Microbial Cell Cycle

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The Bacterial Cell: Coupling between Growth, Nucleoid Replication, Cell Division, and Shape, Volume 2

Author : Ariel Amir
Publisher : Frontiers Media SA
ISBN 13 : 2889631567
Total Pages : 246 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis The Bacterial Cell: Coupling between Growth, Nucleoid Replication, Cell Division, and Shape, Volume 2 by : Ariel Amir

Download or read book The Bacterial Cell: Coupling between Growth, Nucleoid Replication, Cell Division, and Shape, Volume 2 written by Ariel Amir and published by Frontiers Media SA. This book was released on 2019-11-14 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 1st volume of our Research Topic "The Bacterial Cell: Coupling between Growth, Nucleoid Replication, Cell Division and Shape” was published as an eBook in May 2016 (see: http://journal.frontiersin.org/researchtopic/2905/the-bacterial-cell-coupling-between-growth-nucleoid-replication-cell-division-and-shape). As a sign of growing interest to the topic, two workshops followed the same year: "Stochasticity in the Cell Cycle" in Jerusalem (Israel) by the Hebrew University’s Institute of Advanced Studies and EMBO's "Cell Size Regulation" in Joachimsthal (Germany). From the time of launching the first edition, several new groups have entered the field, and many established groups have made significant advances using state-of-the-art microscopy and microfluidics. Combining these approaches with the techniques pioneered by quantitative microbiologists decades ago, these approaches have provided remarkable amounts of numerical data. Most of these data needed yet to be put into a broader theoretical perspective. Moreover, the molecular mechanisms governing coordination and progression of the main bacterial cell cycle processes have remained largely unknown. These outstanding fundamental questions and the growing interest to the field motivated us to launch the next volume titled “The Bacterial Cell: Coupling between Growth, Nucleoid Replication, Cell Division, and Shape, Volume 2” shortly after completion of the first edition in October 2016. The issue contains 17 contributions from a diverse array of scientists whose field of study spans microbiology, biochemistry, genetics, experimental and theoretical biophysics. The specific questions addressed in the issue include: What triggers initiation of chromosome replication? How is cell division coordinated with replication both spatially and temporally? How is cell size controlled and linked to the rate of mass growth? What role plays physical organization of the chromosomes in their segregation and in regulation of cell division? The publications covering these questions are divided into three topical areas: 1) Cell Cycle Regulation, 2) Growth and Division, and 3) Nucleoid Structure and Replication. New ideas and techniques put forward in these articles bring us closer to understand these fundamental cellular processes, but the quest to resolve them is far from being complete. Plans for the next edition are under way along with further meetings and workshops, e.g., an EMBO Workshop on Bacterial cell biophysics: DNA replication, growth, division, size and shape in Ein Gedi (Israel), May 2020. We hope that via such interdisciplinary exchange of ideas we will come closer to answering the above-mentioned complex and multifaceted questions.

The Microbial Cell Cycle

Author : Clive Arthur Edwards
Publisher :
ISBN 13 :
Total Pages : 104 pages
Book Rating : 4.3/5 (129 download)

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Book Synopsis The Microbial Cell Cycle by : Clive Arthur Edwards

Download or read book The Microbial Cell Cycle written by Clive Arthur Edwards and published by . This book was released on 1981 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt:

MICROBIAL CELL CYCLE

Author : Streiblva
Publisher : Springer
ISBN 13 :
Total Pages : 296 pages
Book Rating : 4.:/5 (44 download)

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Book Synopsis MICROBIAL CELL CYCLE by : Streiblva

Download or read book MICROBIAL CELL CYCLE written by Streiblva and published by Springer. This book was released on 1984-05-02 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Eukaryotic Cell Cycle

Author : J. A. Bryant
Publisher : Taylor & Francis US
ISBN 13 :
Total Pages : 352 pages
Book Rating : 4.X/5 (3 download)

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Book Synopsis The Eukaryotic Cell Cycle by : J. A. Bryant

Download or read book The Eukaryotic Cell Cycle written by J. A. Bryant and published by Taylor & Francis US. This book was released on 2008 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by respected researchers, this is an excellent account of the eukaryotic cell cycle that is suitable for graduate and postdoctoral researchers. It discusses important experiments, organisms of interest and research findings connected to the different stages of the cycle and the components involved.

