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Microgravity And Vision Impairments In Astronauts
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Book Synopsis Microgravity and Vision Impairments in Astronauts by : Erik Seedhouse
Download or read book Microgravity and Vision Impairments in Astronauts written by Erik Seedhouse and published by Springer. This book was released on 2015-09-08 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent missions on board the International Space Station have revealed previously unreported physiological consequences of long duration space flight, particularly in eyesight, and in this Brief Dr. Seedhouse reviews the existing theories on what causes this degeneration and how long it will last. Notably, 60% of long-duration crews have reported subjective degradation in vision, a clear indication that further study is necessary before astronauts embark on even longer-term space missions. Decreased near-visual acuity was reported in 46% of ISS/Mir crewmembers, resulting in a change of up to 2 dioptres in their refractive correction. It is possible that ophthalmic changes have been present since the first days of spaceflight, but had been attributed to other causes; this approach to the issue as well as other hypotheses are all presented in full to give a broad foundation of the existing knowledge on the topic. The changes have occurred at various times during a mission with varying degrees of visual degradation. Some cases resolved on return to Earth, but several crewmembers have not regained pre-flight visual acuity, indicating the damage may be permanent. One explanation of the syndrome has been attributed to hyperopic shift due to aging, but onboard analysis techniques, including visual acuity assessments, retinal imagery, and ultrasound examination of the eye, has led to the acceptance of a wider syndrome. In addition to vision changes, studies have reported flattening of the globe, swelling of the optic disc (papilledema), choroidal folds in the retina, swelling of the optic nerve sheath, and visual field defects. It is widely hypothesized that this spectrum of symptoms may be explained by an elevation of intracranial pressure (ICP). Establishing the provenance of this medical problem, monitoring its occurrence and resolving the symptoms for future long term space missions is a key challenge for space medicine. With this book, readers have an entry point for understanding the full scope of the problem and its possible origins.
Author :Brandon R. Macias Publisher :World Scientific Publishing Company ISBN 13 :9789814667104 Total Pages :291 pages Book Rating :4.6/5 (671 download)
Book Synopsis Intracranial Pressure and Its Effect on Vision in Space and on Earth by : Brandon R. Macias
Download or read book Intracranial Pressure and Its Effect on Vision in Space and on Earth written by Brandon R. Macias and published by World Scientific Publishing Company. This book was released on 2017 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fluid distribution during spaceflight and impact on brain and vision health is an emerging field of high-priority research in the NASA human space program. International Space Station astronauts have developed ocular refraction changes during prolonged spaceflight. Within this book, experts review current data related to fluid shifts during microgravity exposure and the impact of fluid shifts on astronaut health. This work also compares current astronaut health problems with Earth-based health conditions such as elevated intracranial pressure and glaucoma. Chapters include discussion of altered fluid distribution, including intracellular and extracellular fluid shifts, eye morphology and vision disturbances, and intraocular pressure. In addition, chapters will include a discussion of advanced non-invasive technologies to investigate the abovementioned fluid volume and pressure variables. As such, the book aims to bridge health professionals, researchers, and science professionals by a presentation of ophthalmology topics critical to future human space exploration, thus providing new perspectives to solve emerging brain and eye disease on Earth and in Space.
