the numerical simulation of biologically relevant complex fluid flows This volume will be accessible to advanced undergraduate and beginning graduate students in engineering, mathematics, biology, and the physical sciences, but will appeal to anyone interested in the intricate and beautiful nature of complex fluids in the context of living systems.
Book Synopsis Proteins in Solution and at Interfaces by : Juan M. Ruso
Download or read book Proteins in Solution and at Interfaces written by Juan M. Ruso and published by John Wiley & Sons. This book was released on 2013-01-31 with total page 823 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explores new applications emerging from our latest understanding of proteins in solution and at interfaces Proteins in solution and at interfaces increasingly serve as the starting point for exciting new applications, from biomimetic materials to nanoparticle patterning. This book surveys the state of the science in the field, offering investigators a current understanding of the characteristics of proteins in solution and at interfaces as well as the techniques used to study these characteristics. Moreover, the authors explore many of the new and emerging applications that have resulted from the most recent studies. Topics include protein and protein aggregate structure; computational and experimental techniques to study protein structure, aggregation, and adsorption; proteins in non-standard conditions; and applications in biotechnology. Proteins in Solution and at Interfaces is divided into two parts: Part One introduces concepts as well as theoretical and experimental techniques that are used to study protein systems, including X-ray crystallography, nuclear magnetic resonance, small angle scattering, and spectroscopic methods Part Two examines current and emerging applications, including nanomaterials, natural fibrous proteins, and biomolecular thermodynamics The book's twenty-three chapters have been contributed by leading experts in the field. These contributions are based on a thorough review of the latest peer-reviewed findings as well as the authors' own research experience. Chapters begin with a discussion of core concepts and then gradually build in complexity, concluding with a forecast of future developments. Readers will not only gain a current understanding of proteins in solution and at interfaces, but also will discover how theoretical and technical developments in the field can be translated into new applications in material design, genetic engineering, personalized medicine, drug delivery, biosensors, and biotechnology.
Book Synopsis Handbook of Imaging in Biological Mechanics by : Corey P. Neu
Download or read book Handbook of Imaging in Biological Mechanics written by Corey P. Neu and published by CRC Press. This book was released on 2014-10-24 with total page 579 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emerging imaging techniques have opened new fronts to investigate tissues, cells, and proteins. Transformative technologies such as microCT scans, super-resolution microscopy, fluorescence-based tools, and other methods now allow us to study the mechanics of cancer, dissect the origins of cellular force regulation, and examine biological specimens
Book Synopsis Intermediate Filament Mechanics Across Scales – From Single Filaments to Single Interactions and Networks in Cells by : Anna Veronika Schepers
Download or read book Intermediate Filament Mechanics Across Scales – From Single Filaments to Single Interactions and Networks in Cells written by Anna Veronika Schepers and published by Universitätsverlag Göttingen. This book was released on 2022 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mechanical properties of cells are largely determined by the cytoskeleton. The cytoskeleton is an intricate and complex structure formed by protein filaments, motor proteins, and crosslinkers. The three main types of protein filaments are microtubules, actin filaments, and intermediate filaments ( IFs ). Whereas the proteins that form microtubules and actin filaments are exceptionally conserved throughout cell types and organisms, the family of IFs is diverse. For example, the IF protein vimentin is expressed in relatively motile fibroblasts, and keratin IFs are found in epithelial cells. This variety of IF proteins might therefore be linked to the various mechanical properties of different cell types. In the scope of this thesis, I combine studies of IF mechanics on different time scales and in systems of increasing complexity, from single filaments to networks in cells. This multiscale approach allows for the simplification necessary to interpret observations while adding increasing physiological context in subsequent experiments. We especially focus on the tunability of the IF mechanics by environmental cues in these increasingly complex systems. In a series of experiments, including single filament elongation studies, single filament stretching measurements with optical tweezers, filament-filament interaction measurements with four optical tweezers, microrheology, and isotropic cell stretching, we characterize how electrostatic (pH and ion concentration) and hydrophobic interactions (detergent) provide various mechanisms by which the mechanics of the IF cytoskeleton can be tuned. These studies reveal how small changes, such as charge shifts, influence IF mechanics on multiple scales. In combination with simulations, we determine the mechanisms by which charge shifts alter single vimentin filament mechanics and we extract energy landscapes for interactions between single filaments. Such insights will provide a deeper understanding of the mechanisms by which cells can maintain their integrity and adapt to the mechanical requirements set by their environment.
Book Synopsis Physical Chemistry of Polymers by : Sebastian Seiffert
Download or read book Physical Chemistry of Polymers written by Sebastian Seiffert and published by Walter de Gruyter GmbH & Co KG. This book was released on 2020-04-20 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces the concepts of physical chemistry of polymers. It provides a basis to bridge polymer chemistry, which targets microscopic chain structures, and polymer engineering, which targets macroscopic material properties and functions. Topics covered are single chain statistics, multi-chain interactions, and chain dynamics, both from a viewpoint of structure, properties (mostly mechanical ones), and their interrelation. In all that, the author encourages the reader to think conceptually.
