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Author : Bengt Fadeel
Publisher : Frontiers Media SA
ISBN 13 : 2832511856
Total Pages : 90 pages
Book Rating : 4.8/5 (325 download)
Download or read book Methods and protocols in nanotoxicology written by Bengt Fadeel and published by Frontiers Media SA. This book was released on 2023-01-27 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Qunwei Zhang
Publisher :
ISBN 13 : 9781493989164
Total Pages : 371 pages
Book Rating : 4.9/5 (891 download)
Download or read book Nanotoxicity written by Qunwei Zhang and published by . This book was released on 2018 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Vineet Kumar
Publisher : Springer Nature
ISBN 13 : 3030694925
Total Pages : 305 pages
Book Rating : 4.0/5 (36 download)
Download or read book Nanotoxicology and Nanoecotoxicology Vol. 2 written by Vineet Kumar and published by Springer Nature. This book was released on 2021-05-25 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews advances in the toxicity of nanomaterials, with a focus on nanosensors and nanotoxicity testing, biomagnification, biotransformation, nanosafety, genotoxicity, human health and remediation. This is the second volume on Nanotoxicology and Nanoecotoxicology published in the book series Environmental Chemistry for a Sustainable World.
Author : Stephen R. Grobmyer
Publisher : Humana Press
ISBN 13 : 9781607616085
Total Pages : 0 pages
Book Rating : 4.6/5 (16 download)
Download or read book Cancer Nanotechnology written by Stephen R. Grobmyer and published by Humana Press. This book was released on 2010-03-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Early detection of cancer at the cellular level, even before anatomic anomalies are visible, is critical to more efficacious and cost effective diagnosis and therapeutic advances. In Cancer Nanotechnology: Methods and Protocols, an international panel of experts provide the most recent, cutting-edge, "how-to" approaches developed and employed by researchers in a variety of disciplines to identify cancer specific biomarkers, construct suitable multifunctional targeted nanostructure platforms, along with enhanced imaging and therapeutic applications. Covering such topics as multifunctional and multimodal nanoparticles, nanoparticle mediated cancer theranostics, molecular targets for cancer nanotechnology, and nanoparticles for non-invasive image-guided cancer therapy, the volume addresses the key challenges of the field today, specifically targeted and localized delivery of the drugs. As a volume in the highly successful Methods in Molecular BiologyTM series, the protocols chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cancer Nanotechnology: Methods and Protocols integrates cancer biology, clinical oncology, molecular cancer imaging, materials science and chemical engineering, biomedical engineering, toxicology, computer science, electrical engineering, chemistry, physics, and mathematics in order to achieve the vital goals of nanotechnology-mediated early cancer detection and more efficacious and less toxic therapies for these devastating diseases.
Author : Alok Dhawan
Publisher : Royal Society of Chemistry
ISBN 13 : 1788012593
Total Pages : 380 pages
Book Rating : 4.7/5 (88 download)
Download or read book Nanotoxicology written by Alok Dhawan and published by Royal Society of Chemistry. This book was released on 2017-11-03 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapid expansion of the nanotechnology field raises concerns, like any new technology, about the toxicity and environmental impact of nanomaterials. This book addresses the gaps relating to health and safety issues of this field and aims to bring together fragmented knowledge on nanosafety. Not only do chapters address conventional toxicity issues, but also more recent developments such as food borne nanoparticles, life cycle analysis of nanoparticles and nano ethics. In addition, the authors discuss the environmental impact of nanotechnologies as well as safety guidelines and ethical issues surrounding the use of nanoparticles. In particular this book presents a unique compilation of experimental and computational perspectives and illustrates the use of computational models as a support for experimental work. Nanotoxicology: Experimental and Computational Perspectives is aimed towards postgraduates, academics, and practicing industry professionals. This highly comprehensive review also serves as an excellent foundation for undergraduate students and researchers new to nanotechnology and nanotoxicology. It is of particular value to toxicologists working in nanotechnology, chemical risk assessment, food science, environmental, safety, chemical engineering, the biological sciences and pharmaceutical research.
