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Methodes Biostatiques Appliquees A La Recherche Clinique En Cancerologie
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Book Synopsis Pan-cancer Integrative Molecular Portrait Towards a New Paradigm in Precision Medicine by : Christophe Le Tourneau
Download or read book Pan-cancer Integrative Molecular Portrait Towards a New Paradigm in Precision Medicine written by Christophe Le Tourneau and published by Springer. This book was released on 2015-08-27 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: This original book provides readers with an overview of the latest developments in personalized medicine clinical trials in oncology. The topics covered range from the rationale behind this new generation of clinical trials and the latest statistical models for high-throughput molecular techniques, bioinformatics, high-throughput screening molecular techniques and the challenges entailed by implementing them in daily practice. It also covers the key role of pathology in the validation of molecular results and the complex assessment of predictive biomarkers. The different topics covered are supplemented by unique concrete examples based on the SHIVA trial. The authors are all members of the French Curie Institute, one of the world’s foremost cancer research institutions.
Book Synopsis Méthodes biostatiques appliquées a la recherche clinique en cancérologie by : Andrew Kramar
Download or read book Méthodes biostatiques appliquées a la recherche clinique en cancérologie written by Andrew Kramar and published by John Libbey Eurotext. This book was released on 2011-09-01 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: En cancérologie, les méthodes statistiques sont utilisées pour résumer l’information fournie par la collecte de données issues d’études cliniques ou observationnelles, que ce soit pour l’évaluation d’un nouveau test diagnostique, d’une nouvelle stratégie de traitement, de facteurs de risque ou de facteurs pronostiques. Pour comprendre ces méthodes, il est nécessaire de connaître la population à laquelle on s’adresse, les conditions dans lesquelles les résultats ont été obtenus et si leur interprétation est correcte. Les statisticiens des centres de lutte contre le cancer sont confrontés à des questions demandant des analyses de plus en plus sophistiquées. Ce livre a pour objectif d’expliquer les méthodes biostatistiques les plus couramment utilisées en cancérologie. Les auteurs rassemblent les notions préliminaires pour appréhender la variabilité statistique et les statistiques descriptives avant de passer à la spécificité de la cancérologie. La présentation des tests d’hypothèses permettra au lecteur de bien intégrer les démarches nécessaires pour planifier une étude clinique. Sont exposés les aspects pratiques essentiels à la rédaction d’un plan d’analyse statistique et d’un rapport statistique, ainsi que les outils nécessaires pour entreprendre les analyses statistiques. Les domaines d’émergence (statistiques bayésiennes, essais phase 0, génomique et génétique) ne sont pas en reste. Illustré de nombreux exemples, cet ouvrage permettra de mieux situer les exigences statistiques par rapport à l’évaluation des projets de recherche en cancérologie et sera un guide de référence pour les statisticiens travaillant dans tous les domaines de l’oncologie.
Book Synopsis Méthodes biostatistiques appliquées à la recherche clinique en cancérologie by : Sophie Gourgou
Download or read book Méthodes biostatistiques appliquées à la recherche clinique en cancérologie written by Sophie Gourgou and published by . This book was released on 2021 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: Les méthodes biostatistiques les plus couramment utilisées en cancérologie sont expliquées. Des notions préliminaires sont présentées afin d'aider à appréhender la variabilité et les statistiques descriptives. Illustré de nombreux exemples, l'ouvrage permet d'intégrer les démarches utiles pour planifier une étude clinique et de mieux situer les exigenceschiffrées en oncologie.