Book Synopsis Spaceflight Associated Neuro-Ocular Syndrome by : Andrew G. Lee
Download or read book Spaceflight Associated Neuro-Ocular Syndrome written by Andrew G. Lee and published by Academic Press. This book was released on 2022-07-16 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prolonged microgravity exposure during long-duration spaceflight (LDSF) produces unusual physiologic and pathologic neuro-ophthalmic findings in astronauts. These microgravity-associated findings collectively define the Spaceflight Associated Neuro-ocular Syndrome (SANS). In this book, the editors compare and contrast prior published work on SANS by the National Aeronautics and Space Administration’s (NASA) Space Medicine Operations Division with retrospective and prospective studies from other research groups. The book describes the possible mechanisms and potential etiologies for SANS, and provides an update and review on the clinical manifestations of SANS including: unilateral and bilateral optic disc edema, globe flattening, choroidal and retinal folds, hyperopic refractive error shifts, and focal areas of ischemic retina (i.e., cotton wool spots). The ocular imaging findings (e.g., retinal nerve fiber layer, optic disc, and choroidal changes on optical coherence tomography) of SANS is also described, including the intraorbital and intracranial findings on orbital ultrasound and magnetic resonance imaging. The knowledge gaps for in-flight and terrestrial human research including potential countermeasures for future stud is also explored, including reports on the in-flight and terrestrial human and animal research being investigated by NASA and its partners to study SANS both prospectively and longitudinally and in preparation for future long duration manned missions to space including the moon, the asteroid belt, or Mars. We think this is a unique topic and hope that NASA and its research partners continue to study SANS in preparation for future longer duration manned space missions. Written in an easy-to-read manner, the book adopts a translational approach and explores the science and the clinical manifestations of Space flight associated neuro-ocular syndrome. It is also multi-disciplinary and suitable for both clinicians and researchers in ophthalmology, neurology, and aerospace medicine interested in SANS SANS is a unique space flight disorder that has no terrestrial equivalent. The book involves contributions from international experts across multiple disciplines to tackle the problem of SANS Summarizes and reviews the current findings of SANS, including possible mechanisms and potential etiologies, clinical manifestations, current reports on the in-flight and terrestrial human and animal research, and ocular imaging findings
Book Synopsis Intracranial Pressure and Its Effect on Vision in Space and on Earth by : Alan R. Hargens
Download or read book Intracranial Pressure and Its Effect on Vision in Space and on Earth written by Alan R. Hargens and published by . This book was released on 2017 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Fluid distribution during spaceflight and impact on brain and vision health is an emerging field of high-priority research in the NASA human space program. International Space Station astronauts have developed ocular refraction changes during prolonged spaceflight. Within this book, experts review current data related to fluid shifts during microgravity exposure and the impact of fluid shifts on astronaut health.This work also compares current astronaut health problems with Earth-based health conditions such as elevated intracranial pressure and glaucoma. Chapters include discussion of altered fluid distribution, including intracellular and extracellular fluid shifts, eye morphology and vision disturbances, and intraocular pressure. In addition, chapters will include a discussion of advanced non-invasive technologies to investigate the abovementioned fluid volume and pressure variables.As such, the book aims to bridge health professionals, researchers, and science professionals by a presentation of ophthalmology topics critical to future human space exploration, thus providing new perspectives to solve emerging brain and eye disease on Earth and in Space"--
Book Synopsis Safe Passage by : Institute of Medicine
Download or read book Safe Passage written by Institute of Medicine and published by National Academies Press. This book was released on 2001-11-20 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Safe Passage: Astronaut Care for Exploration Missions sets forth a vision for space medicine as it applies to deep space voyage. As space missions increase in duration from months to years and extend well beyond Earth's orbit, so will the attendant risks of working in these extreme and isolated environmental conditions. Hazards to astronaut health range from greater radiation exposure and loss of bone and muscle density to intensified psychological stress from living with others in a confined space. Going beyond the body of biomedical research, the report examines existing space medicine clinical and behavioral research and health care data and the policies attendant to them. It describes why not enough is known today about the dangers of prolonged travel to enable humans to venture into deep space in a safe and sane manner. The report makes a number of recommendations concerning NASA's structure for clinical and behavioral research, on the need for a comprehensive astronaut health care system and on an approach to communicating health and safety risks to astronauts, their families, and the public.