Author : Vineet Kumar
Publisher : CRC Press
ISBN 13 : 1351138197
Total Pages : 703 pages
Book Rating : 4.3/5 (511 download)
Download or read book Nanotoxicology written by Vineet Kumar and published by CRC Press. This book was released on 2018-03-12 with total page 703 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the application of nanotechnology in the myriad disciplines of science and engineering--from agriculture, pharmaceuticals, material science, and biotechnology to sensors, electronics, and mechanical and electrical engineering--brings benefits it also can produce serious threats to human health and the environment that must be evaluated. The unique properties of nanomaterials make them different from their bulk counterparts. In addition to such unique properties, the nanometric size of nanomaterials can invite some detrimental effects on the health and well-being of living organisms and the environment. Thus, it is important to distinguish nanomaterials with such ill effects from nanomaterials with no or minimum toxicity. Nanotoxicology: Toxicity Evaluation, Risk Assessment and Management covers issues such as the basic principles of nanotoxicity, methods used for nanotoxicity evaluation, risk assessment and its management for nanomaterial toxicity with a focus on current trends, limitations, challenges, and future directions of nanotoxicity evaluation. Various experts from different countries discuss these issues in detail in this book. This will be helpful to researchers, educators, and students who are interested in research opportunities for avoiding the environmental and health hazards of nanomaterials. This book will also be useful for industrial practitioners, policy makers, and other professionals in the fields of toxicology, medicine, pharmacology, food, drugs, and other regulatory sciences.
Author : Surendra Nimesh
Publisher : Woodhead Publishing
ISBN 13 : 0081005636
Total Pages : 258 pages
Book Rating : 4.0/5 (81 download)
Download or read book Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids written by Surendra Nimesh and published by Woodhead Publishing. This book was released on 2017-04-04 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles mediated NA would be discussed, with focus on their clinical relevance. The design and development of nucleic acid-based therapeutics for the treatment of diseases arising from genetic abnormalities has made significant progress over the past few years. NAs have been widely explored for the treatment of cancer and infectious diseases or to block cell proliferation and thereby caused diseases. Advances in synthetic oligonucleotide chemistry resulted in synthesis of NAs that are relatively stable in in vivo environments. However, cellular targeting and intracellular delivery of NAs still remains a challenge. Further development of NA-based therapeutics depends on the progress of safe and effective carriers for systemic administration. Nanomedicine has facilitated availability of vectors with diminished cytotoxicity and enhanced efficacy which are rapidly emerging as systems of choice. These vectors protect NAs from enzymatic degradation by forming condensed complexes along with targeted tissue and cellular delivery. During the past few years, a myriad reports have appeared reporting delivery of NAs mediated by nanoparticles. This book will provide an overview of nanoparticles being employed in the in vitro and in vivo delivery of therapeutically relevant NAs like DNA, siRNA, LNA, PNA, etc. - Provides a complete overview of the applicatiosn of nanomedicine in the delivery of nucleic acids, from characterization of nanoparticles, to in vitro and in vivo studies - Discusses delivery issues of less well explored nucleic acids, like PNAs, Ribozymes, DNAzymes, etc. - Summarizes the current state of research in nucleic acid delivery and underscores the future of nanomedicine in this field
Author : Vineet Kumar
Publisher : CRC Press
ISBN 13 : 1351138189
Total Pages : 610 pages
Book Rating : 4.3/5 (511 download)
Download or read book Nanotoxicology written by Vineet Kumar and published by CRC Press. This book was released on 2018-03-12 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the application of nanotechnology in the myriad disciplines of science and engineering--from agriculture, pharmaceuticals, material science, and biotechnology to sensors, electronics, and mechanical and electrical engineering--brings benefits it also can produce serious threats to human health and the environment that must be evaluated. The unique properties of nanomaterials make them different from their bulk counterparts. In addition to such unique properties, the nanometric size of nanomaterials can invite some detrimental effects on the health and well-being of living organisms and the environment. Thus, it is important to distinguish nanomaterials with such ill effects from nanomaterials with no or minimum toxicity. Nanotoxicology: Toxicity Evaluation, Risk Assessment and Management covers issues such as the basic principles of nanotoxicity, methods used for nanotoxicity evaluation, risk assessment and its management for nanomaterial toxicity with a focus on current trends, limitations, challenges, and future directions of nanotoxicity evaluation. Various experts from different countries discuss these issues in detail in this book. This will be helpful to researchers, educators, and students who are interested in research opportunities for avoiding the environmental and health hazards of nanomaterials. This book will also be useful for industrial practitioners, policy makers, and other professionals in the fields of toxicology, medicine, pharmacology, food, drugs, and other regulatory sciences.