Book Synopsis Méthodes Biostatistiques appliquées à la recherche clinique en cancérologie by : Sophie Gourgou
Download or read book Méthodes Biostatistiques appliquées à la recherche clinique en cancérologie written by Sophie Gourgou and published by John Libbey Eurotext. This book was released on 2021-11-04 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: Une nouvelle édition actualisée et enrichie du guide de référence des investigateurs d'études et d'essais cliniques en cancérologie. Un outil indispensable : - pour mieux situer les exigences statistiques (hypothèses et analyses) lors de l’élaboration de projets de recherche en cancérologie ; - pour mesurer les stratégies thérapeutiques. Nos 3 coordonnateurs, Sophie Gourgou, Xavier Paoletti et Simone Mathoulin-Pélissier, ont réussi à rassembler les auteurs les plus aguerris pour ce nouvel opus, destiné aux biostatisticiens, cliniciens, biologistes, pharmaciens, datamanagers, étudiants impliqués dans le domaine de la cancérologie
Book Synopsis Méthodes Biostatistiques appliquées à la recherche clinique en cancérologie by : Sophie Gourgou
Download or read book Méthodes Biostatistiques appliquées à la recherche clinique en cancérologie written by Sophie Gourgou and published by . This book was released on 2022 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Computational Systems Biology of Cancer by : Emmanuel Barillot
Download or read book Computational Systems Biology of Cancer written by Emmanuel Barillot and published by CRC Press. This book was released on 2012-08-25 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: The future of cancer research and the development of new therapeutic strategies rely on our ability to convert biological and clinical questions into mathematical models—integrating our knowledge of tumour progression mechanisms with the tsunami of information brought by high-throughput technologies such as microarrays and next-generation sequencing. Offering promising insights on how to defeat cancer, the emerging field of systems biology captures the complexity of biological phenomena using mathematical and computational tools. Novel Approaches to Fighting Cancer Drawn from the authors’ decade-long work in the cancer computational systems biology laboratory at Institut Curie (Paris, France), Computational Systems Biology of Cancer explains how to apply computational systems biology approaches to cancer research. The authors provide proven techniques and tools for cancer bioinformatics and systems biology research. Effectively Use Algorithmic Methods and Bioinformatics Tools in Real Biological Applications Suitable for readers in both the computational and life sciences, this self-contained guide assumes very limited background in biology, mathematics, and computer science. It explores how computational systems biology can help fight cancer in three essential aspects: Categorising tumours Finding new targets Designing improved and tailored therapeutic strategies Each chapter introduces a problem, presents applicable concepts and state-of-the-art methods, describes existing tools, illustrates applications using real cases, lists publically available data and software, and includes references to further reading. Some chapters also contain exercises. Figures from the text and scripts/data for reproducing a breast cancer data analysis are available at www.cancer-systems-biology.net.
Book Synopsis Adjuvant Therapy for Breast Cancer by : Monica Castiglione
Download or read book Adjuvant Therapy for Breast Cancer written by Monica Castiglione and published by Springer Science & Business Media. This book was released on 2009-07-11 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adjuvant treatment is administered prior to or as follow up to surgical procedures for breast cancer. Proven success in using medical therapies allowing for breast conserving procedures or reducing risk of occurrence. Although there has been much progress towards a cure, including the introduction of new targeted therapies, metastasizing cancer remains highly incurable.
Book Synopsis Méthodes biostatistiques appliquées à la recherche clinique en cancérologie by : Andrew Kramar
Download or read book Méthodes biostatistiques appliquées à la recherche clinique en cancérologie written by Andrew Kramar and published by John Libbey Eurotext. This book was released on 2011 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Chemoinformatics and Advanced Machine Learning Perspectives: Complex Computational Methods and Collaborative Techniques by : Lodhi, Huma
Download or read book Chemoinformatics and Advanced Machine Learning Perspectives: Complex Computational Methods and Collaborative Techniques written by Lodhi, Huma and published by IGI Global. This book was released on 2010-07-31 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book is a timely compendium of key elements that are crucial for the study of machine learning in chemoinformatics, giving an overview of current research in machine learning and their applications to chemoinformatics tasks"--Provided by publisher.
Book Synopsis Systems Biology of Cancer by : Sam Thiagalingam
Download or read book Systems Biology of Cancer written by Sam Thiagalingam and published by Cambridge University Press. This book was released on 2015-04-09 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of the current systems biology-based knowledge and the experimental approaches for deciphering the biological basis of cancer.
Download or read book Atlas of Cancer written by Maurie Markman and published by Current Medicine Group. This book was released on 2008-06-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of the Atlas of Cancer highlights the major features of current cancer management, and clearly presents fundamental facts regarding our understanding of the etiology and pathophysiology of malignant disease.