The Microbial Cell Cycle

Author : Clive Arthur Edwards
Publisher :
ISBN 13 : 9780442307783
Total Pages : 88 pages
Book Rating : 4.3/5 (77 download)

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Book Synopsis The Microbial Cell Cycle by : Clive Arthur Edwards

Download or read book The Microbial Cell Cycle written by Clive Arthur Edwards and published by . This book was released on 1981-01-01 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Bacterial Cell: Coupling between Growth, Nucleoid Replication, Cell Division and Shape

Author : Arieh Zaritsky
Publisher : Frontiers Media SA
ISBN 13 : 2889198170
Total Pages : 326 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis The Bacterial Cell: Coupling between Growth, Nucleoid Replication, Cell Division and Shape by : Arieh Zaritsky

Download or read book The Bacterial Cell: Coupling between Growth, Nucleoid Replication, Cell Division and Shape written by Arieh Zaritsky and published by Frontiers Media SA. This book was released on 2016-05-02 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacterial Physiology was inaugurated as a discipline by the seminal research of Maaløe, Schaechter and Kjeldgaard published in 1958. Their work clarified the relationship between cell composition and growth rate and led to unravel the temporal coupling between chromosome replication and the subsequent cell division by Helmstetter et al. a decade later. Now, after half a century this field has become a major research direction that attracts interest of many scientists from different disciplines. The outstanding question how the most basic cellular processes - mass growth, chromosome replication and cell division - are inter-coordinated in both space and time is still unresolved at the molecular level. Several particularly pertinent questions that are intensively studied follow: (a) what is the primary signal to place the Z-ring precisely between the two replicating and segregating nucleoids? (b) Is this coupling related to the structure and position of the nucleoid itself? (c) How does a bacterium determine and maintain its shape and dimensions? Possible answers include gene expression-based mechanisms, self-organization of protein assemblies and physical principles such as micro-phase separations by excluded volume interactions, diffusion ratchets and membrane stress or curvature. The relationships between biochemical reactions and physical forces are yet to be conceived and discovered. This e-book discusses the above mentioned and related questions. The book also serves as an important depository for state-of-the-art technologies, methods, theoretical simulations and innovative ideas and hypotheses for future testing. Integrating the information gained from various angles will likely help decipher how a relatively simple cell such as a bacterium incorporates its multitude of pathways and processes into a highly efficient self-organized system. The knowledge may be helpful in the ambition to artificially reconstruct a simple living system and to develop new antibacterial drugs.

The Cell Cycle

Author : G. M. Padilla
Publisher : Academic Press
ISBN 13 : 1483274500
Total Pages : 420 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis The Cell Cycle by : G. M. Padilla

Download or read book The Cell Cycle written by G. M. Padilla and published by Academic Press. This book was released on 2013-09-11 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Cell Cycle: Gene Enzyme Interactions presents the primary regulatory mechanisms of the cell cycle. This book provides theoretical and methodological discussions concerning cell cycles. Organized into 17 chapters, this book begins with an overview of cell evolution and thermodynamics. This text then examines the regulation of initiation of chromosome replication, and the coordination between this event and cell division, in Escherichia coli. Other chapters consider the operon model for the control of genetic expression in bacterial cells, which provides an understanding of the regulatory mechanisms of gene function. This book discusses as well the observations and experiments on the timing of events in the cell cycles of some bacteria and attempts to provide explanations in terms of established control systems. The final chapter deals with DNA markers, which serve as a convenient starting point for exploring the general principles of cell cycle markers. This book is a valuable resource for cell biologists.