Book Synopsis Intraocular and Intracranial Pressure Gradient in Glaucoma by : Ningli Wang
Download or read book Intraocular and Intracranial Pressure Gradient in Glaucoma written by Ningli Wang and published by Springer. This book was released on 2019-03-30 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the characteristic of glaucomatous optic neuropathy and its relationship with cerebrospinal fluid (CSF) pressure. It also explores the potential novel methods to manage glaucoma by adjusting CSF pressure. This book covers several interesting topics such as why normal tension glaucoma (NTG) patients still develops into glaucoma without high intraocular pressure (IOP); and whether there are factors other than IOP contributing to the pathogenesis of NTG why the role of IOP in the pathogenesis of POAG becomes vague and controversial. This book contains over 40 chapters, including numerous images from clinical patients and experiments on gross anatomy, pathological tissue, and immunohistochemistry, electronic speculum etc. The ophthalmologists and researchers can also benefit from the clinical cases. We hope this book serves as a clinical guidance with practical significant for the understanding, prevention and diagnosis of glaucoma.
Book Synopsis Risk of Microgravity-Induced Visual Impairment and Elevated Intracranial Pressure by : Christian Otto
Download or read book Risk of Microgravity-Induced Visual Impairment and Elevated Intracranial Pressure written by Christian Otto and published by BiblioGov. This book was released on 2013-06 with total page 78 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eight cases identified, represent 23.5% of the 34 crewmembers flown on the ISS, with inflight visual changes and pre-to-postflight refractive changes. In some cases, the changes were transient while in others they are persistent with varying degrees of visual impairment. (1) Decreased intraocular pressure (IOP) postflight was observed in 3 cases. (2) Fundoscopic exams revealed postflight findings of choroidal folds in 4 cases, optic disc edema in 5 cases and presence of cotton wool spots in 3 cases. (3) Optical coherence tomography (OCT) confirmed findings of choroidal folds and disc edema and documented retinal nerve fiber layer thickening (4 cases). (4) Findings from MRI examinations showed posterior globe flattening (5 cases) and optic nerve sheath distension (6 cases). (5) Opening cerebrospinal fluid (CSF) pressure was elevated in 4 cases postflight reflecting raised intracranial pressure. While the etiology remains unknown, hypotheses speculate that venous insufficiency or hypertension in the brain caused by cephalad fluid shifts during spaceflight are possible mechanisms for ocular changes in astronauts.
Book Synopsis Safe Passage by : Institute of Medicine
Download or read book Safe Passage written by Institute of Medicine and published by National Academies Press. This book was released on 2001-12-20 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Safe Passage: Astronaut Care for Exploration Missions sets forth a vision for space medicine as it applies to deep space voyage. As space missions increase in duration from months to years and extend well beyond Earth's orbit, so will the attendant risks of working in these extreme and isolated environmental conditions. Hazards to astronaut health range from greater radiation exposure and loss of bone and muscle density to intensified psychological stress from living with others in a confined space. Going beyond the body of biomedical research, the report examines existing space medicine clinical and behavioral research and health care data and the policies attendant to them. It describes why not enough is known today about the dangers of prolonged travel to enable humans to venture into deep space in a safe and sane manner. The report makes a number of recommendations concerning NASA's structure for clinical and behavioral research, on the need for a comprehensive astronaut health care system and on an approach to communicating health and safety risks to astronauts, their families, and the public.