Book Synopsis Principal Manifolds for Data Visualization and Dimension Reduction by : Alexander N. Gorban
Download or read book Principal Manifolds for Data Visualization and Dimension Reduction written by Alexander N. Gorban and published by Springer Science & Business Media. This book was released on 2007-09-11 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book starts with the quote of the classical Pearson definition of PCA and includes reviews of various methods: NLPCA, ICA, MDS, embedding and clustering algorithms, principal manifolds and SOM. New approaches to NLPCA, principal manifolds, branching principal components and topology preserving mappings are described. Presentation of algorithms is supplemented by case studies. The volume ends with a tutorial PCA deciphers genome.
Book Synopsis Chemical Analysis by : Francis Rouessac
Download or read book Chemical Analysis written by Francis Rouessac and published by John Wiley & Sons. This book was released on 2013-05-06 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated, Chemical Analysis: Second Edition is an essential introduction to a wide range of analytical techniques and instruments. Assuming little in the way of prior knowledge, this text carefully guides the reader through the more widely used and important techniques, whilst avoiding excessive technical detail. Provides a thorough introduction to a wide range of the most important and widely used instrumental techniques Maintains a careful balance between depth and breadth of coverage Includes examples, problems and their solutions Includes coverage of latest developments including supercritical fluid chromatography and capillary electrophoresis
Book Synopsis Beating Back the Devil by : Maryn McKenna
Download or read book Beating Back the Devil written by Maryn McKenna and published by Simon and Schuster. This book was released on 2008-06-17 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: The universal human instinct is to run from an outbreak of disease like Ebola. These doctors run toward it. Their job is to stop epidemics from happening. They are the disease detective corps of the US Centers for Disease Control and Prevention (CDC), the federal agency that tracks and tries to prevent disease outbreaks and bioterrorist attacks around the world. They are formally called the Epidemic Intelligence Service (EIS)—a group founded more than fifty years ago out of fear that the Korean War might bring the use of biological weapons—and, like intelligence operatives in the traditional sense, they perform their work largely in anonymity. They are not household names, but over the years they were first to confront the outbreaks that became known as hantavirus, Ebola, and AIDS. Every day they work to protect us by hunting down the deadly threats that we forget until they dominate our headlines, West Nile virus, anthrax, and SARS among others. In this riveting narrative, Maryn McKenna—the only journalist ever given full access to the EIS in its fifty-three-year history—follows the first class of disease detectives to come to the CDC after September 11, the first to confront not just naturally occurring outbreaks but the man-made threat of bioterrorism. They are talented researchers—many with young families—who trade two years of low pay and extremely long hours for the chance to be part of the group that are on the frontlines, in the yellow suits and masks, that has helped eradicate smallpox, push back polio, and solve the first major outbreaks of Legionnaires’ disease, toxic shock syndrome, and E. coli O157 and works to battle every new disease before it becomes an epidemic. Urgent, exhilarating, and compelling, Beating Back the Devil takes you inside the world of these medical detectives who are trying to stop the next epidemic—before the epidemics stop us.
Download or read book Geosimulation written by Itzhak Benenson and published by John Wiley & Sons. This book was released on 2004-08-20 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Geosimulation is hailed as ‘the next big thing’ in geographic modelling for urban studies. This book presents readers with an overview of this new and innovative field by introducing the spatial modelling environment and describing the latest research and development using cellular automata and multi-agent systems. Extensive case studies and working code is available from an associated website which demonstrate the technicalities of geosimulation, and provide readers with the tools to carry out their own modelling and testing. The first book to treat urban geosimulation explicitly, integrating socio-economic and environmental modelling approaches Provides the reader with a sound theoretical base in the science of geosimulation as well as applied material on the construction of geosimulation models Cross-references to an author-maintained associated website with downloadable working code for readers to apply the models presented in the book Visit the Author's Website for further information on Geosimulation, Geographic Automata Systems and Geographic Automata Software http://www.geosimulationbook.com
Book Synopsis Yearbook of International Organizations by :
Download or read book Yearbook of International Organizations written by and published by . This book was released on 1978 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Toward a Social Report by : United States. Department of Health, Education, and Welfare
Download or read book Toward a Social Report written by United States. Department of Health, Education, and Welfare and published by . This book was released on 1969 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: Report on a survey of the standard of living and living conditions in the USA - covers medical care, social mobility, physical environment, welfare, social policy, income distribution, poverty, education, safety, discrimination against Blacks and other minority groups, intergroup relations, social participation, human rights, the administration of justice, etc.