Bacterial Growth and Division

Author : Stephen Cooper
Publisher : Elsevier
ISBN 13 : 008091747X
Total Pages : 528 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Bacterial Growth and Division by : Stephen Cooper

Download or read book Bacterial Growth and Division written by Stephen Cooper and published by Elsevier. This book was released on 2012-12-02 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: How does a bacterial cell grow during the division cycle? This question is answered by the codeveloper of the Cooper-Helmstetter model of DNA replication. In a unique analysis of the bacterial division cycle, Cooper considers the major cell categories (cytoplasm, DNA, and cell surface) and presents a lucid description of bacterial growth during the division cycle. The concepts of bacterial physiology from Ole Maaløe's Copenhagen school are presented throughout the book and are applied to such topics as the origin of variability, the pattern of DNA segregation, and the principles underlying growth transitions. The results of research on E. coli are used to explain the division cycles of Caulobacter, Bacilli, Streptococci, and eukaryotes. Insightful reanalysis highlights significant similarities between these cells and E.coli. With over 25 years of experience in the study of the bacterial division cycle, Cooper has synthesized his ideas and research into an exciting presentation. He manages to write a comprehensive volume that will be of great interest to microbiologists, cell physiologists, cell and molecular biologists, researchers in cell-cycle studies, and mathematicians and engineering scientists interested in modeling cell growth. Written by one of the codiscoverers of the Cooper-Helmstetter model Applies the results of research on E. coli to other groups, including Caulobacter, Bacilli, Streptococci, and eukaryotes; the Caulobacter reanalysis highlights significant similarities with the E. coli system Presents a unified description of the bacterial division cycle with relevance to eukaryotic systems Addresses the concepts of the Copenhagen School in a new and original way

Molecules in Time and Space

Author : Miguel Vicente
Publisher : Springer Science & Business Media
ISBN 13 : 0306485796
Total Pages : 275 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis Molecules in Time and Space by : Miguel Vicente

Download or read book Molecules in Time and Space written by Miguel Vicente and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last decade a wealth of new data has arisen from the use of new fluorescent labelling techniques and the sequencing of whole microbial genomes. One important conclusion from these data is that bacterial cells are much more structured than previously thought. The wall and the outer membrane contain topological domains, some proteins localize or move in specific patterns inside the cells, and some genes appear clustered in the chromosome and form conserved evolutionary units. Many of these structures are related to the cell cycle and to the process of cell morphogenesis, two processes that are themselves related to each other. From these observations the dcw gene cluster appears as a phylogenetic trait that is mainly conserved in bacilli. Molecules in Time and Space reviews the data on the formation of subcellular patterns or structures in bacteria, presents observations and hypotheses on the establishment and the maintenance of cell shape, and on the organization of genetic information in the chromosome.

Bacterial Growth and Form

Author : A.L. Koch
Publisher : Springer Science & Business Media
ISBN 13 : 9401708274
Total Pages : 470 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Bacterial Growth and Form by : A.L. Koch

Download or read book Bacterial Growth and Form written by A.L. Koch and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: I assume that you already know a good deal of microbiology. In this book, I frequently use the word "we" by which I mean "you and I". Together we are going to consider bacteriology from a broader perspective and we will think our way through the important biological problems that are frequently just skipped over in every microbiology course. My most important reason for writing this book is to make accessible the relevant thinking from fields of science other than microbiology that are important to microbiology. The book is written for people that have already have a fascination with bacteria, but can see that their background for understanding is far complete. This book consists of topics that are largely omitted from microbiology textbooks and includes some mathematics, physics, chemistry, and evolutionary biology. It contains a good deal of my own work, both experimental and theoretical, together with a lot of speculation. If ten times bigger, it would be a full text book on microbial physiology. A third of the microbial physiology is covered by the recent is no longer treated even in textbook by White (2000). Another third current specialized tests and is greatly underrepresented in text books.