Book Synopsis Recapturing a Future for Space Exploration by : National Research Council
Download or read book Recapturing a Future for Space Exploration written by National Research Council and published by National Academies Press. This book was released on 2012-01-30 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than four decades have passed since a human first set foot on the Moon. Great strides have been made in our understanding of what is required to support an enduring human presence in space, as evidenced by progressively more advanced orbiting human outposts, culminating in the current International Space Station (ISS). However, of the more than 500 humans who have so far ventured into space, most have gone only as far as near-Earth orbit, and none have traveled beyond the orbit of the Moon. Achieving humans' further progress into the solar system had proved far more difficult than imagined in the heady days of the Apollo missions, but the potential rewards remain substantial. During its more than 50-year history, NASA's success in human space exploration has depended on the agency's ability to effectively address a wide range of biomedical, engineering, physical science, and related obstacles-an achievement made possible by NASA's strong and productive commitments to life and physical sciences research for human space exploration, and by its use of human space exploration infrastructures for scientific discovery. The Committee for the Decadal Survey of Biological and Physical Sciences acknowledges the many achievements of NASA, which are all the more remarkable given budgetary challenges and changing directions within the agency. In the past decade, however, a consequence of those challenges has been a life and physical sciences research program that was dramatically reduced in both scale and scope, with the result that the agency is poorly positioned to take full advantage of the scientific opportunities offered by the now fully equipped and staffed ISS laboratory, or to effectively pursue the scientific research needed to support the development of advanced human exploration capabilities. Although its review has left it deeply concerned about the current state of NASA's life and physical sciences research, the Committee for the Decadal Survey on Biological and Physical Sciences in Space is nevertheless convinced that a focused science and engineering program can achieve successes that will bring the space community, the U.S. public, and policymakers to an understanding that we are ready for the next significant phase of human space exploration. The goal of this report is to lay out steps and develop a forward-looking portfolio of research that will provide the basis for recapturing the excitement and value of human spaceflight-thereby enabling the U.S. space program to deliver on new exploration initiatives that serve the nation, excite the public, and place the United States again at the forefront of space exploration for the global good.
Book Synopsis Intracranial Pressure & Neuromonitoring XVI by : Thomas Heldt
Download or read book Intracranial Pressure & Neuromonitoring XVI written by Thomas Heldt and published by Springer. This book was released on 2018-02-28 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces the latest advances relating to the pathophysiology, biophysics, monitoring and treatment of traumatic brain injury, hydrocephalus, and stroke presented at the 16th International Conference on Intracranial Pressure and Neuromonitoring (the "ICP Conference"), held in Cambridge, Massachusetts, in June 2016 in conjunction with the 6th Annual Meeting of the Cerebral Autoregulation Research Network. Additionally, the conference held special sessions on neurocritical care informatics and cerebrovascular autoregulation. The peer-reviewed papers included were written by leading experts in neurosurgery, neurointensive care, anesthesiology, physiology, clinical engineering, clinical informatics and mathematics who have made important contributions in this translational area of research, and their focus ranges from the latest research findings and developments to clinical trials and experimental studies. The book continues the proud tradition of publishing key work from the ICP Conferences and is a must-read for anyone wishing to stay abreast of recent advances in the field.
Download or read book Into Space written by Thais Russomano and published by BoD – Books on Demand. This book was released on 2018-05-30 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our anatomy and physiology have been completely shaped by Earth's gravity. All body systems function in synergy with this unseen force. Yet, as we journey further and longer into space, our bodies must conform to a new reality, wherein gravity is absent or reduced, cosmic radiation threatens and our social and familial connections become distant. Into Space: A Journey of How Humans Adapt and Live in Microgravity gives an overview of some of the physiological, anatomical and cellular changes that occur in space and their effects on different body systems, such as the cardiovascular and musculoskeletal, and touches on cultural and psychosocial aspects of leaving behind family and the safety of Earth. It further addresses the complexity of manned space flights, showing how interdisciplinary this subject is and discussing the challenges that space physiologists, physicians and scientists must face as humans seek to conquer the final frontier.
Book Synopsis Handbook of Space Pharmaceuticals by : Yashwant Pathak
Download or read book Handbook of Space Pharmaceuticals written by Yashwant Pathak and published by Springer. This book was released on 2022-05-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume handbook, directed at medical professionals and students who are involved in developing the space industry or are academicians doing research in this area, covers current pharmaceutical knowledge about the difference in medication efficacy in space versus on Earth and includes trial results and best practices for the space research and travel industry. The well-known contributors come from an interdisciplinary background and address all aspects of the subject, from the physiological impact of spaceflight to the effects of radiation. As the commercial space industry expands its operations in industry and tourism, the field of space pharmaceuticals is growing commensurately. Existing pharmacological research from space is thoroughly covered in this book, and Earth applications are also described. Potential pharmacological solutions are posed along with the known challenges and examples from existing studies, which are detailed at length. This major reference work is a comprehensive and important medical resource for all space industry players.