Author : Nelson Durán
Publisher : Springer Science & Business Media
ISBN 13 : 1461489938
Total Pages : 415 pages
Book Rating : 4.4/5 (614 download)
Download or read book Nanotoxicology written by Nelson Durán and published by Springer Science & Business Media. This book was released on 2013-10-25 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book takes a systematic approach to nanotoxicology and the developing risk factors associated with nanosized particles during manufacture and use of nanotechnology. Beginning with a detailed introduction to engineered nanostructures, the first part of the book presents concepts and definitions of nanomaterials from quantum dots to graphene to fullerenes, with detailed discussion of functionalization, stability, and medical and biological applications. The second part critically examines methodologies used to assess cytotoxicity and genotoxicity. Coverage includes interactions with blood (erythrocytes), combinatorial and microarray techniques, cellular mechanisms, and ecotoxicology assessments. Part three describes cases studies both in vitro and in vivo for specific nanomaterials including solid lipid nanoparticles and nanostructured lipid carriers and metallic nanoparticles and metallic oxides. New information is also presented on toxicological aspects of poloxamers and polymeric nanoparticles as drug carriers as well as size effects on cytotoxicity and genotoxicity. Didactic aspects are emphasized in all chapters, making the book suitable for a broad audience ranging from advanced undergraduate and graduate students to researchers in academia and industry. In all, Nanotoxicology: Materials, Methodologies, and Assessments will provide comprehensive insight into biological and environmental interactions with nanostructures. Provides an introduction to nanostructures actually in use Describes cyto- and genotoxicity methodologies, and assesses their performance in comparison to common toxicity assays Discusses the relation of cytotoxicity and genotoxicity to ecotoxicity Presents a range of applications, from biogenic silver nanoparticles to poloxamers as drug-delivery systems, reflecting the expanding applications of nanotechnology
Author : Ramazan Asmatulu
Publisher : Newnes
ISBN 13 : 0444594582
Total Pages : 257 pages
Book Rating : 4.4/5 (445 download)
Download or read book Nanotechnology Safety written by Ramazan Asmatulu and published by Newnes. This book was released on 2013-06-12 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology is a new and emerging discipline that is multidisciplinary and interdisciplinary. The usage of nanosystems, nanomaterials, nano-devices, etc. permeates all aspects of society. Cancer targeting and curing nanosystems are being introduced into the biomedical and pharmaceutical industries; so are lightweight energy absorbing or blast-proof nanohybrid material in the aerospace, automotive and marine industries and high-efficiency energy harvesting nanomaterials, etc. Society has a vested interest in knowing how these new materials, devices and systems are changing the economy and similar landscapes. The book outlines the regulatory and environmental issues related to nanotechnology per industry, offers guidelines in assessing the risks and discusses the legal and socioeconomical issues involved. Case studies will be utilized to provide examples of the positive and negative impacts of nanotechnology. - Provides an overview and the basis for understanding the critical importance of the reactivity and efficacy of nanomaterials and the emerging role of nanotechnology in society - Explains the fundamentals, ethics, regulatory and environmental issues of nanosafety and how they shape the emerging nanotechnology industry and markets and includes extensive lists of glossary terms, terminologies and concepts needed for Material Data Safety Sheets - Discusses the relevance and specificity of nanosafety issues per industry and includes discussions on the "Homeland Security and Infrastructure Industries" of interest to society in general - Includes nanotechnology risk assessment and delineates and quantifies the risk assessment process for nanotechnology safety of paramount importance to most industries and systems - Outlines the legal and intellectual property ramifications of nanotechnology and its impact on productivity and society
Author : Marcelo Larramendy
Publisher : BoD – Books on Demand
ISBN 13 : 9535127160
Total Pages : 220 pages
Book Rating : 4.5/5 (351 download)
Download or read book Toxicology written by Marcelo Larramendy and published by BoD – Books on Demand. This book was released on 2016-10-26 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited book, Toxicology - New Aspects to This Scientific Conundrum, is intended to provide an overview on the different xenobiotics employed every day in our anthropogenic activities. We hope that this book will continue to meet the expectations and needs of all interested in the implications for the living species of known and new toxicants and to guide them in the future investigations.