The Cell Division Cycle

Author : David Lloyd
Publisher :
ISBN 13 :
Total Pages : 536 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis The Cell Division Cycle by : David Lloyd

Download or read book The Cell Division Cycle written by David Lloyd and published by . This book was released on 1982 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Concepts of Biology

Author : Samantha Fowler
Publisher :
ISBN 13 : 9781680921021
Total Pages : 624 pages
Book Rating : 4.9/5 (21 download)

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Book Synopsis Concepts of Biology by : Samantha Fowler

Download or read book Concepts of Biology written by Samantha Fowler and published by . This book was released on 2017-12-30 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concepts of Biology is designed for the introductory biology course for nonmajors taught at most two- and four-year colleges. The scope, sequence, and level of the program are designed to match typical course syllabi in the market. Concepts of Biology includes interesting applications, features a rich art program, and conveys the major themes of biology. The images in this textbook are grayscale.

DNA Replication Control in Microbial Cell Factories

Author : Monika Glinkowska
Publisher : Springer
ISBN 13 : 3319105337
Total Pages : 56 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis DNA Replication Control in Microbial Cell Factories by : Monika Glinkowska

Download or read book DNA Replication Control in Microbial Cell Factories written by Monika Glinkowska and published by Springer. This book was released on 2014-09-23 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work describes the current knowledge of biochemical mechanisms regulating initiation of DNA replication in Escherichia coli, which focuses on the control of activity of the DnaA protein. Examples of direct linkages between DNA replication and other cellular processes are provided. In addition, similarities of the mechanisms of regulation of DNA replication operating in prokaryotic and eukaryotic cells are identified, and implications for understanding more complex processes, like carcinogenesis are suggested. Studies of recent years provided evidence that regulation of DNA replication in bacteria is more complex than previously anticipated. Multiple layers of control seem to ensure coordination of this process with the increase of cellular mass and the division cycle. Metabolic processes and membrane composition may serve as points where integration of genome replication with growth conditions occurs. It is also likely that coupling of DNA synthesis with cellular metabolism may involve interactions of replication proteins with other macromolecular complexes, responsible for various cellular processes. Thus, the exact set of factors participating in triggering the replication initiation may differ depending on growth conditions. Therefore, understanding the regulation of DNA duplication requires placing this process in the context of the current knowledge on bacterial metabolism, as well as cellular and chromosomal structure. Moreover, in both Escherichia coli and eukaryotic cells, replication initiator proteins were shown to play other roles in addition to driving the assembly of replication complexes, which constitutes another, yet not sufficiently understood, layer of coordinating DNA replication with the cell cycle.

The Relationship Between Size, Growth Rate, and the Cell Cycle in Bacteria

Author : Norbert Seabrook Hill
Publisher :
ISBN 13 :
Total Pages : 228 pages
Book Rating : 4.:/5 (858 download)

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Book Synopsis The Relationship Between Size, Growth Rate, and the Cell Cycle in Bacteria by : Norbert Seabrook Hill