Book Synopsis Biophysical Regulation of Vascular Differentiation and Assembly by : Sharon Gerecht
Download or read book Biophysical Regulation of Vascular Differentiation and Assembly written by Sharon Gerecht and published by Springer Science & Business Media. This book was released on 2011-01-06 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because of their ability to differentiate and develop into functional vasculature, stem cells hold tremendous promise for therapeutic applications. However, the scientific understanding and the ability to engineer these cellular systems is still in its early stages, and must advance significantly for the therapeutic potential of stem cells to be realized. Stem cell differentiation and function are exquisitely tuned by their microenvironment. This book will provide a unique perspective of how different aspect of the vasculature microenvironment regulates differentiation and assembly. Recent efforts to exploits modern engineering techniques to study and manipulate various biophysical cues will be described including: oxygen tension during adult and embryonic vasculogenesis (Semenza and Zandstra), extracellular matrix during tube morphogenesis and angiogenesis (Wirtz, Davis, Ingber), surface topography and modification (Chen and Gerecht), shear stress and cyclic strain effect on vascular assembly and maturation (Vunjak-Novakovic and Niklason), and three dimensional space for angio-andvasculogensis (Ferreria and Fischbach).
Book Synopsis The Microrheology of Dispersions by : Harry Leonard Goldsmith
Download or read book The Microrheology of Dispersions written by Harry Leonard Goldsmith and published by . This book was released on 1965 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Advances in Food Rheology and Its Applications by : Jasim Ahmed
Download or read book Advances in Food Rheology and Its Applications written by Jasim Ahmed and published by Woodhead Publishing. This book was released on 2022-09-13 with total page 786 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Food Rheology and Its Applications: Development in Food Rheology, Second Edition presents the latest advances in the measurement and application of food rheology, one of the most important tools for food companies when characterizing ingredients and final products, and a predictor of product performance and consumer acceptance. This second edition provides coverage of new rheological measurement techniques, including ultrasonic measurements of rheological properties of food and NMR approach, and precision in data handling, including coverage of mathematical modeling of rheological properties. As the range of food products has also broadened as a result of consumer demands and preference, this second edition includes a series of new chapters on dairy and plant-based foods. The amalgamation between food texture and sensory attributes will also be addressed. In addition, coverage of the correlation between rheological behavior and modeling of the fluid in a human stomach and food digestion will be assessed. A special focus has given on rheology of gel systems, including, food hydrogels, bigel and organogels. Written for food scientists, food technologists, sensory scientists, and others working in academia and industry, Advances in Food Rheology and Its Applications: Development in Food Rheology, Second Edition will be a welcomed and updated reference. - Considers the impact of artificial intelligence and machine vision on rheological characterization and process control - Presents ultrasonic measurements of rheological properties of food and NMR approach, and precision in data handling - Covers thermodynamic approach of rheology and interfacial rheology - Explains various gel systems rheology, including bogels and organogo gels
Book Synopsis Colloidal Suspension Rheology by : Jan Mewis
Download or read book Colloidal Suspension Rheology written by Jan Mewis and published by Cambridge University Press. This book was released on 2012 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presented in an accessible and introductory manner, this is the first book devoted to the comprehensive study of colloidal suspensions.
Book Synopsis Correlation Force Spectroscopy for Single Molecule Measurements by : Milad Radiom
Download or read book Correlation Force Spectroscopy for Single Molecule Measurements written by Milad Radiom and published by Springer. This book was released on 2015-03-30 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis addresses the development of a new force spectroscopy tool, correlation force spectroscopy (CFS) for the measurement of the properties of very small volumes of material (molecular to μm3) at kHz-MHz frequency range. CFS measures the simultaneous thermal fluctuations of two closely-spaced atomic force microscopy (AFM) cantilevers. CFS then calculates the cross-correlation in the thermal fluctuations that gives the mechanical properties of the matter that spans the gap of the two cantilevers. The book also discusses development of CFS, its advantages over AFM, and its application in single molecule force spectroscopy and micro-rheology.
Download or read book Food Colloids written by Eric Dickinson and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 535 pages. Available in PDF, EPUB and Kindle. Book excerpt: Food structure at the molecular level and how it impacts on health, taste, texture and shelf life is becoming an increasingly important area of science. Food Colloids: Self-Assembly and Material Science describes new developments in the theory and practice of the formulation of food emulsions, dispersions, gels and foams. Particular emphasis is placed on the self-assembly of surfactants and biopolymers in food. Topics include: colloid science in food nutrition and the relationship of texture to sensory perception of food materials. It also discusses the exploitation of surfactant mesophases for nanoscale encapsulation, the interfacial rheological properties of mixed interfaces, the dynamics and microrheology of gels and emulsions, the stability of droplets and bubbles, the effects of thermal and mechanical processing on food colloid stability and the electrostatic interactions of proteins with polysaccharides. This authoritative book will serve as a guide and reference to researchers in the field of food colloids.
Book Synopsis Experimental and Computational Techniques in Soft Condensed Matter Physics by : Jeffrey Olafsen
Download or read book Experimental and Computational Techniques in Soft Condensed Matter Physics written by Jeffrey Olafsen and published by Cambridge University Press. This book was released on 2010-09-02 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Soft condensed matter physics relies on a fundamental understanding at the interface between physics, chemistry, biology, and engineering for a host of materials and circumstances that are related to, but outside, the traditional definition of condensed matter physics. Featuring contributions from leading researchers in the field, this book uniquely discusses both the contemporary experimental and computational manifestations of soft condensed matter systems. From particle tracking and image analysis, novel materials and computational methods, to confocal microscopy and bacterial assays, this book will equip the reader for collaborative and interdisciplinary research efforts relating to a range of modern problems in nonlinear and non-equilibrium systems. It will enable both graduate students and experienced researchers to supplement a more traditional understanding of thermodynamics and statistical systems with knowledge of the techniques used in contemporary investigations. Color versions of a selection of the figures are available at www.cambridge.org/9780521115902.