Author : Alok Dhawan
Publisher : Royal Society of Chemistry
ISBN 13 : 178262158X
Total Pages : 380 pages
Book Rating : 4.7/5 (826 download)
Download or read book Nanotoxicology written by Alok Dhawan and published by Royal Society of Chemistry. This book was released on 2017-11-13 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book fills the significant nanotoxicology and nanosafety knowledge gaps and covers a broad range of topics. It targets postgraduates, academics, and practicing industrialists.
Author : Agnieszka Gajewicz
Publisher : CRC Press
ISBN 13 : 1000680886
Total Pages : 570 pages
Book Rating : 4.0/5 (6 download)
Download or read book Computational Nanotoxicology written by Agnieszka Gajewicz and published by CRC Press. This book was released on 2019-11-13 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of computational methods that support human health and environmental risk assessment of engineered nanomaterials (ENMs) has attracted great interest because the application of these methods enables us to fill existing experimental data gaps. However, considering the high degree of complexity and multifunctionality of ENMs, computational methods originally developed for regular chemicals cannot always be applied explicitly in nanotoxicology. This book discusses the current state of the art and future needs in the development of computational modeling techniques for nanotoxicology. It focuses on (i) computational chemistry (quantum mechanics, semi-empirical methods, density functional theory, molecular mechanics, molecular dynamics), (ii) nanochemoinformatic methods (quantitative structure–activity relationship modeling, grouping, read-across), and (iii) nanobioinformatic methods (genomics, transcriptomics, proteomics, metabolomics). It reviews methods of calculating molecular descriptors sufficient to characterize the structure of nanoparticles, specifies recent trends in the validation of computational methods, and discusses ways to cope with the uncertainty of predictions. In addition, it highlights the status quo and further challenges in the application of computational methods in regulation (e.g., REACH, OECD) and in industry for product development and optimization and the future directions for increasing acceptance of computational modeling for nanotoxicology.
Author : Hemant Kumar Daima
Publisher : CRC Press
ISBN 13 : 1000399974
Total Pages : 461 pages
Book Rating : 4.0/5 (3 download)
Download or read book Nanotoxicology written by Hemant Kumar Daima and published by CRC Press. This book was released on 2021-07-15 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of nanomedicine has risen quickly due to the increasing number of designer-made nanomaterials. These nanomaterials have the potential to manage diseases and change the way medicine is currently studied. However, the increased practice of using nanomaterials has shed light on how many concepts of nanomedicine and nanotoxicity have been overlooked. Nanotoxicology: Toxicity Evaluation of Nanomedicine Applications addresses the existing gaps between nanomedicine and nanotoxicity. This book also brings together up-to-date knowledge on advances toward safe-by-design nanomaterials and existing toxicity challenges. This book delivers a comprehensive coverage in the field with fundamental understanding, serving as a platform to convey essential concepts of nanotoxicology and how these concepts can be employed to develop advanced nanomaterials for a range of biomedical applications. This book is an effort to answer some of the thoughtful nanotoxicological complications and their auspicious probable solutions with new approaches and careful toxicity assessment. Key Features: Reveals novel nanoscale approaches, toxicity assessment, and biomedical applications Includes importance of nanotoxicity concepts in developing smart nanomaterials Highlights unique contributions and "A to Z" aspects on the state-of-the-art from global leaders Offers a complete package to learn fundamentals with recommendations on nanomaterials toxicity and safe-by-design nanomedicines Nanotoxicology: Toxicity Evaluation of Nanomedicine Applications illuminates the high potential of many innovative nanomaterials, ultimately demonstrating them to be promising substitutes for available therapies that can be effectively used in fighting a myriad of biomedical complications. Further, this book reports legal, ethical, safety, and regulatory issues associated with nanomaterials, which have often been neglected, if not overlooked in literature and limiting clinical translation at nanoscale level. It will equip readers with cutting-edge knowledge of promising developments in nanomedicine and nanotoxicology, along with potential future prospects.