Download or read book The Relationship Between Size, Growth Rate, and the Cell Cycle in Bacteria written by Norbert Seabrook Hill and published by . This book was released on 2013 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA replication, nucleoid segregation, and cell division must be coordinated with growth and cell size to ensure viability in all organisms. Failure to do so yields progeny with an inappropriate fraction of genetic and cytosolic material, reducing the fitness of the organism. This dissertation has sought to understand the role of cell size in two fundamental aspects of bacterial physiology: 1) How do bacteria regulate cell size in response to nutrient availability? 2) Does cell size govern progression of the cell cycle? Growth rate and nutrient availability are primary determinants of cell size in single-celled organisms. Bacterial cells cultured in nutrient-rich circumstances are twice the size of cells grown in nutrient-poor conditions. How bacteria are able to perceive nutrient levels and amend cell size is largely undefined. In Chapter 2, I report the identification and characterization of the glucosyltransferase OpgH as a uridine diphosphate (UDP) glucose-dependent effector that coordinates Escherichia coli cell size with growth rate and nutritional status. High intracellular levels of UDP-glucose accumulate during growth in nutrient-rich conditions. In turn, UDP-glucose activates OpgH to sequester the essential division protein FtsZ, which obstructs assembly and/or maturation of the cytokinetic ring, delaying division to increase cell size. In this way, OpgH directly gauges nutrient status and modifies cell size through the timing of division. Cell cycle progression is regulated by cell size in all organisms. In bacteria, it has long been postulated that the achievement of a particular cell size triggers chromosomal replication. Chapter 3 of this dissertation describes a comparative study between E. coli and Bacillus subtilis examining whether cell mass determines the timing of initiation of DNA replication. Using mutants defective for cell size, my data confirms that E. coli directly ties the initiation event to cell mass. However, counter to the paradigm, the phenomenon of initiation mass is not conserved to B. subtilis, which appears to coordinate DNA replication through a cell cycle timer device. This dissertation yields several original conclusions. First, the discovery of OpgH as a UDP-glucose-activated antagonist of FtsZ polymerization is a significant advance in the understanding of cell size control in bacteria. However, these results in tandem with the cognate pathway in B. subtilis reveal a remarkable instance of convergent evolution. Based on this, I propose that UDP-glucose and cognate UDP-glucose binding proteins are a widely conserved strategy to direct nutrient-dependent changes in cell size. In addition, the revelation that initiation of DNA replication is cell size-independent in B. subtilis adds to a growing sentiment that mechanisms controlling DNA replication are fundamentally divergent throughout bacteria.

Cell Cycle Regulation and Development in Alphaproteobacteria

Author : Emanuele Biondi
Publisher : Springer Nature
ISBN 13 : 3030906213
Total Pages : 305 pages
Book Rating : 4.0/5 (39 download)

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Book Synopsis Cell Cycle Regulation and Development in Alphaproteobacteria by : Emanuele Biondi

Download or read book Cell Cycle Regulation and Development in Alphaproteobacteria written by Emanuele Biondi and published by Springer Nature. This book was released on 2022-03-14 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the cell cycle regulation and development in Alphaproteobacteria. Cell cycle and cellular differentiation are fascinating biological phenomena that are highly regulated in all organisms. In the last decades, many laboratories around the world have been investigating these processes in Alphaproteobacteria. This bacterial class comprises important bacterial species, studied by fundamental and applied research. The complexity of cell cycle regulation and many examples of cellular differentiations in this bacterial group represent the main motives of this book. The book starts with discussing the regulation of cell cycle in alphaproteobacterial species from a system biology perspective. The following chapters specifically focus on the model species Caulobacter crescentus multiple layers of regulation, from transcriptional cascades to proteolysis and dynamic subcellular regulation of cell cycle regulators. In addition, the cell division process, chromosome segregation and growth of the cell envelope is described in detail. The last part of the book covers examples of non-Caulobacter alphaproteobacterial models, such as Agrobacterium tumefaciens, Brucella species and Sinorhizobium meliloti and also discusses possible applications. This book will be of interest to researchers in microbiology and cell biology labs working on cell cycle regulation and development.

Molecular Biology of the Cell

Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Microbial Physiology

Author : Albert G. Moat
Publisher : John Wiley & Sons
ISBN 13 : 0471461199
Total Pages : 715 pages
Book Rating : 4.4/5 (714 download)

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Book Synopsis Microbial Physiology by : Albert G. Moat

Download or read book Microbial Physiology written by Albert G. Moat and published by John Wiley & Sons. This book was released on 2003-03-31 with total page 715 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Fourth Edition of Microbial Physiology retains the logical, easy-to-follow organization of the previous editions. An introduction to cell structure and synthesis of cell components is provided, followed by detailed discussions of genetics, metabolism, growth, and regulation for anyone wishing to understand the mechanisms underlying cell survival and growth. This comprehensive reference approaches the subject from a modern molecular genetic perspective, incorporating new insights gained from various genome projects.