Book Synopsis Integrative Ophthalmology by : Ningli Wang
Download or read book Integrative Ophthalmology written by Ningli Wang and published by Springer Nature. This book was released on 2019-09-05 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the development of nature science and industrial technology, more and more patients are benefitting from the rapid progress in ophthalmology, as the use of new medicine and delicate surgical therapy has ensured them the chance to restore their sight. However, some problems have come up during its development, of which the most serious one is the limitation of the ophthalmology. Eyes are not isolated organs, they are connected to our body, and thus, the general status of our body will affect the eyes’ function. Therefore, it is of great importance that the ophthalmologists see the big picture while dealing with the clinical problems. Based on the above observations, we put forward the concept of Integrative Ophthalmology, and describe the ophthalmology related medical situations that are prone to be neglected in clinical practice in a bid to increase the awareness of doctors from all fields that a holistic view should be adopted in clinical practice, and it is the patients that we are treating rather than the disease. There are 9 parts in the book, containing the concept of integrative ophthalmology, intraocular and intracranial pressure gradient related diseases,and the relationship between the different general status and eye disorders. We do believe that the integrative ophthalmology is the key to the development of ophthalmology and hope readers can benefit from this book.
Book Synopsis Human Health and Performance Risks of Space Exploration Missions by : Jancy C. McPhee
Download or read book Human Health and Performance Risks of Space Exploration Missions written by Jancy C. McPhee and published by U. S. National Aeronautics & Space Administration. This book was released on 2009 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Space Safety and Human Performance by : Barbara G. Kanki
Download or read book Space Safety and Human Performance written by Barbara G. Kanki and published by Butterworth-Heinemann. This book was released on 2017-11-10 with total page 946 pages. Available in PDF, EPUB and Kindle. Book excerpt: Space Safety and Human Performance provides a comprehensive reference for engineers and technical managers within aerospace and high technology companies, space agencies, operators, and consulting firms. The book draws upon the expertise of the world’s leading experts in the field and focuses primarily on humans in spaceflight, but also covers operators of control centers on the ground and behavior aspects of complex organizations, thus addressing the entire spectrum of space actors. During spaceflight, human performance can be deeply affected by physical, psychological and psychosocial stressors. Strict selection, intensive training and adequate operational rules are used to fight performance degradation and prepare individuals and teams to effectively manage systems failures and challenging emergencies. The book is endorsed by the International Association for the Advancement of Space Safety (IAASS). 2019 PROSE Awards - Winner: Category: Engineering and Technology: Association of American Publishers Provides information on critical aspects of human performance in space missions Addresses the issue of human performance, from physical and psychosocial stressors that can degrade performance, to selection and training principles and techniques to enhance performance Brings together essential material on: cognition and human error; advanced analysis methods such as human reliability analysis; environmental challenges and human performance in space missions; critical human factors and man/machine interfaces in space systems design; crew selection and training; and organizational behavior and safety culture Includes an endorsement by the International Association for the Advancement of Space Safety (IAASS)
Book Synopsis Space Physiology and Medicine by : Arnauld E. Nicogossian
Download or read book Space Physiology and Medicine written by Arnauld E. Nicogossian and published by . This book was released on 1982 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: 2009 life science book award from IAA.
Book Synopsis Review of NASA's Longitudinal Study of Astronaut Health by : Institute of Medicine
Download or read book Review of NASA's Longitudinal Study of Astronaut Health written by Institute of Medicine and published by National Academies Press. This book was released on 2004-05-27 with total page 93 pages. Available in PDF, EPUB and Kindle. Book excerpt: As part of its ongoing commitment to the nation's space program, NASA's medical leadership asked the Institute of Medicine (IOM) to review specific aspects of the scientific basis, policies, and procedures associated with the Longitudinal Study of Astronaut Health (LSAH). NASA created the LSAH in 1992 to address a variety of issues, including both the health of astronauts during space flight and the longer-term health issues that might be associated with space flight and flight training.