Author : Surender K. Sharma
Publisher : Springer Nature
ISBN 13 : 3030799603
Total Pages : 480 pages
Book Rating : 4.0/5 (37 download)
Download or read book Spinel Nanoferrites written by Surender K. Sharma and published by Springer Nature. This book was released on 2021-10-29 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the complexity of spinel nanoferrites, their synthesis, physio-chemical properties and prospective applications in the area of advanced electronics, microwave devices, biotechnology as well as biomedical sciences. It presents an overview of spinel nanoferrites: synthesis, properties and applications for a wide audience: from beginners and graduate-level students up to advanced specialists in both academic and industrial sectors. There are 15 chapters organized into four main sections. The first section of the book introduces the readers to spinel ferrites and their applications in advanced electronics industry including microwave devices, whereas the second section mainly focus on the synthesis strategy and their physio-chemical properties. The last sections of the book highlight the importance of this class of nanomaterials in the field of biotechnology and biomedical sector with a special chapter on water purification.
Author : Alok Dhawan
Publisher : Humana Press
ISBN 13 : 9781627035286
Total Pages : 0 pages
Book Rating : 4.0/5 (352 download)
Download or read book Genotoxicity Assessment written by Alok Dhawan and published by Humana Press. This book was released on 2013-07-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic toxicology is recognized by geneticists and researchers concerned with the genetic impact of man-made chemicals. In Genotoxicity Assessment: Methods and Protocols, expert researchers in the field provide comprehensive genetic toxicology protocols. These include in vitro and in vivo protocols on mutation assays, cytogenetic techniques, and primary DNA damage, assays in alternate to animal models, and updated ICH guidelines. Written in the highly successful Methods in Molecular Biology series format, the chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Genotoxicity Assessment: Methods and Protocols seeks to aid research students and scientists working in regulatory toxicology as well as biomedical, biochemical and pharmaceutical sciences.
Author : Nanasaheb D. Thorat
Publisher : Elsevier
ISBN 13 : 0323850502
Total Pages : 324 pages
Book Rating : 4.3/5 (238 download)
Download or read book Nano-Pharmacokinetics and Theranostics written by Nanasaheb D. Thorat and published by Elsevier. This book was released on 2021-07-30 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nano-Pharmacokinetics and Theranostics: Advancing Cancer Therapy addresses from a comprehensive and multidisciplinary approach the translational aspects and clinical perspectives of nano-pharmacokinetics using cancer as a model disease. Nano-pharmacokinetics is emerging as an important sub discipline of nanoscience and medical sciences because of the increasing safety issues of nanosystems on living organisms. This book reports the dynamics of nanosystems in living organisms for better understanding of nanotoxicity, pharmacology, biochemistry, physiology and medicine perspectives. It further examines current progress of state-of-the art pharmacokinetics mechanisms, which will be of great help to develop more clinical-oriented nanosystems with a wide safety margin. The book is divided into three sections: the first section focuses on the concept of pharmacokinetics with state-of-the-art Nano-Pharmacokinetics (NPK). The second section looks at the engineering of nanoparticles and pharmacokinetics clinical development. The final section focuses on Nano-Pharmacokinetics and Theranostics, elaborating the basic question of how pharmacokinetics of nanomaterials relate to their end applications such as cancer therapy. Nano-Pharmacokinetics and Theranostics: Advancing Cancer Therapy will be useful to researchers in the field of nanoparticle based targeted drug delivery including pharmaceutical scientists, material scientists, chemists, nanotechnologists, biomedical scientists, and clinicians. Includes contributions from highly qualified scientists, regulatory entities, enterprises and medical practitioners to explain the long and inherently multidisciplinary pathway of nano-pharmacokinetics Describes assessment methods of nano-pharmacokinetics Examines the interface between nanomedicine and pharmacokinetics to diagnose and treat cancer
